Recombinant viral vectors are extensively employed as gene delivery vehicles across various settings such as cellular studies, animal models, and gene therapy. They provide an array of functions such as monitoring cell functions, manipulating the expression of target genes, and changing physiological state of specific cell populations, etc.
Viral vectors differ in their suitability for different applications, which depends on factors including size of the transgene, route of delivery, tropism, and regulation of gene expression. To facilitate the utilization of viral technology, Boston Children’s Hospital Viral Core provides custom AAV and lentiviral vector production service, as well as expert consultations in selecting, designing, and using viral vectors.