This page is dedicated to the Severe Asthma research study, one of over 60 studies supported by the Boston Children’s Rare Disease Collaborative (CRDC). For more information about the CRDC, please visit our home page. Established in 2018, the CRDC supports pediatric rare disease research and provides families with genetic diagnoses that enable personalized treatments, including precision medicine and targeted therapies.

Elana Crestani headshot
Elena Crestani
Assistant Professor, Harvard Medical School
Attending Physician, Allergy and Asthma Program

The Severe Asthma research study was established in 2025 and is led by Drs. Elena Crestani and Jonathan Gaffin.