The TIS was established in order to identify and support the development of faculty‐scientists who will become the national and international leaders in the translational research paradigm. Major highlights of this program include providing individuals with the necessary financial, time, and educational resources to be able to conduct meaningful translational research. Success of this program will 1) facilitate the rapid translation of discovery sciences into human trials; 2) facilitate the utilization of human patient resources for the purpose of advancing scientific discovery; and 3) position Boston Children’s Hospital for successful competition for NIH, disease‐specific foundation, pharmaceutical, and philanthropy financial support.