Sophia Koutsogiannaki

Publications

1. Dexmedetomidine directly binds to and inhibits Toll-like receptor 4. Int Immunopharmacol. 2024 Nov 15; 141:112975. View Abstract
2. Mechanism of isoflurane-mediated breast cancer growth in vivo. Oncol Lett. 2024 Jun; 27(6):287. View Abstract
3. The landscape of immune dysregulation in pediatric sepsis at a single-cell resolution. Clin Immunol. 2024 May; 262:110175. View Abstract
4. Cystic Fibrosis Mice Are Highly Susceptible to Repeated Acute Pseudomonas aeruginosa Pneumonia after Intranasal Inoculation. Biomed Res Int. 2024; 2024:4769779. View Abstract
5. The landscape of immune dysregulation in pediatric sepsis at a single-cell resolution. bioRxiv. 2024 Jan 19. View Abstract
6. Age-dependent transcriptomic profiles of leukocytes in pediatric population. Clin Immunol. 2023 10; 255:109728. View Abstract
7. Differential effects of dexmedetomidine on Gram-positive and Gram-negative bacterial killing and phagocytosis. Int Immunopharmacol. 2023 Jul; 120:110327. View Abstract
8. CD11c regulates neutrophil maturation. Blood Adv. 2023 04 11; 7(7):1312-1325. View Abstract
9. GltS regulates biofilm formation in methicillin-resistant Staphylococcus aureus. Commun Biol. 2022 11 23; 5(1):1284. View Abstract
10. aDß2 as a novel target of experimental polymicrobial sepsis. Front Immunol. 2022; 13:1059996. View Abstract
11. Complement-regulatory biomaterial coatings: Activity and selectivity profile of the factor H-binding peptide 5C6. Acta Biomater. 2023 01 01; 155:123-138. View Abstract
12. Propofol directly binds to and inhibits TLR7. FASEB J. 2022 08; 36(8):e22481. View Abstract
13. Isoflurane attenuates sepsis-associated lung injury. Biochem Biophys Res Commun. 2022 04 09; 599:127-133. View Abstract
14. Translational Role of Rodent Models to Study Ventilator-Induced Lung Injury. Transl Perioper Pain Med. 2021 Dec; 8(4):404-415. View Abstract
15. Neutrophil and T Cell Functions in Patients with Congenital Heart Diseases: A Review. Pediatr Cardiol. 2021 Oct; 42(7):1478-1482. View Abstract
16. Pattern recognition receptors as therapeutic targets for bacterial, viral and fungal sepsis. Int Immunopharmacol. 2021 Sep; 98:107909. View Abstract
17. The Role of Anesthetic Selection in Perioperative Bleeding. Biomed Res Int. 2021; 2021:5510634. View Abstract
18. The Characterization of Postoperative Mechanical Respiratory Requirement in Neonates and Infants Undergoing Cardiac Surgery on Cardiopulmonary Bypass in a Single Tertiary Institution. J Cardiothorac Vasc Anesth. 2022 01; 36(1):215-221. View Abstract
19. Anesthetics isoflurane and sevoflurane attenuate flagellin-mediated inflammation in the lung. Biochem Biophys Res Commun. 2021 06 11; 557:254-260. View Abstract
20. The Microbial Flora in an Experimental Polymicrobial Abdominal Sepsis Model Probed by 16S rRNA Sequencing. Transl Perioper Pain Med. 2021; 8(1):305-311. View Abstract
21. Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes. Clin Immunol. 2021 01; 222:108635. View Abstract
22. The effect of anesthetics on toll like receptor 9. FASEB J. 2020 11; 34(11):14645-14654. View Abstract
23. In Vitro Model of Stretch-Induced Lung Injury to Study Different Lung Ventilation Regimens and the Role of Sedatives. Transl Perioper Pain Med. 2020; 7(3):258-264. View Abstract
24. COVID-19 pathophysiology: A review. Clin Immunol. 2020 06; 215:108427. View Abstract
25. Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system. FASEB J. 2019 12; 33(12):14528-14541. View Abstract
26. The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction. FASEB J. 2019 11; 33(11):12668-12679. View Abstract
27. The Outcomes of Pediatric Hematopoietic Stem Cell Transplantation Recipients Requiring Intensive Care Unit Admission- A Single Center Experience. Transl Perioper Pain Med. 2019; 6(3):75-80. View Abstract
28. Volatile anesthetics affect macrophage phagocytosis. PLoS One. 2019; 14(5):e0216163. View Abstract
29. The Use of Volatile Anesthetics as Sedatives for Acute Respiratory Distress Syndrome. Transl Perioper Pain Med. 2019; 6(2):27-38. View Abstract
30. Protective Effects of the Complement Inhibitor Compstatin CP40 in Hemorrhagic Shock. Shock. 2019 01; 51(1):78-87. View Abstract
31. Safety profile after prolonged C3 inhibition. Clin Immunol. 2018 12; 197:96-106. View Abstract
32. Volatile Anesthetic Attenuates Phagocyte Function and Worsens Bacterial Loads in Wounds. J Surg Res. 2019 01; 233:323-330. View Abstract
33. Incidence and Risk Factors for Perioperative Cardiovascular and Respiratory Adverse Events in Pediatric Patients With Congenital Heart Disease Undergoing Noncardiac Procedures. Anesth Analg. 2018 09; 127(3):724-729. View Abstract
34. Volatile Anesthetic Isoflurane Attenuates Liver Injury in Experimental Polymicrobial Sepsis Model. Transl Perioper Pain Med. 2018; 5(3):63-74. View Abstract
35. Unanticipated hospital admission in pediatric patients with congenital heart disease undergoing ambulatory noncardiac surgical procedures. Paediatr Anaesth. 2018 07; 28(7):607-611. View Abstract
36. Validation of a Mathematical Model of Bidirectional Glenn Circulation With Aortopulmonary Collaterals and the Implications for QP/QS Calculation. J Cardiothorac Vasc Anesth. 2018 02; 32(1):395-401. View Abstract
37. From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. Toxicol Sci. 2017 04 01; 156(2):402-411. View Abstract
38. Structural Implications for the Formation and Function of the Complement Effector Protein iC3b. J Immunol. 2017 04 15; 198(8):3326-3335. View Abstract
39. The Differential Effects of Anesthetics on Bacterial Behaviors. PLoS One. 2017; 12(1):e0170089. View Abstract
40. Intravenous anesthetic propofol binds to 5-lipoxygenase and attenuates leukotriene B4 production. FASEB J. 2017 04; 31(4):1584-1594. View Abstract
41. Pediatric Perioperative Stress Responses and Anesthesia. Transl Perioper Pain Med. 2017; 2(1):1-12. View Abstract
42. The effect of different anesthetics on tumor cytotoxicity by natural killer cells. Toxicol Lett. 2017 Jan 15; 266:23-31. View Abstract
43. Method development and validation for the quantitation of the complement inhibitor Cp40 in human and cynomolgus monkey plasma by UPLC-ESI-MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 15; 1041-1042:19-26. View Abstract
44. Complement C3 inhibitor Cp40 attenuates xenoreactions in pig hearts perfused with human blood. Xenotransplantation. 2017 01; 24(1). View Abstract
45. Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3. J Clin Periodontol. 2016 Mar; 43(3):238-49. View Abstract
46. Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria. Blood. 2015 Aug 13; 126(7):891-4. View Abstract
47. Effects of cadmium and 17ß-estradiol on Mytilus galloprovincialis redox status. Prooxidant-antioxidant balance (PAB) as a novel approach in biomonitoring of marine environments. Mar Environ Res. 2015 Feb; 103:80-8. View Abstract
48. Oxidative stress parameters induced by exposure to either cadmium or 17ß-estradiol on Mytilus galloprovincialis hemocytes. The role of signaling molecules. Aquat Toxicol. 2014 Jan; 146:186-95. View Abstract
49. Effect of 17ß-estradiol on adhesion of Mytilus galloprovincialis hemocytes to selected substrates. Role of alpha2 integrin subunit. Fish Shellfish Immunol. 2011 Jul; 31(1):73-80. View Abstract
50. Signaling molecules involved in immune responses in mussels. Invertebrate Survival Journal. 2010; 7:11-21. View Abstract
51. Oxidative effects of inorganic and organic contaminants on haemolymph of mussels. Comp Biochem Physiol C Toxicol Pharmacol. 2009 May; 149(4):631-9. View Abstract
52. Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS. Aquat Toxicol. 2006 Jul 20; 78(4):315-24. View Abstract
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