Information

Related Research Units

Anesthesiology, Critical Care and Pain Medicine Research
Cardiac Anesthesia Research

Publications

  1. The Anesthesia Perioperative "Call for Help"-Experience at a Quaternary Pediatric Medical Center: Analysis of 67,564 Anesthesia Encounters. Anesth Analg. 2018 07; 127(1):126-133. View Abstract
  2. Anesthesiologist- and System-Related Risk Factors for Risk-Adjusted Pediatric Anesthesia-Related Cardiac Arrest. Anesth Analg. 2016 Feb; 122(2):482-9. View Abstract
  3. Research at the Harvard Anesthesia Departments. Anesthesiology. 2014 Dec; 121(6):1141-3. View Abstract
  4. Infantile postoperative encephalopathy: perioperative factors as a cause for concern. Pediatrics. 2014 Mar; 133(3):e751-7. View Abstract
  5. High dose dexmedetomidine as the sole sedative for pediatric MRI. Paediatr Anaesth. 2008 May; 18(5):403-11. View Abstract
  6. The frequency of anesthesia-related cardiac arrests in patients with congenital heart disease undergoing cardiac surgery. Anesth Analg. 2007 Aug; 105(2):335-43. View Abstract
  7. Of mice and men: should we extrapolate rodent experimental data to the care of human neonates? Anesthesiology. 2005 Apr; 102(4):866-8; author reply 868-9. View Abstract
  8. Intraoperative hyperglycemia during infant cardiac surgery is not associated with adverse neurodevelopmental outcomes at 1, 4, and 8 years. Anesthesiology. 2004 Jun; 100(6):1345-52. View Abstract
  9. Time course of early induction of intracellular adhesion molecule-1 messenger RNA during reperfusion, following cardiopulmonary bypass with hypothermic circulatory arrest in lambs. Pediatr Crit Care Med. 2003 Jan; 4(1):83-8. View Abstract
  10. Stress response in infants undergoing cardiac surgery: a randomized study of fentanyl bolus, fentanyl infusion, and fentanyl-midazolam infusion. Anesth Analg. 2001 Apr; 92(4):882-90. View Abstract
  11. Sialyl lewis oligosaccharide preserves cardiopulmonary and endothelial function after hypothermic circulatory arrest in lambs. J Thorac Cardiovasc Surg. 2000 Aug; 120(2):230-7. View Abstract
  12. Synthetic antifibrinolytics are not associated with an increased incidence of baffle fenestration closure after the modified Fontan procedure. J Cardiothorac Vasc Anesth. 2000 Jun; 14(3):257-9. View Abstract
  13. Developmental and neurological status of children at 4 years of age after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. Circulation. 1999 Aug 03; 100(5):526-32. View Abstract
  14. Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. Stroke. 1999 Jan; 30(1):134-9. View Abstract
  15. Effects of a monoclonal antibody to P-selectin on recovery of neonatal lamb hearts after cold cardioplegic ischemia. Circulation. 1998 Nov 10; 98(19 Suppl):II391-7; discussion II397-8. View Abstract
  16. Neurologic sequelae associated with deep hypothermic circulatory arrest. Ann Thorac Surg. 1998 Jun; 65(6 Suppl):S65-9; discussion S69-70, S74-6. View Abstract
  17. ICAM-1 dependent pathway is not involved in the development of neuronal apoptosis after transient focal cerebral ischemia. Brain Res. 1998 Jan 12; 780(2):337-41. View Abstract
  18. Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg. 1997 Dec; 114(6):991-1000; discussion 1000-1. View Abstract
  19. Soluble adhesion molecules in infants and children undergoing cardiopulmonary bypass. Circulation. 1997 Nov 04; 96(9 Suppl):II-352-7. View Abstract
  20. Hypoxia enhances induction of endothelial ICAM-1: role for metabolic acidosis and proteasomes. Am J Physiol. 1997 11; 273(5):C1571-80. View Abstract
  21. The limits of detectable cerebral perfusion by transcranial Doppler sonography in neonates undergoing deep hypothermic low-flow cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1997 Oct; 114(4):594-600. View Abstract
  22. Induction of aquaporin-1 mRNA following cardiopulmonary bypass and reperfusion. Mol Med. 1997 Sep; 3(9):600-9. View Abstract
  23. The influence of cardiopulmonary bypass on ionized magnesium in neonates, infants, and children undergoing repair of congenital heart lesions. Anesth Analg. 1997 Mar; 84(3):497-500. View Abstract
  24. Perioperative electroencephalographic seizures in infants undergoing repair of complex congenital cardiac defects. Electroencephalogr Clin Neurophysiol. 1997 Jan; 102(1):27-36. View Abstract
  25. Blockade of selectin-mediated leukocyte adhesion improves postischemic function in lamb hearts. Ann Thorac Surg. 1996 Nov; 62(5):1295-300. View Abstract
  26. Tracheal extubation of children in the operating room after atrial septal defect repair as part of a clinical practice guideline. Anesth Analg. 1996 May; 82(5):988-93. View Abstract
  27. Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia-reperfusion injury. Ann Neurol. 1996 May; 39(5):618-24. View Abstract
  28. Cerebral oxygenation during hypothermic cardiopulmonary bypass: clinical findings support mathematical model. Anesthesiology. 1996 Apr; 84(4):1008-9. View Abstract
  29. Adhesion molecules and inflammation: the next targets for perioperative organ protection? Anesth Analg. 1995 Dec; 81(6):1123-4. View Abstract
  30. Comparing two strategies of cardiopulmonary bypass cooling on jugular venous oxygen saturation in neonates and infants. Ann Thorac Surg. 1995 Nov; 60(5):1198-202. View Abstract
  31. Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants. A comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation. 1995 Oct 15; 92(8):2226-35. View Abstract
  32. Anti-CD18 attenuates deleterious effects of cardiopulmonary bypass and hypothermic circulatory arrest in piglets. J Card Surg. 1995 Jul; 10(4 Suppl):407-17. View Abstract
  33. Transcatheter closure of ventricular septal defects: hemodynamic instability and anesthetic management. Anesth Analg. 1995 Jun; 80(6):1076-82. View Abstract
  34. Coagulation factor deficiencies during initiation of extracorporeal membrane oxygenation. J Pediatr. 1995 Jun; 126(6):900-4. View Abstract
  35. Cerebral oxygen supply and utilization during infant cardiac surgery. Ann Neurol. 1995 Apr; 37(4):488-97. View Abstract
  36. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. N Engl J Med. 1995 Mar 02; 332(9):549-55. View Abstract
  37. Pulmonary vascular resistance in infants after cardiac surgery: role of carbon dioxide and hydrogen ion. Crit Care Med. 1995 Mar; 23(3):568-74. View Abstract
  38. Effects of cerebroplegic solutions during hypothermic circulatory arrest and short-term recovery. J Thorac Cardiovasc Surg. 1994 Aug; 108(2):291-301. View Abstract
  39. Effects of aprotinin on acute recovery of cerebral metabolism in piglets after hypothermic circulatory arrest. Ann Thorac Surg. 1994 Jul; 58(1):146-53. View Abstract
  40. Delivery and monitoring of inhaled nitric oxide in patients with pulmonary hypertension. Crit Care Med. 1994 Jun; 22(6):930-8. View Abstract
  41. Induction of intercellular adhesion molecule-1 and E-selectin mRNA in heart and skeletal muscle of pediatric patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1994 May; 107(5):1183-92. View Abstract
  42. Regional cerebral perfusion abnormalities after cardiac operations. Single photon emission computed tomography (SPECT) findings in children with postoperative movement disorders. J Thorac Cardiovasc Surg. 1994 Apr; 107(4):1036-43. View Abstract
  43. Effects of MK-801 and NBQX on acute recovery of piglet cerebral metabolism after hypothermic circulatory arrest. J Cereb Blood Flow Metab. 1994 Jan; 14(1):156-65. View Abstract
  44. Anesthesia in a neonate with tamponade due to massive pericardial effusion. Anesth Analg. 1994 Jan; 78(1):169-71. View Abstract
  45. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med. 1993 Oct 07; 329(15):1057-64. View Abstract
  46. Recovery of cerebral blood flow and energy state in piglets after hypothermic circulatory arrest versus recovery after low-flow bypass. J Thorac Cardiovasc Surg. 1993 Oct; 106(4):671-85. View Abstract
  47. Real-time gas-exchange measurement of oxygen consumption in neonates and infants after cardiac surgery. Crit Care Med. 1993 Sep; 21(9):1369-75. View Abstract
  48. Relation of pH strategy and developmental outcome after hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 1993 Aug; 106(2):362-8. View Abstract
  49. Effects of pH on brain energetics after hypothermic circulatory arrest. Ann Thorac Surg. 1993 May; 55(5):1093-103. View Abstract
  50. Anti-CD18 attenuates myocardial stunning in the isolated neonatal lamb heart. J Card Surg. 1993 Mar; 8(2 Suppl):313-5. View Abstract
  51. Acute right ventricular failure after pulmonary hypertensive responses to airway instrumentation: effect of fentanyl dose. Anesthesiology. 1993 Feb; 78(2):372-6. View Abstract
  52. Factors associated with choreoathetosis after cardiopulmonary bypass in children with congenital heart disease. Circulation. 1992 Nov; 86(5 Suppl):II118-26. View Abstract
  53. Effect of antibody to leukocyte adhesion molecule CD18 on recovery of neonatal lamb hearts after 2 hours of cold ischemia. Circulation. 1992 Nov; 86(5 Suppl):II364-70. View Abstract
  54. Temperature monitoring during CPB in infants: does it predict efficient brain cooling? Ann Thorac Surg. 1992 Oct; 54(4):749-54. View Abstract
  55. Coagulation defects in neonates during cardiopulmonary bypass. Ann Thorac Surg. 1992 Sep; 54(3):541-6. View Abstract
  56. Transesophageal echocardiography in pediatric cardiac surgery. Anesthesiology. 1992 Sep; 77(3):610-1. View Abstract
  57. Halothane-morphine compared with high-dose sufentanil for anesthesia and postoperative analgesia in neonatal cardiac surgery. N Engl J Med. 1992 Jan 02; 326(1):1-9. View Abstract
  58. Transcatheter closure of atrial septal defects: hemodynamic complications and anesthetic management. Anesth Analg. 1992 Jan; 74(1):44-50. View Abstract
  59. Anesthesia laboratory for the pediatric operating room. Int Anesthesiol Clin. 1992; 30(3):177-88. View Abstract
  60. Pro: deep hypothermic circulatory arrest is preferable to low-flow bypass. J Cardiothorac Vasc Anesth. 1991 Dec; 5(6):635-7. View Abstract
  61. Cardiac dysrhythmias in pediatric patients during anesthesia and the role of oximetry and capnography. Anesth Analg. 1991 Dec; 73(6):686-8. View Abstract
  62. High-dose fentanyl reduces intraoperative ventricular fibrillation in neonates with hypoplastic left heart syndrome. J Clin Anesth. 1991 Jul-Aug; 3(4):295-300. View Abstract
  63. Cognitive development of children following early repair of transposition of the great arteries using deep hypothermic circulatory arrest. Pediatrics. 1991 May; 87(5):701-7. View Abstract
  64. Invited letter concerning: No flow during cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1991 Feb; 101(2):364-5. View Abstract
  65. Hormonal-metabolic stress responses in neonates undergoing cardiac surgery. Anesthesiology. 1990 Oct; 73(4):661-70. View Abstract
  66. The neonate with critical congenital heart disease: repair--a surgical challenge. J Thorac Cardiovasc Surg. 1989 Nov; 98(5 Pt 2):869-75. View Abstract
  67. Perioperative cardiovascular collapse in a patient previously treated with doxorubicin. Anesth Analg. 1989 Jul; 69(1):138-9. View Abstract
  68. Velocity of the creatine kinase reaction in the neonatal rabbit heart: role of mitochondrial creatine kinase. Biochemistry. 1988 Mar 22; 27(6):2165-72. View Abstract
  69. Ventilatory management assisted by cardiopulmonary bypass for distal tracheal reconstruction in a neonate. Anesthesiology. 1988 Feb; 68(2):270-1. View Abstract
  70. Pain and its effects in the human neonate and fetus. N Engl J Med. 1987 Nov 19; 317(21):1321-9. View Abstract
  71. The effect of halothane on the steady-state levels of high-energy phosphates in the neonatal heart. Anesthesiology. 1987 Aug; 67(2):231-5. View Abstract
  72. Deep hypothermic circulatory arrest: a review of pathophysiology and clinical experience as a basis for anesthetic management. J Cardiothorac Anesth. 1987 Apr; 1(2):137-55. View Abstract
  73. Pulmonary and systemic hemodynamic effects of nitrous oxide in infants with normal and elevated pulmonary vascular resistance. Anesthesiology. 1986 Oct; 65(4):374-8. View Abstract
  74. First-stage palliation of hypoplastic left heart syndrome. The importance of coarctation and shunt size. J Thorac Cardiovasc Surg. 1986 Jul; 92(1):6-13. View Abstract
  75. Intraoperative tension pneumopericardium with tamponade after ligation of patent ductus arteriosus in a premature neonate. Anesthesiology. 1986 May; 64(5):641-3. View Abstract
  76. Anesthesia for hypoplastic left heart syndrome: use of high-dose fentanyl in 30 neonates. Anesth Analg. 1986 Feb; 65(2):127-32. View Abstract
  77. Blunting of stress responses in the pulmonary circulation of infants by fentanyl. Anesth Analg. 1985 Dec; 64(12):1137-42. View Abstract
  78. Deep hypothermic circulatory arrest: current status and future directions. Mt Sinai J Med. 1985 Sep; 52(7):541-7. View Abstract
  79. Pulmonary and systemic hemodynamic responses to fentanyl in infants. Anesth Analg. 1985 May; 64(5):483-6. View Abstract
  80. Pulmonary and systemic hemodynamic responses to ketamine in infants with normal and elevated pulmonary vascular resistance. Anesthesiology. 1985 Mar; 62(3):287-93. View Abstract
  81. Perioperative complications in patients with anthracycline chemotherapeutic agents. Can Anaesth Soc J. 1985 Mar; 32(2):149-57. View Abstract
  82. Anesthetic complications in surgery for congenital heart disease. Anesth Analg. 1984 Jul; 63(7):657-64. View Abstract
  83. Fentanyl- and sufentanil-oxygen-pancuronium anesthesia for cardiac surgery in infants. Anesth Analg. 1984 Feb; 63(2):117-24. View Abstract

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