Joshua Mayourian

Publications

1. Artificial Intelligence-Enabled Electrocardiograms: Do 15-Lead Studies Improve Model Performance? JACC Adv. 2025 Jun 25; 4(7):101866. View Abstract
2. Artificial Intelligence-Enabled ECG to Detect Congenitally Corrected Transposition of the Great Arteries. Pediatr Cardiol. 2025 Jun 16. View Abstract
3. Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy. Nat Commun. 2025 Apr 16; 16(1):3604. View Abstract
4. Development and Validation of a Novel Deep Learning Model to Predict Pharmacologic Closure of Patent Ductus Arteriosus in Premature Infants. J Am Soc Echocardiogr. 2025 Apr 11. View Abstract
5. Electrocardiogram-based deep learning to predict left ventricular systolic dysfunction in paediatric and adult congenital heart disease in the USA: a multicentre modelling study. Lancet Digit Health. 2025 Apr; 7(4):e264-e274. View Abstract
6. Electrocardiogram-based deep learning to predict mortality in paediatric and adult congenital heart disease. Eur Heart J. 2025 Mar 03; 46(9):856-868. View Abstract
7. Expert-Level Automated Diagnosis of the Pediatric ECG Using a Deep Neural Network. JACC Clin Electrophysiol. 2025 Mar 01. View Abstract
8. Artificial Intelligence-Enabled Electrocardiogram Predicts Sudden Cardiac Death in Repaired Tetralogy of Fallot. JACC Clin Electrophysiol. 2025 Mar; 11(3):593-595. View Abstract
9. Cardiac Applications of CRISPR/AAV-Mediated Precise Genome Editing. bioRxiv. 2024 Dec 04. View Abstract
10. Electrocardiogram-Based Deep Learning to Predict Mortality in Repaired Tetralogy of Fallot. JACC Clin Electrophysiol. 2024 Dec; 10(12):2600-2612. View Abstract
11. Deep Learning-Based Electrocardiogram Analysis Predicts Biventricular Dysfunction and Dilation in Congenital Heart Disease. J Am Coll Cardiol. 2024 Aug 27; 84(9):815-828. View Abstract
12. Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy. Res Sq. 2024 Jul 19. View Abstract
13. Efficient and reproducible generation of human iPSC-derived cardiomyocytes and cardiac organoids in stirred suspension systems. Nat Commun. 2024 Jul 15; 15(1):5929. View Abstract
14. Pediatric Electrocardiogram-Based Deep Learning to Predict Secundum Atrial Septal Defects. Pediatr Cardiol. 2025 Jun; 46(5):1235-1240. View Abstract
15. Development and Validation of a Mortality Risk Score for Repaired Tetralogy of Fallot. J Am Heart Assoc. 2024 Jun 18; 13(12):e034871. View Abstract
16. Child opportunity and outcomes in pediatric critical asthma: A multicenter analysis. J Allergy Clin Immunol Pract. 2024 Aug; 12(8):2187-2189. View Abstract
17. Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactor. bioRxiv. 2024 Feb 28. View Abstract
18. Pediatric ECG-Based Deep Learning to Predict Left Ventricular Dysfunction and Remodeling. Circulation. 2024 03 19; 149(12):917-931. View Abstract
19. Social Drivers of Health and Pediatric Extracorporeal Membrane Oxygenation Outcomes. Pediatrics. 2023 Dec 01; 152(6). View Abstract
20. An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Sci Transl Med. 2023 06 21; 15(701):eabq7839. View Abstract
21. Insight into the Role of the Child Opportunity Index on Surgical Outcomes in Congenital Heart Disease. J Pediatr. 2023 08; 259:113464. View Abstract
22. Computational design of custom therapeutic cells to correct failing human cardiomyocytes. Front Syst Biol. 2023; 3. View Abstract
23. PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell. 2022 04 07; 29(4):559-576.e7. View Abstract
24. In silico Cell Therapy Model Restores Failing Human Myocyte Electrophysiology and Calcium Cycling in Fibrotic Myocardium. Front Physiol. 2021; 12:755881. View Abstract
25. Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Res Ther. 2019 12 04; 10(1):373. View Abstract
26. FTO-Dependent N6-Methyladenosine Regulates Cardiac Function During Remodeling and Repair. Circulation. 2019 01 22; 139(4):518-532. View Abstract
27. Joshua Mayourian: Rising to the Challenge. Circ Res. 2018 05 25; 122(11):1494-1495. View Abstract
28. Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2018 06; 119:147-154. View Abstract
29. Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility. Circ Res. 2018 03 30; 122(7):933-944. View Abstract
30. Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling. Circ Res. 2018 01 05; 122(1):167-183. View Abstract
31. Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies. Methods Mol Biol. 2018; 1816:145-159. View Abstract
32. An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity. Methods Mol Biol. 2018; 1816:17-35. View Abstract
33. Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity. Circ Res. 2017 Aug 04; 121(4):411-423. View Abstract
34. Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes. PLoS Comput Biol. 2016 07; 12(7):e1005014. View Abstract
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