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Research Overview

Dr. Calderon's research focuses on the consequences of prenatal and infant insults to the developing nervous system, particularly in the context of congenital heart disease and/or preterm birth. 

Dr. Calderon's studies include: 

  1. the mechanisms of neurodevelopmental impairments in children and adolescents with critical congenital heart disease after open-heart surgery
  2. the identification of prenatal, neonatal and infant medical risk factors contributing to long-term deficits and 
  3. the study of neurodevelopmental interventions to improve cognitive and behavioral outcomes in this population

Research Background

Dr. Johanna Calderon has a PhD in Pediatric Neuropsychology from Paris Descartes Sorbonne Paris Cite University and a Master's degree in Cognitive Sciences and Psychology from Paris Descartes University.

Publications

  1. Evaluating the factor structure of the Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) in adults with congenital heart disease. Clin Neuropsychol. 2024 Dec 31; 1-12. View Abstract
  2. Neurodevelopmental outcomes of preterm and growth-restricted neonate with congenital heart defect: a systematic review and meta-analysis. Eur J Pediatr. 2024 May; 183(5):1967-1987. View Abstract
  3. Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2023 07 03; 6(7):e2324369. View Abstract
  4. Social cognition and behavioral outcomes in congenital heart disease: profiles and neuropsychiatric comorbidities. Child Neuropsychol. 2023 11; 29(7):1041-1063. View Abstract
  5. Prevalence and associated factors of post-traumatic stress disorder in parents whose infants have single ventricle heart disease. Cardiol Young. 2023 Nov; 33(11):2171-2180. View Abstract
  6. Sleep Patterns in Young Children with Congenital Heart Disease. J Pediatr. 2023 01; 252:198-203.e2. View Abstract
  7. Neurodevelopmental and Mental Health Outcomes in Patients With Fontan Circulation: A State-of-the-Art Review. Front Pediatr. 2022; 10:826349. View Abstract
  8. Fetal Brain Volume Predicts Neurodevelopment in Congenital Heart Disease. Circulation. 2022 04 12; 145(15):1108-1119. View Abstract
  9. Quality of Life of Children Born with a Congenital Heart Defect. J Pediatr. 2022 05; 244:148-153.e5. View Abstract
  10. Neurological features in infants with congenital heart disease. Dev Med Child Neurol. 2022 06; 64(6):762-770. View Abstract
  11. Health-related quality of life and physical activity in children with inherited cardiac arrhythmia or inherited cardiomyopathy: the prospective multicentre controlled QUALIMYORYTHM study rationale, design and methods. Health Qual Life Outcomes. 2021 Jul 28; 19(1):187. View Abstract
  12. Long-Term Neurodevelopmental Outcomes of Children with Congenital Heart Defects. J Pediatr. 2021 Oct; 237:109-114.e5. View Abstract
  13. Neurodevelopmental and psychosocial interventions for individuals with CHD: a research agenda and recommendations from the Cardiac Neurodevelopmental Outcome Collaborative. Cardiol Young. 2021 Jun; 31(6):888-899. View Abstract
  14. Executive functions in children with heart disease: a systematic review and meta-analysis. Cardiol Young. 2021 Dec; 31(12):1914-1922. View Abstract
  15. Randomized Controlled Trial of Working Memory Intervention in Congenital Heart Disease. J Pediatr. 2020 12; 227:191-198.e3. View Abstract
  16. Autism and Congenital Heart Disease: Evidence and Unresolved Questions. Pediatrics. 2019 11; 144(5). View Abstract
  17. Neurotoxicity of general anesthetics in children: evidence and uncertainties. Curr Opin Pediatr. 2019 04; 31(2):267-273. View Abstract
  18. Improving neurodevelopmental outcomes in children with congenital heart disease: protocol for a randomised controlled trial of working memory training. BMJ Open. 2019 02 19; 9(2):e023304. View Abstract
  19. Outcomes Research in Vulnerable Pediatric Populations. J Neurosurg Anesthesiol. 2019 Jan; 31(1):140-143. View Abstract
  20. Working Memory Training: A Promising Intervention? Crit Care Med. 2018 07; 46(7):1199-1201. View Abstract
  21. Neurocognitive and Psychological Outcomes in Adults With Dextro-Transposition of the Great Arteries Corrected by the Arterial Switch Operation. Ann Thorac Surg. 2018 03; 105(3):830-836. View Abstract
  22. Population-based study of cognitive outcomes in congenital heart defects. Arch Dis Child. 2018 01; 103(1):49-56. View Abstract
  23. Cognitive outcomes and health-related quality of life in adults two decades after the arterial switch operation for transposition of the great arteries. J Thorac Cardiovasc Surg. 2017 09; 154(3):1028-1035. View Abstract
  24. Ages and Stages Questionnaire at 3 Years for Predicting IQ at 5-6 Years. Pediatrics. 2017 Apr; 139(4). View Abstract
  25. Neuropsychological and Psychiatric Outcomes in Dextro-Transposition of the Great Arteries across the Lifespan: A State-of-the-Art Review. Front Pediatr. 2017; 5:59. View Abstract
  26. Educational needs of adolescents with congenital heart disease: Impact of a transition intervention programme. Arch Cardiovasc Dis. 2017 May; 110(5):317-324. View Abstract
  27. Psychiatric Disorders in Adolescents With Single Ventricle Congenital Heart Disease. Pediatrics. 2017 Mar; 139(3). View Abstract
  28. Early-Term Birth in Single-Ventricle Congenital Heart Disease After the Fontan Procedure: Neurodevelopmental and Psychiatric Outcomes. J Pediatr. 2016 12; 179:96-103. View Abstract
  29. Executive Function in Patients with Congenital Heart Disease: Only the Tip of the Iceberg? J Pediatr. 2016 06; 173:7-9. View Abstract
  30. Executive function deficits in congenital heart disease: why is intervention important? Cardiol Young. 2015 Oct; 25(7):1238-46. View Abstract
  31. Facial expression recognition and emotion understanding in children after neonatal open-heart surgery for transposition of the great arteries. Dev Med Child Neurol. 2014 Jun; 56(6):564-71. View Abstract
  32. Executive functions development in 5- to 7-year-old children with transposition of the great arteries: a longitudinal study. Dev Neuropsychol. 2014; 39(5):365-84. View Abstract
  33. Use of early remedial services in children with transposition of the great arteries. J Pediatr. 2013 Oct; 163(4):1105-10.e1. View Abstract
  34. Impact of prenatal diagnosis on neurocognitive outcomes in children with transposition of the great arteries. J Pediatr. 2012 Jul; 161(1):94-8.e1. View Abstract
  35. Executive function and theory of mind in school-aged children after neonatal corrective cardiac surgery for transposition of the great arteries. Dev Med Child Neurol. 2010 Dec; 52(12):1139-44. View Abstract

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