With over 15 years of experience, he specializes in machine learning, statistics, and image/signal analysis, focusing on interdisciplinary biomedical applications:
Publications
Using Implementation Science to Assess Barriers to Agreement on Sedation Goal Setting and Assessment. Pediatr Crit Care Med. 2025 Jan 01; 26(1):e51-e61. View Abstract
Epidemiology and Regional Variation in Additional Surgical Interventions for Children with Congenital Diaphragmatic Hernia: A Multi-institutional Analysis. Ann Surg. 2024 Sep 17. View Abstract
Discovering the effective connectome of the brain with dynamic Bayesian DAG learning. Neuroimage. 2024 Aug 15; 297:120684. View Abstract
Using the Past to Inform the Future: How a Classic Respiratory Physiology Equation Informs Computer-Based Simulators and Clinical Decision Support Systems. Pediatr Crit Care Med. 2024 May 01; 25(5):466-468. View Abstract
Changes in Global Nutrition Practices in Critically Ill Children and the Influence of Emerging Evidence: A Secondary Analysis of the Pediatric International Nutrition Studies, 2009-2018. J Acad Nutr Diet. 2024 Dec; 124(12):1657-1667.e5. View Abstract
Measurement Error. Pediatr Crit Care Med. 2024 Mar 01; 25(3):e140-e148. View Abstract
Comparing the Quality of Domain-Specific Versus General Language Models for Artificial Intelligence-Generated Differential Diagnoses in PICU Patients. Pediatr Crit Care Med. 2024 Jun 01; 25(6):e273-e282. View Abstract
Automated Calculator for the Pediatric Sequential Organ Failure Assessment Score: Development and External Validation in a Single-Center 7-Year Cohort, 2015-2021. Pediatr Crit Care Med. 2024 May 01; 25(5):434-442. View Abstract
Dynamic Prediction of Mortality Using Longitudinally Measured Pediatric Sequential Organ Failure Assessment Scores: A Joint Modeling Approach. Pediatr Crit Care Med. 2024 May 01; 25(5):443-451. View Abstract
Brain effective connectome based on fMRI and DTI data: Bayesian causal learning and assessment. PLoS One. 2023; 18(8):e0289406. View Abstract
Heart Rate Change as a Potential Digital Biomarker of Brain Death in Critically Ill Children With Acute Catastrophic Brain Injury. Crit Care Explor. 2023 May; 5(5):e0908. View Abstract
Long-Term Functional Outcomes at 1-Year After Hospital Discharge in Critically Ill Neonates With Congenital Diaphragmatic Hernia. Pediatr Crit Care Med. 2023 08 01; 24(8):e372-e381. View Abstract
Validation and Extension of the Association Between Potentially Excess Oxygen Exposure and Death in Mechanically Ventilated Children. Pediatr Crit Care Med. 2023 09 01; 24(9):e434-e440. View Abstract
Impact of implementing an evidence-based definition of enteral nutrition intolerance on nutrition delivery: A prospective, cross-sectional cohort study. Nutr Clin Pract. 2023 Apr; 38(2):376-385. View Abstract
Pharmacokinetic Modeling of Optimized Midazolam and Pentobarbital Dosing Used in Treatment Protocols of Refractory Status Epilepticus. Pediatr Crit Care Med. 2023 01 01; 24(1):51-55. View Abstract
Factors Associated With Mechanical Ventilation Duration in Pediatric Burn Patients in a Regional Burn Center in the United States. Pediatr Crit Care Med. 2022 11 01; 23(11):e536-e540. View Abstract
Optic Nerve Sheath Viscoelastic Properties: Re-Examination of Biomechanical Behavior and Clinical Implications. Neurocrit Care. 2022 08; 37(1):184-189. View Abstract
Artificial Neural Network Algorithms to Predict Resting Energy Expenditure in Critically Ill Children. Nutrients. 2021 Oct 26; 13(11). View Abstract
Implementation of an Analgesia-Sedation Protocol Is Associated With Reduction in Midazolam Usage in the PICU. Pediatr Crit Care Med. 2021 10 01; 22(10):e513-e523. View Abstract
Sporadic and Periodic Interictal Discharges in Critically Ill Children: Seizure Associations and Time to Seizure Identification. J Clin Neurophysiol. 2023 Feb 01; 40(2):130-135. View Abstract
A Machine Learning Classifier Improves Mortality Prediction Compared With Pediatric Logistic Organ Dysfunction-2 Score: Model Development and Validation. Crit Care Explor. 2021 May; 3(5):e0426. View Abstract
EEG features of brain injury during extracorporeal membrane oxygenation in children. Neurology. 2020 09 08; 95(10):e1372-e1380. View Abstract
Meaning of Intracranial Pressure-to-Blood Pressure Fisher-Transformed Pearson Correlation-Derived Optimal Cerebral Perfusion Pressure: Testing Empiric Utility in a Mechanistic Model. Crit Care Med. 2018 12; 46(12):e1160-e1166. View Abstract
Reproducibility of Brain MRI Segmentation Algorithms: Empirical Comparison of Local MAP PSTAPLE, FreeSurfer, and FSL-FIRST. J Neuroimaging. 2018 03; 28(2):162-172. View Abstract
Updating Evidence for Using Therapeutic Hypothermia in Pediatric Severe Traumatic Brain Injury. Crit Care Med. 2017 10; 45(10):e1091. View Abstract
Updating Evidence for Using Hypothermia in Pediatric Severe Traumatic Brain Injury: Conventional and Bayesian Meta-Analytic Perspectives. Pediatr Crit Care Med. 2017 Apr; 18(4):355-362. View Abstract
Both 3-T dGEMRIC and Acetabular-Femoral T2 Difference May Detect Cartilage Damage at the Chondrolabral Junction. Clin Orthop Relat Res. 2017 Apr; 475(4):1058-1065. View Abstract
A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth. Sci Rep. 2017 03 28; 7(1):476. View Abstract
Reduced thalamic volume in patients with Electrical Status Epilepticus in Sleep. Epilepsy Res. 2017 02; 130:74-80. View Abstract
White Matter Volume Predicts Language Development in Congenital Heart Disease. J Pediatr. 2017 02; 181:42-48.e2. View Abstract
Targeted Temperature Management After Cardiac Arrest Due to Drowning: "Frequentist" and "Bayesian" Decision Making. Pediatr Crit Care Med. 2016 08; 17(8):789-91. View Abstract
Fast myelin water fraction estimation using 2D multislice CPMG. Magn Reson Med. 2016 10; 76(4):1301-13. View Abstract
Optimal MAP Parameters Estimation in STAPLE Using Local Intensity Similarity Information. IEEE J Biomed Health Inform. 2015 Sep; 19(5):1589-97. View Abstract
Three-dimensional hip cartilage quality assessment of morphology and dGEMRIC by planar maps and automated segmentation. Osteoarthritis Cartilage. 2014 Oct; 22(10):1511-5. View Abstract
A logarithmic opinion pool based STAPLE algorithm for the fusion of segmentations with associated reliability weights. IEEE Trans Med Imaging. 2014 Oct; 33(10):1997-2009. View Abstract
Lateralization of temporal lobe epilepsy using a novel uncertainty analysis of MR diffusion in hippocampus, cingulum, and fornix, and hippocampal volume and FLAIR intensity. J Neurol Sci. 2014 Jul 15; 342(1-2):152-61. View Abstract
T(2)-relaxometry for myelin water fraction extraction using wald distribution and extended phase graph. Med Image Comput Comput Assist Interv. 2014; 17(Pt 3):145-52. View Abstract
Construction of a deformable spatiotemporal MRI atlas of the fetal brain: evaluation of similarity metrics and deformation models. Med Image Comput Comput Assist Interv. 2014; 17(Pt 2):292-9. View Abstract
Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. Int J Comput Assist Radiol Surg. 2014 Jan; 9(1):91-105. View Abstract
Simultaneous truth and performance level estimation through fusion of probabilistic segmentations. IEEE Trans Med Imaging. 2013 Oct; 32(10):1840-52. View Abstract
Characterizing the distribution of anisotropic micro-structural environments with diffusion-weighted imaging (DIAMOND). Med Image Comput Comput Assist Interv. 2013; 16(Pt 3):518-26. View Abstract
Estimating a reference standard segmentation with spatially varying performance parameters: local MAP STAPLE. IEEE Trans Med Imaging. 2012 Aug; 31(8):1593-606. View Abstract
WHOLE BRAIN GROUP NETWORK ANALYSIS USING NETWORK BIAS AND VARIANCE PARAMETERS. Proc IEEE Int Symp Biomed Imaging. 2012 May; 2012:1511-1514. View Abstract
Multi-atlas multi-shape segmentation of fetal brain MRI for volumetric and morphometric analysis of ventriculomegaly. Neuroimage. 2012 Apr 15; 60(3):1819-31. View Abstract
Estimation of the prior distribution of ground truth in the STAPLE algorithm: an empirical Bayesian approach. Med Image Comput Comput Assist Interv. 2012; 15(Pt 1):593-600. View Abstract
Two-stage multishape segmentation of brain structures using image intensity, tissue type, and location information. Med Phys. 2010 Aug; 37(8):4501-16. View Abstract
Two-stage multishape segmentation of brain structures using image intensity, tissue type, and location informationa). Med Phys. 2010 Aug; 37(8):4501-4516. View Abstract
Web-based interactive 2D/3D medical image processing and visualization software. Comput Methods Programs Biomed. 2010 May; 98(2):172-82. View Abstract
Hippocampal volumetry for lateralization of temporal lobe epilepsy: automated versus manual methods. Neuroimage. 2011 Jan; 54 Suppl 1:S218-26. View Abstract
Three-dimensional coupled-object segmentation using symmetry and tissue type information. Comput Med Imaging Graph. 2010 Apr; 34(3):236-49. View Abstract