Research Background

With over 15 years of experience, he specializes in machine learning, statistics, and image/signal analysis, focusing on interdisciplinary biomedical applications:

Publications

  1. Bowel regimen medication use and its effect on bowel movements in a pediatric intensive care unit: A retrospective study. Nutr Clin Pract. 2025 May 02. View Abstract
  2. Using Implementation Science to Assess Barriers to Agreement on Sedation Goal Setting and Assessment. Pediatr Crit Care Med. 2025 Jan 01; 26(1):e51-e61. View Abstract
  3. Epidemiology and Regional Variation in Additional Surgical Interventions for Children with Congenital Diaphragmatic Hernia: A Multi-institutional Analysis. Ann Surg. 2024 Sep 17. View Abstract
  4. Discovering the effective connectome of the brain with dynamic Bayesian DAG learning. Neuroimage. 2024 Aug 15; 297:120684. View Abstract
  5. Using the Past to Inform the Future: How a Classic Respiratory Physiology Equation Informs Computer-Based Simulators and Clinical Decision Support Systems. Pediatr Crit Care Med. 2024 May 01; 25(5):466-468. View Abstract
  6. Changes in Global Nutrition Practices in Critically Ill Children and the Influence of Emerging Evidence: A Secondary Analysis of the Pediatric International Nutrition Studies, 2009-2018. J Acad Nutr Diet. 2024 Dec; 124(12):1657-1667.e5. View Abstract
  7. Measurement Error. Pediatr Crit Care Med. 2024 Mar 01; 25(3):e140-e148. View Abstract
  8. Comparing the Quality of Domain-Specific Versus General Language Models for Artificial Intelligence-Generated Differential Diagnoses in PICU Patients. Pediatr Crit Care Med. 2024 Jun 01; 25(6):e273-e282. View Abstract
  9. Automated Calculator for the Pediatric Sequential Organ Failure Assessment Score: Development and External Validation in a Single-Center 7-Year Cohort, 2015-2021. Pediatr Crit Care Med. 2024 May 01; 25(5):434-442. View Abstract
  10. Dynamic Prediction of Mortality Using Longitudinally Measured Pediatric Sequential Organ Failure Assessment Scores: A Joint Modeling Approach. Pediatr Crit Care Med. 2024 May 01; 25(5):443-451. View Abstract
  11. Brain effective connectome based on fMRI and DTI data: Bayesian causal learning and assessment. PLoS One. 2023; 18(8):e0289406. View Abstract
  12. Heart Rate Change as a Potential Digital Biomarker of Brain Death in Critically Ill Children With Acute Catastrophic Brain Injury. Crit Care Explor. 2023 May; 5(5):e0908. View Abstract
  13. Long-Term Functional Outcomes at 1-Year After Hospital Discharge in Critically Ill Neonates With Congenital Diaphragmatic Hernia. Pediatr Crit Care Med. 2023 08 01; 24(8):e372-e381. View Abstract
  14. Validation and Extension of the Association Between Potentially Excess Oxygen Exposure and Death in Mechanically Ventilated Children. Pediatr Crit Care Med. 2023 09 01; 24(9):e434-e440. View Abstract
  15. Impact of implementing an evidence-based definition of enteral nutrition intolerance on nutrition delivery: A prospective, cross-sectional cohort study. Nutr Clin Pract. 2023 Apr; 38(2):376-385. View Abstract
  16. Pharmacokinetic Modeling of Optimized Midazolam and Pentobarbital Dosing Used in Treatment Protocols of Refractory Status Epilepticus. Pediatr Crit Care Med. 2023 01 01; 24(1):51-55. View Abstract
  17. Factors Associated With Mechanical Ventilation Duration in Pediatric Burn Patients in a Regional Burn Center in the United States. Pediatr Crit Care Med. 2022 11 01; 23(11):e536-e540. View Abstract
  18. Optic Nerve Sheath Viscoelastic Properties: Re-Examination of Biomechanical Behavior and Clinical Implications. Neurocrit Care. 2022 08; 37(1):184-189. View Abstract
  19. Artificial Neural Network Algorithms to Predict Resting Energy Expenditure in Critically Ill Children. Nutrients. 2021 Oct 26; 13(11). View Abstract
  20. Implementation of an Analgesia-Sedation Protocol Is Associated With Reduction in Midazolam Usage in the PICU. Pediatr Crit Care Med. 2021 10 01; 22(10):e513-e523. View Abstract
  21. Sporadic and Periodic Interictal Discharges in Critically Ill Children: Seizure Associations and Time to Seizure Identification. J Clin Neurophysiol. 2023 Feb 01; 40(2):130-135. View Abstract
  22. A Machine Learning Classifier Improves Mortality Prediction Compared With Pediatric Logistic Organ Dysfunction-2 Score: Model Development and Validation. Crit Care Explor. 2021 May; 3(5):e0426. View Abstract
  23. EEG features of brain injury during extracorporeal membrane oxygenation in children. Neurology. 2020 09 08; 95(10):e1372-e1380. View Abstract
  24. Meaning of Intracranial Pressure-to-Blood Pressure Fisher-Transformed Pearson Correlation-Derived Optimal Cerebral Perfusion Pressure: Testing Empiric Utility in a Mechanistic Model. Crit Care Med. 2018 12; 46(12):e1160-e1166. View Abstract
  25. Reproducibility of Brain MRI Segmentation Algorithms: Empirical Comparison of Local MAP PSTAPLE, FreeSurfer, and FSL-FIRST. J Neuroimaging. 2018 03; 28(2):162-172. View Abstract
  26. Updating Evidence for Using Therapeutic Hypothermia in Pediatric Severe Traumatic Brain Injury. Crit Care Med. 2017 10; 45(10):e1091. View Abstract
  27. Updating Evidence for Using Hypothermia in Pediatric Severe Traumatic Brain Injury: Conventional and Bayesian Meta-Analytic Perspectives. Pediatr Crit Care Med. 2017 Apr; 18(4):355-362. View Abstract
  28. Both 3-T dGEMRIC and Acetabular-Femoral T2 Difference May Detect Cartilage Damage at the Chondrolabral Junction. Clin Orthop Relat Res. 2017 Apr; 475(4):1058-1065. View Abstract
  29. A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth. Sci Rep. 2017 03 28; 7(1):476. View Abstract
  30. Reduced thalamic volume in patients with Electrical Status Epilepticus in Sleep. Epilepsy Res. 2017 02; 130:74-80. View Abstract
  31. White Matter Volume Predicts Language Development in Congenital Heart Disease. J Pediatr. 2017 02; 181:42-48.e2. View Abstract
  32. Targeted Temperature Management After Cardiac Arrest Due to Drowning: "Frequentist" and "Bayesian" Decision Making. Pediatr Crit Care Med. 2016 08; 17(8):789-91. View Abstract
  33. Fast myelin water fraction estimation using 2D multislice CPMG. Magn Reson Med. 2016 10; 76(4):1301-13. View Abstract
  34. Optimal MAP Parameters Estimation in STAPLE Using Local Intensity Similarity Information. IEEE J Biomed Health Inform. 2015 Sep; 19(5):1589-97. View Abstract
  35. Three-dimensional hip cartilage quality assessment of morphology and dGEMRIC by planar maps and automated segmentation. Osteoarthritis Cartilage. 2014 Oct; 22(10):1511-5. View Abstract
  36. A logarithmic opinion pool based STAPLE algorithm for the fusion of segmentations with associated reliability weights. IEEE Trans Med Imaging. 2014 Oct; 33(10):1997-2009. View Abstract
  37. Lateralization of temporal lobe epilepsy using a novel uncertainty analysis of MR diffusion in hippocampus, cingulum, and fornix, and hippocampal volume and FLAIR intensity. J Neurol Sci. 2014 Jul 15; 342(1-2):152-61. View Abstract
  38. T(2)-relaxometry for myelin water fraction extraction using wald distribution and extended phase graph. Med Image Comput Comput Assist Interv. 2014; 17(Pt 3):145-52. View Abstract
  39. Construction of a deformable spatiotemporal MRI atlas of the fetal brain: evaluation of similarity metrics and deformation models. Med Image Comput Comput Assist Interv. 2014; 17(Pt 2):292-9. View Abstract
  40. Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. Int J Comput Assist Radiol Surg. 2014 Jan; 9(1):91-105. View Abstract
  41. Simultaneous truth and performance level estimation through fusion of probabilistic segmentations. IEEE Trans Med Imaging. 2013 Oct; 32(10):1840-52. View Abstract
  42. Characterizing the distribution of anisotropic micro-structural environments with diffusion-weighted imaging (DIAMOND). Med Image Comput Comput Assist Interv. 2013; 16(Pt 3):518-26. View Abstract
  43. Estimating a reference standard segmentation with spatially varying performance parameters: local MAP STAPLE. IEEE Trans Med Imaging. 2012 Aug; 31(8):1593-606. View Abstract
  44. WHOLE BRAIN GROUP NETWORK ANALYSIS USING NETWORK BIAS AND VARIANCE PARAMETERS. Proc IEEE Int Symp Biomed Imaging. 2012 May; 2012:1511-1514. View Abstract
  45. Multi-atlas multi-shape segmentation of fetal brain MRI for volumetric and morphometric analysis of ventriculomegaly. Neuroimage. 2012 Apr 15; 60(3):1819-31. View Abstract
  46. Estimation of the prior distribution of ground truth in the STAPLE algorithm: an empirical Bayesian approach. Med Image Comput Comput Assist Interv. 2012; 15(Pt 1):593-600. View Abstract
  47. Two-stage multishape segmentation of brain structures using image intensity, tissue type, and location information. Med Phys. 2010 Aug; 37(8):4501-16. View Abstract
  48. Two-stage multishape segmentation of brain structures using image intensity, tissue type, and location informationa). Med Phys. 2010 Aug; 37(8):4501-4516. View Abstract
  49. Web-based interactive 2D/3D medical image processing and visualization software. Comput Methods Programs Biomed. 2010 May; 98(2):172-82. View Abstract
  50. Hippocampal volumetry for lateralization of temporal lobe epilepsy: automated versus manual methods. Neuroimage. 2011 Jan; 54 Suppl 1:S218-26. View Abstract
  51. Three-dimensional coupled-object segmentation using symmetry and tissue type information. Comput Med Imaging Graph. 2010 Apr; 34(3):236-49. View Abstract

Contact Alireza Akhondi-Asl