Can your child participate?

If your child is <17 years, is on ECMO using the Cardiohelp system, and is being cared for by one of the participating institutions, your child may be eligible to participate in TROLLEY. A member of your local study team will reach out to you to discuss your child’s participation in the study if they are eligible.

What will happen in this research study?

This study lasts 18 months. As part of the study, most participants will be randomly assigned to receive the blood thinner heparin or bivalirudin. We will gather information from participants’ medical records to see how they are doing. We will assess participants daily for 30 days after they first receive ECMO, or until they are removed from ECMO. We will also assess participants at the time of hospital discharge. Finally, a participant may have one additional clinical visit at approximately 12-18 months after ECMO for neurodevelopmental measurement.

Will your privacy be protected?

We take confidentiality very seriously and will ensure that your right to privacy is protected. Participation in this research study will remain confidential. No names or other identifying information will be used in any published report of information from this study.

Is there any cost to participate?

Tests that are done for research that are not part of regular care will be provided free of charge. Participants and families will be compensated for time and effort.

Is it possible to leave the study early?

Yes. It is up to the child's family to decide to be in the study. Once in, you may leave the study at any time. Being in the study, or choosing to leave the study, will not affect other medical care at any time. 

How long will you be in the study?

Participants are followed for 12 -18 months after enrollment. 

Will the results of the study be shared?

We plan to publish what we find out from the study so we can share this important information with families, researchers, and healthcare providers. Publications will be announced on this website and communicated through study sites.