The Pain and Affective Neuroscience (PAN) Center is co-directed by Dr. Scott Holmes and Dr. Eric Moulton. This translational and interdisciplinary research center will be comprised of the labs of Drs. Holmes and Moulton with the central goal of elucidating the biobehavioral and neural mechanisms contributing to the acute to chronic pain transition, as well as treatment response in patients with chronic pain. The PAN Center will promote the sharing of resources to support the pursuit of novel research investigations among participating investigators. Participating labs will join in monthly lab meetings to promote trainee development and collaboration amongst investigators. Additionally, a goal of the PAN Center will be to bridge the gap between pain clinicians and pain scientists in the Department by fostering research collaboration and mentoring.

Composite Labs

Brain and Eye Pain Imaging Lab

Director: Dr. Moulton

The Brain and Eye Pain Imaging Lab (BEPI Lab) investigates nociceptive processing in the human central nervous system, particularly as it relates to oculofacial pain and related disorders. We combine functional and structural neuroimaging techniques, including functional MRI and corneal microscopy, to address translational topics related to pain in patients and volunteers.

Pediatric Pain Pathway Lab

Director: Dr. Holmes

The focus of the Pediatric Pain Pathway Lab (P3 Lab) is to explore how pain interferes with sensorimotor integration and translates into behavioral disabilities. We investigate the independent role of peripheral and central contributions to understanding and treating pain in pediatric subjects. We emphasize the role of the human motor system as a non-pharmacological source of pain medicine to address pain symptoms through self-directed and neuromodulatory approaches to improve patient agency and mental health.

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