Overview

The research program within Boston Children's Hospital's Division of Nephrology conducts both basic and clinical research in transplantation biology, kidney development, nephrotic syndrome, and autosomal recessive polycystic disease of the kidney. The heads of our key laboratories also hold faculty appointments at Harvard Medical School.

Recognizing that more than half of children with kidney failure have developmental anomalies, the division has assembled a very large developmental and regenerative biology team. We also have created a pharmacogenomics group to take advantage of the remarkable breakthroughs of modern genomics and customize treatments to each child.

Current research projects

  • Genetic testing for nephrotic syndrome and FSGS
  • Understanding kidney self-repair
  • Improving outcomes following kidney transplantation
  • Kidney stone genetics and prevention
  • Using applied genomics to treat nephrotic syndrome
  • Gene regulation and kidney disease
  • Genetic basis of pediatric kidney disease
  • Clinical relevance of ABCB5