Most recent 100 publications Intestinal injury and repair: insights from hyaline fibromatosis syndrome; Aug 23, 2025; pubmed:40847215. View Intestinal injury and repair: insights from hyaline fibromatosis syndrome on PubMed The Genetic Architecture of Congenital Diarrhea and Enteropathy; Apr 2, 2025; pubmed:40174224. View The Genetic Architecture of Congenital Diarrhea and Enteropathy on PubMed Sorting of complex sphingolipids within the cellular endomembrane systems; Mar 13, 2025; pubmed:40078962. View Sorting of complex sphingolipids within the cellular endomembrane systems on PubMed SLO co-opts host cell glycosphingolipids to access cholesterol-rich lipid rafts for enhanced pore formation and cytotoxicity; Jan 21, 2025; pubmed:39835825. View SLO co-opts host cell glycosphingolipids to access cholesterol-rich lipid rafts for enhanced pore formation and cytotoxicity on PubMed Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production; May 4, 2024; pubmed:38704148. View Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production on PubMed IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response; Apr 5, 2024; pubmed:38578285. View IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response on PubMed Protocol for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal organoids; May 27, 2023; pubmed:37243601. View Protocol for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal organoids on PubMed Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking; Jul 13, 2022; pubmed:35830800. View Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking on PubMed The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development; Jun 21, 2022; pubmed:35727638. View The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development on PubMed Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces; Feb 10, 2022; pubmed:35143768. View Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces on PubMed Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis; Oct 22, 2021; pubmed:34677124. View Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis on PubMed Cholera Toxin as a Probe for Membrane Biology; Aug 26, 2021; pubmed:34437414. View Cholera Toxin as a Probe for Membrane Biology on PubMed Small-molecule modulators of INAVA cytosolic condensate and cell-cell junction assemblies; Jul 12, 2021; pubmed:34251416. View Small-molecule modulators of INAVA cytosolic condensate and cell-cell junction assemblies on PubMed Ceramide structure dictates glycosphingolipid nanodomain assembly and function; Jun 17, 2021; pubmed:34135326. View Ceramide structure dictates glycosphingolipid nanodomain assembly and function on PubMed Evolution and function of the epithelial cell-specific ER stress sensor IRE1β; Jun 2, 2021; pubmed:34075183. View Evolution and function of the epithelial cell-specific ER stress sensor IRE1β on PubMed A Quantitative Single-cell Flow Cytometry Assay for Retrograde MembraneTrafficking Using Engineered Cholera Toxin; Mar 4, 2021; pubmed:33659371. View A Quantitative Single-cell Flow Cytometry Assay for Retrograde MembraneTrafficking Using Engineered Cholera Toxin on PubMed Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling; Oct 22, 2020; pubmed:33087577. View Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling on PubMed Everything Illuminated-Clostridium perfringens β-toxin; Jul 10, 2020; pubmed:32645353. View Everything Illuminated-Clostridium perfringens β-toxin on PubMed Structured clustering of the glycosphingolipid GM1 is required for membrane curvature induced by cholera toxin; Jun 20, 2020; pubmed:32554490. View Structured clustering of the glycosphingolipid GM1 is required for membrane curvature induced by cholera toxin on PubMed Conjugation of peptides to short-acyl-chain ceramides for delivery across mucosal cell barriers; Feb 22, 2020; pubmed:32081448. View Conjugation of peptides to short-acyl-chain ceramides for delivery across mucosal cell barriers on PubMed IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress; Jan 28, 2020; pubmed:31985747. View IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress on PubMed A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization; Nov 28, 2019; pubmed:31774722. View A quantitative single-cell assay for retrograde membrane traffic enables rapid detection of defects in cellular organization on PubMed A modified cholera toxin B subunit containing an ER retention motif enhances colon epithelial repair <em>via</em> an unfolded protein response; Sep 28, 2019; pubmed:31560862. View A modified cholera toxin B subunit containing an ER retention motif enhances colon epithelial repair <em>via</em> an unfolded protein response on PubMed Transcytosis Assay for Transport of Glycosphingolipids across MDCK-II Cells; Dec 4, 2018; pubmed:30505885. View Transcytosis Assay for Transport of Glycosphingolipids across MDCK-II Cells on PubMed INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling; Oct 26, 2018; pubmed:30355448. View INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling on PubMed CRISPR Screen Reveals that EHEC's T3SS and Shiga Toxin Rely on Shared Host Factors for Infection; Jun 21, 2018; pubmed:29921669. View CRISPR Screen Reveals that EHEC's T3SS and Shiga Toxin Rely on Shared Host Factors for Infection on PubMed Mucosal absorption of therapeutic peptides by harnessing the endogenous sorting of glycosphingolipids; Jun 1, 2018; pubmed:29851380. View Mucosal absorption of therapeutic peptides by harnessing the endogenous sorting of glycosphingolipids on PubMed Advances in Evaluation of Chronic Diarrhea in Infants; Apr 15, 2018; pubmed:29654747. View Advances in Evaluation of Chronic Diarrhea in Infants on PubMed Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling; Apr 13, 2018; pubmed:29649448. View Retraction Notice to: The Unfolded Protein Response Element IRE1α Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling on PubMed Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury; Mar 24, 2017; pubmed:28330995. View Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury on PubMed Membrane Transport across Polarized Epithelia; Feb 19, 2017; pubmed:28213463. View Membrane Transport across Polarized Epithelia on PubMed Opening CFTR in the Intestine: Flushing on Demand; Feb 9, 2017; pubmed:28174716. View Opening CFTR in the Intestine: Flushing on Demand on PubMed A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis; Jan 11, 2017; pubmed:28069747. View A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis on PubMed Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia; Jan 5, 2017; pubmed:28049834. View Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia on PubMed Glycolipid Crosslinking Is Required for Cholera Toxin to Partition Into and Stabilize Ordered Domains; Dec 5, 2016; pubmed:27914621. View Glycolipid Crosslinking Is Required for Cholera Toxin to Partition Into and Stabilize Ordered Domains on PubMed CellMapper: rapid and accurate inference of gene expression in difficult-to-isolate cell types; Oct 1, 2016; pubmed:27687735. View CellMapper: rapid and accurate inference of gene expression in difficult-to-isolate cell types on PubMed Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion; Feb 12, 2016; pubmed:26864627. View Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion on PubMed Electrophysiological Studies into the Safety of the Anti-diarrheal Drug Clotrimazole during Oral Rehydration Therapy; Sep 26, 2015; pubmed:26405813. View Electrophysiological Studies into the Safety of the Anti-diarrheal Drug Clotrimazole during Oral Rehydration Therapy on PubMed Congenital chloride-losing diarrhea in a Mexican child with the novel homozygous SLC26A3 mutation G393W; Jul 10, 2015; pubmed:26157392. View Congenital chloride-losing diarrhea in a Mexican child with the novel homozygous SLC26A3 mutation G393W on PubMed Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway; Jun 22, 2015; pubmed:26093676. View Innate immunity at mucosal surfaces: the IRE1-RIDD-RIG-I pathway on PubMed FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin; May 3, 2015; pubmed:25934922. View FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin on PubMed Microtubule motors power plasma membrane tubulation in clathrin-independent endocytosis; Feb 19, 2015; pubmed:25690058. View Microtubule motors power plasma membrane tubulation in clathrin-independent endocytosis on PubMed 4-Phenylbutyrate attenuates the ER stress response and cyclic AMP accumulation in DYT1 dystonia cell models; Nov 8, 2014; pubmed:25379658. View 4-Phenylbutyrate attenuates the ER stress response and cyclic AMP accumulation in DYT1 dystonia cell models on PubMed Remodeling of the intestinal brush border underlies adhesion and virulence of an enteric pathogen; Aug 21, 2014; pubmed:25139905. View Remodeling of the intestinal brush border underlies adhesion and virulence of an enteric pathogen on PubMed Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation; Jun 21, 2014; pubmed:24949629. View Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation on PubMed Unsaturated glycoceramides as molecular carriers for mucosal drug delivery of GLP-1; Dec 28, 2013; pubmed:24370893. View Unsaturated glycoceramides as molecular carriers for mucosal drug delivery of GLP-1 on PubMed Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer; Dec 3, 2013; pubmed:24290911. View Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer on PubMed Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics; Oct 26, 2013; pubmed:24156398. View Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics on PubMed Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain; Jul 26, 2013; pubmed:23884419. View Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain on PubMed Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules; Jun 7, 2013; pubmed:23741050. View Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules on PubMed The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling; May 21, 2013; pubmed:23684307. View The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling on PubMed A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway; Nov 1, 2012; pubmed:23111873. View A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway on PubMed Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1; Sep 15, 2012; pubmed:22975326. View Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1 on PubMed The immunologic functions of the neonatal Fc receptor for IgG; Sep 6, 2012; pubmed:22948741. View The immunologic functions of the neonatal Fc receptor for IgG on PubMed Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins; Aug 25, 2012; pubmed:22919642. View Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins on PubMed Cross-presentation of IgG-containing immune complexes; Aug 1, 2012; pubmed:22847331. View Cross-presentation of IgG-containing immune complexes on PubMed Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum; Nov 10, 2011; pubmed:22069586. View Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum on PubMed Eliciting mucosal immunity; Oct 14, 2011; pubmed:21992128. View Eliciting mucosal immunity on PubMed Discovery of dual-action membrane-anchored modulators of incretin receptors; Sep 22, 2011; pubmed:21935440. View Discovery of dual-action membrane-anchored modulators of incretin receptors on PubMed To translocate or not: that is the problem; Sep 20, 2011; pubmed:21925105. View To translocate or not: that is the problem on PubMed Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes; Sep 14, 2011; pubmed:21911378. View Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes on PubMed TorsinA participates in endoplasmic reticulum-associated degradation; Jul 14, 2011; pubmed:21750546. View TorsinA participates in endoplasmic reticulum-associated degradation on PubMed Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells; Jun 2, 2011; pubmed:21628593. View Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells on PubMed The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies; Feb 8, 2011; pubmed:21296866. View The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies on PubMed Functional analysis of VopF activity required for colonization in Vibrio cholerae; Dec 15, 2010; pubmed:21151774. View Functional analysis of VopF activity required for colonization in Vibrio cholerae on PubMed Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2; Nov 3, 2010; pubmed:21041954. View Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2 on PubMed Neonatal Fc receptor: from immunity to therapeutics; Oct 2, 2010; pubmed:20886282. View Neonatal Fc receptor: from immunity to therapeutics on PubMed Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cells; Feb 9, 2010; pubmed:20139088. View Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cells on PubMed N-terminal extension of the cholera toxin A1-chain causes rapid degradation after retrotranslocation from endoplasmic reticulum to cytosol; Jan 9, 2010; pubmed:20056601. View N-terminal extension of the cholera toxin A1-chain causes rapid degradation after retrotranslocation from endoplasmic reticulum to cytosol on PubMed An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice; Aug 12, 2009; pubmed:19664634. View An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice on PubMed Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn; Jun 5, 2009; pubmed:19495758. View Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn on PubMed The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity; May 20, 2009; pubmed:19451275. View The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity on PubMed N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG; Jan 24, 2009; pubmed:19164298. View N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG on PubMed Ceramide activates JNK to inhibit a cAMP-gated K+ conductance and Cl- secretion in intestinal epithelia; Sep 30, 2008; pubmed:18820034. View Ceramide activates JNK to inhibit a cAMP-gated K+ conductance and Cl- secretion in intestinal epithelia on PubMed Patching a leaky intestine; Aug 2, 2008; pubmed:18669433. View Patching a leaky intestine on PubMed Dependence of antibody-mediated presentation of antigen on FcRn; Jul 5, 2008; pubmed:18599440. View Dependence of antibody-mediated presentation of antigen on FcRn on PubMed Attenuated endocytosis and toxicity of a mutant cholera toxin with decreased ability to cluster ganglioside GM1 molecules; Jan 24, 2008; pubmed:18212085. View Attenuated endocytosis and toxicity of a mutant cholera toxin with decreased ability to cluster ganglioside GM1 molecules on PubMed Derlin-1 facilitates the retro-translocation of cholera toxin; Dec 21, 2007; pubmed:18094046. View Derlin-1 facilitates the retro-translocation of cholera toxin on PubMed Conversion of apical plasma membrane sphingomyelin to ceramide attenuates the intoxication of host cells by cholera toxin; Dec 7, 2007; pubmed:18052945. View Conversion of apical plasma membrane sphingomyelin to ceramide attenuates the intoxication of host cells by cholera toxin on PubMed Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathway; Nov 16, 2007; pubmed:18003977. View Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathway on PubMed The HA proteins of botulinum toxin disrupt intestinal epithelial intercellular junctions to increase toxin absorption; Sep 18, 2007; pubmed:17868282. View The HA proteins of botulinum toxin disrupt intestinal epithelial intercellular junctions to increase toxin absorption on PubMed Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER; Dec 13, 2006; pubmed:17156122. View Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER on PubMed How the controller is controlled - neonatal Fc receptor expression and immunoglobulin G homeostasis; Dec 5, 2006; pubmed:17140402. View How the controller is controlled - neonatal Fc receptor expression and immunoglobulin G homeostasis on PubMed IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunity; Oct 20, 2006; pubmed:17051393. View IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunity on PubMed Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria; Jul 15, 2006; pubmed:16841095. View Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria on PubMed A biochemical method for tracking cholera toxin transport from plasma membrane to Golgi and endoplasmic reticulum; Jun 27, 2006; pubmed:16799195. View A biochemical method for tracking cholera toxin transport from plasma membrane to Golgi and endoplasmic reticulum on PubMed Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation; Jun 21, 2006; pubmed:16785320. View Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation on PubMed The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells; May 9, 2006; pubmed:16677615. View The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells on PubMed Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure; Apr 28, 2006; pubmed:16638813. View Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure on PubMed Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane: co-opting basic mechanisms of endoplasmic reticulum-associated degradation; Apr 1, 2006; pubmed:16573240. View Entry of protein toxins into mammalian cells by crossing the endoplasmic reticulum membrane: co-opting basic mechanisms of endoplasmic reticulum-associated degradation on PubMed The viral E3 ubiquitin ligase mK3 uses the Derlin/p97 endoplasmic reticulum-associated degradation pathway to mediate down-regulation of major histocompatibility complex class I proteins; Feb 1, 2006; pubmed:16446359. View The viral E3 ubiquitin ligase mK3 uses the Derlin/p97 endoplasmic reticulum-associated degradation pathway to mediate down-regulation of major histocompatibility complex class I proteins on PubMed Antibodies in the breakdown lane; Oct 8, 2005; pubmed:16211062. View Antibodies in the breakdown lane on PubMed Raft trafficking of AB5 subunit bacterial toxins; Sep 13, 2005; pubmed:16153723. View Raft trafficking of AB5 subunit bacterial toxins on PubMed Calnexin and ERp57 facilitate the assembly of the neonatal Fc receptor for IgG with beta 2-microglobulin in the endoplasmic reticulum; Jul 9, 2005; pubmed:16002696. View Calnexin and ERp57 facilitate the assembly of the neonatal Fc receptor for IgG with beta 2-microglobulin in the endoplasmic reticulum on PubMed Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate; Jun 4, 2005; pubmed:15932873. View Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate on PubMed Signal transduction by bacterial proteins; Apr 5, 2005; pubmed:15805843. View Signal transduction by bacterial proteins on PubMed Characterization of the porcine neonatal Fc receptor--potential use for trans-epithelial protein delivery; Apr 5, 2005; pubmed:15804291. View Characterization of the porcine neonatal Fc receptor--potential use for trans-epithelial protein delivery on PubMed Endocytosis of cholera toxin by human enterocytes is developmentally regulated; Mar 26, 2005; pubmed:15790757. View Endocytosis of cholera toxin by human enterocytes is developmentally regulated on PubMed A passionate kiss, then run: exocytosis and recycling of IgG by FcRn; Jan 18, 2005; pubmed:15653072. View A passionate kiss, then run: exocytosis and recycling of IgG by FcRn on PubMed Ganglioside GD1a restores infectibility to mouse cells lacking functional receptors for polyomavirus; Dec 15, 2004; pubmed:15596855. View Ganglioside GD1a restores infectibility to mouse cells lacking functional receptors for polyomavirus on PubMed Show All Publications Show Fewer Publications Full list of Dr. Lencer's publications