Every child with ADHD is different. Their care should be too.

ADHD is one of the most common conditions of childhood: about 1 in 9 children in the U.S. has been diagnosed. But two children with the same diagnosis can look completely different. They have different strengths, different struggles, and different responses to the same treatment.

At the Arnett Lab, we study how children's brains, genes, and everyday lives shape ADHD. Our goal is to move toward a future where ADHD care is more precise, more personalized, and better suited to each child's unique needs.

 

Three girls and two boys huddled together smiling

What we're working toward

Understanding what makes each child unique

ADHD is not the same for every child. We investigate whether differences in brain activity, genetics, problem solving, and behavior can explain why children experience ADHD in different ways. Understanding this variation is an important step toward developing care that better reflects each child's needs.

Catch ADHD earlier

ADHD often isn't diagnosed until age 7 or later, after a child may already have struggled in school and with friends. We look for early signs in babies' brain activity, toddlers' development, and family genetics that could help families and pediatricians act sooner.

Find the right care for each child

Both behavioral interventions and medications can support children with ADHD to be their best selves, but the best therapy for one child may not be the best for all. We measure brain activity with EEG, a safe and painless test using a soft cap of sensors, and study genetics to find clues that could one day help clinicians choose the best treatment for each child.

Bring new tools into everyday pediatric care

Most families first raise concerns with their pediatrician rather than a specialist. Our newest studies test whether brain and genetic testing can work smoothly in community clinics, so these tools reach families where they already receive care.

Support the whole family

ADHD affects the whole household. We study what helps families day to day, from managing screen time to understanding how families in different communities think about ADHD and what gets in the way of getting help.

What we've learned

52%

Genes may explain more ADHD than anyone expected

Scientists long assumed ADHD was too genetically complex to diagnose with a gene test. In a pilot study of 77 children, Dr. Arnett and Dr. Ryan Doan found genetic changes likely to contribute to ADHD in about half of families (JAMA Pediatrics, 2023). 

Read the story.

ADHD and anxiety can look alike, but the brain can tell them apart

Children with ADHD and children with anxiety can both have trouble paying attention. Our EEG research found that the brain processes behind that inattention overlap in some ways and differ in others, a step toward more accurate diagnosis (Journal of Attention Disorders, 2026).

Self-control skills may protect kids at risk

In a large national study, children with stronger self-control skills were less likely to develop ADHD symptoms, even when ADHD ran in their family (Research on Child and Adolescent Psychopathology, 2024).

Get involved

We are deeply grateful to the families who make this work possible. Whether through participation in laboratory studies, piloting new interventions, completing interviews, or simply spreading the word about our work, their contributions help us better understand ADHD and the many ways children develop.

For families

Join a study

Our Genomics Study is enrolling children with ADHD now, and you can take part entirely from home. It starts with a 30-minute phone call; then we mail a saliva and cheek-swab kit with a prepaid return label. Families receive $25. 

See our current studies.

For everyone

Learn with us

Watch Answers Through Research, our video series where Drs. Arnett and Peisch turn ADHD research into everyday tips. You'll also find free Boston Children's ADHD guides for parents of preschoolers through middle schoolers, and our seasonal newsletter.

Explore resources for families.

Meet Dr. Arnett

Anne Arnett

Anne B. Arnett, PhD, is a clinical psychologist and Scientist in the Division of Developmental Medicine at Boston Children's Hospital, where she is the Wade Family Investigator in Child Psychology. She is also an Assistant Professor of Pediatrics at Harvard Medical School. Her team is part of the Laboratories of Cognitive Neuroscience.

Meet our team. Learn about our team and the scientists working to better understand childhood ADHD.

Get in touch

Questions about our research or interested in learning more? Email ArnettLab@childrens.harvard.edu or call 617-919-7772.