Information

Related Research Units

Fetal Neonatal Neuroimaging and Developmental Science Center Research
Neurology Research
Radiology Research
Newborn Medicine Research
Computational Health Informatics Program Research

Research Overview

Dr. Yangming Ou's research focuses on improving healthcare by medical image analysis, machine learning and imaging informatics.

One pillar of Dr. Ou's lab is in developing MRI analysis and MRI machine learning algorithms. This includes algorithms for spatiotemporal MRI analysis, multi-modal MRI integration, quantification of normal brain development, detection of abnormalities, prediction of outcomes, treatment evaluation, and disease subtyping.

Another pillar of Dr. Ou's lab is in applying advanced imaging informatics for clinical studies. The topics span mild, moderate and severe brain abnormalities. Mild conditions studied in the lab includes nutrition insufficiency and kids with in-utero exposure to opioid. Moderate conditions include hypoxic ischemic injury, rare diseases such as Sturge-Weber Syndrom, early screening of psychosis, dyslexia, etc. Severe diesease include pediatric brain tumor and how to improve neurocognitive outcomes in survivors.

Research Background

Dr. Ou holds a PhD degree in Medical Image Analysis and an MS degree in Applied Mathematics, both from the University of Pennsylvania. His BS degree was in Electrical Engineering (Biomedical Engineering Division) from Tsinghua University. His research interest lies in the intersection of big data, machine learning, data science, imaging informatics, and healthcare.

 

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Can we prevent seizures in Sturge-Weber syndrome?

Publications

  1. Machine learning to infer neurocognitive testing scores among adolescents and young adults with congenital heart disease. Commun Med (Lond). 2026 Feb 06; 6(1). View Abstract
  2. BONBID-HIE 2023: Lesion Segmentation Challenge in BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy. IEEE Trans Med Imaging. 2025 Dec 11; PP. View Abstract
  3. The 2024 report of the synergetic roadmap on carbon neutrality and clean air for China: Pollution and carbon reduction promote green economic development. Environ Sci Ecotechnol. 2025 Nov; 28:100636. View Abstract
  4. Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Diabetic Neuropathic Pain via TRPV1-[Ca2+]i-AMPK Signaling-Mediated Mitochondrial Restoration in Schwann Cells. Stem Cells Int. 2025; 2025:5533136. View Abstract
  5. Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer. Adv Sci (Weinh). 2026 Jan; 13(4):e10307. View Abstract
  6. Asymmetric Electrosorption in a Bio-Inspired Reactor Enables Energy Efficient Ocean Carbon Removal. Angew Chem Int Ed Engl. 2025 Dec 01; 64(49):e202515007. View Abstract
  7. Maternal Childhood Neglect is Linked to Greater Infant Cortisol Levels and Larger Infant Limbic Volumes. Child Maltreat. 2025 Sep 15; 10775595251376623. View Abstract
  8. Data harmonization framework for neonatal hypoxic-ischemic encephalopathy studies. JAMIA Open. 2025 Oct; 8(5):ooaf086. View Abstract
  9. Oxidative stress-induced ZEB1 acetylation drives a hybrid epithelial-mesenchymal phenotype and promotes lung metastasis in triple-negative breast cancer. Redox Biol. 2025 10; 86:103834. View Abstract
  10. CK2 kinase-PRC2 signalling regulates genome-wide H3K27 trimethylation and transduces prolonged cold exposure into epigenetic cold memory in plants. Nat Plants. 2025 08; 11(8):1572-1590. View Abstract
  11. Adipocyte-specific Zeb1 downregulation remodels the tumor-associated adipose microenvironment to facilitate female breast cancer progression. Nat Commun. 2025 Jul 01; 16(1):6011. View Abstract
  12. Genetic mechanisms, brain structures, and peripheral biomarkers mediate the relationship between physical frailty and neuropsychiatric disorders. J Adv Res. 2026 Apr; 82:685-699. View Abstract
  13. Associations of early-life factors and risks of incident dementia: A cohort study of 247,841 participants. J Affect Disord. 2025 Nov 15; 389:119669. View Abstract
  14. RGIs-mediated root apical meristem development is essential for root hydrotropic response in Arabidopsis thaliana. Plant J. 2025 Jun; 122(6):e70273. View Abstract
  15. Exploring associations between dual sensory impairment and neuropsychiatric disorders: Insights from a prospective cohort study in the UK Biobank. Arch Gerontol Geriatr. 2025 Aug; 135:105865. View Abstract
  16. Associations among Angiotensin-Converting Enzyme, Neuroinflammation, and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Non-Dementia Adults. Neurotox Res. 2025 Apr 04; 43(2):20. View Abstract
  17. Dietary inflammatory index and brain disorders: a Large Prospective Cohort study. Transl Psychiatry. 2025 Mar 27; 15(1):99. View Abstract
  18. PARADISE: Personalized and regional adaptation for HIE disease identification and segmentation. Med Image Anal. 2025 May; 102:103419. View Abstract
  19. Exome sequencing identifies protein-coding variants associated with loneliness and social isolation. J Affect Disord. 2025 Apr 15; 375:192-204. View Abstract
  20. BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): I. MRI and Lesion Labeling. Sci Data. 2025 Jan 11; 12(1):53. View Abstract
  21. Left-Right Brain-Wide Asymmetry of Neuroanatomy in the Mouse Brain. Neuroimage. 2025 Feb 15; 307:121017. View Abstract
  22. Variables associated with cognitive function: an exposome-wide and mendelian randomization analysis. Alzheimers Res Ther. 2025 Jan 07; 17(1):13. View Abstract
  23. Inferring neurocognition using artificial intelligence on brain MRIs. Front Neuroimaging. 2024; 3:1455436. View Abstract
  24. Pathogenic role of acyl coenzyme A binding protein (ACBP) in Cushing's syndrome. Nat Metab. 2024 Dec; 6(12):2281-2299. View Abstract
  25. Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. J Am Coll Cardiol. 2025 Feb 25; 85(7):699-706. View Abstract
  26. Deep learning of structural MRI predicts fluid, crystallized, and general intelligence. Sci Rep. 2024 11 14; 14(1):27935. View Abstract
  27. Analysis of risk factors and establishment of early warning model for recent postoperative complications of colorectal cancer. Front Oncol. 2024; 14:1411817. View Abstract
  28. Osteoarthritis, osteoarthritis treatment and risk of incident dementia: a prospective cohort study based on UK Biobank. Age Ageing. 2024 08 06; 53(8). View Abstract
  29. Tackling heterogeneity in medical federated learning via aligning vision transformers. Artif Intell Med. 2024 09; 155:102936. View Abstract
  30. Large-scale whole-exome sequencing analyses identified protein-coding variants associated with immune-mediated diseases in 350,770 adults. Nat Commun. 2024 Jul 15; 15(1):5924. View Abstract
  31. Identifying modifiable factors and their joint effect on brain health: an exposome-wide association study. Geroscience. 2024 Dec; 46(6):6257-6268. View Abstract
  32. Physical frailty, genetic predisposition, and incident dementia: a large prospective cohort study. Transl Psychiatry. 2024 05 27; 14(1):212. View Abstract
  33. Autism-associated brain differences can be observed in utero using MRI. Cereb Cortex. 2024 04 01; 34(4). View Abstract
  34. Heterogeneously elevated branched-chain/aromatic amino acids among new-onset type-2 diabetes mellitus patients are potentially skewed diabetes predictors. World J Diabetes. 2024 Jan 15; 15(1):53-71. View Abstract
  35. Retrospective Analysis of Presymptomatic Treatment In Sturge-Weber Syndrome. Ann Child Neurol Soc. 2024 Mar; 2(1):60-72. View Abstract
  36. Associations between antipsychotics exposure and dementia risk: A prospective cohort study of 415,100 participants. J Affect Disord. 2024 03 15; 349:201-209. View Abstract
  37. Noninvasive Gamma Sensory Stimulation May Reduce White Matter and Myelin Loss in Alzheimer's Disease. J Alzheimers Dis. 2024; 97(1):359-372. View Abstract
  38. Socioeconomic status, lifestyle and risk of incident dementia: a prospective cohort study of 276730 participants. Geroscience. 2024 04; 46(2):2265-2279. View Abstract
  39. Human-to-monkey transfer learning identifies the frontal white matter as a key determinant for predicting monkey brain age. Front Aging Neurosci. 2023; 15:1249415. View Abstract
  40. Associations of liver dysfunction with incident dementia, cognition, and brain structure: A prospective cohort study of 431?699 adults. J Neurochem. 2024 01; 168(1):26-38. View Abstract
  41. Linking maternal disrupted interaction and infant limbic volumes: The role of infant cortisol output. Psychoneuroendocrinology. 2023 12; 158:106379. View Abstract
  42. Challenges of implementing computer-aided diagnostic models for neuroimages in a clinical setting. NPJ Digit Med. 2023 Jul 13; 6(1):129. View Abstract
  43. Negative versus withdrawn maternal behavior: Differential associations with infant gray and white matter during the first 2?years of life. Hum Brain Mapp. 2023 08 15; 44(12):4572-4589. View Abstract
  44. BOston Neonatal Brain Injury Dataset for Hypoxic Ischemic Encephalopathy (BONBID-HIE): Part I. MRI and Manual Lesion Annotation. bioRxiv. 2023 Jul 03. View Abstract
  45. The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders. Transl Psychiatry. 2023 05 26; 13(1):180. View Abstract
  46. Maternal Childhood Abuse Versus Neglect Associated with Differential Patterns of Infant Brain Development. Res Child Adolesc Psychopathol. 2023 12; 51(12):1919-1932. View Abstract
  47. The genetic architecture of human amygdala volumes and their overlap with common brain disorders. Transl Psychiatry. 2023 03 11; 13(1):90. View Abstract
  48. Associations of Lung Function Decline with Risks of Cognitive Impairment and Dementia: A Meta-Analysis and Systematic Review. J Alzheimers Dis. 2023; 92(3):853-873. View Abstract
  49. Segmentation ability map: Interpret deep features for medical image segmentation. Med Image Anal. 2023 02; 84:102726. View Abstract
  50. Association between multimorbidity status and incident dementia: a prospective cohort study of 245,483 participants. Transl Psychiatry. 2022 12 07; 12(1):505. View Abstract
  51. Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood. Biol Psychiatry. 2023 05 01; 93(9):770-779. View Abstract
  52. Residential greenness and risk of incident dementia: A prospective study of 375,342 participants. Environ Res. 2023 01 01; 216(Pt 3):114703. View Abstract
  53. Investigating the association between cancer and dementia risk: a longitudinal cohort study. Alzheimers Res Ther. 2022 10 05; 14(1):146. View Abstract
  54. Patterns of Neural Functional Connectivity in Infants at Familial Risk of Developmental Dyslexia. JAMA Netw Open. 2022 10 03; 5(10):e2236102. View Abstract
  55. Depression, Depression Treatments, and Risk of Incident Dementia: A Prospective Cohort Study of 354,313 Participants. Biol Psychiatry. 2023 05 01; 93(9):802-809. View Abstract
  56. Deep Relation Learning for Regression and Its Application to Brain Age Estimation. IEEE Trans Med Imaging. 2022 09; 41(9):2304-2317. View Abstract
  57. Modifiable risk factors for incident dementia and cognitive impairment: An umbrella review of evidence. J Affect Disord. 2022 10 01; 314:160-167. View Abstract
  58. A Role for Data Science in Precision Nutrition and Early Brain Development. Front Psychiatry. 2022; 13:892259. View Abstract
  59. Arabidopsis ROOT ELONGATION RECEPTOR KINASES negatively regulate root growth putatively via altering cell wall remodeling gene expression. J Integr Plant Biol. 2022 Aug; 64(8):1502-1513. View Abstract
  60. Cataract, Cataract Surgery, and Risk of Incident Dementia: A Prospective Cohort Study of 300,823 Participants. Biol Psychiatry. 2023 05 01; 93(9):810-819. View Abstract
  61. Increased Breastfeeding Proportion Is Associated with Improved Gross Motor Skills at 3-5 Years of Age: A Pilot Study. Nutrients. 2022 May 26; 14(11). View Abstract
  62. Deep learning of birth-related infant clavicle fractures: a potential virtual consultant for fracture dating. Pediatr Radiol. 2022 10; 52(11):2206-2214. View Abstract
  63. Association of life course adiposity with risk of incident dementia: a prospective cohort study of 322,336 participants. Mol Psychiatry. 2022 08; 27(8):3385-3395. View Abstract
  64. Time spent in outdoor light is associated with the risk of dementia: a prospective cohort study of 362094 participants. BMC Med. 2022 04 25; 20(1):132. View Abstract
  65. How Machine Learning is Powering Neuroimaging to Improve Brain Health. Neuroinformatics. 2022 10; 20(4):943-964. View Abstract
  66. Identifying causal genes for depression via integration of the proteome and transcriptome from brain and blood. Mol Psychiatry. 2022 06; 27(6):2849-2857. View Abstract
  67. Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer. Cell Death Dis. 2022 03 04; 13(3):206. View Abstract
  68. Study protocol: retrospectively mining multisite clinical data to presymptomatically predict seizure onset for individual patients with Sturge-Weber. BMJ Open. 2022 Feb 04; 12(2):e053103. View Abstract
  69. Peripheral immunity is associated with the risk of incident dementia. Mol Psychiatry. 2022 04; 27(4):1956-1962. View Abstract
  70. Validation of external and internal exposome of the findings associated to cerebral small vessel disease: A Mendelian randomization study. J Cereb Blood Flow Metab. 2022 06; 42(6):1078-1090. View Abstract
  71. The Association of Serum Uric Acid Level, Gout, and Alzheimer's Disease: A Bidirectional Mendelian Randomization Study. J Alzheimers Dis. 2022; 89(3):1063-1073. View Abstract
  72. The Association Between Osteoarthritis with Risk of Dementia and Cognitive Impairment: A Meta-Analysis and Systematic Review. J Alzheimers Dis. 2022; 89(4):1159-1172. View Abstract
  73. Risk of Dementia in Cancer Survivors: A Meta-Analysis of Population-Based Cohort Studies. J Alzheimers Dis. 2022; 89(1):367-380. View Abstract
  74. Assessment of Maternal Macular Pigment Optical Density (MPOD) as a Potential Marker for Dietary Carotenoid Intake during Lactation in Humans. Nutrients. 2021 Dec 31; 14(1). View Abstract
  75. Global-Local Transformer for Brain Age Estimation. IEEE Trans Med Imaging. 2022 01; 41(1):213-224. View Abstract
  76. Evolution of RGF/GLV/CLEL Peptide Hormones and Their Roles in Land Plant Growth and Regulation. Int J Mol Sci. 2021 Dec 13; 22(24). View Abstract
  77. Can updated climate pledges limit warming well below 2°C? Science. 2021 Nov 05; 374(6568):693-695. View Abstract
  78. Optimal Method for Fetal Brain Age Prediction Using Multiplanar Slices From Structural Magnetic Resonance Imaging. Front Neurosci. 2021; 15:714252. View Abstract
  79. Maternal Childhood Maltreatment Is Associated With Lower Infant Gray Matter Volume and Amygdala Volume During the First Two Years of Life. Biol Psychiatry Glob Open Sci. 2022 Oct; 2(4):440-449. View Abstract
  80. Identification of novel drug targets for Alzheimer's disease by integrating genetics and proteomes from brain and blood. Mol Psychiatry. 2021 10; 26(10):6065-6073. View Abstract
  81. Functional Connectivity in Infancy and Toddlerhood Predicts Long-Term Language and Preliteracy Outcomes. Cereb Cortex. 2021 08 04; 32(4). View Abstract
  82. Multi-channel attention-fusion neural network for brain age estimation: Accuracy, generality, and interpretation with 16,705 healthy MRIs across lifespan. Med Image Anal. 2021 08; 72:102091. View Abstract
  83. Quantification of magnetic resonance spectroscopy data using a combined reference: Application in typically developing infants. NMR Biomed. 2021 07; 34(7):e4520. View Abstract
  84. JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in Arabidopsis. Mol Plant. 2021 05 03; 14(5):732-747. View Abstract
  85. The prognostic significance of single-nucleotide polymorphism array-based whole-genome analysis and uniparental disomy in myelodysplastic syndrome. Int J Lab Hematol. 2021 Oct; 43(5):1062-1069. View Abstract
  86. Hidden Vacancy Benefit in Monolayer 2D Semiconductors. Adv Mater. 2021 Feb; 33(7):e2007051. View Abstract
  87. Voxelwise and Regional Brain Apparent Diffusion Coefficient Changes on MRI from Birth to 6 Years of Age. Radiology. 2021 02; 298(2):415-424. View Abstract
  88. Changes of air quality and its associated health and economic burden in 31 provincial capital cities in China during COVID-19 pandemic. Atmos Res. 2021 Feb; 249:105328. View Abstract
  89. A Collaborative Dictionary Learning Model for Nasopharyngeal Carcinoma Segmentation on Multimodalities MR Sequences. Comput Math Methods Med. 2020; 2020:7562140. View Abstract
  90. Fully Automatic Arteriovenous Segmentation in Retinal Images via Topology-Aware Generative Adversarial Networks. Interdiscip Sci. 2020 Sep; 12(3):323-334. View Abstract
  91. Localizing central swallowing functions by combining non-invasive brain stimulation with neuroimaging. Brain Stimul. 2020 Sep - Oct; 13(5):1207-1210. View Abstract
  92. Blood Pressure and Risks of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of 209 Prospective Studies. Hypertension. 2020 07; 76(1):217-225. View Abstract
  93. BRAIN AGE ESTIMATION USING LSTM ON CHILDREN'S BRAIN MRI. Proc IEEE Int Symp Biomed Imaging. 2020 Apr; 2020:420-423. View Abstract
  94. Editorial: Artificial Intelligence for Medical Image Analysis of Neuroimaging Data. Front Neurosci. 2020; 14:480. View Abstract
  95. Infant FreeSurfer: An automated segmentation and surface extraction pipeline for T1-weighted neuroimaging data of infants 0-2 years. Neuroimage. 2020 09; 218:116946. View Abstract
  96. WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC. Signal Transduct Target Ther. 2020 04 15; 5(1):36. View Abstract
  97. Maternal Dietary Intake of Omega-3 Fatty Acids Correlates Positively with Regional Brain Volumes in 1-Month-Old Term Infants. Cereb Cortex. 2020 04 14; 30(4):2057-2069. View Abstract
  98. Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills. Hum Brain Mapp. 2020 07; 41(10):2827-2845. View Abstract
  99. Experimental Treatment of SIV-Infected Macaques via Autograft of CCR5-Disrupted Hematopoietic Stem and Progenitor Cells. Mol Ther Methods Clin Dev. 2020 Jun 12; 17:520-531. View Abstract
  100. Visualizing H2O molecules reacting at TiO2 active sites with transmission electron microscopy. Science. 2020 01 24; 367(6476):428-430. View Abstract
  101. Mining multi-site clinical data to develop machine learning MRI biomarkers: application to neonatal hypoxic ischemic encephalopathy. J Transl Med. 2019 11 21; 17(1):385. View Abstract
  102. Defect-Engineered Atomically Thin MoS2 Homogeneous Electronics for Logic Inverters. Adv Mater. 2020 Jan; 32(2):e1906646. View Abstract
  103. Deformable MRI-Ultrasound registration using correlation-based attribute matching for brain shift correction: Accuracy and generality in multi-site data. Neuroimage. 2019 11 15; 202:116094. View Abstract
  104. Evaluation of MRI to Ultrasound Registration Methods for Brain Shift Correction: The CuRIOUS2018 Challenge. IEEE Trans Med Imaging. 2020 03; 39(3):777-786. View Abstract
  105. Publisher Correction: Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI. Sci Rep. 2019 Jun 14; 9(1):8721. View Abstract
  106. Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine. JACC Basic Transl Sci. 2019 Apr; 4(2):176-187. View Abstract
  107. Self-Healing Originated van der Waals Homojunctions with Strong Interlayer Coupling for High-Performance Photodiodes. ACS Nano. 2019 Mar 26; 13(3):3280-3291. View Abstract
  108. Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI. Sci Rep. 2018 11 20; 8(1):17062. View Abstract
  109. Analysis of glucose-derived amino acids involved in one-carbon and cancer metabolism by stable-isotope tracing gas chromatography mass spectrometry. Anal Biochem. 2019 02 01; 566:1-9. View Abstract
  110. Field of View Normalization in Multi-Site Brain MRI. Neuroinformatics. 2018 10; 16(3-4):431-444. View Abstract
  111. Comparison of two detection systems for circulating tumor cells among patients with renal cell carcinoma. Int Urol Nephrol. 2018 Oct; 50(10):1801-1809. View Abstract
  112. Quantitative Apparent Diffusion Coefficient Mapping May Predict Seizure Onset in Children With Sturge-Weber Syndrome. Pediatr Neurol. 2018 07; 84:32-38. View Abstract
  113. Quantitative Apparent Diffusion Coefficient Mapping May Predict Seizure Onset in Children With Sturge-Weber Syndrome. Pediatric Neurology. 2018. View Abstract
  114. Cancer imaging phenomics toolkit: quantitative imaging analytics for precision diagnostics and predictive modeling of clinical outcome. J Med Imaging (Bellingham). 2018 Jan; 5(1):011018. View Abstract
  115. ABCD1 dysfunction alters white matter microvascular perfusion. Brain. 2017 Dec 01; 140(12):3139-3152. View Abstract
  116. Radiomics in Brain Tumor: Image Assessment, Quantitative Feature Descriptors, and Machine-Learning Approaches. AJNR Am J Neuroradiol. 2018 02; 39(2):208-216. View Abstract
  117. Automatic Categorization and Scoring of Solid, Part-Solid and Non-Solid Pulmonary Nodules in CT Images with Convolutional Neural Network. Sci Rep. 2017 09 01; 7(1):8533. View Abstract
  118. Poly(4-styrenesulfonate)-induced sulfur vacancy self-healing strategy for monolayer MoS2 homojunction photodiode. Nat Commun. 2017 06 22; 8:15881. View Abstract
  119. eCurves: A Temporal Shape Encoding. IEEE Trans Biomed Eng. 2018 04; 65(4):733-744. View Abstract
  120. Using clinically acquired MRI to construct age-specific ADC atlases: Quantifying spatiotemporal ADC changes from birth to 6-year old. Hum Brain Mapp. 2017 06; 38(6):3052-3068. View Abstract
  121. Multicenter validation of prostate tumor localization using multiparametric MRI and prior knowledge. Med Phys. 2017 Mar; 44(3):949-961. View Abstract
  122. Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma. J Neurooncol. 2017 02; 131(3):603-610. View Abstract
  123. Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression. Cell Rep. 2016 10 04; 17(2):366-373. View Abstract
  124. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res. 2016 06; 26(6):686-98. View Abstract
  125. MUSE: MUlti-atlas region Segmentation utilizing Ensembles of registration algorithms and parameters, and locally optimal atlas selection. Neuroimage. 2016 Feb 15; 127:186-195. View Abstract
  126. Brain extraction in pediatric ADC maps, toward characterizing neuro-development in multi-platform and multi-institution clinical images. Neuroimage. 2015 Nov 15; 122:246-61. View Abstract
  127. Methodology to study the three-dimensional spatial distribution of prostate cancer and their dependence on clinical parameters. J Med Imaging (Bellingham). 2015 Jul; 2(3):037502. View Abstract
  128. Ferroptosis: A missing puzzle piece in the p53 blueprint? Mol Cell Oncol. 2016 May; 3(3):e1046581. View Abstract
  129. Handbook of Biomedical Imaging; Methodologies and Clinical Research. Graph-based Deformable Image Registration. 2015. View Abstract
  130. SPIE Medical Imaging. Quantification of Tumor Changes during Neoadjuvant Chemotherapy with Longitudinal Breast DCE-MRI Registration. 2015; 9414. View Abstract
  131. p53 Protein-mediated regulation of phosphoglycerate dehydrogenase (PHGDH) is crucial for the apoptotic response upon serine starvation. J Biol Chem. 2015 Jan 02; 290(1):457-66. View Abstract
  132. Right ventricle segmentation from cardiac MRI: a collation study. Med Image Anal. 2015 Jan; 19(1):187-202. View Abstract
  133. Deformable registration for quantifying longitudinal tumor changes during neoadjuvant chemotherapy. Magn Reson Med. 2015 Jun; 73(6):2343-56. View Abstract
  134. Comparative evaluation of registration algorithms in different brain databases with varying difficulty: results and insights. IEEE Trans Med Imaging. 2014 Oct; 33(10):2039-65. View Abstract
  135. Audits of the quality of perioperative antibiotic prophylaxis in Shandong Province, China, 2006 to 2011. Am J Infect Control. 2014 May; 42(5):516-20. View Abstract
  136. Neuroanatomical classification in a population-based sample of psychotic major depression and bipolar I disorder with 1 year of diagnostic stability. Biomed Res Int. 2014; 2014:706157. View Abstract
  137. Evaluation of prostate segmentation algorithms for MRI: the PROMISE12 challenge. Med Image Anal. 2014 Feb; 18(2):359-73. View Abstract
  138. Multi-atlas skull-stripping. Acad Radiol. 2013 Dec; 20(12):1566-76. View Abstract
  139. Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers. Neuroimage Clin. 2014; 4:164-73. View Abstract
  140. Hierarchical Pd-Sn alloy nanosheet dendrites: an economical and highly active catalyst for ethanol electrooxidation. Sci Rep. 2013; 3:1181. View Abstract
  141. Neuroanatomical pattern classification in a population-based sample of first-episode schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jun 03; 43:116-25. View Abstract
  142. Development and Validations of a Deformable Registration Algorithm of Medical Images: Applications to Brain, Breast and Prostate Studies. 2012. View Abstract
  143. Validation of DRAMMS among 12 Popular Methods in Cross-Subject Cardiac MRI Registration. Biomed Image Regist Proc. 2012 Jul; 7359:209-219. View Abstract
  144. Temporal shape analysis via the spectral signature. Med Image Comput Comput Assist Interv. 2012; 15(Pt 2):49-56. View Abstract
  145. DRAMMS: Deformable registration via attribute matching and mutual-saliency weighting. Med Image Anal. 2011 Aug; 15(4):622-39. View Abstract
  146. Detecting mutually-salient landmark pairs with MRF regularization. IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI). 2010; 400-403. View Abstract
  147. Simultaneous geometric--iconic registration. Med Image Comput Comput Assist Interv. 2010; 13(Pt 2):676-83. View Abstract
  148. Sampling the spatial patterns of cancer: optimized biopsy procedures for estimating prostate cancer volume and Gleason Score. Med Image Anal. 2009 Aug; 13(4):609-20. View Abstract
  149. Non-rigid registration between histological and MR images of the prostate: a joint segmentation and registration framework. Mathematical Method in Biomedical Image Analysis (MMBIA). 2009; 125-132. View Abstract
  150. DRAMMS: deformable registration via attribute matching and mutual-saliency weighting. Inf Process Med Imaging. 2009; 21:50-62. View Abstract
  151. Multiparametric tissue characterization of brain neoplasms and their recurrence using pattern classification of MR images. Acad Radiol. 2008 Aug; 15(8):966-77. View Abstract
  152. Registering histologic and MR images of prostate for image-based cancer detection. Acad Radiol. 2007 Nov; 14(11):1367-81. View Abstract
  153. Simultaneous estimation and segmentation of T1 map for breast parenchyma measurement. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, (ISBI). 2007; 332-335. View Abstract
  154. Probabilistic segmentation of brain tumors based on multi-modality magnetic resonance images. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, (ISBI). 2007; 600-603. View Abstract
  155. System and Method for Automatic Extraction of Spinal Cord from 3D Volumetric Images. 2007. View Abstract

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