Information

Related Research Units

Emergency Medicine Research

Research Overview

The research interests of Dr. Lyons include the diagnosis and management of children with meningitis, seizures and head trauma. He has also begun work on health information technology, care fragmentation and health information exchange. His previous work has included studies of enteroviral meningitis, Lyme meningitis, status epilepticus, head trauma and skull fractures.

 

Research Background

Todd Lyons received his MD in Medicine from the University of Connecticut School of Medicine. He did his internship and residency at the Boston Combined Residency Program at Boston Children’s Hospital where he was chief resident. He completed his fellowship in Pediatric Emergency Medicine at Boston Children’s Hospital. Dr. Lyons completed the program in clinic-effectiveness at the Harvard School of Public Health. He is a research fellow in the Division of Emergency Medicine under the NIH T32 training program. He joined the faculty of the Division of Emergency Medicine at Boston Children’s Hospital in 2015.

 

Education

Medical School

University of Connecticut School of Medicine
2008 Farmington CT

Internship

Boston Combined Residency Program (BCRP)
2009 Boston MA

Residency

Boston Combined Residency Program (BCRP)
2011 Boston MA

Residency

Chief Resident Boston Combined Residency Program (BCRP)
2012 Boston MA

Fellowship

Pediatric Emergency Medicine Boston Children's Hospital
2015 Boston MA

Publications

  1. Development of a reference standard to assign bacterial versus viral infection etiology using an all-inclusive methodology for comparison of novel diagnostic tool performance. Clin Infect Dis. 2025 Jan 03. View Abstract
  2. Optimizing Advanced Imaging of the Pediatric Patient in the Emergency Department: Policy Statement. Ann Emerg Med. 2024 Aug; 84(2):e13-e23. View Abstract
  3. Managing the Swollen Knee in a Child. Ann Emerg Med. 2024 Nov; 84(5):500-507. View Abstract
  4. Optimizing Advanced Imaging of the Pediatric Patient in the Emergency Department: Policy Statement. Pediatrics. 2024 Jul 01; 154(1). View Abstract
  5. Optimizing Advanced Imaging of the Pediatric Patient in the Emergency Department: Technical Report. Pediatrics. 2024 Jul 01; 154(1). View Abstract
  6. Optimizing Advanced Imaging of the Pediatric Patient in the Emergency Department: Policy Statement. J Am Coll Radiol. 2024 Jul; 21(7):1108-1118. View Abstract
  7. Optimizing Advanced Imaging of the Pediatric Patient in the Emergency Department: Technical Report. J Am Coll Radiol. 2024 Jul; 21(7):e37-e69. View Abstract
  8. Emergency Department Evaluation of Young Infants With Head Injury. Pediatrics. 2024 Jun 01; 153(6). View Abstract
  9. Utility of Synovial Fluid Biomarkers for Culture-Positive Septic Arthritis in a Lyme Disease-Endemic Region. Pediatr Emerg Care. 2024 Jul 01; 40(7):e82-e88. View Abstract
  10. Harnessing the Power of Generative AI for Clinical Summaries: Perspectives From Emergency Physicians. Ann Emerg Med. 2024 Aug; 84(2):128-138. View Abstract
  11. Surgical Specialty Consultation for Pediatric Facial Laceration Repair: An American and Canadian Survey. Pediatr Emerg Care. 2024 Aug 01; 40(8):e120-e125. View Abstract
  12. A Novel Risk Score to Guide the Evaluation of Acute Hematogenous Osteomyelitis in Children. Pediatrics. 2024 Jan 01; 153(2). View Abstract
  13. Biomarkers for Pediatric Bacterial Musculoskeletal Infections in Lyme Disease-Endemic Regions. Pediatrics. 2023 Aug 01; 152(2). View Abstract
  14. Patterns and Predictors of Health Care Utilization After Pediatric Concussion: A Retrospective Cohort Study. Acad Pediatr. 2024 Jan-Feb; 24(1):51-58. View Abstract
  15. Comprehensiveness of Testing Among Herpes Simplex Virus Infected Infants: A Multicenter Cohort Study. Pediatr Infect Dis J. 2022 10 01; 41(10):851-853. View Abstract
  16. A Clinical Prediction Rule for Bacterial Musculoskeletal Infections in Children with Monoarthritis in Lyme Endemic Regions. Ann Emerg Med. 2022 09; 80(3):225-234. View Abstract
  17. Paediatric post-concussive symptoms: symptom clusters and clinical phenotypes. Br J Sports Med. 2022 Jul; 56(14):785-791. View Abstract
  18. Validation of Septic Knee Monoarthritis Prediction Rule in a Lyme Disease Endemic Area. Pediatr Emerg Care. 2022 Feb 01; 38(2):e881-e885. View Abstract
  19. Attending-Provider Handoffs and Pediatric Emergency Department Revisits. Pediatr Emerg Care. 2021 Nov 01; 37(11):e679-e685. View Abstract
  20. Trends in Management of Simple Febrile Seizures at US Children's Hospitals. Pediatrics. 2021 11; 148(5). View Abstract
  21. Predictors of Invasive Herpes Simplex Virus Infection in Young Infants. Pediatrics. 2021 09; 148(3). View Abstract
  22. Prediction of patient disposition: comparison of computer and human approaches and a proposed synthesis. J Am Med Inform Assoc. 2021 07 30; 28(8):1736-1745. View Abstract
  23. Care of Children with Supraventricular Tachycardia in the Emergency Department. Pediatr Cardiol. 2021 Mar; 42(3):569-577. View Abstract
  24. Trends in Severe Pediatric Emergency Conditions in a National Cohort, 2008 to 2014. Pediatr Emerg Care. 2020 Nov; 36(11):e620-e621. View Abstract
  25. The Champagne Tap: Time to Pop the Cork? Acad Emerg Med. 2020 11; 27(11):1194-1198. View Abstract
  26. Performance of the Modified Boston and Philadelphia Criteria for Invasive Bacterial Infections. Pediatrics. 2020 04; 145(4). View Abstract
  27. Trends in Capability of Hospitals to Provide Definitive Acute Care for Children: 2008 to 2016. Pediatrics. 2020 01; 145(1). View Abstract
  28. Diagnostic Performance of C6 Enzyme Immunoassay for Lyme Arthritis. Pediatrics. 2020 01; 145(1). View Abstract
  29. Preventing injuries must be a priority to prevent disease in the twenty-first century. Pediatr Res. 2020 01; 87(2):282-292. View Abstract
  30. Racial and Ethnic Differences in Emergency Department Utilization and Diagnosis for Sports-Related Head Injuries. Front Neurol. 2019; 10:690. View Abstract
  31. Association of Herpes Simplex Virus Testing with Hospital Length of Stay for Infants =60 Days of Age Undergoing Evaluation for Meningitis. J Hosp Med. 2019 08 01; 14(8):492-495. View Abstract
  32. Case 1: A Medically Complex 10-month-old Boy with Lethargy. Pediatr Rev. 2019 Feb; 40(2):79-81. View Abstract
  33. Risk of Serious Infections Associated with Biologic Agents in Juvenile Idiopathic Arthritis: A Systematic Review and Meta-Analyses. J Pediatr. 2019 01; 204:162-171.e3. View Abstract
  34. Use of a National Database to Assess Pediatric Emergency Care Across United States Emergency Departments. Acad Emerg Med. 2018 12; 25(12):1355-1364. View Abstract
  35. Accuracy of Herpes Simplex Virus Polymerase Chain Reaction Testing of the Blood for Central Nervous System Herpes Simplex Virus Infections in Infants. J Pediatr. 2018 09; 200:274-276.e1. View Abstract
  36. Timing and Location of Emergency Department Revisits. Pediatrics. 2018 05; 141(5). View Abstract
  37. Herpes Simplex Virus Infection in Infants Undergoing Meningitis Evaluation. Pediatrics. 2018 02; 141(2). View Abstract
  38. A Systematic Review and Meta-Analysis of the Management and Outcomes of Isolated Skull Fractures in Children. Ann Emerg Med. 2018 06; 71(6):714-724.e2. View Abstract
  39. Patients Visiting Multiple Emergency Departments: Patterns, Costs, and Risk Factors. Acad Emerg Med. 2017 11; 24(11):1349-1357. View Abstract
  40. Correction of Cerebrospinal Fluid Protein in Infants With Traumatic Lumbar Punctures. Pediatr Infect Dis J. 2017 Oct; 36(10):1006-1008. View Abstract
  41. Utility of Lumbar Puncture in Children Presenting With Status Epilepticus. Pediatr Emerg Care. 2017 Aug; 33(8):544-547. View Abstract
  42. Impact of Enteroviral Polymerase Chain Reaction Testing on Length of Stay for Infants 60 Days Old or Younger. J Pediatr. 2017 10; 189:169-174.e2. View Abstract
  43. Interpretation of Cerebrospinal Fluid White Blood Cell Counts in Young Infants With a Traumatic Lumbar Puncture. Ann Emerg Med. 2017 May; 69(5):622-631. View Abstract
  44. A QI Initiative to Reduce Hospitalization for Children With Isolated Skull Fractures. Pediatrics. 2016 06; 137(6). View Abstract
  45. Yield of emergent neuroimaging in children with new-onset seizure and status epilepticus. Seizure. 2016 Feb; 35:4-10. View Abstract
  46. Quality Improvement Effort to Reduce Cranial CTs for Children With Minor Blunt Head Trauma. Pediatrics. 2015 Jul; 136(1):e227-33. View Abstract
  47. Pediatric status epilepticus: how common is cerebrospinal fluid pleocytosis in the absence of infection? Seizure. 2014 Aug; 23(7):573-5. View Abstract
  48. Enteroviral testing and length of hospital stay for children evaluated for lyme meningitis. J Emerg Med. 2013 Jun; 44(6):1196-200. View Abstract
  49. Treatment complications in children with lyme meningitis. Pediatr Infect Dis J. 2012 Oct; 31(10):1032-5. View Abstract
  50. Electrocardiograph abnormalities in children with Lyme meningitis. Journal of the Pediatric Infectious Disease Society. 2012; 1(4):293-298. View Abstract
  51. Electrocardiograph Abnormalities in Children With Lyme Meningitis. J Pediatric Infect Dis Soc. 2012 Dec; 1(4):293-8. View Abstract
  52. Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis. J Hosp Med. 2012 Sep; 7(7):517-20. View Abstract
  53. Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis. Pediatrics. 2012 Jan; 129(1):e46-53. View Abstract
  54. Mold and Alternaria skin test reactivity and asthma in children in Connecticut. Ann Allergy Asthma Immunol. 2011 Apr; 106(4):301-7. View Abstract

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