The Schwarz Lab works at the intersection of neuroscience and cell biology. In the last decade, the mechanisms of axonal transport and the dynamics of mitochondria have become primary areas of interest and combine fundamental cell biology with insight into the etiology and treatment of neurodegenerative disorders. Our approach has been to use whatever system is most pertinent to the scientific question, from Drosophila genetics to rodent neurons, to patient-derived iPSCs. We combine advanced imaging methods, molecular biology, genetics, and pharmacology to reach our goal of a mechanistic understanding. One current focus is on neurodegenerative mechanisms and, in particular, how defects in mitochondrial transport and clearance contribute to neuropathology in Parkinson’s Disease and ALS. These studies complement our other projects on synapse formation and the cell biological processes that allow a growth cone to transform into a functional synaptic bouton.
Research Background
Selected Publications
Chung J.Y., Steen J.A., Schwarz T.L. (2016) Phosphorylation-Induced Motor Shedding Is Required at Mitosis for Proper Distribution and Passive Inheritance of Mitochondria Cell Reports. 16(8):2142-55. doi: 10.1016/j.celrep.2016.07.055. Epub 2016 Aug 11.
Ashrafi, G., Schlehe, J. S., LaVoie, M. J., & Schwarz, T. L. (2014). Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. The Journal of Cell Biology, 206(5), 655–670.
Pekkurnaz, G., Trinidad, J.C., Wang, X., Kong, D. and Schwarz, T.L. (2014). Glucose Regulates Mitochondrial Motility via Milton Modification by O-GlcNAc Transferase. Cell, 158:54-68.
Teodoro, R.O., Pekkurnaz, G., Nasser, A., Higashi-Kovtun, M.E., Balakireva, M., McLachlan, I.G., Camonis, J., and Schwarz, T.L. (2013) Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst. EMBO J. 32: 2039-55.
Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y.L., Selkoe, D., Rice, S.J., Steen, J., LaVoie, M.J., and Schwarz, T.L. (2011) PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147:893-907.
Mosca, T.J. and Schwarz, T.L. (2010) The nuclear import of Frizzled2-C by Importins beta11 and alpha2 promotes postsynaptic development. Nat Neurosci. 66:624-7.
Kurshan, P.T., Oztan, A. and Schwarz, T.L. (2009) Presynaptic α2δ-3 protein is required for synaptic morphogenesis independent of its Ca++-channel functions. Nature Neuroscience 12:1411-1419. Wang, X. and Schwarz, T.L. (2009) The mechanism of Ca++ regulation of kinesin-mediated mitochondrial motility. Cell 136:163-174.
Pack-Chung, E., Kurshan, P.T., Dickman, D.K., and Schwarz, T.L. (2007) A Drosophila Kinesin Required for Synaptic Bouton Formation and Synaptic Vesicle Transport. Nature Neuroscience 10:980-989.
Dickman, D.K, Horne, J.A., Meinertzhagen, I.A., and Schwarz, T.L. (2005) A slowed classical pathway rather than kiss-and-run mediates endocytosis at synapses lacking synaptojanin and endophilin. Cell 123:521-533.
Publications
Miro GTPase domains regulate the assembly of the mitochondrial motor-adaptor complex. Life Sci Alliance. 2023 01; 6(1). View Abstract
Virtual screening for small-molecule pathway regulators by image-profile matching. Cell Syst. 2022 09 21; 13(9):724-736.e9. View Abstract
Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal Mitochondria. Front Cell Neurosci. 2022; 16:852245. View Abstract
Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy. Neuron. 2022 05 04; 110(9):1516-1531.e9. View Abstract
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons. Mol Psychiatry. 2022 04; 27(4):1970-1989. View Abstract
FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply. J Cell Biol. 2021 10 04; 220(10). View Abstract
zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways. J Cell Biol. 2021 09 06; 220(9). View Abstract
Kymolyzer, a Semi-Autonomous Kymography Tool to Analyze Intracellular Motility. Curr Protoc Cell Biol. 2020 06; 87(1):e107. View Abstract
QuoVadoPro, an Autonomous Tool for Measuring Intracellular Dynamics using Temporal Variance. Curr Protoc Cell Biol. 2020 06; 87(1):e108. View Abstract
A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport. Cell Rep. 2019 Sep 17; 28(12):3224-3237.e5. View Abstract
The light-sensitive dimerizer zapalog reveals distinct modes of immobilization for axonal mitochondria. Nat Cell Biol. 2019 06; 21(6):768-777. View Abstract
Kinetochore Proteins Have a Post-Mitotic Function in Neurodevelopment. Dev Cell. 2019 03 25; 48(6):873-882.e4. View Abstract
Search for the Exotic Meson X(5568) with the Collider Detector at Fermilab. Phys Rev Lett. 2018 May 18; 120(20):202006. View Abstract
Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron. Phys Rev Lett. 2018 Jan 26; 120(4):042001. View Abstract
Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture. Neuron. 2017 Nov 01; 96(3):651-666. View Abstract
A high mitochondrial transport rate characterizes CNS neurons with high axonal regeneration capacity. PLoS One. 2017; 12(9):e0184672. View Abstract
The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration. Neuron. 2017 05 03; 94(3):689. View Abstract
Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia. Eur J Cell Biol. 2017 May; 96(3):276-288. View Abstract
O-GlcNAc Transferase Is Essential for Sensory Neuron Survival and Maintenance. J Neurosci. 2017 02 22; 37(8):2125-2136. View Abstract
The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration. Neuron. 2016 Dec 21; 92(6):1294-1307. View Abstract
Filamin, a synaptic organizer in Drosophila, determines glutamate receptor composition and membrane growth. Elife. 2016 12 03; 5. View Abstract
Neurotoxic mechanisms of paclitaxel are local to the distal axon and independent of transport defects. Exp Neurol. 2017 Feb; 288:153-166. View Abstract
Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proc Natl Acad Sci U S A. 2016 10 11; 113(41):E6097-E6106. View Abstract
Phosphorylation-Induced Motor Shedding Is Required at Mitosis for Proper Distribution and Passive Inheritance of Mitochondria. Cell Rep. 2016 08 23; 16(8):2142-2155. View Abstract
Urocanic Acid: An Endogenous Regulator of Langerhans Cells. J Invest Dermatol. 2016 08; 136(8):1735-1737. View Abstract
32nd International Austrian Winter Symposium : Zell am See, the Netherlands. 20-23 January 2016. EJNMMI Res. 2016 Apr; 6(Suppl 1):32. View Abstract
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. View Abstract
Tevatron Combination of Single-Top-Quark Cross Sections and Determination of the Magnitude of the Cabibbo-Kobayashi-Maskawa Matrix Element V_{tb}. Phys Rev Lett. 2015 Oct 09; 115(15):152003. View Abstract
Search for Resonances Decaying to Top and Bottom Quarks with the CDF Experiment. Phys Rev Lett. 2015 Aug 07; 115(6):061801. View Abstract
A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects. Biotechnol J. 2015 Sep; 10(11):1727-38. View Abstract
Tevatron constraints on models of the Higgs boson with exotic spin and parity using decays to bottom-antibottom quark pairs. Phys Rev Lett. 2015 Apr 17; 114(15):151802. View Abstract
Constraints on models of the Higgs boson with exotic spin and parity using decays to bottom-antibottom quarks in the full CDF data set. Phys Rev Lett. 2015 Apr 10; 114(14):141802. View Abstract
PINK1- and PARK2-mediated local mitophagy in distal neuronal axons. Autophagy. 2015; 11(1):187-9. View Abstract
Measurement of the single top quark production cross section and |Vtb| in events with one charged lepton, large missing transverse energy, and jets at CDF. Phys Rev Lett. 2014 Dec 31; 113(26):261804. View Abstract
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J Cell Biol. 2014 Sep 01; 206(5):655-70. View Abstract
Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry. Ann Rheum Dis. 2015 Nov; 74(11):2043-9. View Abstract
Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase. Cell. 2014 Jul 03; 158(1):54-68. View Abstract
Have you seen? For parkin, it's not all or nothing. EMBO J. 2014 Feb 18; 33(4):277-9. View Abstract
Ral mediates activity-dependent growth of postsynaptic membranes via recruitment of the exocyst. EMBO J. 2013 Aug 28; 32(17):2418-9. View Abstract
The paradox of paclitaxel neurotoxicity: Mechanisms and unanswered questions. Neuropharmacology. 2014 Jan; 76 Pt A:175-83. View Abstract
Mitochondrial trafficking in neurons. Cold Spring Harb Perspect Biol. 2013 Jun 01; 5(6). View Abstract
Search for supersymmetry with like-sign lepton-tau events at CDF. Phys Rev Lett. 2013 May 17; 110(20):201802. View Abstract
The Aryl hydrocarbon receptor is involved in UVR-induced immunosuppression. J Invest Dermatol. 2013 Dec; 133(12):2763-2770. View Abstract
Search for resonant top-antitop production in the lepton plus jets decay mode using the full CDF data set. Phys Rev Lett. 2013 Mar 22; 110(12):121802. View Abstract
Search for a two-Higgs-boson doublet using a simplified model in pp collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2013 Mar 22; 110(12):121801. View Abstract
Measurement of the cross section for prompt isolated diphoton production using the full CDF run II data sample. Phys Rev Lett. 2013 Mar 08; 110(10):101801. View Abstract
Observation of the production of a W boson in association with a single charm quark. Phys Rev Lett. 2013 Feb 15; 110(7):071801. View Abstract
Measurements of the top-quark mass and the tt cross section in the hadronic t+jets decay channel at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2012 Nov 09; 109(19):192001. View Abstract
Search for the standard model Higgs Boson produced in association with top quarks using the full CDF data set. Phys Rev Lett. 2012 Nov 02; 109(18):181802. View Abstract
Measurement of the bottom-strange meson mixing phase in the full CDF data set. Phys Rev Lett. 2012 Oct 26; 109(17):171802. View Abstract
Precision top-quark mass measurement at CDF. Phys Rev Lett. 2012 Oct 12; 109(15):152003. View Abstract
Measurement of the difference in CP-violating asymmetries in D(0)?K(+)K(-) and D(0)?p(+)p(-) decays at CDF. Phys Rev Lett. 2012 Sep 14; 109(11):111801. View Abstract
Combined search for the standard model Higgs boson decaying to a bb pair using the full CDF data set. Phys Rev Lett. 2012 Sep 14; 109(11):111802. View Abstract
Search for the standard model Higgs boson decaying to a bb pair in events with two oppositely charged leptons using the full CDF data set. Phys Rev Lett. 2012 Sep 14; 109(11):111803. View Abstract
Search for the standard model Higgs boson decaying to a bb pair in events with one charged lepton and large missing transverse energy using the full CDF data set. Phys Rev Lett. 2012 Sep 14; 109(11):111804. View Abstract
Search for the standard model Higgs boson decaying to a bb pair in events with no charged leptons and large missing transverse energy using the full CDF data set. Phys Rev Lett. 2012 Sep 14; 109(11):111805. View Abstract
The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ. 2013 Jan; 20(1):31-42. View Abstract
Evidence for the charmless annihilation decay mode B(s)(0)?p(+)p(-). Phys Rev Lett. 2012 May 25; 108(21):211803. View Abstract
Search for dark matter in events with one jet and missing transverse energy in pp¯ collisions at vs=1.96 TeV. Phys Rev Lett. 2012 May 25; 108(21):211804. View Abstract
Search for a heavy particle decaying to a top quark and a light quark in pp ¯ collisions at vs=1.96 TeV. Phys Rev Lett. 2012 May 25; 108(21):211805. View Abstract
Search for a dark matter candidate produced in association with a single top quark in pp collisions at v[s]=1.96??TeV. Phys Rev Lett. 2012 May 18; 108(20):201802. View Abstract
Measurement of Bs0?Ds(*)+Ds(*)- branching ratios. Phys Rev Lett. 2012 May 18; 108(20):201801. View Abstract
Search for a low-mass standard model Higgs boson in the tt decay channel in pp collisions at sqrt[s]=1.96??TeV. Phys Rev Lett. 2012 May 04; 108(18):181804. View Abstract
The CAP-Gly of p150: one domain, two diseases, and a function at the end. Neuron. 2012 Apr 26; 74(2):211-3. View Abstract
Precise measurement of the W-boson mass with the CDF II detector. Phys Rev Lett. 2012 Apr 13; 108(15):151803. View Abstract
Measurements of the angular distributions of muons from ? decays in pp collisions at sqrt[s] = 1.96??TeV. Phys Rev Lett. 2012 Apr 13; 108(15):151802. View Abstract
Measurement of ZZ production in leptonic final states at sqrt[s] of 1.96 TeV at CDF. Phys Rev Lett. 2012 Mar 09; 108(10):101801. View Abstract
Measurements of the angular distributions in the decays B?K(*)µ(+)µ(-) at CDF. Phys Rev Lett. 2012 Feb 24; 108(8):081807. View Abstract
Observation of exclusive ?? production in pp¯ collisions at vs=1.96 TeV. Phys Rev Lett. 2012 Feb 24; 108(8):081801. View Abstract
Search for a Higgs boson in the diphoton final state in pp collisions at sqrt[s]=1.96??TeV. Phys Rev Lett. 2012 Jan 06; 108(1):011801. View Abstract
Measurement of the B(s)0 lifetime in fully and partially reconstructed B(s)0?D(s)(-)(?p(-))X decays in p¯p collisions at vs=1.96 TeV. Phys Rev Lett. 2011 Dec 30; 107(27):272001. View Abstract
Search for a heavy toplike quark in pp collisions at vs=1.96 TeV. Phys Rev Lett. 2011 Dec 23; 107(26):261801. View Abstract
Measurement of polarization and search for CP violation in B(s)0?ff decays. Phys Rev Lett. 2011 Dec 23; 107(26):261802. View Abstract
Induction of regulatory T cells by a murine ß-defensin. J Immunol. 2012 Jan 15; 188(2):735-43. View Abstract
Top-quark mass measurement using events with missing transverse energy and jets at CDF. Phys Rev Lett. 2011 Dec 02; 107(23):232002. View Abstract
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell. 2011 Nov 11; 147(4):893-906. View Abstract
Observation of the baryonic flavor-changing neutral current decay ?b(0)??µ+µ-. Phys Rev Lett. 2011 Nov 11; 107(20):201802. View Abstract
Search for B(s)(0) ? µ+ µ- and B(0) ? µ+ µ- decays with CDF II. Phys Rev Lett. 2011 Nov 04; 107(19):191801. View Abstract
Search for New T' particles in final states with large jet multiplicities and missing transverse energy in p p collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2011 Nov 04; 107(19):191803. View Abstract
Search for new physics in high pT like-sign dilepton events at CDF II. Phys Rev Lett. 2011 Oct 28; 107(18):181801. View Abstract
Measurement of the cross section for prompt isolated diphoton production in pp collisions at square root(s) = 1.96??TeV. Phys Rev Lett. 2011 Sep 02; 107(10):102003. View Abstract
Observation of the ?(b)(0) baryon. Phys Rev Lett. 2011 Sep 02; 107(10):102001. View Abstract
Limits on anomalous trilinear gauge couplings in Z? events from pp¯ collisions at vs=1.96? TeV. Phys Rev Lett. 2011 Jul 29; 107(5):051802. View Abstract
Search for new dielectron resonances and Randall-Sundrum gravitons at the collider detector at Fermilab. Phys Rev Lett. 2011 Jul 29; 107(5):051801. View Abstract
First search for multijet resonances in sqrt(s) = 1.96??TeV pp collisions. Phys Rev Lett. 2011 Jul 22; 107(4):042001. View Abstract
Search for a very light CP-odd Higgs boson in top quark decays from pp collisions at sqrt(s)]=1.96??TeV. Phys Rev Lett. 2011 Jul 15; 107(3):031801. View Abstract
First measurement of the angular coefficients of Drell-Yan e(+)e(-) pairs in the Z mass region from pp¯ collisions at vs=1.96 TeV. Phys Rev Lett. 2011 Jun 17; 106(24):241801. View Abstract
Search for production of heavy particles decaying to top quarks and invisible particles in pp collisions at vs = 1.96??TeV. Phys Rev Lett. 2011 May 13; 106(19):191801. View Abstract
Measurements of direct CP violating asymmetries in charmless decays of strange bottom mesons and bottom baryons. Phys Rev Lett. 2011 May 06; 106(18):181802. View Abstract
Invariant mass distribution of jet pairs produced in association with a W boson in pp collisions at sqrt[s]=1.96??TeV. Phys Rev Lett. 2011 Apr 29; 106(17):171801. View Abstract
In vitro and in vivo P-glycoprotein transport characteristics of rivaroxaban. J Pharmacol Exp Ther. 2011 Jul; 338(1):372-80. View Abstract
Measurement of the forward-backward asymmetry in the B?K*µ(+)µ(-) decay and first observation of the B(s)0??µ(+)µ(-) decay. Phys Rev Lett. 2011 Apr 22; 106(16):161801. View Abstract
Measurement of the mass difference between t and t quarks. Phys Rev Lett. 2011 Apr 15; 106(15):152001. View Abstract
Search for heavy bottomlike quarks decaying to an electron or muon and jets in pp collisions at vs = 1.96??TeV. Phys Rev Lett. 2011 Apr 08; 106(14):141803. View Abstract
Measurement of b hadron lifetimes in exclusive decays containing a J/? in pp collisions at vs=1.96 TeV. Phys Rev Lett. 2011 Mar 25; 106(12):121804. View Abstract
Search for high mass resonances decaying to muon pairs in vs=1.96 TeV pp collisions. Phys Rev Lett. 2011 Mar 25; 106(12):121801. View Abstract
Top quark mass measurement in the lepton + jets channel using a matrix element method and in situ jet energy calibration. Phys Rev Lett. 2010 Dec 17; 105(25):252001. View Abstract
Improved search for a Higgs boson produced in association with Z ? l+ l- in pp collisions sqrt[s] = 1.96 TeV. Phys Rev Lett. 2010 Dec 17; 105(25):251802. View Abstract
Drosophila Importin-a2 is involved in synapse, axon and muscle development. PLoS One. 2010 Dec 06; 5(12):e15223. View Abstract
Direct top-quark width measurement at CDF. Phys Rev Lett. 2010 Dec 03; 105(23):232003. View Abstract
Search for R-parity violating decays of sneutrinos to eµ, µt, and et pairs in pp collisions at square root s = 1.96 TeV. Phys Rev Lett. 2010 Nov 05; 105(19):191801. View Abstract
Search for new physics with a dijet plus missing E(T) signature in pp collisions at vs=1.96??TeV. Phys Rev Lett. 2010 Sep 24; 105(13):131801. View Abstract
Exclusion of an exotic top quark with -4/3 electric charge using soft lepton tagging. Phys Rev Lett. 2010 Sep 03; 105(10):101801. View Abstract
Search for the production of scalar bottom quarks in pp collisions at square root(s) = 1.96 TeV. Phys Rev Lett. 2010 Aug 20; 105(8):081802. View Abstract
Measurement of W-boson polarization in Top-Quark Decay in pp collisions at sqrt[s]=1.96??TeV. Phys Rev Lett. 2010 Jul 23; 105(4):042002. View Abstract
Sec5, a member of the exocyst complex, mediates Drosophila embryo cellularization. Development. 2010 Aug; 137(16):2773-83. View Abstract
The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development. Nat Neurosci. 2010 Aug; 13(8):935-43. View Abstract
Measurement of the ratio s{tt}/s{Z/?{*}?ll} and precise extraction of the tt cross section. Phys Rev Lett. 2010 Jul 02; 105(1):012001. View Abstract
Search for pair production of supersymmetric top quarks in dilepton events from pp collisions at sqrt[s]=1.96??TeV. Phys Rev Lett. 2010 Jun 25; 104(25):251801. View Abstract
Search for WW and WZ resonances decaying to electron, missing E(T), and two jets in pp collisions at square root(s) = 1.96??TeV. Phys Rev Lett. 2010 Jun 18; 104(24):241801. View Abstract
Are presynaptic proteins predisposed to self-assemble? Neuron. 2010 Jun 10; 66(5):624-7. View Abstract
Measurement of the W+ W- production cross section and search for anomalous WW? and WWZ couplings in pp collisions at square root(s)=1.96??TeV. Phys Rev Lett. 2010 May 21; 104(20):201801. View Abstract
Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci. 2010 Apr 14; 30(15):5253-68. View Abstract
Search for the Higgs boson using neural networks in events with missing energy and b-quark jets in pp collisions at square root(s) = 1.96 TeV. Phys Rev Lett. 2010 Apr 09; 104(14):141801. View Abstract
First measurement of the b-jet cross section in events with a W boson in pp collisions at square root(s) = 1.96 TeV. Phys Rev Lett. 2010 Apr 02; 104(13):131801. View Abstract
Search for technicolor particles produced in association with a W Boson at CDF. Phys Rev Lett. 2010 Mar 19; 104(11):111802. View Abstract
Measurement of the Lambdab0 lifetime in Lambdab0 --> Lambdac+pi- decays in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2010 Mar 12; 104(10):102002. View Abstract
Measurement of the WW + WZ production cross section using the lepton + jets final state at CDF II. Phys Rev Lett. 2010 Mar 12; 104(10):101801. View Abstract
Search for new bottomlike quark pair decays QQ-->(tW(+)(-))(tW(+)(-)in same-charge dilepton events. Phys Rev Lett. 2010 Mar 05; 104(9):091801. View Abstract
Inclusive search for standard model Higgs boson production in the WW decay channel using the CDF II detector. Phys Rev Lett. 2010 Feb 12; 104(6):061803. View Abstract
Search for supersymmetry with gauge-mediated breaking in diphoton events with missing transverse energy at CDF II. Phys Rev Lett. 2010 Jan 08; 104(1):011801. View Abstract
Rab3 dynamically controls protein composition at active zones. Neuron. 2009 Dec 10; 64(5):663-77. View Abstract
Search for the associated production of the standard-model Higgs Boson in the all-hadronic channel. Phys Rev Lett. 2009 Nov 27; 103(22):221801. View Abstract
Search for Higgs bosons predicted in two-Higgs-doublet models via decays to tau lepton pairs in 1.96 TeV pp collisions. Phys Rev Lett. 2009 Nov 13; 103(20):201801. View Abstract
First observation of B(s)(0) --> D(s)(+/-)K(-/+) and measurement of the ratio of branching fractions B(B(s)(0) --> D(s)(+/-)K(-/+)/B(B(s)(0) --> D(s)(+)pi(-)). Phys Rev Lett. 2009 Nov 06; 103(19):191802. View Abstract
Presynaptic alpha2delta-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions. Nat Neurosci. 2009 Nov; 12(11):1415-23. View Abstract
Precision measurement of the X(3872) mass in J/psi pi(+) pi(-) decays. Phys Rev Lett. 2009 Oct 09; 103(15):152001. View Abstract
Search for charged Higgs bosons in decays of top quarks in pp collisions at square root s = 1.96 TeV. Phys Rev Lett. 2009 Sep 04; 103(10):101803. View Abstract
Search for a standard model Higgs boson in WH --> lvbb in pp collisions at square root s = 1.96 TeV. Phys Rev Lett. 2009 Sep 04; 103(10):101802. View Abstract
First observation of vector boson pairs in a hadronic final state at the tevatron collider. Phys Rev Lett. 2009 Aug 28; 103(9):091803. View Abstract
Observation of electroweak single top-quark production. Phys Rev Lett. 2009 Aug 28; 103(9):092002. View Abstract
Search for a fermiophobic Higgs boson decaying into diphotons in pp[over] collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2009 Aug 07; 103(6):061803. View Abstract
Search for the production of narrow tb[over] resonances in 1.9 fb;{-1} of pp[over] collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2009 Jul 24; 103(4):041801. View Abstract
Observation of new charmless decays of bottom hadrons. Phys Rev Lett. 2009 Jul 17; 103(3):031801. View Abstract
Search for long-lived massive charged particles in 1.96 TeV pp collisions. Phys Rev Lett. 2009 Jul 10; 103(2):021802. View Abstract
Evidence for a narrow near-threshold structure in the J/psivarphi mass spectrum in B;{+} --> J/psivarphiK;{+} decays. Phys Rev Lett. 2009 Jun 19; 102(24):242002. View Abstract
Observation of exclusive charmonium production and gammagamma --> micro;{+}micro;{-} in pp[over] collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2009 Jun 19; 102(24):242001. View Abstract
Measurement of the k(T) distribution of particles in jets produced in pp collisions at sqrt(s)=1.96 TeV. Phys Rev Lett. 2009 Jun 12; 102(23):232002. View Abstract
First measurement of the tt[over ] differential cross section dsigma/dM_{tt[over ]} in pp[over ] collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Jun 05; 102(22):222003. View Abstract
Search for Gluino-Mediated Bottom Squark Production in pp[over ] Collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Jun 05; 102(22):221801. View Abstract
Search for exclusive Z-boson production and observation of high-mass pp[over ]-->pgammagammap[over ]-->pl;{+}l;{-}p[over ] events in pp[over ] collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Jun 05; 102(22):222002. View Abstract
Search for the decays B_{(s)};{0} --> e;{+} micro;{-} and B_{(s)};{0} --> e;{+} e;{-} in CDF run II. Phys Rev Lett. 2009 May 22; 102(20):201801. View Abstract
Direct measurement of the W production charge asymmetry in pp collisions at square root s=1.96 TeV. Phys Rev Lett. 2009 May 08; 102(18):181801. View Abstract
Search for top-quark production via flavor-changing neutral currents in W+1 jet events at CDF. Phys Rev Lett. 2009 Apr 17; 102(15):151801. View Abstract
Measurement of the top-quark mass with dilepton events selected using neuroevolution at CDF. Phys Rev Lett. 2009 Apr 17; 102(15):152001. View Abstract
Inclusive search for squark and gluino production in pp[over ] collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Mar 27; 102(12):121801. View Abstract
Measurement of resonance parameters of orbitally excited narrow B0 mesons. Phys Rev Lett. 2009 Mar 13; 102(10):102003. View Abstract
Search for high-mass resonances decaying to dimuons at CDF. Phys Rev Lett. 2009 Mar 06; 102(9):091805. View Abstract
Direct bound on the total decay width of the top quark in pp collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Jan 30; 102(4):042001. View Abstract
Search for maximal flavor violating scalars in same-charge lepton pairs in pp collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Jan 30; 102(4):041801. View Abstract
Search for high-mass e+e- resonances in pp collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2009 Jan 23; 102(3):031801. View Abstract
Search for a Higgs boson decaying to two W bosons at CDF. Phys Rev Lett. 2009 Jan 16; 102(2):021802. View Abstract
The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility. Cell. 2009 Jan 09; 136(1):163-74. View Abstract
Imaging axonal transport of mitochondria. Methods Enzymol. 2009; 457:319-33. View Abstract
Search for the Higgs boson produced in association with Z-->l+l in pp collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2008 Dec 19; 101(25):251803. View Abstract
Measurement of the single-top-quark production cross section at CDF. Phys Rev Lett. 2008 Dec 19; 101(25):252001. View Abstract
Search for supersymmetry in pp collisions at sqrt[s]=1.96 TeV Using the trilepton signature for chargino-neutralino production. Phys Rev Lett. 2008 Dec 19; 101(25):251801. View Abstract
Forward-backward asymmetry in top-quark production in pp[over] collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2008 Nov 14; 101(20):202001. View Abstract
Search for the flavor-changing neutral-current decay t-->Zq in pp collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2008 Nov 07; 101(19):192002. View Abstract
Search for large extra dimensions in final states containing one photon or jet and large missing transverse energy produced in pp collisions at square root[s]=1.96 TeV. Phys Rev Lett. 2008 Oct 31; 101(18):181602. View Abstract
Axonal transport and the delivery of pre-synaptic components. Curr Opin Neurobiol. 2008 Oct; 18(5):495-503. View Abstract
Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction. J Neurosci. 2008 Oct 22; 28(43):10875-84. View Abstract
Search for doubly charged Higgs bosons with lepton-flavor-violating decays involving tau leptons. Phys Rev Lett. 2008 Sep 19; 101(12):121801. View Abstract
Search for pair production of scalar top quarks decaying to a tau lepton and a b quark in pp over collisions at sqrt s=1.96 TeV. Phys Rev Lett. 2008 Aug 15; 101(7):071802. View Abstract
Search for resonant tt[overline] production in pp[overline] collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2008 Jun 13; 100(23):231801. View Abstract
Search for the Higgs boson in events with missing transverse energy and b quark jets produced in pp collisions at square root(s)=1.96 TeV. Phys Rev Lett. 2008 May 30; 100(21):211801. View Abstract
Strong evidence for ZZ production in pp[over] collisions at sqrt[s]=1.96 TeV. Phys Rev Lett. 2008 May 23; 100(20):201801. View Abstract
Observation of the decay Bc+/--->J/psipi+/- and measurement of the Bc+/- mass. Phys Rev Lett. 2008 May 09; 100(18):182002. View Abstract
First flavor-tagged determination of bounds on mixing-induced CP violation in Bs0 --> J/psiphi decays. Phys Rev Lett. 2008 Apr 25; 100(16):161802. View Abstract
Search for heavy toplike quarks using lepton plus jets events in 1.96 TeV pp collisions. Phys Rev Lett. 2008 Apr 25; 100(16):161803. View Abstract
Evidence for D0-D(0) mixing using the CDF II detector. Phys Rev Lett. 2008 Mar 28; 100(12):121802. View Abstract
Measurement of Lifetime and Decay-Width Difference in B_{s};{0}-->J/psivarphi Decays. Phys Rev Lett. 2008 Mar 28; 100(12):121803. View Abstract
Search for Bs0 --> micro+ micro- and B0 --> micro+ micro- decays with 2 fb-1 of pp collisions. Phys Rev Lett. 2008 Mar 14; 100(10):101802. View Abstract
Measurement of inclusive jet cross sections in Z/gamma*(-->e+e-) + jets production in pp[over ] collisions at square root s = 1.96 TeV. Phys Rev Lett. 2008 Mar 14; 100(10):102001. View Abstract
First measurement of W boson production in association with a single Charm quark in pp collisions at sqrt(s)=1.96 TeV. Phys Rev Lett. 2008 Mar 07; 100(9):091803. View Abstract
Observation of orbitally excited B(s) mesons. Phys Rev Lett. 2008 Feb 29; 100(8):082001. View Abstract
Direct measurement of the W Boson width in ppover collisions at square roots = 1.96 TeV. Phys Rev Lett. 2008 Feb 22; 100(7):071801. View Abstract
Cross-section-constrained top-quark mass measurement from dilepton events at the Tevatron. Phys Rev Lett. 2008 Feb 15; 100(6):062005. View Abstract
Search for standard model Higgs bosons produced in association with W bosons. Phys Rev Lett. 2008 Feb 01; 100(4):041801. View Abstract
First observation of the decay Bs0-->Ds-Ds+ and measurement of its branching ratio. Phys Rev Lett. 2008 Jan 18; 100(2):021803. View Abstract
Mutations in a Drosophila alpha2delta voltage-gated calcium channel subunit reveal a crucial synaptic function. J Neurosci. 2008 Jan 02; 28(1):31-8. View Abstract
Search for exclusive gammagamma production in Hadron-Hadron collisions. Phys Rev Lett. 2007 Dec 14; 99(24):242002. View Abstract
Observation of the Heavy Baryons Sigma b and Sigma b*. Phys Rev Lett. 2007 Nov 16; 99(20):202001. View Abstract
Search for chargino-neutralino production in pp collisions at sq rt[s] = 1.96 TeV. Phys Rev Lett. 2007 Nov 09; 99(19):191806. View Abstract
Precise measurement of the top-quark mass in the lepton+jets topology at CDF II. Phys Rev Lett. 2007 Nov 02; 99(18):182002. View Abstract
Search for high-mass diphoton states and limits on Randall-Sundrum gravitons at CDF. Phys Rev Lett. 2007 Oct 26; 99(17):171801. View Abstract
Search for new physics in high-mass electron-positron events in pp[over] collisions at square root s = 1.96 TeV. Phys Rev Lett. 2007 Oct 26; 99(17):171802. View Abstract
First measurement of the W-boson mass in run II of the Tevatron. Phys Rev Lett. 2007 Oct 12; 99(15):151801. View Abstract
Polarizations of J/psi and psi(2S) mesons produced in pp collisions at square root s = 1.96 TeV. Phys Rev Lett. 2007 Sep 28; 99(13):132001. View Abstract
Search for heavy long-lived particles that decay to photons at CDF II. Phys Rev Lett. 2007 Sep 21; 99(12):121801. View Abstract
The osmolyte taurine protects against ultraviolet B radiation-induced immunosuppression. J Immunol. 2007 Sep 15; 179(6):3604-12. View Abstract
Observation and mass measurement of the baryon Xib-. Phys Rev Lett. 2007 Aug 03; 99(5):052002. View Abstract
A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport. Nat Neurosci. 2007 Aug; 10(8):980-9. View Abstract
First measurement of the ratio of central-electron to forward-electron W partial cross sections in pp[over] collisions at (square root)s =1.96 TeV. Phys Rev Lett. 2007 Jun 22; 98(25):251801. View Abstract
Measurement of sigma chi c2 B(chi c2-->J/psi gamma)/sigma chi c1 B(chi c1 -->J/psi gamma) in pp collisions at square root s=1.96 TeV. Phys Rev Lett. 2007 Jun 08; 98(23):232001. View Abstract
Inclusive search for new physics with like-sign dilepton events in pp collisions at square root of s =1.96 TeV. Phys Rev Lett. 2007 Jun 01; 98(22):221803. View Abstract
Observation of WZ production. Phys Rev Lett. 2007 Apr 20; 98(16):161801. View Abstract
Measurement of the top-quark mass in all-hadronic decays in pp collisions at CDF II. Phys Rev Lett. 2007 Apr 06; 98(14):142001. View Abstract
Search for anomalous production of multilepton events in pp collisions at sqrt s=1.96 TeV. Phys Rev Lett. 2007 Mar 30; 98(13):131804. View Abstract
Analysis of the quantum numbers J(PC) of the X(3872) particle. Phys Rev Lett. 2007 Mar 30; 98(13):132002. View Abstract
Measurement of the Lambda b0 lifetime in Lambda b0-->J/psi Lambda 0 in pp collisions at square root s=1.96 TeV. Phys Rev Lett. 2007 Mar 23; 98(12):122001. View Abstract
Measurement of sigma Lambda b0/sigma B0 x B(Lambda b0-->Lambda c+pi-)/B(B0-->D+pi-) in pp collisions at square root s=1.96 TeV. Phys Rev Lett. 2007 Mar 23; 98(12):122002. View Abstract
Observation of exclusive electron-positron production in hadron-hadron collisions. Phys Rev Lett. 2007 Mar 16; 98(11):112001. View Abstract
Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma. Blood. 2007 Jun 01; 109(11):4655-62. View Abstract
Search for V+A current in top-quark decays in pp collisions at sqrts=1.96 TeV. Phys Rev Lett. 2007 Feb 16; 98(7):072001. View Abstract
Measurement of the ratios of branching fractions B(B0s --> Ds- pi+ pi+ pi-)/B(B0-->D- pi+ pi+ pi-) and B(B0s --> Ds- pi+)/B(B0-->D- pi+). Phys Rev Lett. 2007 Feb 09; 98(6):061802. View Abstract
Observation of Bs(0)-Bs(0) oscillations. Phys Rev Lett. 2006 Dec 15; 97(24):242003. View Abstract
Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells. Nat Med. 2006 Dec; 12(12):1372-9. View Abstract
Observation of B(s)0-->K+ K- and measurements of branching fractions of charmless two-body decays of B0 and B(s)0 mesons in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2006 Nov 24; 97(21):211802. View Abstract
Deletion of Kv4.2 gene eliminates dendritic A-type K+ current and enhances induction of long-term potentiation in hippocampal CA1 pyramidal neurons. J Neurosci. 2006 Nov 22; 26(47):12143-51. View Abstract
Search for excited and exotic muons in the mugamma decay channel in p-p collisions at sqrt s =1.96 TeV. Phys Rev Lett. 2006 Nov 10; 97(19):191802. View Abstract
Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events. Development. 2006 Dec; 133(23):4655-65. View Abstract
Search for large extra dimensions in the production of jets and missing transverse energy in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2006 Oct 27; 97(17):171802. View Abstract
Search for a neutral Higgs boson decaying to a W boson pair in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2006 Aug 25; 97(8):081802. View Abstract
Measurement of the tt production cross section in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2006 Aug 25; 97(8):082004. View Abstract
Measurement of the Bs0-Bs0 oscillation frequency. Phys Rev Lett. 2006 Aug 11; 97(6):062003. View Abstract
Assessing the potential role of photopheresis in hematopoietic stem cell transplant. Bone Marrow Transplant. 2006 Aug; 38(4):265-73. View Abstract
Search for new physics in lepton+photon+X events with 305 pb(-1) of pp collisions at [square root of s] = 1.96 TeV. Phys Rev Lett. 2006 Jul 21; 97(3):031801. View Abstract
Measurement of the Bc+ meson lifetime using the decay mode Bc+ --> J/Psie+nue. Phys Rev Lett. 2006 Jul 07; 97(1):012002. View Abstract
Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett. 2006 Jun 16; 96(23):231801. View Abstract
Search for Z' --> e+ e- using dielectron mass and angular distribution. Phys Rev Lett. 2006 Jun 02; 96(21):211801. View Abstract
Search for high-mass resonances decaying to emu in pp collisions at square root = 1.69 TeV. Phys Rev Lett. 2006 Jun 02; 96(21):211802. View Abstract
Direct search for Dirac magnetic monopoles in pp collisions at square root s = 1.96 TeV. Phys Rev Lett. 2006 May 26; 96(20):201801. View Abstract
Measurement of the tt production cross section in pp collisions at square root s = 1.96 TeV using missing E(T) + jets events with secondary vertex b tagging. Phys Rev Lett. 2006 May 26; 96(20):202002. View Abstract
Measurement of bottom-quark hadron masses in exclusive J/psi decays with the CDF detector. Phys Rev Lett. 2006 May 26; 96(20):202001. View Abstract
Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol. 2006 May 22; 173(4):545-57. View Abstract
Measurement of the ratios of branching fractions and. Phys Rev Lett. 2006 May 19; 96(19):191801. View Abstract
Search for scalar bottom quarks from gluino decays in collisions at. Phys Rev Lett. 2006 May 05; 96(17):171802. View Abstract
Top-quark mass measurement from dilepton events at CDF II. Phys Rev Lett. 2006 Apr 21; 96(15):152002. View Abstract
The kv4.2 potassium channel subunit is required for pain plasticity. Neuron. 2006 Apr 06; 50(1):89-100. View Abstract
Measurement of the inclusive jet cross section using the kT algorithm in pp collisions at (square root s)=1.96 TeV. Phys Rev Lett. 2006 Mar 31; 96(12):122001. View Abstract
Altered synaptic development and active zone spacing in endocytosis mutants. Curr Biol. 2006 Mar 21; 16(6):591-8. View Abstract
Measurement of the dipion mass spectrum in decays. Phys Rev Lett. 2006 Mar 17; 96(10):102002. View Abstract
Enhanced photocarcinogenesis in interleukin-12-deficient mice. Cancer Res. 2006 Mar 15; 66(6):2962-9. View Abstract
IL-18 reduces ultraviolet radiation-induced DNA damage and thereby affects photoimmunosuppression. J Immunol. 2006 Mar 01; 176(5):2896-901. View Abstract
Search for Higgs bosons decaying to bb and produced in association with W bosons in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2006 Mar 03; 96(8):081803. View Abstract
Evidence for the exclusive decay B(c)+- --> J/psi pi+- and measurement of the mass of the B(c)+- meson. Phys Rev Lett. 2006 Mar 03; 96(8):082002. View Abstract
The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development. Neuron. 2006 Feb 16; 49(4):517-31. View Abstract
Search for charged Higgs bosons from top quark decays in pp collisions at square root s=1.96 TeV. Phys Rev Lett. 2006 Feb 03; 96(4):042003. View Abstract
Precision top-quark mass measurement in the lepton+jets topology in p p collisions at square root s=1.96 TeV. Phys Rev Lett. 2006 Jan 20; 96(2):022004. View Abstract
Search for neutral Higgs bosons of the minimal supersymmetric standard model decaying to tau pairs in pp collisions at square root of s = 1.96 TeV. Phys Rev Lett. 2006 Jan 13; 96(1):011802. View Abstract
Transmitter release at the neuromuscular junction. Int Rev Neurobiol. 2006; 75:105-44. View Abstract
Search for new high-mass particles decaying to Lepton pairs in pp collisions at square root s = 1.96 TeV. Phys Rev Lett. 2005 Dec 16; 95(25):252001. View Abstract
Search for [corrected] B0(s) --> mu+ mu- and B0(d) [corrected] --> mu + mu- decays in pp collisions with CDF II. Phys Rev Lett. 2005 Nov 25; 95(22):221805. View Abstract
Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction. Circ Res. 2005 Dec 09; 97(12):1342-50. View Abstract
A slowed classical pathway rather than kiss-and-run mediates endocytosis at synapses lacking synaptojanin and endophilin. Cell. 2005 Nov 04; 123(3):521-33. View Abstract
Search for new physics using high-mass tau pairs from 1.96 TeV pp collisions. Phys Rev Lett. 2005 Sep 23; 95(13):131801. View Abstract
Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane. Dev Cell. 2005 Sep; 9(3):365-76. View Abstract
Measurement of B(t --> Wb)/B(t--> Wq) at the collider detector at fermilab. Phys Rev Lett. 2005 Sep 02; 95(10):102002. View Abstract
Search for long-lived doubly charged Higgs bosons in pp collisions at sqrt[s] = 1.96 TeV. Phys Rev Lett. 2005 Aug 12; 95(7):071801. View Abstract
Sec6 mutations and the Drosophila exocyst complex. J Cell Sci. 2005 Mar 15; 118(Pt 6):1139-50. View Abstract
Synaptotagmin promotes both vesicle fusion and recycling. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16401-2. View Abstract
Enhanced contact hypersensitivity and antiviral immune responses in vivo by keratinocyte-targeted overexpression of IL-15. Eur J Immunol. 2004 Jul; 34(7):2022-31. View Abstract
The exocyst component Sec5 is required for membrane traffic and polarity in the Drosophila ovary. Development. 2004 Jan; 131(2):377-88. View Abstract
Collagen metabolism is a novel target of the neuropeptide alpha-melanocyte-stimulating hormone. J Biol Chem. 2004 Feb 20; 279(8):6959-66. View Abstract
Mitochondria are redistributed in Drosophila photoreceptors lacking milton, a kinesin-associated protein. J Comp Neurol. 2003 Sep 01; 463(4):372-88. View Abstract
Mutations in the exocyst component Sec5 disrupt neuronal membrane traffic, but neurotransmitter release persists. Neuron. 2003 Feb 06; 37(3):433-47. View Abstract
Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron. 2002 Dec 19; 36(6):1063-77. View Abstract
Distribution of rSlo Ca2+-activated K+ channels in rat astrocyte perivascular endfeet. Brain Res. 2002 Nov 29; 956(2):183-93. View Abstract
Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13867-72. View Abstract
Synaptotagmins I and IV promote transmitter release independently of Ca(2+) binding in the C(2)A domain. Nature. 2002 Jul 18; 418(6895):336-40. View Abstract
Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair. Nat Cell Biol. 2002 Jan; 4(1):26-31. View Abstract
Genetic manipulation of cardiac K(+) channel function in mice: what have we learned, and where do we go from here? Circ Res. 2001 Nov 23; 89(11):944-56. View Abstract
Absence of junctional glutamate receptor clusters in Drosophila mutants lacking spontaneous transmitter release. Science. 2001 Jul 20; 293(5529):514-7. View Abstract
The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes. J Physiol. 2001 Jun 15; 533(Pt 3):697-710. View Abstract
Intracellular persistence of Staphylococcus aureus small-colony variants within keratinocytes: a cause for antibiotic treatment failure in a patient with darier's disease. Clin Infect Dis. 2001 Jun 01; 32(11):1643-7. View Abstract
Inhibition of growth of melanoma cells by CD95 (Fas/APO-1) gene transfer in vivo. J Invest Dermatol. 2000 Dec; 115(6):1008-14. View Abstract
SNAP-24, a Drosophila SNAP-25 homologue on granule membranes, is a putative mediator of secretion and granule-granule fusion in salivary glands. J Cell Sci. 2000 Nov; 113 ( Pt 22):4055-64. View Abstract
Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation. Circ Res. 2000 Jul 21; 87(2):160-6. View Abstract
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell. 2000 Jun; 5(6):969-79. View Abstract
NSF is up to new tricks. Nat Cell Biol. 1999 Oct; 1(6):E141-3. View Abstract
Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell. 1999 Sep 03; 98(5):585-95. View Abstract
A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. Genetics. 1999 Aug; 152(4):1631-9. View Abstract
Transfection of immature murine bone marrow-derived dendritic cells with the granulocyte-macrophage colony-stimulating factor gene potently enhances their in vivo antigen-presenting capacity. J Immunol. 1999 Jul 01; 163(1):174-83. View Abstract
Identification and localization of Ca(2+)-activated K+ channels in rat sciatic nerve. Glia. 1999 Apr; 26(2):166-75. View Abstract
Selective effects of neuronal-synaptobrevin mutations on transmitter release evoked by sustained versus transient Ca2+ increases and by cAMP. J Neurosci. 1999 Apr 01; 19(7):2432-41. View Abstract
Genetic evidence for an equilibrium between docked and undocked vesicles. Philos Trans R Soc Lond B Biol Sci. 1999 Feb 28; 354(1381):299-306. View Abstract
Dynamic potassium channel distributions during axonal development prevent aberrant firing patterns. J Neurosci. 1999 Jan 15; 19(2):747-58. View Abstract
Morphologically docked synaptic vesicles are reduced in synaptotagmin mutants of Drosophila. J Neurosci. 1998 Oct 01; 18(19):7662-73. View Abstract
Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-synaptobrevin. J Neurosci. 1998 Mar 15; 18(6):2028-39. View Abstract
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J Cell Biol. 1998 Jan 12; 140(1):171-82. View Abstract
Potassium channel distribution, clustering, and function in remyelinating rat axons. J Neurosci. 1998 Jan 01; 18(1):36-47. View Abstract
The synaptic protein syntaxin1 is required for cellularization of Drosophila embryos. J Cell Biol. 1997 Aug 25; 138(4):861-75. View Abstract
Complex gene organization of synaptic protein SNAP-25 in Drosophila melanogaster. Gene. 1997 Jul 31; 194(2):169-77. View Abstract
Anomalous mole fraction effect induced by mutation of the H5 pore region in the Shaker K+ channel. Biophys J. 1996 Nov; 71(5):2467-72. View Abstract
Inwardly rectifying K+ channels that may participate in K+ buffering are localized in microvilli of Schwann cells. J Neurosci. 1996 Apr 15; 16(8):2421-9. View Abstract
Inhibition of the Kv4 (Shal) family of transient K+ currents by arachidonic acid. J Neurosci. 1996 Apr 15; 16(8):2522-32. View Abstract
Inhibition of the Kv4 (Shal) family of transient K+ currents by arachidonic acid. J Neurosci. 1996 Feb 01; 16(3):1016-25. View Abstract
Differential distribution of closely related potassium channels in rat Schwann cells. J Neurosci. 1995 May; 15(5 Pt 2):3761-74. View Abstract
Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. Evidence for increased cell viability and suppression of cytokine release. J Clin Invest. 1995 Mar; 95(3):926-33. View Abstract
Drosophila genetics and the functions of synaptic proteins. Cold Spring Harb Symp Quant Biol. 1995; 60:371-7. View Abstract
Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10727-31. View Abstract
Genetic analysis of neurotransmitter release at the synapse. Curr Opin Neurobiol. 1994 Oct; 4(5):633-9. View Abstract
The effect on synaptic physiology of synaptotagmin mutations in Drosophila. Neuron. 1994 Apr; 12(4):909-20. View Abstract
Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology. 1993 Nov; 32(11):1075-88. View Abstract
Identification and characterization of Drosophila genes for synaptic vesicle proteins. J Neurosci. 1993 Nov; 13(11):4924-35. View Abstract
Differential expression of transcripts from syb, a Drosophila melanogaster gene encoding VAMP (synaptobrevin) that is abundant in non-neuronal cells. Gene. 1993 Sep 15; 131(2):175-81. View Abstract
Synaptic transmission persists in synaptotagmin mutants of Drosophila. Cell. 1993 Jul 02; 73(7):1281-90. View Abstract
Functional expression of a rapidly inactivating neuronal calcium channel. Nature. 1993 Jun 03; 363(6428):455-8. View Abstract
Molecular diversity of Ca2+ channel alpha 1 subunits from the marine ray Discopyge ommata. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):3787-91. View Abstract
Alteration of ionic selectivity of a K+ channel by mutation of the H5 region. Nature. 1991 Feb 21; 349(6311):700-4. View Abstract
Immunological characterization of K+ channel components from the Shaker locus and differential distribution of splicing variants in Drosophila. Neuron. 1990 Jan; 4(1):119-27. View Abstract
A Dictyostelium mutant with severe defects in alpha-actinin: its characterization using cDNA probes and monoclonal antibodies. J Cell Sci. 1988 May; 90 ( Pt 1):59-71. View Abstract
Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes. Nature. 1988 Jan 14; 331(6152):143-5. View Abstract
Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature. 1988 Jan 14; 331(6152):137-42. View Abstract
Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science. 1987 Aug 14; 237(4816):749-53. View Abstract
Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science. 1987 Aug 14; 237(4816):770-5. View Abstract
Proctolin in the lobster nervous system. Peptides. 1985; 6 Suppl 3:393-402. View Abstract
Proctolin in the lobster: the distribution, release, and chemical characterization of a likely neurohormone. J Neurosci. 1984 May; 4(5):1300-11. View Abstract
Serotonin-induced protein phosphorylation in a lobster neuromuscular preparation. J Neurosci. 1984 Mar; 4(3):611-26. View Abstract
Amines and a peptide as neurohormones in lobsters: actions on neuromuscular preparations and preliminary behavioural studies. J Exp Biol. 1980 Dec; 89:159-75. View Abstract
A peptide action in a lobster neuromuscular preparation. J Neurobiol. 1980 Nov; 11(6):623-8. View Abstract