Peter Nigrovic

Publications

1. Early transcriptional effects of inflammatory cytokines reveal highly redundant cytokine networks. J Exp Med. 2025 Apr 07; 222(4). View Abstract
2. The 'Treg paradox' in inflammatory arthritis. Nat Rev Rheumatol. 2025 Jan; 21(1):9-21. View Abstract
3. Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. J Allergy Clin Immunol. 2024 Nov 30. View Abstract
4. Sex-specific NLRP3 activation in neutrophils promotes neutrophil recruitment and NETosis in the murine model of diffuse alveolar hemorrhage. Front Immunol. 2024; 15:1466234. View Abstract
5. EULAR/PReS recommendations for the diagnosis and management of Still's disease, comprising systemic juvenile idiopathic arthritis and adult-onset Still's disease. Ann Rheum Dis. 2024 Nov 14; 83(12):1614-1627. View Abstract
6. Macrophage Activation Syndrome. Arthritis Rheumatol. 2024 Nov 03. View Abstract
7. Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis. HGG Adv. 2025 Jan 09; 6(1):100375. View Abstract
8. Regional specialization within the mammalian respiratory immune system. Trends Immunol. 2024 Nov; 45(11):871-891. View Abstract
9. Classification Criteria for Axial Disease in Youth With Juvenile Spondyloarthritis. Arthritis Rheumatol. 2024 Dec; 76(12):1797-1808. View Abstract
10. High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. Nat Commun. 2024 Aug 09; 15(1):6804. View Abstract
11. Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. Semin Arthritis Rheum. 2024 Oct; 68:152516. View Abstract
12. Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Pediatr Rheumatol Online J. 2024 Jul 10; 22(1):64. View Abstract
13. Functional genomics implicates natural killer cells in the pathogenesis of ankylosing spondylitis. medRxiv. 2024 May 09. View Abstract
14. High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus. bioRxiv. 2024 Apr 12. View Abstract
15. Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis. Nat Rev Rheumatol. 2024 May; 20(5):258-271. View Abstract
16. "Rounding Third Base and Heading Home": Arthritis & Rheumatology in 2024. Arthritis Rheumatol. 2024 Jun; 76(6):819-822. View Abstract
17. Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development. Nat Commun. 2024 Mar 09; 15(1):2150. View Abstract
18. Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant. Cell Genom. 2024 Feb 14; 4(2):100502. View Abstract
19. Recent advances and evolving concepts in Still's disease. Nat Rev Rheumatol. 2024 Feb; 20(2):116-132. View Abstract
20. The 4th NextGen Therapies for SJIA and MAS: part 1 the elephant in the room: diagnostic/classification criteria for systemic juvenile idiopathic arthritis and adult-onset still's disease. Pediatr Rheumatol Online J. 2024 Jan 05; 21(Suppl 1):114. View Abstract
21. Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework. Res Sq. 2023 Dec 12. View Abstract
22. Human and mouse neutrophils share core transcriptional programs in both homeostatic and inflamed contexts. Nat Commun. 2023 Dec 08; 14(1):8133. View Abstract
23. Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders. Arthritis Rheumatol. 2024 02; 76(2):285-292. View Abstract
24. Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. J Clin Invest. 2023 11 15; 133(22). View Abstract
25. Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant. Cell Genom. 2023 Nov 08; 3(11):100420. View Abstract
26. Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis. ACR Open Rheumatol. 2023 Oct; 5(10):556-562. View Abstract
27. NLRP3 is essential for neutrophil polarization and chemotaxis in response to leukotriene B4 gradient. Proc Natl Acad Sci U S A. 2023 08 29; 120(35):e2303814120. View Abstract
28. Therapeutic Development in Polyarticular Course Juvenile Idiopathic Arthritis: Extrapolation, Dose Selection, and Clinical Trial Design. Arthritis Rheumatol. 2023 10; 75(10):1856-1866. View Abstract
29. Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2023 10; 75(10):2063-2072. View Abstract
30. Comparison of disease phenotypes and mechanistic insight on causal variants in patients with DADA2. J Allergy Clin Immunol. 2023 09; 152(3):771-782. View Abstract
31. Biologics and JAK inhibitors for the treatment of monogenic systemic autoinflammatory diseases in children. J Allergy Clin Immunol. 2023 03; 151(3):607-618. View Abstract
32. Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. Front Immunol. 2022; 13:1068399. View Abstract
33. First-line options for systemic juvenile idiopathic arthritis treatment: an observational study of Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans. Pediatr Rheumatol Online J. 2022 Dec 08; 20(1):113. View Abstract
34. mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Nat Commun. 2022 11 28; 13(1):6915. View Abstract
35. Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. Arthritis Rheumatol. 2022 11; 74(11):1851-1858. View Abstract
36. VEXAS Syndrome and Disease Taxonomy in Rheumatology. Arthritis Rheumatol. 2022 11; 74(11):1733-1736. View Abstract
37. TET2-mutant clonal hematopoiesis and risk of gout. Blood. 2022 09 08; 140(10):1094-1103. View Abstract
38. Correction: Stoll et al. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children 2022, 9, 569. Children (Basel). 2022 Aug 02; 9(8). View Abstract
39. An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. J Rheumatol. 2022 Sep; 49(9):1042-1051. View Abstract
40. The Conundrum of Lung Disease and Drug Hypersensitivity-like Reactions in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2022 07; 74(7):1122-1131. View Abstract
41. Arthritis & Rheumatology: "Mid-Term" Report. Arthritis Rheumatol. 2022 07; 74(7):1099-1101. View Abstract
42. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children (Basel). 2022 Apr 16; 9(4). View Abstract
43. Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis. Blood Adv. 2022 04 12; 6(7):2081-2091. View Abstract
44. Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis. Paediatr Drugs. 2022 May; 24(3):185-191. View Abstract
45. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Arthritis Rheumatol. 2022 04; 74(4):570-585. View Abstract
46. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2022 04; 74(4):521-537. View Abstract
47. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Arthritis Care Res (Hoboken). 2022 04; 74(4):505-520. View Abstract
48. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2022 04; 74(4):553-569. View Abstract
49. Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint. Ann Rheum Dis. 2022 06; 81(6):805-814. View Abstract
50. Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2022 Jan 15; 20(1):3. View Abstract
51. Weekly Adalimumab, an Effective Alternative for Refractory Uveitis in Children. J Clin Rheumatol. 2022 Jan 01; 28(1):e301-e304. View Abstract
52. Arthritis flares mediated by tissue-resident memory T cells in the joint. Cell Rep. 2021 10 26; 37(4):109902. View Abstract
53. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. JCI Insight. 2021 09 22; 6(18). View Abstract
54. IL-1ß-driven osteoclastogenic Tregs accelerate bone erosion in arthritis. J Clin Invest. 2021 09 15; 131(18). View Abstract
55. Serologic Response to Borrelia Antigens Varies with Clinical Phenotype in Children and Young Adults with Lyme Disease. J Clin Microbiol. 2021 10 19; 59(11):e0134421. View Abstract
56. Genome editing to define the function of risk loci and variants in rheumatic disease. Nat Rev Rheumatol. 2021 08; 17(8):462-474. View Abstract
57. A multidisciplinary assessment of pain in juvenile idiopathic arthritis. Semin Arthritis Rheum. 2021 08; 51(4):700-711. View Abstract
58. Effects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism. Front Immunol. 2021; 12:680227. View Abstract
59. Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. Nat Immunol. 2021 06; 22(6):711-722. View Abstract
60. The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments. Nat Commun. 2021 05 17; 12(1):2856. View Abstract
61. Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach. J Allergy Clin Immunol. 2022 01; 149(1):379-387. View Abstract
62. Publisher Correction: Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nat Rev Rheumatol. 2021 May; 17(5):306. View Abstract
63. A Picture Is Worth a Thousand Words, But Only If It Is a Good Picture. Arthritis Rheumatol. 2021 06; 73(6):912-913. View Abstract
64. Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nat Rev Rheumatol. 2021 05; 17(5):257-269. View Abstract
65. Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. PLoS One. 2021; 16(1):e0244187. View Abstract
66. Estrogen-Driven Changes in Immunoglobulin G Fc Glycosylation. Exp Suppl. 2021; 112:341-361. View Abstract
67. Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience. J Card Surg. 2021 Feb; 36(2):735-738. View Abstract
68. COVID-19 cytokine storm: what is in a name? Ann Rheum Dis. 2021 01; 80(1):3-5. View Abstract
69. Reply. Arthritis Rheumatol. 2021 01; 73(1):176-178. View Abstract
70. Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. J Clin Invest. 2020 11 02; 130(11):5942-5950. View Abstract
71. Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach. J Allergy Clin Immunol. 2020 11; 146(5):925-937. View Abstract
72. Effects of estradiol on biological age measured using the glycan age index. Aging (Albany NY). 2020 Oct 13; 12(19):19756-19765. View Abstract
73. The "Infodemic" of COVID-19. Arthritis Rheumatol. 2020 11; 72(11):1806-1808. View Abstract
74. NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus. Arthritis Rheumatol. 2020 10; 72(10):1707-1720. View Abstract
75. Arthritis & Rheumatology: Evolving to Meet the Challenges of Rheumatology. Arthritis Rheumatol. 2020 08; 72(8):1254-1255. View Abstract
76. The Fyn-Stat5 cascade is required for Fc? receptor-mediated mast cell function. Cell Immunol. 2020 10; 356:104134. View Abstract
77. Identification of Prevotella Oralis as a possible target antigen in children with Enthesitis related arthritis. Clin Immunol. 2020 07; 216:108463. View Abstract
78. On the Alert for Cytokine Storm: Immunopathology in COVID-19. Arthritis Rheumatol. 2020 07; 72(7):1059-1063. View Abstract
79. Polyarteritis nodosa and deficiency of adenosine deaminase 2 - Shared genealogy, generations apart. Clin Immunol. 2020 06; 215:108411. View Abstract
80. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 03 26; 5(6). View Abstract
81. Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. J Biol Chem. 2020 04 24; 295(17):5761-5770. View Abstract
82. Response to: 'Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum' by Gao et al. Ann Rheum Dis. 2022 02; 81(2):e31. View Abstract
83. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). J Allergy Clin Immunol. 2020 06; 145(6):1664-1672.e10. View Abstract
84. Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon. Arthritis Rheumatol. 2020 01; 72(1):100-113. View Abstract
85. Megakaryocyte emperipolesis: a new frontier in cell-in-cell interaction. Platelets. 2020 Aug 17; 31(6):700-706. View Abstract
86. Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Ann Rheum Dis. 2020 02; 79(2):225-231. View Abstract
87. IgG Fc glycosylation as an axis of humoral immunity in childhood. J Allergy Clin Immunol. 2020 02; 145(2):710-713.e9. View Abstract
88. PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20). View Abstract
89. SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20635-20643. View Abstract
90. Storm Warning: Lung Disease in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2019 11; 71(11):1773-1775. View Abstract
91. Implications of juvenile idiopathic arthritis genetic risk variants for disease pathogenesis and classification. Curr Opin Rheumatol. 2019 09; 31(5):401-410. View Abstract
92. Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Nat Commun. 2019 08 21; 10(1):3765. View Abstract
93. High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. JCI Insight. 2019 08 08; 4(15). View Abstract
94. Increased ILC3s associated with higher levels of IL-1ß aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase. Eur J Immunol. 2019 11; 49(11):2063-2073. View Abstract
95. A role for G protein-coupled receptor 137b in bone remodeling in mouse and zebrafish. Bone. 2019 10; 127:104-113. View Abstract
96. ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-?B via phosphoinosotide remodeling of endosomes. Nat Commun. 2019 05 21; 10(1):2247. View Abstract
97. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. Elife. 2019 05 01; 8. View Abstract
98. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Arthritis Rheumatol. 2019 06; 71(6):864-877. View Abstract
99. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Arthritis Care Res (Hoboken). 2019 06; 71(6):717-734. View Abstract
100. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Arthritis Rheumatol. 2019 06; 71(6):846-863. View Abstract
101. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Arthritis Care Res (Hoboken). 2019 06; 71(6):703-716. View Abstract
102. Antibody-dependent and -independent mechanisms of inflammatory arthritis. JCI Insight. 2019 03 07; 4(5). View Abstract
103. Neutrophil Heterogeneity as Therapeutic Opportunity in Immune-Mediated Disease. Front Immunol. 2019; 10:346. View Abstract
104. Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. Pediatr Rheumatol Online J. 2019 Feb 14; 17(1):7. View Abstract
105. Differential attenuation of ß2 integrin-dependent and -independent neutrophil migration by Ly6G ligation. Blood Adv. 2019 02 12; 3(3):256-267. View Abstract
106. The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses. PLoS One. 2019; 14(2):e0211943. View Abstract
107. Juvenile Idiopathic Arthritis: An Idea Whose Time Has Gone? J Rheumatol. 2019 02; 46(2):124-126. View Abstract
108. Megakaryocytes as immune cells. J Leukoc Biol. 2019 06; 105(6):1111-1121. View Abstract
109. Maestro endothelium conducts the neutrophils. Blood. 2018 10 25; 132(17):1734-1735. View Abstract
110. Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nat Genet. 2018 10; 50(10):1366-1374. View Abstract
111. High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Nat Genet. 2018 08; 50(8):1180-1188. View Abstract
112. Editorial: Toward Personalized Treatment for Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2018 08; 70(8):1172-1174. View Abstract
113. Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2. J Allergy Clin Immunol. 2018 10; 142(4):1363-1365.e8. View Abstract
114. Hip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic Area. Pediatrics. 2018 05; 141(5). View Abstract
115. The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases. Arthritis Rheumatol. 2018 05; 70(5):669-678. View Abstract
116. Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST). Clin Trials. 2018 06; 15(3):268-277. View Abstract
117. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nat Commun. 2018 02 23; 9(1):789. View Abstract
118. Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program. Arthritis Care Res (Hoboken). 2018 03; 70(3):445-453. View Abstract
119. Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Arthritis Res Ther. 2018 01 30; 20(1):14. View Abstract
120. Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2018 03; 70(3):409-419. View Abstract
121. Mycobacterial infection induces higher interleukin-1ß and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase. PLoS One. 2017; 12(12):e0189453. View Abstract
122. High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis. Glycobiology. 2017 12 01; 27(12):1099-1108. View Abstract
123. Review: Genetics and the Classification of Arthritis in Adults and Children. Arthritis Rheumatol. 2018 01; 70(1):7-17. View Abstract
124. Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. Arthritis Rheumatol. 2017 11; 69(11):2222-2232. View Abstract
125. Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate. Rheumatology (Oxford). 2017 09 01; 56(9):1542-1551. View Abstract
126. CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation. Blood. 2017 11 09; 130(19):2092-2100. View Abstract
127. The metabolic regulator mTORC1 controls terminal myeloid differentiation. Sci Immunol. 2017 May 26; 2(11). View Abstract
128. Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans. Pediatr Rheumatol Online J. 2017 Apr 11; 15(1):23. View Abstract
129. Megakaryocytes compensate for Kit insufficiency in murine arthritis. J Clin Invest. 2017 May 01; 127(5):1714-1724. View Abstract
130. Building an ARC to Grant Success: The Aims Review Committee. Arthritis Care Res (Hoboken). 2017 04; 69(4):459-461. View Abstract
131. Estrogens regulate glycosylation of IgG in women and men. JCI Insight. 2017 02 23; 2(4):e89703. View Abstract
132. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017 02 01; 542(7639):110-114. View Abstract
133. Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. Ann Rheum Dis. 2017 04; 76(4):765-772. View Abstract
134. Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Sci Transl Med. 2016 12 14; 8(369):369ra176. View Abstract
135. Frequency and Morbidity of Temporomandibular Joint Involvement in Adult Patients With a History of Juvenile Idiopathic Arthritis. J Oral Maxillofac Surg. 2017 Jun; 75(6):1191-1200. View Abstract
136. Quantifying Temporomandibular Joint Synovitis in Children With Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2016 12; 68(12):1795-1802. View Abstract
137. Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses. Sci Rep. 2016 10 27; 6:35928. View Abstract
138. The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1. PLoS Genet. 2016 09; 12(9):e1006292. View Abstract
139. Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2016 07; 68(7):1758-68. View Abstract
140. Efficacy of an Interinstitutional Mentoring Program Within Pediatric Rheumatology. Arthritis Care Res (Hoboken). 2016 05; 68(5):645-51. View Abstract
141. Editorial: 21st Century Storm Chasers: Defining Macrophage Activation Syndrome. Arthritis Rheumatol. 2016 Mar; 68(3):557-60. View Abstract
142. Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis. Ann Rheum Dis. 2016 Nov; 75(11):2022-2028. View Abstract
143. Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis. Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):15785-6. View Abstract
144. Increased pretreatment serum IFN-ß/a ratio predicts non-response to tumour necrosis factor a inhibition in rheumatoid arthritis. Ann Rheum Dis. 2016 10; 75(10):1757-62. View Abstract
145. MICL controls inflammation in rheumatoid arthritis. Ann Rheum Dis. 2016 07; 75(7):1386-91. View Abstract
146. Redox Regulation of Pro-IL-1ß Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice. Antioxid Redox Signal. 2015 Oct 20; 23(12):973-84. View Abstract
147. Inhibition of inflammatory arthritis using fullerene nanomaterials. PLoS One. 2015; 10(4):e0126290. View Abstract
148. Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity. Pediatr Rheumatol Online J. 2015; 13:7. View Abstract
149. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment. PLoS One. 2015; 10(1):e0116812. View Abstract
150. Evaluation of synovial mast cell functions in autoimmune arthritis. Methods Mol Biol. 2015; 1220:423-42. View Abstract
151. Reply: To PMID 24623686. Arthritis Rheumatol. 2014 Sep; 66(9):2645-6. View Abstract
152. Adding canakinumab to the Childhood Arthritis and Rheumatology Research Alliance consensus treatment plans for systemic juvenile idiopathic arthritis: Comment on the article by DeWitt et al. Arthritis Care Res (Hoboken). 2014 Sep; 66(9):1430-1. View Abstract
153. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood. 2014 Oct 02; 124(14):2173-83. View Abstract
154. Highly parallel characterization of IgG Fc binding interactions. MAbs. 2014 Jul-Aug; 6(4):915-27. View Abstract
155. IL-33/ST2 axis promotes mast cell survival via BCLXL. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10281-6. View Abstract
156. Review: is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis? Arthritis Rheumatol. 2014 Jun; 66(6):1405-13. View Abstract
157. Choosing Wisely: the American College of Rheumatology's Top 5 for pediatric rheumatology. Arthritis Care Res (Hoboken). 2014 May; 66(5):649-57. View Abstract
158. A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S156. View Abstract
159. A161: Novel 3-Dimensional Explant Method Facilitates the Study of Lymphocyte Populations in the Synovium and Reveals a Large Population of Resident Memory T cells in Rheumatoid Arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S209. View Abstract
160. A177: Program Evaluation of the ACR/CARRA Inter-Institutional Mentoring Program (AMIGO) in Pediatric Rheumatology. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S231. View Abstract
161. AMIGO: a novel approach to the mentorship gap in pediatric rheumatology. J Pediatr. 2014 Feb; 164(2):226-7.e1-3. View Abstract
162. Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Hum Mol Genet. 2014 Jun 01; 23(11):2880-7. View Abstract
163. Synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas. Pediatr Emerg Care. 2014 Jan; 30(1):16-9. View Abstract
164. Transition and transfer of adolescents and young adults with pediatric onset chronic disease: the patient and parent perspective. J Pediatr Rehabil Med. 2014; 7(1):43-51. View Abstract
165. Dr. Henderson, et al reply. J Rheumatol. 2013 Nov; 40(11):1926. View Abstract
166. Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Sci Transl Med. 2013 Oct 30; 5(209):209ra150. View Abstract
167. Sweets are good for you: fine tuning antibodies via glycosylation. Arthritis Rheum. 2013 Oct; 65(10):2541-4. View Abstract
168. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Care Res (Hoboken). 2013 Oct; 65(10):1551-63. View Abstract
169. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Rheum. 2013 Oct; 65(10):2499-512. View Abstract
170. Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet. 2013 Jun; 45(6):664-9. View Abstract
171. Race, ethnicity, and disease outcomes in juvenile idiopathic arthritis: a cross-sectional analysis of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. J Rheumatol. 2013 Jun; 40(6):936-42. View Abstract
172. Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. J Clin Invest. 2013 May; 123(5):2183-92. View Abstract
173. Ly6 family proteins in neutrophil biology. J Leukoc Biol. 2013 Oct; 94(4):585-94. View Abstract
174. PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. J Autoimmun. 2013 Jun; 43:1-9. View Abstract
175. Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. J Rheumatol. 2013 Mar; 40(3):273-81. View Abstract
176. Ly6G: a work in progress--author's reply to Yipp. Blood. 2013 Jan 03; 121(1):242-3. View Abstract
177. The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. EMBO Mol Med. 2013 Feb; 5(2):235-49. View Abstract
178. Characterization of fibrinogen glycosylation and its importance for serum/plasma N-glycome analysis. J Proteome Res. 2013 Jan 04; 12(1):444-54. View Abstract
179. Interleukin-33 primes mast cells for activation by IgG immune complexes. PLoS One. 2012; 7(10):e47252. View Abstract
180. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33. View Abstract
181. Platelets: active players in the pathogenesis of arthritis and SLE. Nat Rev Rheumatol. 2012 Sep; 8(9):534-42. View Abstract
182. Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2012 Jul; 64(7):1001-10. View Abstract
183. Ly6G ligation blocks recruitment of neutrophils via a ß2-integrin-dependent mechanism. Blood. 2012 Aug 16; 120(7):1489-98. View Abstract
184. Platelets can enhance vascular permeability. Blood. 2012 Aug 09; 120(6):1334-43. View Abstract
185. Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis. J Biol Chem. 2012 Jun 08; 287(24):20047-55. View Abstract
186. Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis. Arthritis Res Ther. 2012 Mar 05; 14(2):R43. View Abstract
187. Clinical comparison of early-onset psoriatic and non-psoriatic oligoarticular juvenile idiopathic arthritis. Clin Exp Rheumatol. 2011 May-Jun; 29(3):582-8. View Abstract
188. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum. 2011 Feb; 63(2):545-55. View Abstract
189. C5a receptor enables participation of mast cells in immune complex arthritis independently of Fc? receptor modulation. Arthritis Rheum. 2010 Nov; 62(11):3322-33. View Abstract
190. Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1). J Biol Chem. 2010 Jul 09; 285(28):21478-86. View Abstract
191. Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis Rheum. 2010 Mar; 62(3):753-64. View Abstract
192. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science. 2010 Jan 29; 327(5965):580-3. View Abstract
193. Juvenile psoriatic arthritis: bathwater or baby? J Rheumatol. 2009 Sep; 36(9):1861-3. View Abstract
194. Mast cells contribute to autoimmune inflammatory arthritis via their tryptase/heparin complexes. J Immunol. 2009 Jan 01; 182(1):647-56. View Abstract
195. Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy. Am J Pathol. 2008 Dec; 173(6):1693-701. View Abstract
196. Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis Rheum. 2008 May; 58(5):1354-65. View Abstract
197. Comparison of Vancouver and International League of Associations for rheumatology classification criteria for juvenile psoriatic arthritis. Arthritis Rheum. 2008 Jan 15; 59(1):51-8. View Abstract
198. Overview of hip pain in childhood. 2008. View Abstract
199. Tumor necrosis factor receptor-1 associated periodic syndrome (TRAPS). 2008. View Abstract
200. Evaluation of the child with back pain. 2008. View Abstract
201. Overview of the causes of back pain in children and adolescents. 2008. View Abstract
202. Mast cells. Rheumatoid Arthritis. Hochberg MC, Silman AJ, Smolen JS, Weisman MH, Weinblatt ME (in press). 2008. View Abstract
203. Periodic fever syndromes and other autoinflammatory diseases: An overview. 2008. View Abstract
204. Hemarthrosis. 2008. View Abstract
205. Mast cells. Kelley's Textbook of Rheumatology. Firestein GS, Budd RC, Harris ED, McInnes IB, Ruddy S, Sergent JS (in press). 2008; in press. View Abstract
206. Mast cells contribute to autoimmune inflammatory arthritis via tryptase•heparin complexes . (submitted). 2008. View Abstract
207. Laboratory and imaging studies in rheumatology. Rudolph's Pediatrics. (in press). 2008. View Abstract
208. Synovial mast cells: role in acute and chronic arthritis. Immunol Rev. 2007 Jun; 217:19-37. View Abstract
209. Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2325-30. View Abstract
210. Mast cells in acute and chronic inflammatory arthritis. Immunol Rev. 2007; 217:19-37. View Abstract
211. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum. 2006 Nov; 54(11):3564-72. View Abstract
212. Subpopulations within juvenile psoriatic arthritis: a review of the literature. Clin Dev Immunol. 2006 Jun-Dec; 13(2-4):377-80. View Abstract
213. Extreme thrombocytosis predicts Kawasaki disease in infants. Clin Pediatr (Phila). 2006 Jun; 45(5):446-52. View Abstract
214. Care of the adult with juvenile rheumatoid arthritis. Arthritis Rheum. 2006 Apr 15; 55(2):208-16. View Abstract
215. Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. J Exp Med. 2006 Apr 17; 203(4):837-42. View Abstract
216. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006 Mar; 7(3):284-92. View Abstract
217. Innate immunity and immune complexes in rheumatoid arthritis. Rheumatoid Arthritis: New Frontiers in Pathogenesis and Treatment, G.S. Firestein, G.S. Panayi, F.A. Wollheim (eds.). 2006. View Abstract
218. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005 Jul; 116(1):e89-93. View Abstract
219. Mast cells in autoantibody responses and arthritis. Novartis Found Symp. 2005; 271:200-9; discussion 210-4. View Abstract
220. Anti-inflammatory and immunomodulatory therapy. Comprehensive Pediatrics, Osborn LM, DeWitt TG, First LR, Zenel JA (eds). 2005. View Abstract
221. Mast cells in inflammatory arthritis. Arthritis Res Ther. 2005; 7(1):1-11. View Abstract
222. Raynaud's phenomenon in children: a retrospective review of 123 patients. Pediatrics. 2003 Apr; 111(4 Pt 1):715-21. View Abstract
223. Spanish for Pediatric Medicine. 2003. View Abstract
224. Kawasaki syndrome and acquired heart disease. J Musculoskel Med. 2002; 19:65-75. View Abstract
225. Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. Mayo Clin Proc. 2002 Jan; 77(1):92-6. View Abstract
226. Treatment of TRAPS with etanercept: use in pediatrics. Clin Exp Rheumatol. 2001 Jul-Aug; 19(4):484-5. View Abstract
227. Treatment of allergic asthma with monoclonal anti-IgE antibody. Pediatrics. 2001; 108:S566-567. View Abstract
228. Tuberculosis in Los Lomas Zaragoza, Chimaltenango. 1994. View Abstract
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