Research Overview

Pedro del Nido's basic research is directed at understanding the metabolic and structural changes due to left ventricular hypertrophy. His clinical goal is to apply minimally invasive robotic surgery and other cutting-edge techniques to enhance cardiac surgery. 

Research Background

Dr. del Nido received his MD degree from the University of Wisconsin Medical School. He completed his training at Boston University Medical Center, Toronto General Hospital, and the Hospital for Sick Children in Toronto.

Education

Medical School

University of Wisconsin Medical School
1977 Madison WI

Residency

General Surgery Boston University
1982 Boston MA

Residency

Cardiothoracic Surgery Toronto General Hospital
1985 Toronto Canada

Fellowship

Pediatric Cardiothoracic Surgery Hospital for Sick Children
1986 Toronto Canada

Media

Innovation

20 Years of Innovating the Biventricular Repair

Publications

  1. Mitochondrial transplantation normalizes transcriptomic and proteomic shift associated with ischemia reperfusion injury in neonatal hearts donated after circulatory death. Sci Rep. 2024 12 28; 14(1):31236. View Abstract
  2. Cross-species analyses of thymic mimetic cells reveal evolutionarily ancient origins and both conserved and species-specific elements. Immunity. 2025 01 14; 58(1):108-123.e7. View Abstract
  3. Biventricular Repair of Univentricular Heart Lowers Risk of Liver Disease Compared With the Fontan Operation. JACC Adv. 2025 Jan; 4(1):101429. View Abstract
  4. Challenges in the Development and Evaluation of Pediatric Heart Valve Technologies. Ann Thorac Surg. 2024 Dec 12. View Abstract
  5. Intraoperative Conduction Mapping to Reduce Postoperative Atrioventricular Block in Complex Congenital Heart Disease. J Am Coll Cardiol. 2024 Nov 19; 84(21):2102-2112. View Abstract
  6. Biomechanics and clinical implications of Fontan upsizing. Comput Biol Med. 2024 Dec; 183:109317. View Abstract
  7. Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC. Lancet Child Adolesc Health. 2024 Oct; 8(10):773-780. View Abstract
  8. Ventricular septation for double inlet ventricle: Avoiding conduction injury. J Thorac Cardiovasc Surg. 2024 Sep 26. View Abstract
  9. Challenges and Priorities for Children With Congenital Valvar Heart Disease: The Heart Valve Collaboratory. JACC Adv. 2024 Oct; 3(10):101191. View Abstract
  10. Reverse double switch operation for the borderline left ventricle. J Thorac Cardiovasc Surg. 2024 Aug 31. View Abstract
  11. Predictive modeling of endocardial fibroelastosis recurrence in patients with congenital heart disease. J Thorac Cardiovasc Surg. 2025 Feb; 169(2):366-374. View Abstract
  12. Impact of permanent pacemaker for iatrogenic atrioventricular block on outcomes after congenital heart surgery. J Thorac Cardiovasc Surg. 2025 Feb; 169(2):411-419.e5. View Abstract
  13. Congenital Heart Surgery: In Rapid Evolution. Circulation. 2024 Aug 20; 150(8):583-585. View Abstract
  14. Clinical and 2D/3D-Echo Cardiography Determinants of Mitral Valve Reoperation in Children With Congenital Mitral Valve Disease. JACC Adv. 2024 Aug; 3(8):101081. View Abstract
  15. Experience Curve With the Cone Procedure for Ebstein's Anomaly: Effect on Cost and Resource Utilization. JACC Adv. 2024 Aug; 3(8):101104. View Abstract
  16. Intraoperative conduction system mapping during reoperative mitral valve replacement. JTCVS Tech. 2024 Oct; 27:138-141. View Abstract
  17. Multiphysiologic State Computational Fluid Dynamics Modeling for Planning Fontan With Interrupted Inferior Vena Cava. JACC Adv. 2024 Jul; 3(7):101057. View Abstract
  18. Surgical debulking of large ventricular fibromas in children. J Thorac Cardiovasc Surg. 2025 Jan; 169(1):186-194. View Abstract
  19. Biomechanical Analysis of Age-Dependent Changes in Fontan Power Loss. Ann Biomed Eng. 2024 Sep; 52(9):2440-2456. View Abstract
  20. The American Association for Thoracic Surgery (AATS) 2024 expert consensus document: Management of neonates and infants with Ebstein anomaly. J Thorac Cardiovasc Surg. 2024 Aug; 168(2):311-324. View Abstract
  21. Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome. Front Cardiovasc Med. 2024; 11:1356010. View Abstract
  22. Impact of Age-Related Change in Caval Flow Ratio on Hepatic Flow Distribution in the Fontan Circulation. Circ Cardiovasc Imaging. 2024 Apr; 17(4):e016104. View Abstract
  23. Erector spinae plane blocks for opioid-sparing multimodal pain management after pediatric cardiac surgery. J Thorac Cardiovasc Surg. 2024 Dec; 168(6):1742-1750.e9. View Abstract
  24. Early and long-term outcomes following cardiac surgery for patients with heterotaxy syndrome. JTCVS Open. 2024 Apr; 18:167-179. View Abstract
  25. Optimal timing of Ross operation in children: A moving target? J Thorac Cardiovasc Surg. 2024 Nov; 168(5):1310-1320.e1. View Abstract
  26. Association of tetralogy of Fallot and complete atrioventricular canal: a single-centre 40-year experience. Eur J Cardiothorac Surg. 2024 Feb 01; 65(2). View Abstract
  27. Mitochondrial transplantation: the advance to therapeutic application and molecular modulation. Front Cardiovasc Med. 2023; 10:1268814. View Abstract
  28. Systemic Atrioventricular Valve Regurgitation in Corrected Transposition of the Great Arteries: Where Are We? J Am Coll Cardiol. 2023 12 05; 82(23):2209-2211. View Abstract
  29. Prognostic utility of a risk prediction model for predischarge major residual lesions or unplanned reinterventions following congenital mitral valve repair. J Thorac Cardiovasc Surg. 2024 Oct; 168(4):1192-1202.e8. View Abstract
  30. Transcatheter Palliation With Pulmonary Artery Flow Restrictors in Neonates With Congenital Heart Disease: Feasibility, Outcomes, and Comparison With a Historical Hybrid Stage 1 Cohort. Circ Cardiovasc Interv. 2023 12; 16(12):e013383. View Abstract
  31. Growth of the Neo-Aortic Root and Prognosis of Transposition of the Great Arteries. J Am Coll Cardiol. 2024 01 30; 83(4):516-527. View Abstract
  32. Model of Ischemia and Reperfusion Injury in Rabbits. J Vis Exp. 2023 Nov 03; (201). View Abstract
  33. Mechanical failure analysis of patch materials used in aortic arch reconstruction: implications for clinical practice. Eur J Cardiothorac Surg. 2023 11 01; 64(5). View Abstract
  34. Postoperative Troponin Levels in Children Undergoing Open Heart Surgery With and Without Coronary Intervention. Pediatr Cardiol. 2024 Jan; 45(1):184-195. View Abstract
  35. Center Volume: The Easy to Measure Imperfect Surrogate. Ann Thorac Surg. 2023 12; 116(6):1240. View Abstract
  36. Right ventricular papillary muscle approximation to the septum as an adjunct technique during tricuspid valve repair in congenital heart surgery. J Thorac Cardiovasc Surg. 2024 May; 167(5):1547-1555.e1. View Abstract
  37. Impact of Age-related change in Caval Flow Ratio on Hepatic Flow Distribution in Fontan. medRxiv. 2023 Sep 08. View Abstract
  38. Comparing apples to apples: Exploring public reporting of congenital cardiac surgery outcomes based on common congenital heart operations. J Thorac Cardiovasc Surg. 2024 May; 167(5):1570-1580.e3. View Abstract
  39. Photopolymerizable Hydrogel for Enhanced Intramyocardial Vascular Progenitor Cell Delivery and Post-Myocardial Infarction Healing. Adv Healthc Mater. 2023 11; 12(29):e2301581. View Abstract
  40. Impact of Residual Lesion Severity on Neurodevelopmental Outcomes Following Congenital Heart Surgery in Infancy and Childhood. Pediatr Cardiol. 2024 Dec; 45(8):1676-1691. View Abstract
  41. A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition. J Vis Exp. 2023 07 21; (197). View Abstract
  42. The Yasui operation: A single institutional experience over 30 years. JTCVS Open. 2023 Sep; 15:361-367. View Abstract
  43. Management of severe calcific aortic stenosis in children with progeria syndrome. J Thorac Cardiovasc Surg. 2023 Nov; 166(5):1292-1297. View Abstract
  44. Mitochondrial transplantation preserves myocardial function and viability in pediatric and neonatal pig hearts donated after circulatory death. J Thorac Cardiovasc Surg. 2024 01; 167(1):e6-e21. View Abstract
  45. Natural history of aortic root dilatation and pathologic aortic regurgitation in tetralogy of Fallot and its morphological variants. J Thorac Cardiovasc Surg. 2023 12; 166(6):1718-1728.e4. View Abstract
  46. Prognostic utility of a novel risk prediction model of 1-year mortality in patients surviving to discharge after surgery for congenital or acquired heart disease. J Thorac Cardiovasc Surg. 2024 02; 167(2):454-463.e6. View Abstract
  47. Natural History of Truncal Root Dilatation and Truncal Valve Regurgitation in Truncus Arteriosus. Ann Thorac Surg. 2023 07; 116(1):78-84. View Abstract
  48. Mitochondrial transplantation: Effects on chemotherapy in prostate and ovarian cancer cells in vitro and in vivo. Biomed Pharmacother. 2023 May; 161:114524. View Abstract
  49. Conduction in congenital heart surgery. J Thorac Cardiovasc Surg. 2023 10; 166(4):1182-1188. View Abstract
  50. Impact of Neighborhood Socioeconomic Status on Outcomes Following First-Stage Palliation of Single Ventricle Heart Disease. J Am Heart Assoc. 2023 03 21; 12(6):e026764. View Abstract
  51. Opportunities of 3-Dimensional Modeling and Quantitative Valve Analysis to Improve Valve Interventions. Circ Cardiovasc Imaging. 2023 03; 16(3):e015267. View Abstract
  52. Transcriptomic and proteomic pathways of diabetic and non-diabetic mitochondrial transplantation. Sci Rep. 2022 12 21; 12(1):22101. View Abstract
  53. Conduction mapping during complex congenital heart surgery: Creating a predictive model of conduction anatomy. J Thorac Cardiovasc Surg. 2023 05; 165(5):1618-1628. View Abstract
  54. Staged ventricular recruitment and biventricular conversion following single-ventricle palliation in unbalanced atrioventricular canal defects. JTCVS Open. 2023 Mar; 13:278-291. View Abstract
  55. Pediatric and Congenital Cardiovascular Disease Research Challenges and Opportunities: JACC Review Topic of the Week. J Am Coll Cardiol. 2022 12 06; 80(23):2239-2250. View Abstract
  56. Case report: Active clinical manifestation of endocardial fibroelastosis in adolescence in a patient with mitral and aortic obstruction-histologic presence of endothelial-to-mesenchymal transformation. Front Cardiovasc Med. 2022; 9:1041039. View Abstract
  57. Symmetric bicuspidizing repair for patients with congenital aortic or truncal valve disease. J Thorac Cardiovasc Surg. 2023 Aug; 166(2):283-291. View Abstract
  58. Ventricular arrhythmias after fibroma resection: Are patients still at risk? Heart Rhythm. 2023 02; 20(2):243-249. View Abstract
  59. Early Experience With Reverse Double Switch Operation for the Borderline Left Heart. Semin Thorac Cardiovasc Surg. 2024 Spring; 36(1):67-79. View Abstract
  60. Contemporary Socioeconomic and Childhood Opportunity Disparities in Congenital Heart Surgery. Circulation. 2022 10 25; 146(17):1284-1296. View Abstract
  61. Intraoperative Residual Lesion Score Predicts Predischarge Major Residual Lesions and Reinterventions Following Congenital Heart Surgery. J Am Coll Cardiol. 2022 09 20; 80(12):1202-1204. View Abstract
  62. Outcomes of Repair of Congenital Aortic Valve Lesions Using Autologous Pericardium vs Porcine Intestinal Submucosa. J Am Coll Cardiol. 2022 09 13; 80(11):1060-1068. View Abstract
  63. A multi-disciplinary, comprehensive approach to management of children with heterotaxy. Orphanet J Rare Dis. 2022 09 09; 17(1):351. View Abstract
  64. Staged Ventricular Septation in Double-Inlet Ventricle - A Strategy to Avoid Fontan? Semin Thorac Cardiovasc Surg. 2024 Spring; 36(1):91-101. View Abstract
  65. Residual Lesion Severity Predicts Midterm Outcomes After Congenital Aortic Valve Repair. Ann Thorac Surg. 2023 01; 115(1):159-165. View Abstract
  66. Tricuspid valve repair concomitant with the Norwood operation among babies with hypoplastic left heart syndrome. Eur J Cardiothorac Surg. 2022 09 02; 62(4). View Abstract
  67. Discussion. J Thorac Cardiovasc Surg. 2023 05; 165(5):e234-e235. View Abstract
  68. Influence of intraoperative residual lesions and timing of extracorporeal membrane oxygenation on outcomes following first-stage palliation of single-ventricle heart disease. J Thorac Cardiovasc Surg. 2023 06; 165(6):2181-2192.e2. View Abstract
  69. Bioprosthetic Aortic Valve Hemodynamics: Definitions, Outcomes, and Evidence Gaps: JACC State-of-the-Art Review. J Am Coll Cardiol. 2022 08 02; 80(5):527-544. View Abstract
  70. A Risk Prediction Model for Reintervention After Total Anomalous Pulmonary Venous Connection Repair. Ann Thorac Surg. 2023 10; 116(4):796-802. View Abstract
  71. Long-Term Outcomes of Patients Requiring Unplanned Repeated Interventions After Surgery for Congenital Heart Disease. J Am Coll Cardiol. 2022 06 28; 79(25):2489-2499. View Abstract
  72. Intraoperative Technical Performance Score Predicts Outcomes After Congenital Cardiac Surgery. Ann Thorac Surg. 2023 02; 115(2):471-477. View Abstract
  73. Timing of reintervention influences survival and resource utilization following first-stage palliation of single ventricle heart disease. J Thorac Cardiovasc Surg. 2023 02; 165(2):436-446. View Abstract
  74. Unrepairable Infant Mitral Valve: An Unexpected Case of Decompensated Heart Failure. Circulation. 2022 04 12; 145(15):1175-1178. View Abstract
  75. Direct Cardiac Compression Devices to Augment Heart Biomechanics and Function. Annu Rev Biomed Eng. 2022 06 06; 24:137-156. View Abstract
  76. Comparison of Intraoperative and Discharge Residual Lesion Severity in Congenital Heart Surgery. Ann Thorac Surg. 2022 11; 114(5):1731-1737. View Abstract
  77. The Right Ventricle and Tricuspid Valve in Fontan Failure: A Role for Early Surgical Management. J Am Coll Cardiol. 2022 05 10; 79(18):1846-1848. View Abstract
  78. Contemporary outcomes of the double switch operation for congenitally corrected transposition of the great arteries. J Thorac Cardiovasc Surg. 2022 12; 164(6):1980-1990.e7. View Abstract
  79. Major Aortopulmonary Collateral Arteries Requiring Percutaneous Intervention Following the Arterial Switch Operation: A Case Series and Systematic Review. World J Pediatr Congenit Heart Surg. 2022 03; 13(2):146-154. View Abstract
  80. Mitochondrial transplantation for organ rescue. Mitochondrion. 2022 05; 64:27-33. View Abstract
  81. Intraoperative conduction mapping in complex congenital heart surgery. JTCVS Tech. 2022 Apr; 12:159-163. View Abstract
  82. Endothelial-to-Mesenchymal Transition as Underlying Mechanism for the Formation of Double-Chambered Right Ventricle. Pediatr Cardiol. 2022 Jun; 43(5):1084-1093. View Abstract
  83. Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment. JACC Basic Transl Sci. 2021 Dec; 6(12):984-999. View Abstract
  84. Mechanical strain triggers endothelial-to-mesenchymal transition of the endocardium in the immature heart. Pediatr Res. 2022 09; 92(3):721-728. View Abstract
  85. Preliminary Results With a Novel Expanded Polytetrafluoroethylene-based Pulmonary Valved Conduit. Ann Thorac Surg. 2022 12; 114(6):2314-2321. View Abstract
  86. Single-Leaflet Aortic Valve Reconstruction Utilizing the Ozaki Technique in Patients With Congenital Aortic Valve Disease. Semin Thorac Cardiovasc Surg. 2022; 34(4):1262-1272. View Abstract
  87. Reply from authors: A new shared vision on survival analysis: Good news from Baltimore. JTCVS Open. 2021 Dec; 8:583-584. View Abstract
  88. Enhancing Recovery in Congenital Cardiac Surgery. Ann Thorac Surg. 2022 11; 114(5):1754-1761. View Abstract
  89. Discussion. J Thorac Cardiovasc Surg. 2023 03; 165(3):113-114. View Abstract
  90. Super Glenn for staged biventricular repair: impact on left ventricular growth? Eur J Cardiothorac Surg. 2021 09 11; 60(3):534-541. View Abstract
  91. Digital solution for follow-up in congenital cardiac surgery. Cardiol Young. 2022 Jul; 32(7):1032-1040. View Abstract
  92. The feasibility of mitral valve device foldoplasty: an in vivo study to evaluate durable retention. Interact Cardiovasc Thorac Surg. 2021 Aug 12. View Abstract
  93. The feasibility of mitral valve device foldoplasty: an in vivo study to evaluate durable retention. Interact Cardiovasc Thorac Surg. 2022 01 06; 34(1):128-136. View Abstract
  94. Importance of Preserved Tricuspid Valve Function for Effective Soft Robotic Augmentation of the Right Ventricle in Cases of Elevated Pulmonary Artery Pressure. Cardiovasc Eng Technol. 2022 02; 13(1):120-128. View Abstract
  95. Management of Congenitally Corrected Transposition of the Great Arteries With Intact Ventricular Septum: Anatomic Repair or Palliative Treatment? Circ Cardiovasc Interv. 2021 07; 14(7):e010154. View Abstract
  96. Aortic Valve Surgery After Neonatal Balloon Aortic Valvuloplasty in Congenital Aortic Stenosis. Circ Cardiovasc Interv. 2021 06; 14(6):e009933. View Abstract
  97. A Tribute to Ajit Yoganathan's Cardiovascular Fluid Mechanics Lab: A Survey of Its Contributions to Our Understanding of the Physiology and Management of Single-Ventricle Patients. Cardiovasc Eng Technol. 2021 12; 12(6):631-639. View Abstract
  98. A Novel Pulmonary Valve Replacement Surgery Strategy Using Contracting Band for Patients With Repaired Tetralogy of Fallot: An MRI-Based Multipatient Modeling Study. Front Bioeng Biotechnol. 2021; 9:638934. View Abstract
  99. Restriction of Atrial Septal Defect Leads to Growth of Hypoplastic Ventricle in Patients with Borderline Right or Left Heart. Semin Thorac Cardiovasc Surg. 2022; 34(1):215-223. View Abstract
  100. The Association of Age and Repair Modification with Outcome after Cone Repair for Ebstein's Malformation. Semin Thorac Cardiovasc Surg. 2022; 34(1):205-212. View Abstract
  101. Biventricular conversion after Fontan completion: A preliminary experience. J Thorac Cardiovasc Surg. 2022 Mar; 163(3):1211-1223. View Abstract
  102. Acute and Short-Term Outcomes of Percutaneous Transcatheter Mitral Valve Replacement in Children. Circ Cardiovasc Interv. 2021 04; 14(4):e009996. View Abstract
  103. Long-term outcomes of truncus arteriosus repair: A modulated renewal competing risks analysis. J Thorac Cardiovasc Surg. 2022 Jan; 163(1):224-236.e6. View Abstract
  104. A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion. J Vis Exp. 2021 02 02; (168). View Abstract
  105. Risk Factors for Left Ventricular Dysfunction Following Surgical Management of Cardiac Fibroma. Circ Cardiovasc Imaging. 2021 02; 14(2):e011748. View Abstract
  106. Human endothelial colony-forming cells provide trophic support for pluripotent stem cell-derived cardiomyocytes via distinctively high expression of neuregulin-1. Angiogenesis. 2021 05; 24(2):327-344. View Abstract
  107. Discussion. J Thorac Cardiovasc Surg. 2021 Mar; 161(3):1165-1166. View Abstract
  108. Commentary: Cone reconstruction for Ebstein's anomaly is here to stay. J Thorac Cardiovasc Surg. 2021 03; 161(3):1110-1111. View Abstract
  109. A Multi-Mode System for Myocardial Functional and Physiological Assessment during Ex Situ Heart Perfusion. J Extra Corpor Technol. 2020 Dec; 52(4):303-313. View Abstract
  110. Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2021 Sep; 162(3):992-1001. View Abstract
  111. Bilateral Erector Spinae Blocks Decrease Perioperative Opioid Use After Pediatric Cardiac Surgery. J Cardiothorac Vasc Anesth. 2021 Jul; 35(7):2082-2087. View Abstract
  112. Technical Performance Score: A Predictor of Outcomes After the Norwood Procedure. Ann Thorac Surg. 2021 10; 112(4):1290-1297. View Abstract
  113. Professor Ajit P. Yoganathan, PhD: "From bench to bedside": Celebrating his contributions to cardiac surgery with an honorary fellowship from the American Association for Thoracic Surgery. J Thorac Cardiovasc Surg. 2021 Mar; 161(3):728-729. View Abstract
  114. Ascending Aortoplasty in Pediatric Patients Undergoing Aortic Valve Procedures. Ann Thorac Surg. 2021 09; 112(3):855-861. View Abstract
  115. Autogenous mitochondria transplantation for treatment of right heart failure. J Thorac Cardiovasc Surg. 2021 07; 162(1):e111-e121. View Abstract
  116. Preoperative Factors That Predict Recurrence After Repair of Discrete Subaortic Stenosis. Ann Thorac Surg. 2021 05; 111(5):1613-1619. View Abstract
  117. Mitochondrial transplantation by intra-arterial injection for acute kidney injury. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F403-F413. View Abstract
  118. Mitochondrial transplantation for myocardial protection in ex-situ?perfused hearts donated after circulatory death. J Heart Lung Transplant. 2020 11; 39(11):1279-1288. View Abstract
  119. Experience and Outcomes of Surgically Implanted Melody Valve in the Pulmonary Position. Ann Thorac Surg. 2021 03; 111(3):966-972. View Abstract
  120. Technical Performance Score's Association With Arterial Switch Operation Outcomes. Ann Thorac Surg. 2021 04; 111(4):1367-1373. View Abstract
  121. 1.5-Ventricle Repair Using Left Ventricle as the Subpulmonary Ventricle. Ann Thorac Surg. 2020 12; 110(6):e529-e530. View Abstract
  122. Modified Ozaki Procedure Including Annular Enlargement for Small Aortic Annuli in Young Patients. Ann Thorac Surg. 2020 10; 110(4):1364-1371. View Abstract
  123. Mitochondrial transplantation for myocardial protection in diabetic hearts. Eur J Cardiothorac Surg. 2020 05 01; 57(5):836-845. View Abstract
  124. Discussion. J Thorac Cardiovasc Surg. 2022 Jan; 163(1):e24-e25. View Abstract
  125. Letter by McCully et al Regarding Article, "Mitochondria Do Not Survive Calcium Overload". Circ Res. 2020 04 10; 126(8):e56-e57. View Abstract
  126. Mitochondrial Transplantation for Myocardial Protection in Ex-Situ Perfused Hearts Donated after Cardio-Circulatory Death. J Heart Lung Transplant. 2020 Apr; 39(4S):S87. View Abstract
  127. Multi-Band Surgery for Repaired Tetralogy of Fallot Patients With Reduced Right Ventricle Ejection Fraction: A Pilot Study. Front Physiol. 2020; 11:198. View Abstract
  128. Minimally Invasive Cardiac Surgical Procedures in Children. Innovations (Phila). 2020 Mar/Apr; 15(2):95-98. View Abstract
  129. Dynamic Augmentation of Left Ventricle and Mitral Valve Function With an Implantable Soft Robotic Device. JACC Basic Transl Sci. 2020 Mar; 5(3):229-242. View Abstract
  130. Reply: Intracoronary Delivery of Mitochondria to Prevent Ischemia-Reperfusion Injury: Challenging Pathway From Bench to Bedside. JACC Basic Transl Sci. 2020 Feb; 5(2):209. View Abstract
  131. A geometrically adaptable heart valve replacement. Sci Transl Med. 2020 02 19; 12(531). View Abstract
  132. Congenital aortic and truncal valve reconstruction using the Ozaki technique: Short-term clinical results. J Thorac Cardiovasc Surg. 2021 05; 161(5):1567-1577. View Abstract
  133. Examination of pathologic features of the right atrioventricular groove in hearts with Ebstein anomaly and correlation with arrhythmias. Heart Rhythm. 2020 07; 17(7):1092-1098. View Abstract
  134. Aortic valve neo-cuspidation using the Ozaki technique for acquired and congenital disease: where does this procedure currently stand? Indian J Thorac Cardiovasc Surg. 2020 Jan; 36(Suppl 1):113-122. View Abstract
  135. Do patients with anomalous origin of the left coronary artery benefit from an early repair of the mitral valve? Eur J Cardiothorac Surg. 2020 01 01; 57(1):72-77. View Abstract
  136. A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy. JACC Basic Transl Sci. 2019 Dec; 4(8):871-888. View Abstract
  137. Fontan with lateral tunnel is associated with improved survival compared with extracardiac conduit. J Thorac Cardiovasc Surg. 2020 04; 159(4):1480-1491.e2. View Abstract
  138. Mitochondrial transplantation enhances murine lung viability and recovery after ischemia-reperfusion injury. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L78-L88. View Abstract
  139. [Current surgical options and outcomes for newborns with hypoplastic left heart syndrome]. An Pediatr (Engl Ed). 2019 Nov; 91(5):352.e1-352.e9. View Abstract
  140. Initial experience introducing an enhanced recovery program in congenital cardiac surgery. J Thorac Cardiovasc Surg. 2020 11; 160(5):1313-1321.e5. View Abstract
  141. Corrigendum to "Patient-specific in vivo right ventricle material parameter estimation for patients with tetralogy of fallot using MRI-Based models with different zero-load diastole and systole morphologies" [Int. J. Cardiol. 276 (2019) 93-99]. Int J Cardiol. 2020 Mar 15; 303:87. View Abstract
  142. Flow disturbances and the development of endocardial fibroelastosis. J Thorac Cardiovasc Surg. 2020 Feb; 159(2):637-646. View Abstract
  143. Repair of double outlet right ventricle: Midterm outcomes. J Thorac Cardiovasc Surg. 2020 Jan; 159(1):254-264. View Abstract
  144. Preischemic autologous mitochondrial transplantation by intracoronary injection for myocardial protection. J Thorac Cardiovasc Surg. 2020 Aug; 160(2):e15-e29. View Abstract
  145. Ventricle stress/strain comparisons between Tetralogy of Fallot patients and healthy using models with different zero-load diastole and systole morphologies. PLoS One. 2019; 14(8):e0220328. View Abstract
  146. Delayed Transplantation of Autologous Mitochondria for Cardioprotection in a Porcine Model. Ann Thorac Surg. 2020 03; 109(3):711-719. View Abstract
  147. Mitochondrial transplantation ameliorates acute limb ischemia. J Vasc Surg. 2020 03; 71(3):1014-1026. View Abstract
  148. Long-term Surgical Prognosis of Primary Supravalvular Aortic Stenosis Repair. Ann Thorac Surg. 2019 10; 108(4):1202-1209. View Abstract
  149. Flow disturbances and progression of endocardial fibroelastosis - a case report. Cardiovasc Pathol. 2019 Sep - Oct; 42:1-3. View Abstract
  150. Interdigitating Myocardial Tongues in Pediatric Cardiac Fibromas: Plausible Substrate for Ventricular Tachycardia and Cardiac Arrest. JACC Clin Electrophysiol. 2019 05; 5(5):563-575. View Abstract
  151. Mechanical Properties of Autologous Pericardium Change With Fixation Time: Implications for Valve Reconstruction. Semin Thorac Cardiovasc Surg. 2019; 31(4):852-854. View Abstract
  152. Temporal enhancement of 2D color Doppler echocardiography sequences by fragment-based frame reordering and refinement. Int J Comput Assist Radiol Surg. 2019 Apr; 14(4):577-586. View Abstract
  153. An intraoperative test device for aortic valve repair. J Thorac Cardiovasc Surg. 2019 01; 157(1):126-132. View Abstract
  154. Mitochondrial transplantation prolongs cold ischemia time in murine heart transplantation. J Heart Lung Transplant. 2019 01; 38(1):92-99. View Abstract
  155. Outcomes after mechanical aortic valve replacement in children and young adults with congenital heart disease. J Thorac Cardiovasc Surg. 2019 01; 157(1):329-340. View Abstract
  156. Patient-specific in vivo right ventricle material parameter estimation for patients with tetralogy of Fallot using MRI-based models with different zero-load diastole and systole morphologies. Int J Cardiol. 2019 Feb 01; 276:93-99. View Abstract
  157. Impact of surgical pulmonary valve replacement on ventricular strain and synchrony in patients with repaired tetralogy of Fallot: a cardiovascular magnetic resonance feature tracking study. J Cardiovasc Magn Reson. 2018 06 18; 20(1):37. View Abstract
  158. Reply to Buratto et al. Eur J Cardiothorac Surg. 2018 06 01; 53(6):1296. View Abstract
  159. Predictors of Postoperative Rehabilitation Therapy Following Congenital Heart Surgery. J Am Heart Assoc. 2018 05 12; 7(10). View Abstract
  160. Dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: Case report and failure analysis. J Thorac Cardiovasc Surg. 2018 10; 156(4):e165-e168. View Abstract
  161. A leaflet plication clip is an effective surgical template for mitral valve foldoplasty. Eur J Cardiothorac Surg. 2018 05 01; 53(5):939-944. View Abstract
  162. Staged ventricular recruitment in patients with borderline ventricles and large ventricular septal defects. J Thorac Cardiovasc Surg. 2018 07; 156(1):254-264. View Abstract
  163. Cell-Based Therapy With Cardiosphere-Derived Cardiocytes: A New Hope for Pediatric Patients With Single Ventricle Congenital Heart Disease? Circ Res. 2018 03 30; 122(7):916-917. View Abstract
  164. Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria. Mitochondrion. 2019 05; 46:103-115. View Abstract
  165. A novel wall water system for cardiopulmonary bypass may reduce the risk of aerosolized infection. J Thorac Cardiovasc Surg. 2018 07; 156(1):318-324. View Abstract
  166. Targeted Increase in Pulmonary Blood Flow in a Bidirectional Glenn Circulation. Semin Thorac Cardiovasc Surg. 2018; 30(2):182-188. View Abstract
  167. Fast image-based mitral valve simulation from individualized geometry. Int J Med Robot. 2018 Apr; 14(2). View Abstract
  168. Technical Performance Score Predicts Partial/Transitional Atrioventricular Septal Defect Outcomes. Ann Thorac Surg. 2018 05; 105(5):1461-1468. View Abstract
  169. Transit and integration of extracellular mitochondria in human heart cells. Sci Rep. 2017 12 12; 7(1):17450. View Abstract
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  520. Bidirectional superior cavopulmonary anastomosis improves mechanical efficiency in dilated atriopulmonary connections. J Thorac Cardiovasc Surg. 1999 Oct; 118(4):681-91. View Abstract
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  522. Increased myocardial calcium cycling and reduced myofilament calcium sensitivity in early endotoxemia. Surgery. 1999 Aug; 126(2):231-8. View Abstract
  523. Valved homograft conduit repair of the right heart in early infancy. Ann Thorac Surg. 1999 Aug; 68(2):542-8. View Abstract
  524. Superior myocardial protection with a new histidine-buffered crystalloid cardioplegic solution in clinical trial. Thorac Cardiovasc Surg. 1999 Jun; 47(3):148-52. View Abstract
  525. Editorial: Partial left ventriculectomy for dilated cardiomyopathy in children. J Thorac Cardiovasc Surg. 1999 May; 117(5):918-9. View Abstract
  526. Fluid dynamic comparison of intra-atrial and extracardiac total cavopulmonary connections. J Thorac Cardiovasc Surg. 1999 Apr; 117(4):697-704. View Abstract
  527. Mechanical circulatory support in children with cardiac disease. J Thorac Cardiovasc Surg. 1999 Mar; 117(3):529-42. View Abstract
  528. Vesnarinone and amrinone reduce the systemic inflammatory response syndrome. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):375-82. View Abstract
  529. Left ventricular assist device improves survival in children with left ventricular dysfunction after repair of anomalous origin of the left coronary artery from the pulmonary artery. Ann Thorac Surg. 1999 Jan; 67(1):169-72. View Abstract
  530. Glucose transporter upregulation improves ischemic tolerance in hypertrophied failing heart. Circulation. 1998 Nov 10; 98(19 Suppl):II234-9; discussion II240-1. View Abstract
  531. Diastolic dysfunction coincides with early mild transplant rejection: in situ measurements in a heterotopic rat heart transplant model. J Heart Lung Transplant. 1998 Nov; 17(11):1049-56. View Abstract
  532. Idiopathic dilated cardiomyopathy: a superantigen-driven autoimmune disease. Circulation. 1998 Aug 25; 98(8):777-85. View Abstract
  533. Use of rapid-deployment extracorporeal membrane oxygenation for the resuscitation of pediatric patients with heart disease after cardiac arrest. J Thorac Cardiovasc Surg. 1998 Aug; 116(2):305-11. View Abstract
  534. Administration of fructose 1,6-diphosphate during early reperfusion significantly improves recovery of contractile function in the postischemic heart. J Thorac Cardiovasc Surg. 1998 Aug; 116(2):335-43. View Abstract
  535. Fluorescence measurement of calcium transients in perfused rabbit heart using rhod 2. Am J Physiol. 1998 02; 274(2):H728-41. View Abstract
  536. Minimal-access surgery for congenital heart defects. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 1998; 1:75-80. View Abstract
  537. Left ventricular dysfunction after open repair of simple congenital heart defects in infants and children. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):74-6. View Abstract
  538. Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg. 1997 Dec; 114(6):991-1000; discussion 1000-1. View Abstract
  539. Adenosine prevents protein kinase C activation during hypothermic ischemia. Circulation. 1997 Nov 04; 96(9 Suppl):II-221-5; discussion II-225-6. View Abstract
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  541. Myocardial protection and cardiopulmonary bypass in neonates and infants. Ann Thorac Surg. 1997 Sep; 64(3):878-9. View Abstract
  542. Potential role of mechanical stress in the etiology of pediatric heart disease: septal shear stress in subaortic stenosis. J Am Coll Cardiol. 1997 Jul; 30(1):247-54. View Abstract
  543. Hemodynamic effect of progressive right atrial dilatation in atriopulmonary connections. J Thorac Cardiovasc Surg. 1997 Jul; 114(1):2-8. View Abstract
  544. [Inappropriate preservation of myocardium by topical cooling with iced slush]. Nihon Kyobu Geka Gakkai Zasshi. 1996 Sep; 44(9):1691-7. View Abstract
  545. [Cardiac disfunction and myocardial energy metabolism caused by interleukin-2 (IL-2)]. Kyobu Geka. 1996 Apr; 49(4):278-80. View Abstract
  546. Extracorporeal membrane oxygenation for cardiac support in children. Ann Thorac Surg. 1996 Jan; 61(1):336-9; discussion 340-1. View Abstract
  547. [Prolonged preservation due to acceleration of anaerobic glycolysis with histidine buffered cardioplegia in canine heart]. Nihon Kyobu Geka Gakkai Zasshi. 1995 Dec; 43(12):1895-901. View Abstract
  548. Protein kinase C activation in the heart: effects on calcium and contractile proteins. Ann Thorac Surg. 1995 Dec; 60(6 Suppl):S505-8. View Abstract
  549. Improved protection of the hypertrophied left ventricle by histidine-containing cardioplegia. Circulation. 1995 Nov 01; 92(9 Suppl):II395-9. View Abstract
  550. Characterization of inducible nitric oxide synthase expression in endotoxemic rat cardiac myocytes in vivo and following cytokine exposure in vitro. J Mol Cell Cardiol. 1995 Sep; 27(9):2015-29. View Abstract
  551. [Fructose 1,6-diphosphate can be a substrate to accelerate glycolysis]. Nihon Kyobu Geka Gakkai Zasshi. 1995 Aug; 43(8):1126-31. View Abstract
  552. Direct detrimental effects of L-arginine upon ischemia--reperfusion injury to myocardium. J Mol Cell Cardiol. 1995 Jul; 27(7):1405-14. View Abstract
  553. [Improved protection of hypertrophied myocardium in ischemia by histidine buffer cardioplegia]. Kyobu Geka. 1995 Jun; 48(6):461-3. View Abstract
  554. Coronary vasoconstriction mediated by endothelin-1 in neonates. Reversal by nitroglycerin. J Thorac Cardiovasc Surg. 1995 Jan; 109(1):88-97; discussion 97-8. View Abstract
  555. Endothelium-dependent regulation of coronary tone in the neonatal pig. Anesth Analg. 1994 Dec; 79(6):1094-101. View Abstract
  556. Orthotopic heart transplantation in children with congenital heart disease. Ann Thorac Surg. 1994 Dec; 58(6):1664-9. View Abstract
  557. Extracorporeal membrane oxygenation support as a bridge to pediatric heart transplantation. Circulation. 1994 Nov; 90(5 Pt 2):II66-9. View Abstract
  558. Evaluation of highly buffered low-calcium solution for long-term preservation of the heart. Comparison with University of Wisconsin solution. J Thorac Cardiovasc Surg. 1994 Oct; 108(4):762-71. View Abstract
  559. Prolonged neonatal myocardial preservation with a highly buffered low-calcium solution. J Thorac Cardiovasc Surg. 1994 Oct; 108(4):772-9. View Abstract
  560. Transatrial lead placement for endocardial pacing in children. Ann Thorac Surg. 1994 Jul; 58(1):97-101; discussion 101-2. View Abstract
  561. Left main bronchus compression after arterial switch for transposition. Ann Thorac Surg. 1994 May; 57(5):1320-2. View Abstract
  562. Myocardial effects of interleukin-2. Transplant Proc. 1994 Feb; 26(1):209-10. View Abstract
  563. Cardiopulmonary bypass significantly reduces surfactant activity in children. J Thorac Cardiovasc Surg. 1993 Dec; 106(6):968-77. View Abstract
  564. [Buffering capacity of histidine in cardioplegia analyzed by myocardial production of lactate and alanine]. Kyobu Geka. 1993 Nov; 46(12):1021-4. View Abstract
  565. Improved survival following pediatric cardiac transplantation in high-risk patients. Circulation. 1993 Nov; 88(5 Pt 2):II218-23. View Abstract
  566. Extracorporeal membrane oxygenation for cardiac rescue in children with severe myocardial dysfunction. Crit Care Med. 1993 Jul; 21(7):1020-8. View Abstract
  567. Redistribution of myocardial calcium during ischemia. Relationship to onset of contracture. J Thorac Cardiovasc Surg. 1993 Jun; 105(6):988-94. View Abstract
  568. Pharmacokinetics of intravenous vancomycin in pediatric cardiopulmonary bypass surgery. Pediatr Infect Dis J. 1993 Apr; 12(4):300-4. View Abstract
  569. A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression. J Thorac Cardiovasc Surg. 1993 Mar; 105(3):464-72; discussion 472-3. View Abstract
  570. Successful treatment of acute myocarditis using extracorporeal membrane oxygenation. Crit Care Med. 1993 Feb; 21(2):302-4. View Abstract
  571. Morphology of ventricular septal defects in complete transposition. Surgical implications. J Thorac Cardiovasc Surg. 1992 Nov; 104(5):1203-11. View Abstract
  572. Extracorporeal membrane oxygenator rescue in children during cardiac arrest after cardiac surgery. Circulation. 1992 Nov; 86(5 Suppl):II300-4. View Abstract
  573. The role of magnesium in postischemic cardiac dysfunction. Surgery. 1992 Aug; 112(2):159-65. View Abstract
  574. Age-related differences in cardiac susceptibility to ischemia/reperfusion injury. Response to deferoxamine. J Thorac Cardiovasc Surg. 1992 Jul; 104(1):165-72. View Abstract
  575. Toxoplasmosis in pediatric recipients of heart transplants. Clin Infect Dis. 1992 Apr; 14(4):847-51. View Abstract
  576. The clinical trial of FK 506 as primary and rescue immunosuppression in pediatric cardiac transplantation. Transplant Proc. 1991 Dec; 23(6):3058-60. View Abstract
  577. Coarctation and hypoplasia of the aortic arch: will the arch grow? Ann Thorac Surg. 1991 Sep; 52(3):608-13; discussion 613-4. View Abstract
  578. Improvement in oxygen tensions and pulmonary blood flow with intermittent distal aortic compression during normoxia, hypoxic hypoxia, and hyperoxia in neonatal piglets. Crit Care Med. 1991 May; 19(5):736-41. View Abstract
  579. The surgical anatomy of tetralogy of Fallot with pulmonary atresia rather than pulmonary stenosis. J Card Surg. 1991 Mar; 6(1):41-58; discussion 58-9. View Abstract
  580. Cardiac transplantation at the University of Pittsburgh: 1980 to 1991. Clin Transpl. 1991; 87-95. View Abstract
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  582. Effects of low extracellular calcium on cytosolic calcium and ischemic contracture. J Surg Res. 1990 Sep; 49(3):252-5. View Abstract
  583. The effect of cardiac hypertrophy on changes in cytosolic free calcium concentration during ischemia. Surgery. 1990 Aug; 108(2):312-6; discussion 316-7. View Abstract
  584. Carotid artery approach for balloon dilation of aortic valve stenosis in the neonate: a preliminary report. J Am Coll Cardiol. 1990 Jun; 15(7):1633-6. View Abstract
  585. Calcium paradox in an in vivo model of multidose cardioplegia and moderate hypothermia. Prevention with diltiazem or trace calcium levels. J Thorac Cardiovasc Surg. 1990 Mar; 99(3):475-83. View Abstract
  586. Surgical correction of pulmonary atresia with ventricular septal defect and no central pulmonary arteries. Am J Cardiol. 1990 Jan 15; 65(3):261-3. View Abstract
  587. Amelioration of postischemic stunning by deferoxamine-blood cardioplegia. Circulation. 1989 Nov; 80(5 Pt 2):III30-5. View Abstract
  588. Maturational difference in functional/metabolic sequelae of free radical formation on reperfusion. J Surg Res. 1989 Jun; 46(6):532-6. View Abstract
  589. Temporary epicardial pacing after open heart surgery: complications and prevention. J Card Surg. 1989 Mar; 4(1):99-103. View Abstract
  590. Successful use of intraaortic balloon pumping in a 2-kilogram infant. Ann Thorac Surg. 1988 Nov; 46(5):574-6. View Abstract
  591. Closed heart surgery for congenital heart disease in infancy. Clin Perinatol. 1988 Sep; 15(3):681-97. View Abstract
  592. Inadequate myocardial protection with cold cardioplegic arrest during repair of tetralogy of Fallot. J Thorac Cardiovasc Surg. 1988 Feb; 95(2):223-9. View Abstract
  593. Impaired left ventricular postischemic function and metabolism in chronic right ventricular hypertrophy. Circulation. 1987 Nov; 76(5 Pt 2):V168-73. View Abstract
  594. Evidence of myocardial free radical injury during elective repair of tetralogy of Fallot. Circulation. 1987 Nov; 76(5 Pt 2):V174-9. View Abstract
  595. Changes in pericardial surface pressure during pulmonary hypertensive crises after cardiac surgery. Circulation. 1987 Sep; 76(3 Pt 2):III93-6. View Abstract
  596. Mitral valve replacement in dogs. Surgical technique and postoperative management. Vet Surg. 1987 May-Jun; 16(3):231-7. View Abstract
  597. Technique and postoperative management for successful cardiopulmonary bypass and open-heart surgery in dogs. J Am Vet Med Assoc. 1987 Apr 01; 190(7):869-74. View Abstract
  598. Synthetic patch angioplasty for repair of coarctation of the aorta: experience with aneurysm formation. Circulation. 1986 Sep; 74(3 Pt 2):I32-6. View Abstract
  599. Exogenous substrate preference of the post-ischaemic myocardium. Cardiovasc Res. 1986 Apr; 20(4):256-63. View Abstract
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