Research Overview

Dr. Grant is the Director of the Fetal-Neonatal Neuroimaging and Developmental Science Center (FNNDSC) at Children's Hospital Boston. The center's purpose is to create the infrastructure and provide the expertise needed to support and foster cutting edge clinical and translational science research involving magnetic resonance imaging (MRI), magnetoencephalography (MEG) and near-infrared spectroscopy (NIRS) across multiple subspecialties. The center's work addresses critical needs in the pediatric population: Children are different than adults: Children's brains go through dramatic changes in size and composition, with associated physiological changes. Children need technology developed for the unique size and physiology of their brains. Children's brains are not fully "online": It is impossible, for example, to test an infant's language function, so it is important to develop imaging approaches that permit clinicians to evaluate the structures and the physiological health of regions that will promote developing functions. This will allow clinicians to better predict function in individual children. Children's brains are much more plastic than adult brains: To optimize the potential of each individual child, safe methods are needed to monitor brain growth and development as well as response to therapy. The multiple modalities employed by the center are safe and provide the most sophisticated means of monitoring brain heath. The development of a child's brain is an extremely complex process: A multidisciplinary center, where clinicians and scientists can come together and work with a common set of tools, is necessary to improve knowledge of brain development.

Research Background

Dr. Grant holds a Master of Science degree in physics and an MD from the University of Toronto. She did her radiology residency at Vancouver General Hospital in British Columbia, Canada, and her fellowship in adult and pediatric neuroradiology at the University of California, San Francisco. She is now a Professor of Radiology and Pediatrics at the Harvard Medical School. Dr. Grant headed the Division of Pediatric Radiology at Massachusetts General Hospital for five years before moving to Children's Hospital Boston to become the founding director of the Fetal-Neonatal Neuroimaging and Developmental Science Center and the first incumbent of Children's Hospital Boston Chair in Neonatology. At Children's she holds appointments in the Division of Newborn Medicine and the Department of Radiology. Dr. Grant is a co-author of two popular textbooks for clinical neuroradiology and has won a number of awards for her research efforts as well as recognition for her clinical excellence.

 

Education

Undergraduate School

BSc, Physics University of Toronto
1984 Toronto, Ontario Canada

Graduate School

MSc, Theoretical Physics University of Toronto
1988 Toronto, Ontario Canada

Medical School

University of Toronto
1989 Toronto, Ontario Canada

Internship

St. Paul's Hospital
1990 Vancouver, British Columbia Canada

Residency

Radiology Vancouver General Hospital
1994 Vancouver, British Columbia Canada

Fellowship

Neuroradiology; Pediatric Neuroradiology University of California, San Francisco
1996 San Francisco CA

Publications

  1. Machine learning to infer neurocognitive testing scores among adolescents and young adults with congenital heart disease. Commun Med (Lond). 2026 Feb 06; 6(1). View Abstract
  2. Insights into Temporal and Spatial Dynamics of Short Association Fiber Formation in the Human Fetal Brain. bioRxiv. 2025 Oct 21. View Abstract
  3. Typical development of the human fetal subplate: regional heterogeneity, growth, and asymmetry assessed by in vivo T2-weighted MRI. bioRxiv. 2025 Oct 07. View Abstract
  4. Magnetic resonance imaging and spectroscopy in neonatal encephalopathy: current consensus position and future opportunities. Pediatr Res. 2025 Oct 03. View Abstract
  5. Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia. bioRxiv. 2025 Sep 29. View Abstract
  6. Maternal Childhood Neglect is Linked to Greater Infant Cortisol Levels and Larger Infant Limbic Volumes. Child Maltreat. 2025 Sep 15; 10775595251376623. View Abstract
  7. Conditional deep generative normative modeling for structural and developmental anomaly detection in the fetal brain. Neuroimage. 2025 Oct 01; 319:121442. View Abstract
  8. The Role of Scalp EEG Recordings During Cortical Visual Prosthesis Testing. Artif Organs. 2025 Sep; 49(9):1417-1428. View Abstract
  9. Design and rationale of "Antecedents and correlates of well-being in young adults with congenital heart disease in the Boston Circulatory Arrest Study (BCAS-adult)". Am Heart J. 2025 Nov; 289:127-137. View Abstract
  10. Fetal MRI: Radiofrequency Safety Assessment at 3 Tesla. J Magn Reson Imaging. 2025 Sep; 62(3):844-853. View Abstract
  11. Bahir Dar Child Development Cross-Sectional Study, Ethiopia: study protocol. BMJ Paediatr Open. 2025 Apr 02; 9(1). View Abstract
  12. Towards automatic US-MR fetal brain image registration with learning-based methods. Neuroimage. 2025 Apr 15; 310:121104. View Abstract
  13. Graph-based prototype inverse-projection for identifying cortical sulcal pattern abnormalities in congenital heart disease. Med Image Anal. 2025 May; 102:103538. View Abstract
  14. Magnetic resonance imaging findings in SCN1A-related epilepsies and Dravet syndrome: A systematic review. Epilepsia. 2025 Jun; 66(6):1793-1803. View Abstract
  15. Management and Outcomes in Isolated Congenital Aqueductal Stenosis: A Single-Center Retrospective Cohort Study. Prenat Diagn. 2025 04; 45(4):521-530. View Abstract
  16. Impact of maternal antenatal nutrition and infection treatment interventions on Longitudinal Infant Development and Growth in rural Ethiopia: protocol of the LIDG child follow-up study. BMJ Paediatr Open. 2024 12 24; 8(1). View Abstract
  17. Symptoms Do Not Predict White Matter Injury in the Watershed Regions in Children with Moyamoya. J Pediatr. 2025 Jan; 276:114372. View Abstract
  18. Proceedings of the 15th International Newborn Brain Conference: Neuro-imaging studies: Fota Island, Cork, Ireland, February 28th - March 2nd 2024. J Neonatal Perinatal Med. 2024 Aug 05; 17(3):S421-S445. View Abstract
  19. Whole-body hypothermia in mild neonatal encephalopathy: protocol for a multicentre phase III randomised controlled trial. BMC Pediatr. 2024 Jul 18; 24(1):460. View Abstract
  20. Network conditioning for synergistic learning on partial annotations. Proc Mach Learn Res. 2024 Jul; 250:119-130. View Abstract
  21. Magnetoencephalography for the pediatric population, indications, acquisition and interpretation for the clinician. Neuroradiol J. 2025 Feb; 38(1):7-20. View Abstract
  22. Meta-regression of sulcal patterns, clinical and environmental factors on neurodevelopmental outcomes in participants with multiple CHD types. Cereb Cortex. 2024 06 04; 34(6). View Abstract
  23. Automatic cortical surface parcellation in the fetal brain using attention-gated spherical U-net. Front Neurosci. 2024; 18:1410936. View Abstract
  24. Publisher Correction to: Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex. J Autism Dev Disord. 2024 Mar; 54(3):1232. View Abstract
  25. A Prospective Multi-Institutional Study Comparing the Brain Development in the Third Trimester between Opioid-Exposed and Nonexposed Fetuses Using Advanced Fetal MR Imaging Techniques. AJNR Am J Neuroradiol. 2024 02 07; 45(2):218-223. View Abstract
  26. Divergent growth of the transient brain compartments in fetuses with nonsyndromic isolated clefts involving the primary and secondary palate. Cereb Cortex. 2024 01 31; 34(2). View Abstract
  27. Zero-DeepSub: Zero-shot deep subspace reconstruction for rapid multiparametric quantitative MRI using 3D-QALAS. Magn Reson Med. 2024 Jun; 91(6):2459-2482. View Abstract
  28. Association between placental oxygen transport and fetal brain cortical development: a study in monochorionic diamniotic twins. Cereb Cortex. 2024 01 14; 34(1). View Abstract
  29. Deep Learning-Based Visual Complexity Analysis of Electroencephalography Time-Frequency Images: Can It Localize the Epileptogenic Zone in the Brain? Algorithms. 2023 Dec; 16(12). View Abstract
  30. Shape-aware Segmentation of the Placenta in BOLD Fetal MRI Time Series. J Mach Learn Biomed Imaging. 2023 Dec; 2(PIPPI 2022):527-546. View Abstract
  31. Association of genetic and sulcal traits with executive function in congenital heart disease. Ann Clin Transl Neurol. 2024 02; 11(2):278-290. View Abstract
  32. Local SAR management strategies to use two-channel RF shimming for fetal MRI at 3?T. Magn Reson Med. 2024 Mar; 91(3):1165-1178. View Abstract
  33. Atypical fetal brain development in fetuses with non-syndromic isolated musculoskeletal birth defects (niMSBDs). Cereb Cortex. 2023 10 14; 33(21):10793-10801. View Abstract
  34. Sleep Spindle Generation Before and After Epilepsy Surgery: A Source Imaging Study in Children with Drug-Resistant Epilepsy. Brain Topogr. 2024 01; 37(1):88-101. View Abstract
  35. Time-efficient, high-resolution 3T whole-brain relaxometry using 3D-QALAS with wave-CAIPI readouts. Magn Reson Med. 2024 Feb; 91(2):630-639. View Abstract
  36. Analgesia after dorsal root ganglionic injection under CT-guidance in a patient with intractable phantom limb pain. Pain Med. 2023 09 01; 24(9):1122-1123. View Abstract
  37. Acute Diffusion-Weighted Imaging Signaling Severe Periventricular Leukomalacia in Preterm Infants: Case Report and Review of Literature. J Child Neurol. 2023 08; 38(8-9):489-497. View Abstract
  38. Negative versus withdrawn maternal behavior: Differential associations with infant gray and white matter during the first 2?years of life. Hum Brain Mapp. 2023 08 15; 44(12):4572-4589. View Abstract
  39. SSL-QALAS: Self-Supervised Learning for rapid multiparameter estimation in quantitative MRI using 3D-QALAS. Magn Reson Med. 2023 11; 90(5):2019-2032. View Abstract
  40. Association of cerebral metabolic rate following therapeutic hypothermia with 18-month neurodevelopmental outcomes after neonatal hypoxic ischemic encephalopathy. EBioMedicine. 2023 Aug; 94:104673. View Abstract
  41. NeSVoR: Implicit Neural Representation for Slice-to-Volume Reconstruction in MRI. IEEE Trans Med Imaging. 2023 06; 42(6):1707-1719. View Abstract
  42. Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex. J Autism Dev Disord. 2024 Aug; 54(8):3155-3175. View Abstract
  43. Single Ventricle Reconstruction III: Brain Connectome and Neurodevelopmental Outcomes: Design, Recruitment, and Technical Challenges of a Multicenter, Observational Neuroimaging Study. Diagnostics (Basel). 2023 Apr 30; 13(9). View Abstract
  44. Single Ventricle Reconstruction III: Brain Connectome and Neurodevelopmental Outcomes: Design, Recruitment, and Technical Challenges of a Multicenter, Observational Neuroimaging Study. medRxiv. 2023 Apr 17. View Abstract
  45. Abnormal prenatal brain development in Chiari II malformation. Front Neuroanat. 2023; 17:1116948. View Abstract
  46. Aluminum Thin Film Nanostructure Traces in Pediatric EEG Net for MRI and CT Artifact Reduction. Sensors (Basel). 2023 Mar 31; 23(7). View Abstract
  47. Diffusion-Weighted Magnetic Resonance Imaging Demonstrates White Matter Alterations in Watershed Regions in Children With Moyamoya Without Stroke or Silent Infarct. Pediatr Neurol. 2023 06; 143:89-94. View Abstract
  48. Abnormal development of transient fetal zones in mild isolated fetal ventriculomegaly. Cereb Cortex. 2023 02 07; 33(4):1130-1139. View Abstract
  49. Editorial: Imaging the developing connectome of perinatal brain. Front Neurosci. 2023; 17:1122829. View Abstract
  50. Effect of neonatal seizure burden and etiology on the long-term outcome: data from a randomized, controlled trial. Ann Child Neurol Soc. 2023 Mar; 1(1):53-65. View Abstract
  51. A high-resolution pediatric female whole-body numerical model with comparison to a male model. Phys Med Biol. 2023 01 13; 68(2). View Abstract
  52. Cross-Sectional Observational Study of Typical in utero Fetal Movements Using Machine Learning. Dev Neurosci. 2023; 45(3):105-114. View Abstract
  53. Patterns of Neural Functional Connectivity in Infants at Familial Risk of Developmental Dyslexia. JAMA Netw Open. 2022 10 03; 5(10):e2236102. View Abstract
  54. MRI Findings in Third-Trimester Opioid-Exposed Fetuses, With Focus on Brain Measurements: A Prospective Multicenter Case-Control Study. AJR Am J Roentgenol. 2023 03; 220(3):418-427. View Abstract
  55. SVoRT: Iterative Transformer for Slice-to-Volume Registration in Fetal Brain MRI. Med Image Comput Comput Assist Interv. 2022 Sep; 13436:3-13. View Abstract
  56. Quantification of sulcal emergence timing and its variability in early fetal life: Hemispheric asymmetry and sex difference. Neuroimage. 2022 11; 263:119629. View Abstract
  57. Parallel transmission 2D RARE imaging at 7T with transmit field inhomogeneity mitigation and local SAR control. Magn Reson Imaging. 2022 11; 93:87-96. View Abstract
  58. A Role for Data Science in Precision Nutrition and Early Brain Development. Front Psychiatry. 2022; 13:892259. View Abstract
  59. Increased Breastfeeding Proportion Is Associated with Improved Gross Motor Skills at 3-5 Years of Age: A Pilot Study. Nutrients. 2022 May 26; 14(11). View Abstract
  60. Age-related topographic map of magnetic resonance diffusion metrics in neonatal brains. Hum Brain Mapp. 2022 10 01; 43(14):4326-4334. View Abstract
  61. Deep learning of birth-related infant clavicle fractures: a potential virtual consultant for fracture dating. Pediatr Radiol. 2022 10; 52(11):2206-2214. View Abstract
  62. Clinical experience with an in-NICU magnetic resonance imaging system. J Perinatol. 2022 07; 42(7):873-879. View Abstract
  63. Magnetic resonance imaging metrics of oxygen extraction fraction: Contradictions or insight into pathophysiological mechanisms? Am J Hematol. 2022 06 01; 97(6):679-681. View Abstract
  64. Volumetric Parameterization of the Placenta to a Flattened Template. IEEE Trans Med Imaging. 2022 04; 41(4):925-936. View Abstract
  65. Fetal Brain Volume Predicts Neurodevelopment in Congenital Heart Disease. Circulation. 2022 04 12; 145(15):1108-1119. View Abstract
  66. Improving Infant Hydrocephalus Outcomes in Uganda: A Longitudinal Prospective Study Protocol for Predicting Developmental Outcomes and Identifying Patients at Risk for Early Treatment Failure after ETV/CPC. Metabolites. 2022 Jan 14; 12(1). View Abstract
  67. Proceedings of the 13th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical. J Neonatal Perinatal Med. 2022; 15(2):453-465. View Abstract
  68. Assessment of Maternal Macular Pigment Optical Density (MPOD) as a Potential Marker for Dietary Carotenoid Intake during Lactation in Humans. Nutrients. 2021 Dec 31; 14(1). View Abstract
  69. Automated detection and reacquisition of motion-degraded images in fetal HASTE imaging at 3 T. Magn Reson Med. 2022 04; 87(4):1914-1922. View Abstract
  70. Fetal Neuroimaging Updates. Magn Reson Imaging Clin N Am. 2021 Nov; 29(4):557-581. View Abstract
  71. Edited magnetic resonance spectroscopy in the neonatal brain. Neuroradiology. 2022 Feb; 64(2):217-232. View Abstract
  72. Optimal Method for Fetal Brain Age Prediction Using Multiplanar Slices From Structural Magnetic Resonance Imaging. Front Neurosci. 2021; 15:714252. View Abstract
  73. Maternal Childhood Maltreatment Is Associated With Lower Infant Gray Matter Volume and Amygdala Volume During the First Two Years of Life. Biol Psychiatry Glob Open Sci. 2022 Oct; 2(4):440-449. View Abstract
  74. STRESS: Super-Resolution for Dynamic Fetal MRI using Self-Supervised Learning. Med Image Comput Comput Assist Interv. 2021 Sep-Oct; 12907:197-206. View Abstract
  75. Comparison of prospective and retrospective motion correction in 3D-encoded neuroanatomical MRI. Magn Reson Med. 2022 02; 87(2):629-645. View Abstract
  76. Abnormal Right-Hemispheric Sulcal Patterns Correlate with Executive Function in Adolescents with Tetralogy of Fallot. Cereb Cortex. 2021 08 26; 31(10):4670-4680. View Abstract
  77. Quantitative T1 and T2 mapping by magnetic resonance fingerprinting (MRF) of the placenta before and after maternal hyperoxia. Placenta. 2021 10; 114:124-132. View Abstract
  78. Numerical simulation of the radiofrequency safety of 128-channel hd-EEG nets on a 29-month-old whole-body model in a 3 Tesla MRI. IEEE Trans Electromagn Compat. 2021 Oct; 63(5):1748-1756. View Abstract
  79. Functional Connectivity in Infancy and Toddlerhood Predicts Long-Term Language and Preliteracy Outcomes. Cereb Cortex. 2021 08 04; 32(4). View Abstract
  80. Safety and imaging performance of two-channel RF shimming for fetal MRI at 3T. Magn Reson Med. 2021 11; 86(5):2810-2821. View Abstract
  81. Neuroimaging of the Preterm Brain: Review and Recommendations. J Pediatr. 2021 10; 237:276-287.e4. View Abstract
  82. White matter in infancy is prospectively associated with language outcomes in kindergarten. Dev Cogn Neurosci. 2021 08; 50:100973. View Abstract
  83. Motion Analysis in Fetal MRI using Deep Pose Estimator. Proc Int Soc Magn Reson Med Sci Meet Exhib Int Soc Magn Reson Med Sci Meet Exhib. 2021 May; 29. View Abstract
  84. Learning-based automatic field-of-view positioning for fetal-brain MRI. Proc Int Soc Magn Reson Med Sci Meet Exhib Int Soc Magn Reson Med Sci Meet Exhib. 2021 May; 29. View Abstract
  85. Quantification of magnetic resonance spectroscopy data using a combined reference: Application in typically developing infants. NMR Biomed. 2021 07; 34(7):e4520. View Abstract
  86. Targeting human milk fortification to improve very preterm infant growth and brain development: study protocol for Nourish, a single-center randomized, controlled clinical trial. BMC Pediatr. 2021 04 09; 21(1):167. View Abstract
  87. Abnormal Left-Hemispheric Sulcal Patterns in Adults With Simple Congenital Heart Defects Repaired in Childhood. J Am Heart Assoc. 2021 04 06; 10(7):e018580. View Abstract
  88. Intergenerational Transmission of Cortical Sulcal Patterns from Mothers to their Children. Cereb Cortex. 2021 03 05; 31(4):1888-1897. View Abstract
  89. Rapid head-pose detection for automated slice prescription of fetal-brain MRI. Int J Imaging Syst Technol. 2021 Sep; 31(3):1136-1154. View Abstract
  90. Development, validation, and pilot MRI safety study of a high-resolution, open source, whole body pediatric numerical simulation model. PLoS One. 2021; 16(1):e0241682. View Abstract
  91. De novo variants in MPP5 cause global developmental delay and behavioral changes. Hum Mol Genet. 2020 12 18; 29(20):3388-3401. View Abstract
  92. Voxelwise and Regional Brain Apparent Diffusion Coefficient Changes on MRI from Birth to 6 Years of Age. Radiology. 2021 02; 298(2):415-424. View Abstract
  93. Fetal Cortical Plate Segmentation Using Fully Convolutional Networks With Multiple Plane Aggregation. Front Neurosci. 2020; 14:591683. View Abstract
  94. Regional Brain Growth Trajectories in Fetuses with Congenital Heart Disease. Ann Neurol. 2021 01; 89(1):143-157. View Abstract
  95. Semi-Supervised Learning for Fetal Brain MRI Quality Assessment with ROI consistency. Med Image Comput Comput Assist Interv. 2020 Oct; 12266:386-395. View Abstract
  96. Enhanced detection of fetal pose in 3D MRI by Deep Reinforcement Learning with physical structure priors on anatomy. Med Image Comput Comput Assist Interv. 2020 Oct; 12266:396-405. View Abstract
  97. Brain Characteristics Noted Prior to and Following Cranial Orthotic Treatment. Child Neurol Open. 2020 Jan-Dec; 7:2329048X20949769. View Abstract
  98. Placental MRI: Development of an MRI compatible ex vivo system for whole placenta dual perfusion. Placenta. 2020 11; 101:4-12. View Abstract
  99. Identification of neuronal structures and pathways corresponding to clinical functioning in galactosemia. J Inherit Metab Dis. 2020 11; 43(6):1205-1218. View Abstract
  100. Detecting microstructural white matter abnormalities of frontal pathways in children with ADHD using advanced diffusion models. Brain Imaging Behav. 2020 Aug; 14(4):981-997. View Abstract
  101. Fetal pose estimation from volumetric MRI using generative adversarial network. Proc Int Soc Magn Reson Med Sci Meet Exhib Int Soc Magn Reson Med Sci Meet Exhib. 2020 Aug; 28. View Abstract
  102. An Atypical Sulcal Pattern in Children with Disorders of the Corpus Callosum and Its Relation to Behavioral Outcomes. Cereb Cortex. 2020 07 30; 30(9):4790-4799. View Abstract
  103. Spatiotemporal Differences in the Regional Cortical Plate and Subplate Volume Growth during Fetal Development. Cereb Cortex. 2020 06 30; 30(8):4438-4453. View Abstract
  104. Temporal Patterns of Emergence and Spatial Distribution of Sulcal Pits During Fetal Life. Cereb Cortex. 2020 06 01; 30(7):4257-4268. View Abstract
  105. BRAIN AGE ESTIMATION USING LSTM ON CHILDREN'S BRAIN MRI. Proc IEEE Int Symp Biomed Imaging. 2020 Apr; 2020:420-423. View Abstract
  106. Infant FreeSurfer: An automated segmentation and surface extraction pipeline for T1-weighted neuroimaging data of infants 0-2 years. Neuroimage. 2020 09; 218:116946. View Abstract
  107. Maternal Dietary Intake of Omega-3 Fatty Acids Correlates Positively with Regional Brain Volumes in 1-Month-Old Term Infants. Cereb Cortex. 2020 04 14; 30(4):2057-2069. View Abstract
  108. Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease. Cereb Cortex. 2020 03 21; 30(2):476-487. View Abstract
  109. Quantitative In vivo MRI Assessment of Structural Asymmetries and Sexual Dimorphism of Transient Fetal Compartments in the Human Brain. Cereb Cortex. 2020 03 14; 30(3):1752-1767. View Abstract
  110. A phenotypically severe, biochemically "silent" case of HIBCH deficiency in a newborn diagnosed by rapid whole exome sequencing and enzymatic testing. Am J Med Genet A. 2020 04; 182(4):780-784. View Abstract
  111. Longitudinal structural connectomic and rich-club analysis in adolescent mTBI reveals persistent, distributed brain alterations acutely through to one year post-injury. Sci Rep. 2019 12 11; 9(1):18833. View Abstract
  112. Mining multi-site clinical data to develop machine learning MRI biomarkers: application to neonatal hypoxic ischemic encephalopathy. J Transl Med. 2019 11 21; 17(1):385. View Abstract
  113. Individual variation in simulated fetal SAR assessed in multiple body models. Magn Reson Med. 2020 04; 83(4):1418-1428. View Abstract
  114. Placental Flattening via Volumetric Parameterization. Med Image Comput Comput Assist Interv. 2019 Oct; 11767:39-47. View Abstract
  115. Patient-Customized Oligonucleotide Therapy for a Rare Genetic Disease. N Engl J Med. 2019 10 24; 381(17):1644-1652. View Abstract
  116. Placental MRI: Developing Accurate Quantitative Measures of Oxygenation. Top Magn Reson Imaging. 2019 Oct; 28(5):285-297. View Abstract
  117. Preliminary evaluation of dynamic glucose enhanced MRI of the human placenta during glucose tolerance test. Quant Imaging Med Surg. 2019 Oct; 9(10):1619-1627. View Abstract
  118. Abnormalities in cerebral hemodynamics and changes with surgical intervention in neonates with congenital heart disease. J Thorac Cardiovasc Surg. 2020 05; 159(5):2012-2021. View Abstract
  119. Nutritive sucking abnormalities and brain microstructural abnormalities in infants with established brain injury: a pilot study. J Perinatol. 2019 11; 39(11):1498-1508. View Abstract
  120. Maturation of Corticospinal Tracts in Children With Hemiplegic Cerebral Palsy Assessed by Diffusion Tensor Imaging and Transcranial Magnetic Stimulation. Front Hum Neurosci. 2019; 13:254. View Abstract
  121. Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease. Cereb Cortex. 2019 07 22; 29(8):3605-3616. View Abstract
  122. Altered White Matter Organization in the TUBB3 E410K Syndrome. Cereb Cortex. 2019 07 22; 29(8):3561-3576. View Abstract
  123. Resting-State fMRI Networks in Children with Tuberous Sclerosis Complex. J Neuroimaging. 2019 11; 29(6):750-759. View Abstract
  124. Network structural dependency in the human connectome across the life-span. Netw Neurosci. 2019; 3(3):792-806. View Abstract
  125. Longitudinal Changes in Magnetic Resonance Spectroscopy in Pediatric Concussion: A Pilot Study. Front Neurol. 2019; 10:556. View Abstract
  126. TRActs constrained by UnderLying INfant anatomy (TRACULInA): An automated probabilistic tractography tool with anatomical priors for use in the newborn brain. Neuroimage. 2019 10 01; 199:1-17. View Abstract
  127. A novel missense mutation in TFAP2B associated with Char syndrome and central diabetes insipidus. Am J Med Genet A. 2019 07; 179(7):1299-1303. View Abstract
  128. Encephalopathy in neonates with subgaleal hemorrhage is a key predictor of outcome. Pediatr Res. 2019 08; 86(2):234-241. View Abstract
  129. Markerless high-frequency prospective motion correction for neuroanatomical MRI. Magn Reson Med. 2019 07; 82(1):126-144. View Abstract
  130. GABA Transaminase Deficiency With Survival Into Adulthood. J Child Neurol. 2019 03; 34(4):216-220. View Abstract
  131. Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification. Neuroimage. 2019 03; 188:473-482. View Abstract
  132. Developing a short-form of the Genetic Counselling Outcome Scale: The Genomics Outcome Scale. Eur J Med Genet. 2019 May; 62(5):324-334. View Abstract
  133. Field of View Normalization in Multi-Site Brain MRI. Neuroinformatics. 2018 10; 16(3-4):431-444. View Abstract
  134. Surgical resection of ripple onset predicts outcome in pediatric epilepsy. Ann Neurol. 2018 09; 84(3):331-346. View Abstract
  135. Disorganized Patterns of Sulcal Position in Fetal Brains with Agenesis of Corpus Callosum. Cereb Cortex. 2018 09 01; 28(9):3192-3203. View Abstract
  136. Clinical and Functional Characterization of the Recurrent TUBA1A p.(Arg2His) Mutation. Brain Sci. 2018 Aug 07; 8(8). View Abstract
  137. Exploring early human brain development with structural and physiological neuroimaging. Neuroimage. 2019 02 15; 187:226-254. View Abstract
  138. Publisher Correction: Shedding light on the neonatal brain: probing cerebral hemodynamics by diffuse optical spectroscopic methods. Sci Rep. 2018 Apr 12; 8(1):6007. View Abstract
  139. Quantitative Apparent Diffusion Coefficient Mapping May Predict Seizure Onset in Children With Sturge-Weber Syndrome. Pediatr Neurol. 2018 07; 84:32-38. View Abstract
  140. MNE Scan: Software for real-time processing of electrophysiological data. J Neurosci Methods. 2018 06 01; 303:55-67. View Abstract
  141. Sulcal pits and patterns in developing human brains. Neuroimage. 2019 01 15; 185:881-890. View Abstract
  142. Shedding light on the neonatal brain: probing cerebral hemodynamics by diffuse optical spectroscopic methods. Sci Rep. 2017 Nov 17; 7(1):15786. View Abstract
  143. Probabilistic tractography-based thalamic parcellation in healthy newborns and newborns with congenital heart disease. J Magn Reson Imaging. 2018 06; 47(6):1626-1637. View Abstract
  144. Can cerebellar and brainstem apparent diffusion coefficient (ADC) values predict neuromotor outcome in term neonates with hypoxic-ischemic encephalopathy (HIE) treated with hypothermia? PLoS One. 2017; 12(7):e0178510. View Abstract
  145. In Vivo Quantification of Placental Insufficiency by BOLD MRI: A Human Study. Sci Rep. 2017 06 16; 7(1):3713. View Abstract
  146. Frequency Diffeomorphisms for Efficient Image Registration. Inf Process Med Imaging. 2017 Jun; 10265:559-570. View Abstract
  147. Reusable Client-Side JavaScript Modules for Immersive Web-Based Real-Time Collaborative Neuroimage Visualization. Front Neuroinform. 2017; 11:32. View Abstract
  148. Using clinically acquired MRI to construct age-specific ADC atlases: Quantifying spatiotemporal ADC changes from birth to 6-year old. Hum Brain Mapp. 2017 06; 38(6):3052-3068. View Abstract
  149. Non-invasive Assessment of Cerebral Blood Flow and Oxygen Metabolism in Neonates during Hypothermic Cardiopulmonary Bypass: Feasibility and Clinical Implications. Sci Rep. 2017 03 09; 7:44117. View Abstract
  150. Assessing the effects of subject motion on T2 relaxation under spin tagging (TRUST) cerebral oxygenation measurements using volume navigators. Magn Reson Med. 2017 Dec; 78(6):2283-2289. View Abstract
  151. Spatiotemporal alignment of in utero BOLD-MRI series. J Magn Reson Imaging. 2017 08; 46(2):403-412. View Abstract
  152. White Matter Alterations in Infants at Risk for Developmental Dyslexia. Cereb Cortex. 2017 02 01; 27(2):1027-1036. View Abstract
  153. Current and Emerging Potential of Magnetoencephalography in the Detection and Localization of High-Frequency Oscillations in Epilepsy. Front Neurol. 2017; 8:14. View Abstract
  154. The Potential for Advanced Magnetic Resonance Neuroimaging Techniques in Pediatric Stroke Research. Pediatr Neurol. 2017 04; 69:24-36. View Abstract
  155. High-angular resolution diffusion imaging tractography of cerebellar pathways from newborns to young adults. Brain Behav. 2017 01; 7(1):e00589. View Abstract
  156. Temporal Registration in In-Utero Volumetric MRI Time Series. Med Image Comput Comput Assist Interv. 2016 Oct; 9902:54-62. View Abstract
  157. Stroke in Acquired and Congenital Heart Disease Patients and Its Relationship to Hospital Mortality and Lasting Neurologic Deficits. Pediatr Crit Care Med. 2016 10; 17(10):976-983. View Abstract
  158. Single-step quantitative susceptibility mapping with variational penalties. NMR Biomed. 2017 Apr; 30(4). View Abstract
  159. Real-time multi-channel monitoring of burst-suppression using neural network technology during pediatric status epilepticus treatment. Clin Neurophysiol. 2016 08; 127(8):2820-2831. View Abstract
  160. Reduced cerebral blood flow and oxygen metabolism in extremely preterm neonates with low-grade germinal matrix- intraventricular hemorrhage. Sci Rep. 2016 05 16; 6:25903. View Abstract
  161. Arterial Spin Labeling Perfusion Magnetic Resonance Imaging Performed in Acute Perinatal Stroke Reveals Hyperperfusion Associated With Ischemic Injury. Stroke. 2016 06; 47(6):1514-9. View Abstract
  162. Two unique TUBB3 mutations cause both CFEOM3 and malformations of cortical development. Am J Med Genet A. 2016 Feb; 170A(2):297-305. View Abstract
  163. Sturge-Weber Syndrome: Brain Magnetic Resonance Imaging and Neuropathology Findings. Pediatr Neurol. 2016 05; 58:25-30. View Abstract
  164. Brain extraction in pediatric ADC maps, toward characterizing neuro-development in multi-platform and multi-institution clinical images. Neuroimage. 2015 Nov 15; 122:246-61. View Abstract
  165. Failure to Identify the Left Arcuate Fasciculus at Diffusion Tractography Is a Specific Marker of Language Dysfunction in Pediatric Patients with Polymicrogyria. Behav Neurol. 2015; 2015:351391. View Abstract
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  167. Editorial on emerging neuroimaging tools for studying normal and abnormal human brain development. Front Hum Neurosci. 2015; 9:127. View Abstract
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  183. Cerebral oxygen metabolism in neonatal hypoxic ischemic encephalopathy during and after therapeutic hypothermia. J Cereb Blood Flow Metab. 2014 Jan; 34(1):87-94. View Abstract
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  187. Whole genome sequencing identifies SCN2A mutation in monozygotic twins with Ohtahara syndrome and unique neuropathologic findings. Epilepsia. 2013 May; 54(5):e81-5. View Abstract
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  191. A novel syndrome caused by the E410K amino acid substitution in the neuronal ß-tubulin isotype 3. Brain. 2013 Feb; 136(Pt 2):522-35. View Abstract
  192. Somatosensory evoked changes in cerebral oxygen consumption measured non-invasively in premature neonates. Neuroimage. 2014 Jan 15; 85 Pt 1:279-86. View Abstract
  193. Reliable identification of deep sulcal pits: the effects of scan session, scanner, and surface extraction tool. PLoS One. 2013; 8(1):e53678. View Abstract
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  195. Detection of postmortem human cerebellar cortex and white matter pathways using high angular resolution diffusion tractography: a feasibility study. Neuroimage. 2013 Mar; 68:105-11. View Abstract
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  202. Neuroanatomic connectivity of the human ascending arousal system critical to consciousness and its disorders. J Neuropathol Exp Neurol. 2012 Jun; 71(6):531-46. View Abstract
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  206. Altered fetal cerebral and cerebellar development in twin-twin transfusion syndrome. AJNR Am J Neuroradiol. 2012 Jun; 33(6):1121-6. View Abstract
  207. The confounding effect of systemic physiology on the hemodynamic response in newborns. Adv Exp Med Biol. 2012; 737:103-9. View Abstract
  208. Restricted diffusion in spinal cord infarction demonstrated by magnetic resonance line scan diffusion imaging. Stroke. 2012 Feb; 43(2):532-5. View Abstract
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  211. Multimodal imaging of spike propagation: a technical case report. AJNR Am J Neuroradiol. 2012 Jun; 33(6):E82-4. View Abstract
  212. Emerging cerebral connectivity in the human fetal brain: an MR tractography study. Cereb Cortex. 2012 Feb; 22(2):455-64. View Abstract
  213. Size-optimized 32-channel brain arrays for 3 T pediatric imaging. Magn Reson Med. 2011 Dec; 66(6):1777-87. View Abstract
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  218. Acute liver failure and reversible leukoencephalopathy in a pediatric patient with homocystinuria. J Pediatr Gastroenterol Nutr. 2010 Nov; 51(5):668-71. View Abstract
  219. Fetal MR imaging evidence of prolonged apparent diffusion coefficient decrease in fetal death. AJNR Am J Neuroradiol. 2011 Aug; 32(7):E126-8. View Abstract
  220. In vivo proton beam range verification using spine MRI changes. Int J Radiat Oncol Biol Phys. 2010 Sep 01; 78(1):268-75. View Abstract
  221. Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates' brains in the first six weeks of life. Hum Brain Mapp. 2010 Mar; 31(3):341-52. View Abstract
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  223. Tract-based analysis of callosal, projection, and association pathways in pediatric patients with multiple sclerosis: a preliminary study. AJNR Am J Neuroradiol. 2010 Jan; 31(1):121-8. View Abstract
  224. Associations between the size of the amygdala in infancy and language abilities during the preschool years in normally developing children. Neuroimage. 2010 Feb 01; 49(3):2791-9. View Abstract
  225. New directions in clinical imaging of cortical dysplasias. Epilepsia. 2009 Oct; 50 Suppl 9:9-18. View Abstract
  226. Development of cerebral fiber pathways in cats revealed by diffusion spectrum imaging. Neuroimage. 2010 Jan 15; 49(2):1231-40. View Abstract
  227. Changes in white matter microstructure in patients with TLE and hippocampal sclerosis. Epileptic Disord. 2009 Sep; 11(3):244-50. View Abstract
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  229. Case records of the Massachusetts General Hospital. Case 23-2009. A 13-year-old boy with headache, nausea, seizures, and hypertension. N Engl J Med. 2009 Jul 23; 361(4):389-400. View Abstract
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  231. Progressive multifocal cystlike cortical tubers in tuberous sclerosis complex: Clinical and neuropathologic findings. Epilepsia. 2009 Dec; 50(12):2648-51. View Abstract
  232. Predicting the location of entorhinal cortex from MRI. Neuroimage. 2009 Aug 01; 47(1):8-17. View Abstract
  233. Surveillance of craniopharyngioma cyst growth in children treated with proton radiotherapy. Int J Radiat Oncol Biol Phys. 2009 Mar 01; 73(3):716-21. View Abstract
  234. Case records of the Massachusetts General Hospital. Case 7-2009. A pregnant woman with a large mass in the fetal oral cavity. N Engl J Med. 2009 Feb 26; 360(9):913-21. View Abstract
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  236. Case records of the Massachusetts General Hospital. Case 28-2008. An 8-day-old infant with congenital deafness, lethargy, and hypothermia. N Engl J Med. 2008 Sep 11; 359(11):1156-67. View Abstract
  237. Shape analysis with overcomplete spherical wavelets. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):468-76. View Abstract
  238. Adriamycin injection into the medial cord of the brachial plexus: computed tomography-guided targeted pain therapy. Pain Med. 2008 Jan-Feb; 9(1):83-7. View Abstract
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  240. Magnetic resonance imaging evaluation of possible neonatal sinovenous thrombosis. Pediatr Neurol. 2007 Nov; 37(5):317-23. View Abstract
  241. Cortical Folding Development Study based on Over-Complete Spherical Wavelets. Proc IEEE Int Conf Comput Vis. 2007 Oct; 2007. View Abstract
  242. Magnetoencephalographic mapping of interictal spike propagation: a technical and clinical report. AJNR Am J Neuroradiol. 2007 Sep; 28(8):1486-8. View Abstract
  243. Assessment of infant brain development with frequency-domain near-infrared spectroscopy. Pediatr Res. 2007 May; 61(5 Pt 1):546-51. View Abstract
  244. Physiologic and radiographic evidence of the distal edge of the proton beam in craniospinal irradiation. Int J Radiat Oncol Biol Phys. 2007 Jul 01; 68(3):646-9. View Abstract
  245. Cortical surface shape analysis based on spherical wavelets. IEEE Trans Med Imaging. 2007 Apr; 26(4):582-97. View Abstract
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  247. Changes in cerebral cortex of children treated for medulloblastoma. Int J Radiat Oncol Biol Phys. 2007 Jul 15; 68(4):992-8. View Abstract
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  249. Proton magnetic resonance spectroscopy and diffusion-weighted imaging in isolated sulfite oxidase deficiency. J Child Neurol. 2006 Sep; 21(9):801-5. View Abstract
  250. Case records of the Massachusetts General Hospital. Case 26-2006. A 19-year-old woman with difficulty walking. N Engl J Med. 2006 Aug 24; 355(8):831-9. View Abstract
  251. Our unborn children at risk? Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12661-2. View Abstract
  252. Detailed semiautomated MRI based morphometry of the neonatal brain: preliminary results. Neuroimage. 2006 Sep; 32(3):1041-9. View Abstract
  253. Cortical Surface Shape Analysis Based on Spherical Wavelet Transformation. Conf Comput Vis Pattern Recognit Workshops. 2006 Jun; 2006. View Abstract
  254. Acute injury to the immature brain with hypoxia with or without hypoperfusion. Magn Reson Imaging Clin N Am. 2006 May; 14(2):271-85. View Abstract
  255. The value of multichannel MEG and EEG in the presurgical evaluation of 70 epilepsy patients. Epilepsy Res. 2006 Apr; 69(1):80-6. View Abstract
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  257. Acute injury to the immature brain with hypoxia with or without hypoperfusion. Radiol Clin North Am. 2006 Jan; 44(1):63-77, viii. View Abstract
  258. Case records of the Massachusetts General Hospital. Case 36-2005. A 61-year-old woman with seizure, disturbed gait, and altered mental status. N Engl J Med. 2005 Nov 24; 353(21):2271-80. View Abstract
  259. 3T phased array MRI improves the presurgical evaluation in focal epilepsies: a prospective study. Neurology. 2005 Oct 11; 65(7):1026-31. View Abstract
  260. Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature. Pediatrics. 2005 Sep; 116(3):757-66. View Abstract
  261. Pediatric stroke: the child is not merely a small adult. Neuroimaging Clin N Am. 2005 Aug; 15(3):589-607, xi. View Abstract
  262. Structural brain magnetic resonance imaging of limbic and thalamic volumes in pediatric bipolar disorder. Am J Psychiatry. 2005 Jul; 162(7):1256-65. View Abstract
  263. Can noninvasive imaging of biomarkers improve clinical grading of pediatric brain tumors? Nat Clin Pract Oncol. 2005 Jul; 2(7):336-7. View Abstract
  264. Dynamic statistical parametric mapping for analyzing the magnetoencephalographic epileptiform activity in patients with epilepsy. J Child Neurol. 2005 Apr; 20(4):363-9. View Abstract
  265. Imaging the developing epileptic brain. Epilepsia. 2005; 46 Suppl 7:7-14. View Abstract
  266. Parenchymal abnormalities associated with cerebral venous sinus thrombosis: assessment with diffusion-weighted MR imaging. AJNR Am J Neuroradiol. 2004 Nov-Dec; 25(10):1666-75. View Abstract
  267. Bilateral generalized polymicrogyria (BGP): a distinct syndrome of cortical malformation. Neurology. 2004 May 25; 62(10):1722-8. View Abstract
  268. Multimodal longitudinal imaging of focal status epilepticus. Can J Neurol Sci. 2004 May; 31(2):276-81. View Abstract
  269. Evolution of water diffusion and anisotropy in hyperacute stroke: significant correlation between fractional anisotropy and T2. AJNR Am J Neuroradiol. 2004 May; 25(5):699-705. View Abstract
  270. Structural MR imaging. Epilepsia. 2004; 45 Suppl 4:4-16. View Abstract
  271. Aids to telemetry in the presurgical evaluation of epilepsy patients: MRI, MEG and other non-invasive imaging techniques. Suppl Clin Neurophysiol. 2004; 57:494-502. View Abstract
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  276. A novel form of pontocerebellar hypoplasia maps to chromosome 7q11-21. Neurology. 2003 May 27; 60(10):1664-7. View Abstract
  277. Bilateral frontoparietal polymicrogyria: clinical and radiological features in 10 families with linkage to chromosome 16. Ann Neurol. 2003 May; 53(5):596-606. View Abstract
  278. Abnormal cortical development shown by 3D MRI in Prader-Willi syndrome. Neurology. 2002 Aug 27; 59(4):644-5. View Abstract
  279. Diffusion magnetic resonance imaging of acute ischemic stroke. Semin Roentgenol. 2002 Jul; 37(3):219-29. View Abstract
  280. Perfusion magnetic resonance imaging of acute ischemic stroke. Semin Roentgenol. 2002 Jul; 37(3):230-6. View Abstract
  281. Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology. 2002 Jun 25; 58(12):1726-38. View Abstract
  282. Arterial ischemic stroke in childhood: the role of plasma-phase risk factors. Curr Opin Neurol. 2002 Apr; 15(2):139-44. View Abstract
  283. Diffusion-weighted images in neonatal cerebral hypoxic-ischemic injury. Pediatr Neurol. 2002 Apr; 26(4):274-81. View Abstract
  284. An autosomal recessive form of bilateral frontoparietal polymicrogyria maps to chromosome 16q12.2-21. Am J Hum Genet. 2002 Apr; 70(4):1028-33. View Abstract
  285. Pediatric functional magnetic resonance imaging: progress and challenges. Top Magn Reson Imaging. 2002 Feb; 13(1):61-70. View Abstract
  286. Diffusion MR imaging of acute ischemic stroke. Neuroimaging Clin N Am. 2002 Feb; 12(1):35-53. View Abstract
  287. Frequency and clinical context of decreased apparent diffusion coefficient reversal in the human brain. Radiology. 2001 Oct; 221(1):43-50. View Abstract
  288. Diffusion-weighted MR imaging of the brain. Radiology. 2000 Nov; 217(2):331-45. View Abstract
  289. Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations. Nat Genet. 2000 Sep; 26(1):93-6. View Abstract
  290. MEG versus BOLD MR imaging: functional imaging, the next generation? AJNR Am J Neuroradiol. 2000 Sep; 21(8):1369-70. View Abstract
  291. Genetic and neuroradiological heterogeneity of double cortex syndrome. Ann Neurol. 2000 Feb; 47(2):265-9. View Abstract
  292. Diffusion MR imaging. Theory and applications. Neuroimaging Clin N Am. 1999 May; 9(2):343-61. View Abstract

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