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Research Overview

Dr. Michael Toce conducts research that focuses on pediatric toxicology and emergency medicine. He has published on the association of state opioid reduction policies with pediatric opioid poisonings and is currently focused on assessing the association of prescription drug monitoring programs with adolescent and young adult opioid prescribing and overdose. In addition to his work on opioids, Dr. Toce is investigating pediatric marijuana and anti-epileptic drug overdoses.

Research Background

Dr. Michael Toce completed his undergraduate studies at Carleton College where he received a B.A. in biology and biochemistry. He received a M.S. in bacteriology from the University of Wisconsin-Madison, and his M.D. from the Medical College of Wisconsin. He completed his pediatrics residency at the Boston Combined Residency Program before completing a Medical Toxicology Fellowship and Pediatric Emergency Medicine Fellowship at Boston Children's Hospital. He is currently an attending in the Boston Children's Hospital Emergency Department and works as a Medical Toxicologist at the MA/RI Poison Control Center.

Education

Undergraduate School

Carelton College
2004 Northfield MN

Graduate School

University of Wisconsin-Madison
2008 Madison WI

Medical School

Medical College of Wisconsin
2012 Milwaukee WI

Residency

Boston Combined Residency Program (BCRP)
2015 Boston MA

Fellowship

Harvard Medical Toxicology Program
2017 Boston MA

Fellowship

Pediatric Emergency Medicine Boston Children's Hospital
2019 Boston MA

Publications

  1. Naloxone Access Laws and Opioid-Related Overdose Deaths in Youths. JAMA Pediatr. 2024 Dec 01; 178(12):1368-1370. View Abstract
  2. The Association of the Child Opportunity Index with Emergency Department Presentations for Pediatric Poisonings: A Case-Control Study. J Pediatr. 2024 Nov 15; 277:114410. View Abstract
  3. Characteristics and Trends of Prehospital Encounters for Opioid Overdoses Among US Youth, 2018-2022. JAMA. 2024 10 15; 332(15):1299-1302. View Abstract
  4. Welcome to the 2024 ACMT Annual Scientific Meeting. J Med Toxicol. 2024 Apr; 20(2):84-85. View Abstract
  5. Resource utilization among children presenting with cannabis poisonings in the emergency department. Am J Emerg Med. 2023 Nov; 73:171-175. View Abstract
  6. Pediatric hand sanitizer exposures reported to United States poison centers, 2017-2021. Clin Toxicol (Phila). 2023 06; 61(6):463-469. View Abstract
  7. Association of prescription drug monitoring programs with benzodiazepine prescription dispensation and overdose in adolescents and young adults. Clin Toxicol (Phila). 2023 04; 61(4):234-240. View Abstract
  8. Welcome to the 2023 ACMT Annual Scientific Meeting-San Diego, CA. J Med Toxicol. 2023 Apr; 19(2):61-62. View Abstract
  9. Association of Prescription Drug Monitoring Programs With Opioid Prescribing and Overdose in Adolescents and Young Adults. Ann Emerg Med. 2023 04; 81(4):429-437. View Abstract
  10. Trends in Dispensing of Controlled Medications for US Adolescents and Young Adults, 2008 to 2019. JAMA Pediatr. 2022 12 01; 176(12):1265-1266. View Abstract
  11. Pediatric Melatonin Ingestions - United States, 2012-2021. MMWR Morb Mortal Wkly Rep. 2022 06 03; 71(22):725-729. View Abstract
  12. Trends in Benzodiazepine Prescribing for US Adolescents and Young Adults From 2008 to 2019. JAMA Pediatr. 2022 03 01; 176(3):312-313. View Abstract
  13. National assessment of anti-epileptic drug exposures among pre-teens and adolescents, 2000-2020. Clin Toxicol (Phila). 2022 06; 60(6):681-687. View Abstract
  14. Pediatric cannabis use and cardiac complications. CMAJ. 2021 11 15; 193(45):E1737. View Abstract
  15. COVID-19 and Pediatric Ingestions. Pediatrics. 2021 07; 148(1). View Abstract
  16. Commentary on Hill et al.: Breaking down barriers-increasing access to lifesaving opioid use disorder medications to save lives. Addiction. 2021 06; 116(6):1512-1513. View Abstract
  17. Clinical Effects of Pediatric Clonidine Exposure: A Retrospective Cohort Study at a Single Tertiary Care Center. J Emerg Med. 2021 Jan; 60(1):58-66. View Abstract
  18. Association of State-Level Opioid-Reduction Policies With Pediatric Opioid Poisoning. JAMA Pediatr. 2020 10 01; 174(10):961-968. View Abstract
  19. Neonate With Abdominal Distention. Ann Emerg Med. 2019 Apr; 73(4):e41-e42. View Abstract
  20. Case 1: A Medically Complex 10-month-old Boy with Lethargy. Pediatr Rev. 2019 Feb; 40(2):79-81. View Abstract
  21. Prolonged central apnoea after intravenous morphine administration in a 12-year-old male with a UGT1A1 loss-of-function polymorphism. Br J Clin Pharmacol. 2019 01; 85(1):258-262. View Abstract
  22. Pharmacologic Treatment of Opioid Use Disorder: a Review of Pharmacotherapy, Adjuncts, and Toxicity. J Med Toxicol. 2018 12; 14(4):306-322. View Abstract
  23. Myocardial Infarct After Marijuana Inhalation in a 16-year-old Adolescent Boy. Pediatr Dev Pathol. 2019 Jan-Feb; 22(1):80-86. View Abstract
  24. Acute Amnestic Syndrome Associated with Fentanyl Overdose. N Engl J Med. 2018 Mar 22; 378(12):1157-1158. View Abstract
  25. A case report of methadone-associated hypoglycemia in an 11-month-old male. Clin Toxicol (Phila). 2018 01; 56(1):74-76. View Abstract
  26. The Poisoned Pediatric Patient. Pediatr Rev. 2017 May; 38(5):207-220. View Abstract
  27. A Case Report of Reversible Takotsubo Cardiomyopathy after Amphetamine/Dextroamphetamine Ingestion in a 15-Year-Old Adolescent Girl. J Pediatr. 2017 03; 182:385-388.e3. View Abstract
  28. Clinical effects of unintentional pediatric buprenorphine exposures: experience at a single tertiary care center. Clin Toxicol (Phila). 2017 Jan; 55(1):12-17. View Abstract

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