Information

Related Research Units

Endocrinology Research

Research Overview

Dr. Stefater-Richards’ research focuses on understanding mechanisms behind effective treatments, especially bariatric surgery, for obesity and obesity-related comorbidities including Type 2 Diabetes. She is combining clinical/translational and basic approaches to answer these questions. Dr. Stefater-Richards sees patients in both the Endocrinology and Adolescent Bariatric Surgery programs, where she does clinical and translational research, in addition to her basic lab work which is focused on epigenetic mechanisms for intestinal remodeling after bariatric surgery.

Research Background

Dr. Stefater-Richards completed her B.A. degree at Northwestern University. She then obtained an MD/PhD at the University of Cincinnati, with a PhD in Neuroscience. She completed her pediatric training as well as a fellowship in Pediatric Endocrinology at Boston Children’s Hospital. Dr. Stefater-Richards trained with Dr. Nicholas Stylopoulos, MD, where she studied intestinal remodeling after Roux-en-Y gastric bypass surgery. She is funded by several internal and external mechanisms including an NIH K08 grant from the NIDDK.

Education

Undergraduate School

Northwestern University ,
2005 Evanston IL

Graduate School

University of Cincinnati
2010 Cincinnati OH

Medical School

University of Cincinnati
2012 Cincinnati OH

Internship

Pediatrics Boston Combined Residency Program (BCRP)
2013 Boston MA

Residency

Pediatrics Boston Combined Residency Program (BCRP)
2015 Boston MA

Fellowship

Pediatric Endocrinology Boston Children's Hospital
2018 Boston MA

Media

Parentcast Podcast

Dr. Margeret Stefater- is featured: Is weight loss medication an option for my teen?

Publications

  1. Gastric bypass elicits persistent gut adaptation and unique diabetes remission-related metabolic gene regulation. Obesity (Silver Spring). 2024 Nov; 32(11):2135-2148. View Abstract
  2. The enteroendocrine axis and its effect on gastrointestinal function, nutrition, and inflammation. Curr Opin Crit Care. 2024 Aug 01; 30(4):290-297. View Abstract
  3. Gut adaptation after gastric bypass in humans reveals metabolically significant shift in fuel metabolism. Obesity (Silver Spring). 2023 01; 31(1):49-61. View Abstract
  4. Gastric Bypass in an Adolescent with Obesity, Insulin Resistance, and Type 1 Diabetes. Obes Surg. 2021 May; 31(5):2298-2301. View Abstract
  5. Effect of Diet versus Gastric Bypass on Metabolic Function in Diabetes. N Engl J Med. 2020 12 10; 383(24):2391-2392. View Abstract
  6. Portal Venous Metabolite Profiling After RYGB in Male Rats Highlights Changes in Gut-Liver Axis. J Endocr Soc. 2020 Feb 01; 4(2):bvaa003. View Abstract
  7. Differential Metabolomic Signatures in Patients with Weight Regain and Sustained Weight Loss After Gastric Bypass Surgery: A Pilot Study. Dig Dis Sci. 2020 04; 65(4):1144-1154. View Abstract
  8. Comment on: GLP-1 and PYY3-36 reduce high-fat food preference additively after Roux-en-Y gastric bypass in diet-induced obese rats. Surg Obes Relat Dis. 2019 09; 15(9):1492-1493. View Abstract
  9. Glycogen storage disease presenting as Cushing syndrome. JIMD Rep. 2019 May; 47(1):17-22. View Abstract
  10. The Feasibility of Examining the Effects of Gastric Bypass Surgery on Intestinal Metabolism: Prospective, Longitudinal Mechanistic Clinical Trial. JMIR Res Protoc. 2019 Jan 24; 8(1):e12459. View Abstract
  11. Publisher Correction: Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018 Oct; 24(10):1628. View Abstract
  12. Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018 07; 24(7):1058-1069. View Abstract
  13. Bariatric Surgery for Adolescents with Type 2 Diabetes: an Emerging Therapeutic Strategy. Curr Diab Rep. 2017 08; 17(8):62. View Abstract
  14. A case report of methadone-associated hypoglycemia in an 11-month-old male. Clin Toxicol (Phila). 2018 01; 56(1):74-76. View Abstract
  15. Three-decade metabolic outcome of neonatal gastrectomy and early Roux-en-Y. Pediatr Surg Int. 2014 Feb; 30(2):249-52. View Abstract
  16. The anorectic effect of GLP-1 in rats is nutrient dependent. PLoS One. 2012; 7(12):e51870. View Abstract
  17. Advances in the surgical treatment of morbid obesity. Mol Aspects Med. 2013 Feb; 34(1):84-94. View Abstract
  18. Bariatric surgery for adolescents. Pediatr Diabetes. 2013 Feb; 14(1):1-12. View Abstract
  19. All bariatric surgeries are not created equal: insights from mechanistic comparisons. Endocr Rev. 2012 Aug; 33(4):595-622. View Abstract
  20. The anorectic effect of CNTF does not require action in leptin-responsive neurons. Endocrinology. 2012 Jun; 153(6):2647-54. View Abstract
  21. The effect of vertical sleeve gastrectomy on food choice in rats. Int J Obes (Lond). 2013 Feb; 37(2):288-95. View Abstract
  22. Molecular insights from bariatric surgery. Rev Endocr Metab Disord. 2011 Sep; 12(3):211-7. View Abstract
  23. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology. 2011 Sep; 141(3):950-8. View Abstract
  24. Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. Physiol Behav. 2011 Nov 30; 105(1):120-3. View Abstract
  25. Sleeve gastrectomy in rats improves postprandial lipid clearance by reducing intestinal triglyceride secretion. Gastroenterology. 2011 Sep; 141(3):939-949.e1-4. View Abstract
  26. Central nervous system nutrient signaling: the regulation of energy balance and the future of dietary therapies. Annu Rev Nutr. 2010 Aug 21; 30:219-35. View Abstract
  27. Sleeve gastrectomy induces loss of weight and fat mass in obese rats, but does not affect leptin sensitivity. Gastroenterology. 2010 Jun; 138(7):2426-36, 2436.e1-3. View Abstract

Contact Margaret Stefater-Richards

Phone: 617-919-6976
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