Margaret Kenna's research focuses on pediatric otology; currently, she is studying the underlying causes of sensorineural hearing loss (SNHL), the most common congenital sensory impairment. Her research includes the genetics of hearing loss, especially GJB2 (Connexin 26) and Usher syndrome; anatomic inner ear anomalies and vestibular function testing; and congenital cytomegalovirus infection. Dr. Kenna's earlier research focused on the causes and treatment of chronic suppurative otitis media (CSOM). She and her colleagues in Pittsburgh established that medical, not surgical therapy was very effective and should be the initial management option.
Research Background
Margaret Kenna received her MD degree from Boston University School of Medicine. She completed an internship and residency in Otolaryngology-Head and Neck Surgery at the University Hospital of Arkansas and a fellowship at in Pediatric Otolaryngology at the Children's Hospital of Pittsburgh. She received a MPH in Clinical Effectiveness from the Harvard School of Public Health in 2005.
Education
Medical School
Boston University School of Medicine
1979
Boston
MA
Internship
University Hospital of Arkansas
1980
Little Rock
AR
Residency
University Hospital of Arkansas
1983
Little Rock
AR
Fellowship
Children's Hospital of Pittsburgh
1984
Pittsburgh
PA
Graduate School
MPH
Harvard School of Public Health
2005
Boston
MA
Publications
Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes. NPJ Genom Med. 2024 Dec 02; 9(1):60. View Abstract
Management of Prenatal Expanded Genetic Carrier Screening Results for Autosomal Recessive Sensorineural Hearing Loss. Otolaryngol Head Neck Surg. 2024 Nov 10. View Abstract
Microbial DNA extraction method for avian feces and preen oil from diverse species. Ecol Evol. 2024 Sep; 14(9):e70220. View Abstract
Chromosomal structural rearrangements implicate long non-coding RNAs in rare germline disorders. Hum Genet. 2024 Jul; 143(7):921-938. View Abstract
Rare germline disorders implicate long non-coding RNAs disrupted by chromosomal structural rearrangements. medRxiv. 2024 Jun 19. View Abstract
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules. Science. 2024 Apr 26; 384(6694):eadf5489. View Abstract
PKHD1L1, a gene involved in the stereocilia coat, causes autosomal recessive nonsyndromic hearing loss. Hum Genet. 2024 Mar; 143(3):311-329. View Abstract
PKHD1L1, A Gene Involved in the Stereocilia Coat, Causes Autosomal Recessive Nonsyndromic Hearing Loss. medRxiv. 2023 Dec 19. View Abstract
Models of Classroom Assessment for Course-Based Research Experiences. Front Educ (Lausanne). 2023; 8:1279921. View Abstract
Programming Levels and Speech Perception in Pediatric Cochlear Implant Recipients With Enlarged Vestibular Aqueduct or GJB2 Mutation. Otol Neurotol. 2023 06 01; 44(5):e273-e280. View Abstract
Newborn Hearing Screening Results in Patients with Enlarged Vestibular Aqueduct. Laryngoscope. 2023 10; 133(10):2786-2791. View Abstract
Exome Sequencing Expands the Genetic Diagnostic Spectrum for Pediatric Hearing Loss. Laryngoscope. 2023 09; 133(9):2417-2424. View Abstract
Congenital Cytomegalovirus Screening in Massachusetts Birth Hospitals: A Statewide Survey. Int J Neonatal Screen. 2022 Dec 13; 8(4). View Abstract
Otolaryngologic Manifestations of Trisomy 13 and Trisomy 18 in Pediatric Patients. Laryngoscope. 2023 06; 133(6):1501-1506. View Abstract
Characterization of a possible founder synonymous variant in TECTA in multiple individuals with autosomal recessive hearing loss. Hum Mutat. 2022 12; 43(12):1837-1843. View Abstract
Genetic testing for pediatric hearing loss: no time to waste. Hum Genet. 2022 Apr; 141(3-4):315-317. View Abstract
In Response to, "Is revision of Cochlear Implants Infrequent?" Laryngoscope. 2022 05; 132(5):E17. View Abstract
Hearing Stability in Patients With Unilateral Hearing Loss Due to Congenital CMV. Otolaryngol Head Neck Surg. 2022 10; 167(4):739-744. View Abstract
Pain at the Cochlear Implant Site Requiring Device Removal in Pediatric Patients. Laryngoscope. 2022 10; 132(10):2044-2049. View Abstract
Evaluation of copy number variants for genetic hearing loss: a review of current approaches and recent findings. Hum Genet. 2022 Apr; 141(3-4):387-400. View Abstract
Peripheral Vestibular Dysfunction Is a Common Occurrence in Children With Non-syndromic and Syndromic Genetic Hearing Loss. Front Neurol. 2021; 12:714543. View Abstract
Comprehensive medical evaluation of pediatric bilateral sensorineural hearing loss. Laryngoscope Investig Otolaryngol. 2021 Oct; 6(5):1196-1207. View Abstract
Hearing Aid Use in Children With Unilateral Hearing Loss: A Randomized Crossover Clinical Trial. Laryngoscope. 2022 04; 132(4):881-888. View Abstract
Neuroimaging in Kabuki syndrome and another KMT2D-related disorder. Am J Med Genet A. 2021 12; 185(12):3770-3783. View Abstract
Hiding in plain sight: genetic deaf-blindness is not always Usher syndrome. Cold Spring Harb Mol Case Stud. 2021 08; 7(4). View Abstract
Pediatric Bilateral Sensorineural Hearing Loss: Minimum Test Battery and Referral Criteria for Cochlear Implant Candidacy Evaluation. Otolaryngol Head Neck Surg. 2022 03; 166(3):405-409. View Abstract
Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish. Genet Med. 2021 10; 23(10):1933-1943. View Abstract
Audiologic Phenotype and Progression in Pediatric STRC-Related Autosomal Recessive Hearing Loss. Laryngoscope. 2021 12; 131(12):E2897-E2903. View Abstract
Review of Hearing Loss in Children-Reply. JAMA. 2021 03 23; 325(12):1224-1225. View Abstract
Just Do It-Everyone Should Follow the Guidelines. JAMA Otolaryngol Head Neck Surg. 2021 03 01; 147(3):261-262. View Abstract
Incidence, Time Course, and Implications of Electrode Abnormalities in Pediatric Cochlear Implant Recipients. Ear Hear. 2021 Mar/Apr; 42(2):334-342. View Abstract
Dark-adapted threshold and electroretinogram for diagnosis of Usher syndrome. Doc Ophthalmol. 2021 08; 143(1):39-51. View Abstract
A synonymous variant in MYO15A enriched in the Ashkenazi Jewish population causes autosomal recessive hearing loss due to abnormal splicing. Eur J Hum Genet. 2021 06; 29(6):988-997. View Abstract
Hearing Loss in Children: A Review. JAMA. 2020 Dec 01; 324(21):2195-2205. View Abstract
Does Ibuprofen Increase Bleed Risk for Pediatric Tonsillectomy? Otolaryngol Head Neck Surg. 2021 07; 165(1):187-196. View Abstract
Women in Otolaryngology: Experiences of Being Female in the Specialty. Laryngoscope. 2021 02; 131(2):E380-E387. View Abstract
Validation of a Parent Proxy Quality-of-Life Measure for Young Children With Hearing Loss. Laryngoscope. 2021 03; 131(3):663-670. View Abstract
Genetics of pediatric hearing loss: A functional perspective. Laryngoscope Investig Otolaryngol. 2020 Jun; 5(3):511-519. View Abstract
Association of Blood Type With Postsurgical Mucosal Bleeding in Pediatric Patients Undergoing Tonsillectomy With or Without Adenoidectomy. JAMA Netw Open. 2020 03 02; 3(3):e201804. View Abstract
Perspective on the Development of a Large-Scale Clinical Data Repository for Pediatric Hearing Research. Ear Hear. 2020 Mar/Apr; 41(2):231-238. View Abstract
Preclinical testing of AAV9-PHP.B for transgene expression in the non-human primate cochlea. Hear Res. 2020 09 01; 394:107930. View Abstract
Torticollis in children with enlarged vestibular aqueducts. Int J Pediatr Otorhinolaryngol. 2020 Apr; 131:109862. View Abstract
Correction: ClinGen expert clinical validity curation of 164 hearing loss gene-disease pairs. Genet Med. 2019 Oct; 21(10):2409. View Abstract
Consensus interpretation of the p.Met34Thr and p.Val37Ile variants in GJB2 by the ClinGen Hearing Loss Expert Panel. Genet Med. 2019 11; 21(11):2442-2452. View Abstract
Genome Sequences of Six Cluster N Mycobacteriophages, Kevin1, Nenae, Parmesanjohn, ShrimpFriedEgg, Smurph, and SpongeBob, Isolated on Mycobacterium smegmatis mc2155. Microbiol Resour Announc. 2019 May 30; 8(22). View Abstract
A novel missense mutation in TFAP2B associated with Char syndrome and central diabetes insipidus. Am J Med Genet A. 2019 07; 179(7):1299-1303. View Abstract
ClinGen expert clinical validity curation of 164 hearing loss gene-disease pairs. Genet Med. 2019 10; 21(10):2239-2247. View Abstract
Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate. Mol Ther Methods Clin Dev. 2019 Jun 14; 13:1-13. View Abstract
Expert specification of the ACMG/AMP variant interpretation guidelines for genetic hearing loss. Hum Mutat. 2018 11; 39(11):1593-1613. View Abstract
Does Clarithromycin Cause Hearing Loss? A 12-Year Review of Clarithromycin Therapy for Nontuberculous Mycobacterial Lymphadenitis in Children. Ann Otol Rhinol Laryngol. 2018 Oct; 127(10):687-693. View Abstract
Ambulatory Visits for Otitis Media before and after the Introduction of Pneumococcal Conjugate Vaccination. J Pediatr. 2018 10; 201:122-127.e1. View Abstract
Postoperative Hearing Loss in a Patient With Crouzon Syndrome: A Case Report. A A Pract. 2018 Jun 01; 10(11):310-311. View Abstract
Revision cochlear implant surgery in children: Surgical and audiological outcomes. Laryngoscope. 2018 11; 128(11):2619-2624. View Abstract
Validation of a portable hearing assessment tool: Agilis Health Mobile Audiogram. Int J Pediatr Otorhinolaryngol. 2018 Oct; 113:94-98. View Abstract
Otolaryngologic Manifestations of Klippel-Feil Syndrome in Children. JAMA Otolaryngol Head Neck Surg. 2018 Mar 01; 144(3):238-243. View Abstract
Enlarged Vestibular Aqueduct and Cochlear Implants: The Effect of Early Counseling on the Length of Time Between Candidacy and Implantation. Otol Neurotol. 2018 02; 39(2):e90-e95. View Abstract
Eight Genome Sequences of Cluster BE1 Phages That Infect Streptomyces Species. Genome Announc. 2018 Jan 11; 6(2). View Abstract
Genome Sequences of Chancellor, Mitti, and Wintermute, Three Subcluster K4 Phages Isolated Using Mycobacterium smegmatis mc2155. Genome Announc. 2017 Nov 09; 5(45). View Abstract
Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages. PLoS One. 2017; 12(7):e0180517. View Abstract
Neurologic Evaluation in Children With Laryngeal Cleft. JAMA Otolaryngol Head Neck Surg. 2017 07 01; 143(7):651-655. View Abstract
Genome Sequences of Mycobacteriophages Jane and Sneeze, New Members of Cluster G. Genome Announc. 2017 Mar 16; 5(11). View Abstract
Genome Sequence of Cluster W Mycobacteriophage Taptic. Genome Announc. 2017 Mar 16; 5(11). View Abstract
Prophage-mediated defence against viral attack and viral counter-defence. Nat Microbiol. 2017 Jan 09; 2:16251. View Abstract
Acute Otitis Media - The Long and the Short of It. N Engl J Med. 2016 12 22; 375(25):2492-2493. View Abstract
Periodic Fever, Aphthosis, Pharyngitis, and Adenitis Syndrome: Analysis of Patients From Two Geographic Areas. Arthritis Care Res (Hoboken). 2016 12; 68(12):1859-1865. View Abstract
Hearing loss associated with enlarged vestibular aqueduct and zero or one mutant allele of SLC26A4. Laryngoscope. 2017 07; 127(7):E238-E243. View Abstract
International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Hearing loss in the pediatric patient. Int J Pediatr Otorhinolaryngol. 2016 Nov; 90:251-258. View Abstract
Risk Factors for Hearing Loss in Patients with Cystic Fibrosis. J Am Acad Audiol. 2016 01; 27(1):6-12. View Abstract
Atypical patterns of segregation of familial enlargement of the vestibular aqueduct. Laryngoscope. 2016 07; 126(7):E240-7. View Abstract
Acquired Hearing Loss in Children. Otolaryngol Clin North Am. 2015 Dec; 48(6):933-53. View Abstract
The Child with Hearing Loss. Otolaryngol Clin North Am. 2015 Dec; 48(6):xv-xvi. View Abstract
Peripheral vestibular loss detected in pediatric patients using a smartphone-based test of the subjective visual vertical. Int J Pediatr Otorhinolaryngol. 2015 Dec; 79(12):2094-8. View Abstract
The Public Health Impact of Pediatric Deep Neck Space Infections. Otolaryngol Head Neck Surg. 2015 Dec; 153(6):1036-41. View Abstract
Subjective visual vertical testing in children and adolescents. Laryngoscope. 2016 Mar; 126(3):727-31. View Abstract
What is the best non-codeine postadenotonsillectomy pain management for children? Laryngoscope. 2014 Aug; 124(8):1737-8. View Abstract
A121: in search of infectious triggers of periodic Fever, aphthous stomatitis, pharyngitis and adenitis syndrome. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S158. View Abstract
Use of SLC26A4 mutation testing for unilateral enlargement of the vestibular aqueduct. JAMA Otolaryngol Head Neck Surg. 2013 Sep; 139(9):907-13. View Abstract
3 µm CW lasers for myringotomy and microsurgery. Proc SPIE Int Soc Opt Eng. 2013 Mar 08; 8565. View Abstract
Pediatric sudden sensorineural hearing loss: diagnosed causes and response to intervention. Int J Pediatr Otorhinolaryngol. 2013 Apr; 77(4):553-9. View Abstract
Long-term surgical outcomes of adenotonsillectomy for PFAPA syndrome. Arch Otolaryngol Head Neck Surg. 2012 Oct; 138(10):902-6. View Abstract
Frequent association of cochlear nerve canal stenosis with pediatric sensorineural hearing loss. Arch Otolaryngol Head Neck Surg. 2012 Apr; 138(4):383-388. View Abstract
Prognosis tool based on a modified children's implant profile for use in pediatric cochlear implant candidacy evaluation. Ann Otol Rhinol Laryngol. 2012 Feb; 121(2):73-84. View Abstract
Genome-wide SNP genotyping identifies the Stereocilin (STRC) gene as a major contributor to pediatric bilateral sensorineural hearing impairment. Am J Med Genet A. 2012 Feb; 158A(2):298-308. View Abstract
Retinal disease course in Usher syndrome 1B due to MYO7A mutations. Invest Ophthalmol Vis Sci. 2011 Oct 07; 52(11):7924-36. View Abstract
Clinical experience in diagnosis and management of superior semicircular canal dehiscence in children. Laryngoscope. 2011 Oct; 121(10):2256-61. View Abstract
Comparison of postoperative pain in pediatric patients undergoing coblation tonsillectomy versus cautery tonsillectomy. Otolaryngol Head Neck Surg. 2011 Jun; 144(6):972-7. View Abstract
Histopathologic investigation of the dimensions of the cochlear nerve canal in normal temporal bones. Int J Pediatr Otorhinolaryngol. 2011 Apr; 75(4):464-7. View Abstract
Temporal bone abnormalities in children with GJB2 mutations. Laryngoscope. 2011 Mar; 121(3):630-5. View Abstract
Is computed tomography (CT) or magnetic resonance imaging (MRI) more useful in the evaluation of pediatric sensorineural hearing loss? Laryngoscope. 2010 Dec; 120(12):2358-9. View Abstract
Not a "sound" decision: is cochlear implantation always the best choice? Int J Pediatr Otorhinolaryngol. 2010 Oct; 74(10):1144-8. View Abstract
High-throughput detection of mutations responsible for childhood hearing loss using resequencing microarrays. BMC Biotechnol. 2010 Feb 10; 10:10. View Abstract
Posterior semicircular canal dehiscence: first reported case series. Otol Neurotol. 2010 Feb; 31(2):339-44. View Abstract
Audiologic phenotype and progression in GJB2 (Connexin 26) hearing loss. Arch Otolaryngol Head Neck Surg. 2010 Jan; 136(1):81-7. View Abstract
Sensorineural hearing loss in patients with cystic fibrosis. Otolaryngol Head Neck Surg. 2009 Jul; 141(1):86-90. View Abstract
Distinct and novel SLC26A4/Pendrin mutations in Chinese and U.S. patients with nonsyndromic hearing loss. Physiol Genomics. 2009 Aug 07; 38(3):281-90. View Abstract
Disturbance of vestibular function attributable to cochlear implantation in children. Laryngoscope. 2009 Apr; 119(4):740-5. View Abstract
Assessment of saccular function in children with sensorineural hearing loss. Arch Otolaryngol Head Neck Surg. 2009 Jan; 135(1):40-4. View Abstract
Delineating the hearing loss in children with enlarged vestibular aqueduct. Laryngoscope. 2008 Nov; 118(11):2062-6. View Abstract
Use of a preoperative bleeding questionnaire in pediatric patients who undergo adenotonsillectomy. Otolaryngol Head Neck Surg. 2008 Oct; 139(4):546-550. View Abstract
Phosphorylcholine-coated antibiotic tympanostomy tubes: are post-tube placement complications reduced? Int J Pediatr Otorhinolaryngol. 2008 Sep; 72(9):1323-8. View Abstract
Music to your ears: is it a good thing? Acta Paediatr. 2008 Feb; 97(2):151-2. View Abstract
Effect of adenotonsillectomy in PFAPA syndrome. Arch Otolaryngol Head Neck Surg. 2008 Feb; 134(2):136-40. View Abstract
Additional clinical manifestations in children with sensorineural hearing loss and biallelic GJB2 mutations: who should be offered GJB2 testing? Am J Med Genet A. 2007 Jul 15; 143A(14):1560-6. View Abstract
A multicenter study of the frequency and distribution of GJB2 and GJB6 mutations in a large North American cohort. Genet Med. 2007 Jul; 9(7):413-26. View Abstract
Anomalies of the middle and inner ear. Otolaryngol Clin North Am. 2007 Feb; 40(1):81-96, vi. View Abstract
The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering. Cell Cycle. 2007 Jan 01; 6(1):75-9. View Abstract
Intersection between the regulators of sister chromatid cohesion establishment and maintenance in budding yeast indicates a multi-step mechanism. Cell Cycle. 2006 Nov 01; 5(21):2528-36. View Abstract
Pediatric adenoidectomy: what is the effect of obstructive symptoms on the likelihood of future surgery? Int J Pediatr Otorhinolaryngol. 2006 Aug; 70(8):1467-72. View Abstract
The use of perioperative antibiotics in tonsillectomy: does it decrease morbidity? Int J Pediatr Otorhinolaryngol. 2006 May; 70(5):853-61. View Abstract
GJB2 mutations and degree of hearing loss: a multicenter study. Am J Hum Genet. 2005 Dec; 77(6):945-57. View Abstract
Pediatric facial nerve paralysis: patients, management and outcomes. Int J Pediatr Otorhinolaryngol. 2005 Nov; 69(11):1521-8. View Abstract
Otitis media and the new guidelines. J Otolaryngol. 2005 Jun; 34 Suppl 1:S24-32. View Abstract
Combined microtia and aural atresia: issues in cochlear implantation. Laryngoscope. 2005 Jan; 115(1):39-43. View Abstract
Medical management of childhood hearing loss. Pediatr Ann. 2004 Dec; 33(12):822-32. View Abstract
The spindle pole body assembly component mps3p/nep98p functions in sister chromatid cohesion. J Biol Chem. 2004 Nov 19; 279(47):49542-50. View Abstract
Clinical practice guideline: Otitis media with effusion. Otolaryngol Head Neck Surg. 2004 May; 130(5 Suppl):S95-118. View Abstract
Human EFO1p exhibits acetyltransferase activity and is a unique combination of linker histone and Ctf7p/Eco1p chromatid cohesion establishment domains. Nucleic Acids Res. 2003 Nov 01; 31(21):6334-43. View Abstract
Extraesophageal reflux in pediatric patients with upper respiratory symptoms. Arch Otolaryngol Head Neck Surg. 2003 Nov; 129(11):1213-20. View Abstract
Use of a multiplex PCR/sequencing strategy to detect both connexin 30 (GJB6) 342 kb deletion and connexin 26 (GJB2) mutations in cases of childhood deafness. Am J Med Genet A. 2003 Aug 30; 121A(2):102-8. View Abstract
Utility of tonsillectomy in 2 patients with the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. Arch Otolaryngol Head Neck Surg. 2003 Jun; 129(6):670-3. View Abstract
Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes. Mol Cell Biol. 2003 Apr; 23(8):2999-3007. View Abstract
The presentation and management of nasal dermoid: a 30-year experience. Arch Otolaryngol Head Neck Surg. 2003 Apr; 129(4):464-71. View Abstract
Effectiveness of sequencing connexin 26 (GJB2) in cases of familial or sporadic childhood deafness referred for molecular diagnostic testing. Genet Med. 2002 Jul-Aug; 4(4):279-88. View Abstract
The role of mitomycin in the prevention and treatment of scar formation in the pediatric aerodigestive tract: friend or foe? Arch Otolaryngol Head Neck Surg. 2002 Apr; 128(4):401-6. View Abstract
Congenital absence of the incus bilaterally without other otologic anomalies: a new case report. Ear Nose Throat J. 2002 Apr; 81(4):274-6, 278. View Abstract
Connexin 26 studies in patients with sensorineural hearing loss. Arch Otolaryngol Head Neck Surg. 2001 Sep; 127(9):1037-42. View Abstract
Mediastinitis associated with foreign body erosion of the esophagus in children. Int J Pediatr Otorhinolaryngol. 2001 Jun 07; 59(2):89-97. View Abstract
Craniofacial, temporal bone, and audiologic abnormalities in the spectrum of hemifacial microsomia. Arch Otolaryngol Head Neck Surg. 2001 Mar; 127(3):265-71. View Abstract
The relationship between dental overbite and eustachian tube dysfunction. Laryngoscope. 2001 Feb; 111(2):310-6. View Abstract
Airway foreign bodies (FB): a 10-year review. Int J Pediatr Otorhinolaryngol. 2000 Dec 01; 56(2):91-9. View Abstract
Intraoperative recurrent laryngeal nerve monitoring during video-assisted throracoscopic surgery for patent ductus arteriosus. J Cardiothorac Vasc Anesth. 2000 Oct; 14(5):562-4. View Abstract
Otitis media: the otolaryngologist's perspective. Pediatr Ann. 2000 Oct; 29(10):630-6. View Abstract
Pathology forum: quiz case 1. Diagnosis: posttransplant lymphoproliferative disease (PTLD) of the epiglottis. Arch Otolaryngol Head Neck Surg. 2000 Sep; 126(9):1153; discussion 1157-8. View Abstract
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6658-63. View Abstract
Don't rely on the surgical airway: a case of impossible tracheostomy. Paediatr Anaesth. 2000; 10(2):224-5. View Abstract
Cochlear implants and the deaf child: a nursing perspective. Pediatr Nurs. 1999 Jul-Aug; 25(4):396-400, 444. View Abstract
Acupressure-acupuncture antiemetic prophylaxis in children undergoing tonsillectomy. Anesthesiology. 1999 May; 90(5):1311-6. View Abstract
Causes of pediatric sensorineural hearing loss: yesterday and today. Arch Otolaryngol Head Neck Surg. 1999 May; 125(5):517-21. View Abstract
Necrotizing fasciitis of the pharynx following adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 1999 Apr 25; 48(1):1-7. View Abstract
Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology. J Neuropathol Exp Neurol. 1998 Dec; 57(12):1190-201. View Abstract
Treatment of chronic suppurative otitis media with topical ciprofloxacin. Ann Otol Rhinol Laryngol. 1998 Oct; 107(10 Pt 1):865-71. View Abstract
Comparison of spectral gradient acoustic reflectometry and other diagnostic techniques for detection of middle ear effusion in children with middle ear disease. Pediatr Infect Dis J. 1998 Jun; 17(6):556-9; discussion 580. View Abstract
Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo. Mol Cell Biol. 1998 Feb; 18(2):1115-24. View Abstract
Cochlear implantation in children. Nurs Clin North Am. 1997 Mar; 32(1):97-107. View Abstract
Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol. 1996 May; 16(5):2025-36. View Abstract
In vitro susceptibility of aural isolates of Pseudomonas aeruginosa to commonly used ototopical antibiotics. Am J Otol. 1996 Mar; 17(2):207-9. View Abstract
Therapeutic implications in the treatment of aural Pseudomonas infections based on in vitro susceptibility patterns. Arch Otolaryngol Head Neck Surg. 1995 Sep; 121(9):1022-5. View Abstract
Pathologic quiz case 1. Granular cell tumor (GCT) of larynx. Arch Otolaryngol Head Neck Surg. 1995 Sep; 121(9):1058, 1060-1. View Abstract
Head and neck manifestations of Beckwith-Wiedemann syndrome. Otolaryngol Head Neck Surg. 1995 Sep; 113(3):262-5. View Abstract
Correlation of beta-2 transferrin and middle ear abnormalities in congenital perilymphatic fistula. Am J Otol. 1995 May; 16(3):277-82. View Abstract
Consultation with the specialist. Hoarseness. Pediatr Rev. 1995 Feb; 16(2):69-72. View Abstract
Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. J Cell Biol. 1994 Aug; 126(3):619-30. View Abstract
Treatment of chronic suppurative otitis media. Otolaryngol Clin North Am. 1994 Jun; 27(3):457-72. View Abstract
Sensorineural hearing loss from quinolinic acid: a neurotoxin in middle ear effusions. Laryngoscope. 1994 Feb; 104(2):176-81. View Abstract
Medical management of chronic suppurative otitis media without cholesteatoma in children--update 1992. Am J Otol. 1993 Sep; 14(5):469-73. View Abstract
Laryngeal cysts: a cause of neonatal airway obstruction. Otolaryngol Head Neck Surg. 1993 Jul; 109(1):129-34. View Abstract
An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity. Mol Cell Biol. 1993 Jan; 13(1):341-50. View Abstract
Adenotonsillectomy for upper airway obstruction carries increased risk in children with a history of prematurity. Pediatr Pulmonol. 1992 Aug; 13(4):222-6. View Abstract
The effect of gastroesophageal reflux on the pediatric airway. Int Anesthesiol Clin. 1992; 30(4):83-91. View Abstract
Surgical management of tracheal stenosis in an infant with multiple congenital anomalies: when is baby inoperable? Ann Otol Rhinol Laryngol. 1991 Mar; 100(3):198-200. View Abstract
Congenital perilymphatic fistula: an overlooked diagnosis? Am J Otol. 1989 Nov; 10(6):496-8. View Abstract
The structure of a primitive kinetochore. Trends Biochem Sci. 1989 Jun; 14(6):223-7. View Abstract
Cis- and trans-acting factors affecting the structure of yeast centromeres. J Cell Sci Suppl. 1989; 12:231-42. View Abstract
Selective excision of the centromere chromatin complex from Saccharomyces cerevisiae. J Cell Biol. 1988 Jul; 107(1):9-15. View Abstract
Foreign bodies in the air and food passages. Pediatr Rev. 1988 Jul; 10(1):25-31. View Abstract
Refractory torticollis: an uncommon complication of adenotonsillectomy. Int J Pediatr Otorhinolaryngol. 1987 Dec; 14(2-3):87-93. View Abstract
Cefixime vs. cefaclor in the treatment of acute otitis media in infants and children. Pediatr Infect Dis J. 1987 Oct; 6(10):992-6. View Abstract
Prognostic value of eustachian tube function in pediatric tympanoplasty. Laryngoscope. 1987 Sep; 97(9):1012-6. View Abstract
Tracheotomy in the preterm infant. Ann Otol Rhinol Laryngol. 1987 Jan-Feb; 96(1 Pt 1):68-71. View Abstract
Duration of intubation in children with acute epiglottitis. Otolaryngol Head Neck Surg. 1986 Nov; 95(4):477-81. View Abstract
Junctional epidermolysis bullosa of the larynx. Pediatrics. 1986 Jul; 78(1):172-4. View Abstract
Microbiology of chronic suppurative otitis media in children. Pediatr Infect Dis. 1986 Mar-Apr; 5(2):223-5. View Abstract
Complication of acute epiglottitis. Int J Pediatr Otorhinolaryngol. 1986 Feb; 11(1):67-71. View Abstract
Medical management of chronic suppurative otitis media without cholesteatoma in children. Laryngoscope. 1986 Feb; 96(2):146-51. View Abstract
Nasal surgery in children with cystic fibrosis: complications and risk management. Laryngoscope. 1985 Dec; 95(12):1491-3. View Abstract
Consensus: management of the child with a chronic draining ear. Pediatr Infect Dis. 1985 Nov-Dec; 4(6):607-12. View Abstract
Tidal flow measurement in the decision to decannulate the pediatric patient. Ann Otol Rhinol Laryngol. 1985 Sep-Oct; 94(5 Pt 1):454-7. View Abstract
Amplification and elevated expression of c-myc in a chemically induced mouse colon tumor. Cancer Res. 1985 Sep; 45(9):4433-8. View Abstract
Effectiveness of hydrotreatment in reducing the toxicity of a coal liquefaction product to juvenile channel catfish. Bull Environ Contam Toxicol. 1985 May; 34(5):746-53. View Abstract
Nasal papillomas and squamous carcinoma. Am Fam Physician. 1984 Sep; 30(3):171-5. View Abstract
Chronic suppurative otitis media: antimicrobial therapy or surgery? Pediatr Ann. 1984 May; 13(5):417-21. View Abstract
Malignant granular cell tumor of the tongue. Arch Otolaryngol. 1982 Sep; 108(9):603-5. View Abstract
Concanavalin A-mediated binding and sphering of human red blood cells by homologous monocytes. J Exp Med. 1976 Dec 01; 144(6):1695-700. View Abstract
Effect of papain on the interaction between human monocytes, erythrocytes, and IgG. Blood. 1975 Aug; 46(2):245-52. View Abstract