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Related Research Units

Research Overview

Dr. Olson's research focuses on examining parameters that effect the detection of disease outbreaks that are relatively small in size but characterized by spatial clustering. Detection algorithms are evaluated by inserting simulated clusters that vary on parameters of interest into historical data from hospital emergency departments.

Research Background

Karen Olson received her PhD from Wayne State University. She completed post-doctoral work at the University of Geneva, Switzerland, and the University of Regensburg, Germany.

Selected Publications

  1. Olson KL, Bonetti M, Pagano M, Mandl KD. Real time spatial cluster detection using interpoint distances among precise patient locations. BMC Medical Informatics and Decision Making, 2005, 5:19.
  2. Olson KL, Bonetti M, Pagano M, Mandl KD. A population- adjusted stable geospatial baseline for outbreak detection in syndromic surveillance. Morbidity and Mortality Weekly Report, Syndromic Surveillance Reports, 2004, 53:231.
  3. Beitel AJ, Olson KL, Reis BY, Mandl KD. Use of emergency department chief complaint and diagnostic codes for identifying respiratory illness in a pediatric population. Pediatric Emergency Care, 2004, 20:355-360.

Publications

  1. Moving Biosurveillance Beyond Coded Data Using AI for Symptom Detection From Physician Notes: Retrospective Cohort Study. J Med Internet Res. 2024 Apr 04; 26:e53367. View Abstract
  2. Emergency department visits and boarding for pediatric patients with suicidality before and during the COVID-19 pandemic. PLoS One. 2023; 18(11):e0286035. View Abstract
  3. Engaging a national-scale cohort of smart thermometer users in participatory surveillance. NPJ Digit Med. 2023 Sep 20; 6(1):175. View Abstract
  4. Smart Thermometer-Based Participatory Surveillance to Discern the Role of Children in Household Viral Transmission During the COVID-19 Pandemic. JAMA Netw Open. 2023 06 01; 6(6):e2316190. View Abstract
  5. Association of prescription drug monitoring programs with benzodiazepine prescription dispensation and overdose in adolescents and young adults. Clin Toxicol (Phila). 2023 04; 61(4):234-240. View Abstract
  6. Association of Prescription Drug Monitoring Programs With Opioid Prescribing and Overdose in Adolescents and Young Adults. Ann Emerg Med. 2023 04; 81(4):429-437. View Abstract
  7. Acute respiratory distress syndrome after SARS-CoV-2 infection on young adult population: International observational federated study based on electronic health records through the 4CE consortium. PLoS One. 2023; 18(1):e0266985. View Abstract
  8. Trends in Dispensing of Controlled Medications for US Adolescents and Young Adults, 2008 to 2019. JAMA Pediatr. 2022 12 01; 176(12):1265-1266. View Abstract
  9. Trends in Benzodiazepine Prescribing for US Adolescents and Young Adults From 2008 to 2019. JAMA Pediatr. 2022 03 01; 176(3):312-313. View Abstract
  10. Validation of an internationally derived patient severity phenotype to support COVID-19 analytics from electronic health record data. J Am Med Inform Assoc. 2021 07 14; 28(7):1411-1420. View Abstract
  11. Patients dispensed medications with actionable pharmacogenomic biomarkers: rates and characteristics. Genet Med. 2021 04; 23(4):782-786. View Abstract
  12. NICU Network Neurobehavioral Scale: 1-month normative data and variation from birth to 1 month. Pediatr Res. 2018 06; 83(6):1104-1109. View Abstract
  13. Patients Visiting Multiple Emergency Departments: Patterns, Costs, and Risk Factors. Acad Emerg Med. 2017 11; 24(11):1349-1357. View Abstract
  14. Provider Connectedness to Other Providers Reduces Risk of Readmission After Hospitalization for Heart Failure. Med Care Res Rev. 2019 02; 76(1):115-128. View Abstract
  15. The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis. Drug Saf. 2017 03; 40(3):263-272. View Abstract
  16. Prevalence and Characteristics of Interventional Trials Conducted Exclusively in Elderly Persons: A Cross-Sectional Analysis of Registered Clinical Trials. PLoS One. 2016; 11(5):e0155948. View Abstract
  17. Erratum to: Provider patient-sharing networks and multiple-provider prescribing of benzodiazepines. J Gen Intern Med. 2016 May; 31(5):588. View Abstract
  18. Drug-Drug Interactions Among Hospitalized Children Receiving Chronic Antiepileptic Drug Therapy. Hosp Pediatr. 2016 May; 6(5):282-9. View Abstract
  19. Infants, mothers, and dyadic contributions to stability and prediction of social stress response at 6 months. Dev Psychol. 2016 Jan; 52(1):1-8. View Abstract
  20. Comparison of Drug Utilization Patterns in Observational Data: Antiepileptic Drugs in Pediatric Patients. Paediatr Drugs. 2015 Oct; 17(5):401-10. View Abstract
  21. Provider Patient-Sharing Networks and Multiple-Provider Prescribing of Benzodiazepines. J Gen Intern Med. 2016 Feb; 31(2):164-171. View Abstract
  22. Provider collaboration: cohesion, constellations, and shared patients. J Gen Intern Med. 2014 Nov; 29(11):1499-505. View Abstract
  23. Association between pediatric clinical trials and global burden of disease. Pediatrics. 2014 Jan; 133(1):78-87. View Abstract
  24. Pediatric versus adult drug trials for conditions with high pediatric disease burden. Pediatrics. 2012 Aug; 130(2):285-92. View Abstract
  25. Temporal patterns of medications dispensed to children and adolescents in a national insured population. PLoS One. 2012; 7(7):e40991. View Abstract
  26. Healthy newborns' neurobehavior: norms and relations to medical and demographic factors. J Pediatr. 2012 Dec; 161(6):1073-9. View Abstract
  27. A pharmacoepidemiological network model for drug safety surveillance: statins and rhabdomyolysis. Drug Saf. 2012 May 01; 35(5):395-406. View Abstract
  28. Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children. Arch Pediatr Adolesc Med. 2011 Jan; 165(1):61-7. View Abstract
  29. Patients treated at multiple acute health care facilities: quantifying information fragmentation. Arch Intern Med. 2010 Dec 13; 170(22):1989-95. View Abstract
  30. The modern paediatric injury pyramid: injuries in Massachusetts children and adolescents. Inj Prev. 2010 Apr; 16(2):123-6. View Abstract
  31. Use of population health data to refine diagnostic decision-making for pertussis. J Am Med Inform Assoc. 2010 Jan-Feb; 17(1):85-90. View Abstract
  32. EFFECTS OF MATERNAL DEPRESSION AND PANIC DISORDER ON MOTHER-INFANT INTERACTIVE BEHAVIOR IN THE FACE-TO-FACE STILL-FACE PARADIGM. Infant Ment Health J. 2008 Sep; 29(5):472-491. View Abstract
  33. Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial. J Med Internet Res. 2008 Mar 14; 10(1):e5. View Abstract
  34. A Still-face Paradigm for Young Children: 2½ Year-olds' Reactions to Maternal Unavailability during the Still-face. J Dev Process. 2008; 3(1):4-22. View Abstract
  35. Patients treated across multiple sites of care: a case for personally controlled health records. AMIA Annu Symp Proc. 2007 Oct 11; 881. View Abstract
  36. AEGIS: a robust and scalable real-time public health surveillance system. J Am Med Inform Assoc. 2007 Sep-Oct; 14(5):581-8. View Abstract
  37. Privacy protection versus cluster detection in spatial epidemiology. Am J Public Health. 2006 Nov; 96(11):2002-8. View Abstract
  38. Making up is hard to do, especially for mothers with high levels of depressive symptoms and their infant sons. J Child Psychol Psychiatry. 2006 Jul; 47(7):670-83. View Abstract
  39. Lumbar puncture ordering and results in the pediatric population: a promising data source for surveillance systems. Acad Emerg Med. 2006 Jul; 13(7):767-73. View Abstract
  40. Validation of syndromic surveillance for respiratory infections. Ann Emerg Med. 2006 Mar; 47(3):265.e1. View Abstract
  41. A software tool for creating simulated outbreaks to benchmark surveillance systems. BMC Med Inform Decis Mak. 2005 Jul 14; 5:22. View Abstract
  42. Real time spatial cluster detection using interpoint distances among precise patient locations. BMC Med Inform Decis Mak. 2005 Jun 21; 5:19. View Abstract
  43. Use of emergency department chief complaint and diagnostic codes for identifying respiratory illness in a pediatric population. Pediatr Emerg Care. 2004 Jun; 20(6):355-60. View Abstract
  44. Similar and functionally typical kinematic reaching parameters in 7- and 15-month-old in utero cocaine-exposed and unexposed infants. Dev Psychobiol. 2004 Apr; 44(3):168-75. View Abstract
  45. Normative neurobehavioral performance of healthy infants on the Neonatal Intensive Care Unit Network Neurobehavioral Scale. Pediatrics. 2004 Mar; 113(3 Pt 2):676-8. View Abstract
  46. Prevalence, stability, and socio-demographic correlates of depressive symptoms in Black mothers during the first 18 months postpartum. Matern Child Health J. 2003 Sep; 7(3):157-68. View Abstract
  47. Stability and change in level of maternal depressive symptomatology during the first postpartum year. J Affect Disord. 2002 Sep; 71(1-3):169-80. View Abstract
  48. Subsyndromal depressive symptoms and major depression in postpartum women. Am J Orthopsychiatry. 2001 Jan; 71(1):87-97. View Abstract
  49. Gender differences in emotional expressivity and self-regulation during early infancy. Dev Psychol. 1999 Jan; 35(1):175-88. View Abstract
  50. Quality of prenatal care; selected social, behavioral, and biomedical factors; and birth weight. Obstet Gynecol. 1990 Apr; 75(4):607-12. View Abstract
  51. Effects of naloxone on ethanol dependence in rats. Drug Alcohol Depend. 1984 May; 13(3):245-54. View Abstract

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