Pediatric Anesthesia and Critical Care
Boston Children's Hospital
2001
Boston
MA
Fellowship
Research
Boston Children's Hospital
2002
Boston
MA
Publications
Formulation of Quality Improvement Methodology for Risk Mitigation in Congenital Cardiac Catheterization. Pediatr Cardiol. 2025 Jan 14. View Abstract
Neutrophil extracellular traps formation is associated with postoperative complications in congenital cardiac surgery. Pediatr Res. 2024 Nov 11. View Abstract
Thromboelastography-guided Intraoperative Platelet Transfusion in Pediatric Heart Surgery. Ann Thorac Surg. 2024 12; 118(6):1271-1278. View Abstract
Perioperative Hyper-coagulation and Thrombosis: Cost Analysis After Congenital Heart Surgery. Pediatr Cardiol. 2024 Jun 20. View Abstract
Barriers to healthcare access for children with congenital heart disease in eight Latin American countries. Paediatr Anaesth. 2024 09; 34(9):893-905. View Abstract
Neutrophil extracellular traps formation is associated with postoperative complications in neonates and infants undergoing congenital cardiac surgery. bioRxiv. 2023 Dec 23. View Abstract
Synonymous ADAMTS13 variants impact molecular characteristics and contribute to variability in active protein abundance. Blood Adv. 2022 09 27; 6(18):5364-5378. View Abstract
Implications of Transfusion in Adults with Congenital Heart Disease Undergoing Cardiac Surgery. Pediatr Cardiol. 2023 Jan; 44(1):218-227. View Abstract
ICU Admission Tool for Congenital Heart Catheterization (iCATCH): A Predictive Model for High Level Post-Catheterization Care and Patient Management. Pediatr Crit Care Med. 2022 10 01; 23(10):822-830. View Abstract
Contribution of ADAMTS13-independent VWF regulation in sickle cell disease. J Thromb Haemost. 2022 09; 20(9):2098-2108. View Abstract
Clinical implications of acute shunt thrombosis in paediatric patients with systemic-to-pulmonary shunt re-interventions. Cardiol Young. 2023 May; 33(5):726-732. View Abstract
Definitive Closure of the Patent Ductus Arteriosus in Preterm Infants and Subsequent Short-Term Respiratory Outcomes. Respir Care. 2022 05; 67(5):594-606. View Abstract
Comparison of Thromboelastography Devices TEG®6S Point of Care Device vs. TEG®5000 in Pediatric Patients Undergoing Cardiac Surgery. J Extra Corpor Technol. 2022 Mar; 54(1):42-49. View Abstract
Safety and feasibility of the paediatric post-cardiac catheterisation Wrap: a pilot study. Cardiol Young. 2023 Jan; 33(1):11-20. View Abstract
Plasma and Platelet Transfusions Strategies in Neonates and Children Undergoing Cardiac Surgery With Cardiopulmonary Bypass or Neonates and Children Supported by Extracorporeal Membrane Oxygenation: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding. Pediatr Crit Care Med. 2022 01 01; 23(13 Supple 1 1S):e25-e36. View Abstract
Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding (TAXI-CAB). Pediatr Crit Care Med. 2022 01 01; 23(1):34-51. View Abstract
Phenotyping respiratory decompensation following definitive closure of the patent ductus arteriosus in preterm infants. J Perinatol. 2022 05; 42(5):649-654. View Abstract
Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage. Genome Med. 2021 07 28; 13(1):122. View Abstract
In Silico Evaluation of Cyclophilin Inhibitors as Potential Treatment for SARS-CoV-2. Open Forum Infect Dis. 2021 Jun; 8(6):ofab189. View Abstract
Thromboelastography During Rewarming for Management of Pediatric Cardiac Surgery Patients. Ann Thorac Surg. 2022 04; 113(4):1248-1255. View Abstract
Coagulopathy and Thrombosis as a Result of Severe COVID-19 Infection: A Microvascular Focus. Thromb Haemost. 2020 Dec; 120(12):1668-1679. View Abstract
In silico features of ADAMTS13 contributing to plasmatic ADAMTS13 levels in neonates with congenital heart disease. Thromb Res. 2020 09; 193:66-76. View Abstract
TissueCoCoPUTs: Novel Human Tissue-Specific Codon and Codon-Pair Usage Tables Based on Differential Tissue Gene Expression. J Mol Biol. 2020 05 15; 432(11):3369-3378. View Abstract
Magnetic Resonance-Based Diagnostics for Bleeding Assessment in Neonatal Cardiac Surgery. Ann Thorac Surg. 2020 06; 109(6):1931-1936. View Abstract
Transition from Hemochron Response to Hemochron Signature Elite Activated Clotting Time Devices in a Congenital Cardiac Surgery Practice. J Extra Corpor Technol. 2019 Dec; 51(4):221-226. View Abstract
A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity. Int J Mol Sci. 2019 Nov 15; 20(22). View Abstract
Results of a phase 1 multicentre investigation of dexmedetomidine bolus and infusion in corrective infant cardiac surgery. Br J Anaesth. 2019 12; 123(6):839-852. View Abstract
Translational and transcriptional responses in human primary hepatocytes under hypoxia. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G720-G734. View Abstract
von Willebrand factor/ADAMTS-13 interactions at birth: implications for thrombosis in the neonatal period. J Thromb Haemost. 2019 Mar; 17(3):429-440. View Abstract
Thromboelastography Is Associated With Surrogates for Bleeding After Pediatric Cardiac Operations. Ann Thorac Surg. 2018 09; 106(3):799-806. View Abstract
A red cell preservation strategy reduces postoperative transfusions in pediatric heart surgery patients. Paediatr Anaesth. 2018 05; 28(5):450-457. View Abstract
Preoperative Thromboelastographic Profile of Patients with Congenital Heart Disease: Association of Hypercoagulability and Decreased Heparin Response. J Cardiothorac Vasc Anesth. 2018 08; 32(4):1657-1663. View Abstract
Elevated preoperative von Willebrand factor is associated with perioperative thrombosis in infants and neonates with congenital heart disease. J Thromb Haemost. 2017 12; 15(12):2306-2316. View Abstract
Compounding variants rescue the effect of a deleterious ADAMTS13 mutation in a child with severe congenital heart disease. Thromb Res. 2017 10; 158:98-101. View Abstract
Relationship Between Transfusion of Blood Products and the Incidence of Thrombotic Complications in Neonates and Infants Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. 2017 Dec; 31(6):1943-1948. View Abstract
Hypoxic preconditioning decreases nuclear factor ?B activity via Disrupted in Schizophrenia-1. Int J Biochem Cell Biol. 2016 Jan; 70:140-8. View Abstract
Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. Exp Mol Pathol. 2013 Dec; 95(3):350-56. View Abstract
Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. Exp Mol Pathol. 2013 Oct 25. View Abstract
ß-Ionone arrests cell cycle of gastric carcinoma cancer cells by a MAPK pathway. Arch Toxicol. 2013 Oct; 87(10):1797-808. View Abstract
Apoptosis initiation of ß-ionone in SGC-7901 gastric carcinoma cancer cells via a PI3K-AKT pathway. Arch Toxicol. 2013 Mar; 87(3):481-90. View Abstract
Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain. Anesthesiology. 2010 May; 112(5):1155-63. View Abstract
Disrupted in Schizophrenia-1 (DISC1)Regulates ATM-mediated NFkappaB Activation during Hypoxia and Re-oxygenation. FASEB meeting. 2010. View Abstract
Dexmedetomidine is less pro-apoptotic than ketamine in the neonatal rat brain. ASA. 2009. View Abstract
Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation. J Biol Chem. 2009 May 15; 284(20):13686-13695. View Abstract
Adenosine signaling mediates small ubiquitin-like protein (sumo-1) modification of IKappaBalpha during hypoxia and re-oxygenation. In press, Journal of Biological Chemistry. 2009. View Abstract
Anesthesia for Pediatric Thoracic Surgery. Springer Science and Business Media ( Phillip Hartigan). 2009. View Abstract
Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. 2009; 4(1):11-16. View Abstract
Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. Curr Drug Saf. 2009 Jan; 4(1):11-6. View Abstract
Noxious Stimulation Attenuates Ketamine and Isoflurane-Induced Neuroapoptosis in the P7 Rat Brain. ASA, 2008. 2008. View Abstract
Ketamine Activates Cell Cycle Events and Apoptosis in the Neonatal Rat Brain. ASA, 2008. 2008. View Abstract
Pulmonary anti-inflammatory adaptation to hypoxia through adenosine-mediated Cullin-1 Deneddylation. ASA, San Francisco CA. 2007. View Abstract
Central Venous Access in the Neonate. 2007. View Abstract
Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol. 2007 Jun 15; 178(12):8127-37. View Abstract
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. FASEB meeting, 2007. Washington DC. 2007. View Abstract
Identification of ecto-nucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol, In press. 2007. View Abstract
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J Clin Invest. 2007 Mar; 117(3):703-11. View Abstract
Mechanical Ventilation of the Neonate. Cambridge Press. 2007. View Abstract
Early tracheal extubation after liver or multivisceral transplantation in infant and toddler recipients: Is it safe?. ASA. 2006. View Abstract
Transcriptional Repression of Na-K-2Cl-cotransporter NKCC1 by Hypoxia Inducible Factor-1. AJP. Cell Physiol. 2006; 291:C282-C289. View Abstract
Identification of Molecular Anti-inflammatory Mechanisms of Adenosine: Cullin-1 Denedddylation during Hypoxic Preconditioning. 8th International Symposium on Adenosine and Adenine Nucleotides. 2006. View Abstract
Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. Blood. 2006 Sep 01; 108(5):1602-10. View Abstract
Endothelial Catabolism of Extracellular Adenosine during Hypoxia: Role of Surface Adenosine Deaminase and CD26. Blood. Epub ahead of print. 2006. View Abstract
HIF-dependent Repression of Na-K-2Clcotransporter (NKCC1) in Hypoxia. FASEB meeting 2006. San Francisco CA. 2006. View Abstract
Transcriptional repression of Na-K-2Cl cotransporter NKCC1 by hypoxia-inducible factor-1. Am J Physiol Cell Physiol. 2006 Aug; 291(2):C282-9. View Abstract
Anesthetic Management of a Patient with Hepatopulmonary Syndrome, Prolonged QTc Interval and Panhypopituitarism for Liver Transplantation. Society of Pediatric Anesthesia meeting. 2006. View Abstract
Transcriptional Repression of Na-K-2Cl-cotransporter (NKCC1) by Hypoxia Inducible Factor 1. Keystone Symposia. 2005. View Abstract
Anesthesia for Emergent non-cardiac Surgery in neonates with Unpalliated Hypoplastic Left Heart Syndrome. SPA/AAP. 2005. View Abstract
Methods in Molecular Biology. Methods to Assess
Tissue Permeability. Cell-Cell Interactions. 2005; 341:111-117. View Abstract
Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med. 2004 Dec 06; 200(11):1395-405. View Abstract
Critical Role for ecto-5'nucleotidase in pulmonary vascular permeability during hypoxia. ASA. 2004. View Abstract
Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood. 2004 Dec 15; 104(13):3986-92. View Abstract
The dynamic influences of hypoxia on extracellular nucleotide metabolism and nucleoside signalling. Purines 2004. 2004. View Abstract
Prolonged Ketamine Administration increases brain derived neurotrophic factor in developing rat brains. 2003. View Abstract
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med. 2003 Sep 01; 198(5):783-96. View Abstract
Implications of hypoxia on mucosal barrier function. Cell Mol Biol (Noisy-le-grand). 2003 Feb; 49(1):77-87. View Abstract
Lung growth after reduced size transplantation in a sheep model. Transplantation. 1999 Jan 27; 67(2):233-40. View Abstract
The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. J Pediatr Surg. 1998 Jul; 33(7):1038-41; discussion 1041-2. View Abstract
Insulin-like growth factor-I gene expression in three models of accelerated lung growth. J Pediatr Surg. 1998 Jul; 33(7):1057-60; discussion 1061. View Abstract
Lung growth following reduced-size lung transplantation in a sheep model. 1998. View Abstract
Pulmonary blood flow distribution during partial liquid ventilation. J Appl Physiol (1985). 1998 May; 84(5):1540-50. View Abstract
Insulin like growth factor I gene expression in three models of accelerated lung growth. 1997. View Abstract
The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. 1997. View Abstract
Effects of nitric oxide on hyperinflation-induced pulmonary hypertension in the isolated-perfused lung. Crit Care Med. 1996 Aug; 24(8):1388-95. View Abstract
Continuos intrapulmonary distention with perfluorocarbon does not result in postnatal lung growth in adult sheep. 1996. View Abstract
Redistribution of pulmonary blood flow during partial liquid ventilation. 1996. View Abstract
University of Wisconsin cerebroplegia in a piglet survival model of circulatory arrest. Ann Thorac Surg. 1995 Dec; 60(6 Suppl):S494-500. View Abstract
The effect of nitric oxide on overdistention pulmonary hypertension in the isolated sheep lung model. 1995. View Abstract
Limb fractures associated with craneoencephalic trauma. 1991. View Abstract