Information

Related Research Units

Newborn Medicine Research
Respiratory Diseases Research

Research Overview

Dr. Levin aims to utilize his background in biomedical informatics to study former preterm infants who have respiratory disease and to improve their care. Through the National Library of Medicine Biomedical Informatics and Data Science Research Training Program, he completed additional post-doctoral masters training at Harvard Medical School in Biomedical Informatics.

With this background, Dr. Levin serves in the role as co-chair for the data committee for the BPD collaborative, managing an international registry for this rare disease. He has lead work using the registry to predict tracheostomy in preterm infants using ventilator data at key points during the hospitalization, develop markers to track disease progression and improvement over the hospitalization, and evaluate which nutritional strategies lead to the best outcomes for these infants. Locally, Dr. Levin is part of the Boston Children's Hospital Preterm Lung Disease Registry and has conducted studies evaluating how care in the NICU impacts longer-term respiratory and developmental outcomes in this population.

Using data from these retrospective studies, Dr. Levin is currently funded to conduct a randomized crossover trial to study impact of postpyloric feeding on respiratory health in preterm infants at risk of lung disease.

Dr. Levin is also conducting work in remote patient monitoring in technology dependent infants and children with bronchopulmonary dysplasia who reside at home. In particular, he is interested in how remote data can improve how respiratory support is managed, and if signals in data can serve as early-warning signing for respiratory illnesses and allow earlier intervention to avoid hospitalization.

Research Background

Dr. Levin is a dual trained neonatologist and pediatric pulmonologist. At Boston Children's, he is the director of the BPD program and co-director of the pulmonary home ventilator program. His focus is in the provision of longitudinal care for infants and children with neonatal lung diseases, including BPD, from their time in the NICU through discharge and into childhood. He is also the co-data chair of the BPD collaborative. His research interests include using data analytics to help predict outcomes in BPD and identifying optimal ventilatory and nutritional strategies to support healthy lung development.

Education

Undergraduate School

Brown University
2008 Providence RI

Medical School

Yale School of Medicine
2013 New Haven CT

Internship

Pediatrics Boston Combined Residency Program
2014 Boston MA

Residency

Pediatrics Boston Combined Residency Program
2016 Boston MA

Fellowship

Boston Children's Hospital
2020 Boston MA

Publications

  1. Liberation from Respiratory Support in Bronchopulmonary Dysplasia. J Pediatr. 2024 Nov 07; 114390. View Abstract
  2. Outpatient clinical care for bronchopulmonary dysplasia: A survey of the BPD collaborative. Pediatr Pulmonol. 2025 Jan; 60(1):e27296. View Abstract
  3. Outcomes of infants and children with bronchopulmonary dysplasia-associated pulmonary hypertension who required home ventilation. Pediatr Res. 2024 Aug 24. View Abstract
  4. Factors associated with liberation from home mechanical ventilation and tracheostomy decannulation in infants and children with severe bronchopulmonary dysplasia. J Perinatol. 2024 Jul 31. View Abstract
  5. Transpyloric feeding is associated with adverse in-hospital outcomes in infants with severe bronchopulmonary dysplasia. J Perinatol. 2024 02; 44(2):307-313. View Abstract
  6. Number of children in the household influences respiratory morbidities in children with bronchopulmonary dysplasia in the outpatient setting. Pediatr Pulmonol. 2024 Feb; 59(2):314-322. View Abstract
  7. To Trach or Not To Trach: Long-term Tracheostomy Outcomes in Infants with BPD. Neoreviews. 2023 Nov 01; 24(11):e704-e719. View Abstract
  8. Pre-Flight Hypoxemia Challenge Testing in Bronchopulmonary Dysplasia. Pediatrics. 2023 08 01; 152(2). View Abstract
  9. Classifying multicenter approaches to invasive mechanical ventilation for infants with bronchopulmonary dysplasia using hierarchical clustering analysis. Pediatr Pulmonol. 2023 Aug; 58(8):2323-2332. View Abstract
  10. Respiratory Outcomes for Ventilator-Dependent Children With Bronchopulmonary Dysplasia. Pediatrics. 2023 05 01; 151(5). View Abstract
  11. Beyond the NICU: Comprehensive management of infants with bronchopulmonary dysplasia in the PICU. Pediatr Pulmonol. 2023 05; 58(5):1602-1606. View Abstract
  12. Prediction of extubation failure among low birthweight neonates using machine learning. J Perinatol. 2023 02; 43(2):209-214. View Abstract
  13. Tracheostomy in a Preterm Infant with Severe Bronchopulmonary Dysplasia. Neoreviews. 2022 10 01; 23(10):e708-e715. View Abstract
  14. Discharge Practices for Infants with Bronchopulmonary Dysplasia: A Survey of National Experts. J Pediatr. 2023 02; 253:72-78.e3. View Abstract
  15. Association of Racial Disparities With In-Hospital Outcomes in Severe Bronchopulmonary Dysplasia. JAMA Pediatr. 2022 09 01; 176(9):852-859. View Abstract
  16. Daycare Attendance is Linked to Increased Risk of Respiratory Morbidities in Children Born Preterm with Bronchopulmonary Dysplasia. J Pediatr. 2022 10; 249:22-28.e1. View Abstract
  17. Summary for Clinicians: Clinical Practice Guidelines for Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease. Ann Am Thorac Soc. 2022 06; 19(6):873-879. View Abstract
  18. Cost Savings Without Increased Risk of Respiratory Hospitalization for Preterm Children after the 2014 Palivizumab Policy Update. Am J Perinatol. 2024 05; 41(S 01):e133-e141. View Abstract
  19. Insurance coverage and respiratory morbidities in bronchopulmonary dysplasia. Pediatr Pulmonol. 2022 07; 57(7):1735-1743. View Abstract
  20. Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med. 2021 12 15; 204(12):e115-e133. View Abstract
  21. Long-term respiratory and developmental outcomes in children with bronchopulmonary dysplasia and history of tracheostomy. J Perinatol. 2021 11; 41(11):2645-2650. View Abstract
  22. Lung function trajectories in children with post-prematurity respiratory disease: identifying risk factors for abnormal growth. Respir Res. 2021 May 10; 22(1):143. View Abstract
  23. Medication utilization in children born preterm in the first two years of life. J Perinatol. 2021 07; 41(7):1732-1738. View Abstract
  24. COVID-19: neonatal-perinatal perspectives. J Perinatol. 2021 05; 41(5):940-951. View Abstract
  25. Apnea in the Otherwise Healthy, Term Newborn: National Prevalence and Utilization during the Birth Hospitalization. J Pediatr. 2017 02; 181:67-73.e1. View Abstract

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