Research Overview

Dr. Peyton is currently designing a trial looking at the use of Neosaxitoxin, a novel local anesthetic agent, in peripheral nerve blocks.

 

Education

Medical School

MBChB University of Bristol
Bristol United Kingdom

Fellowship

Pediatric Anesthesia Harvard University and Boston Children’s Hospital
Boston MA

Publications

  1. Airway Management Practices and Outcomes Over Time in Neonates and Young Infants Presenting for Cardiac Procedures. J Cardiothorac Vasc Anesth. 2026 Mar; 40(3):864-872. View Abstract
  2. Choice of Anesthetic Maintenance Is Not Merely a Matter of Preference, but One of Safety: Insights from the AmPRAEC Study. Anesthesiology. 2025 Dec 01; 143(6):1440-1442. View Abstract
  3. Use of supraglottic airways in neonates and infants less than 2 months old and role in difficult mask ventilation: a single-centre retrospective cohort study. Br J Anaesth. 2026 Jan; 136(1):367-370. View Abstract
  4. Should Not Anesthesia Research Involve Anesthesiologists? Consequences of the Decline in Academic Anesthesia and Possible Solutions. Anesth Analg. 2026 Feb 01; 142(2):293-298. View Abstract
  5. The fewer the better or the more the merrier? The challenges of large research collaborations. Anaesthesia. 2025 Dec; 80(12):1458-1461. View Abstract
  6. Consensus recommendations for paediatric airway topicalisation using lidocaine. Anaesthesia. 2025 Oct; 80(10):1237-1246. View Abstract
  7. Incidence of cognitive errors in difficult airway management: an inference human factors study from the Pediatric Difficult Intubation Registry. Br J Anaesth. 2025 Nov; 135(5):1499-1510. View Abstract
  8. Comparing videolaryngoscopy and flexible bronchoscopy to rescue failed direct laryngoscopy in children: a propensity score matched analysis of the Pediatric Difficult Intubation Registry. Anaesthesia. 2025 Jun; 80(6):625-635. View Abstract
  9. Videolaryngoscopy in neonates is not a matter of perspective. Eur J Anaesthesiol. 2025 Apr 01; 42(4):371-372. View Abstract
  10. Coaching inexperienced clinicians before a high stakes medical procedure: randomized clinical trial. BMJ. 2024 12 16; 387:e080924. View Abstract
  11. Awake Supraglottic Airway Placement in Pediatric Patients for Airway Obstruction or Difficult Intubation: Insights From an International Airway Registry (PeDI). Anesth Analg. 2025 Feb 01; 140(2):310-316. View Abstract
  12. Propofol, Anesthesia, and Neurocognitive Outcomes in Patients With Pediatric Leukemia: Are We Missing the Forest for the Trees? J Clin Oncol. 2024 Oct 10; 42(29):3506-3507. View Abstract
  13. Best practices in cognitive aid design for clinical emergencies. Response to Br J Anaesth 2024; 132: 1007-8. Br J Anaesth. 2024 Jun; 132(6):1345. View Abstract
  14. Airway management in the paediatric difficult intubation registry: a propensity score matched analysis of outcomes over time. EClinicalMedicine. 2024 Mar; 69:102461. View Abstract
  15. Airway management in neonates and infants: European Society of Anaesthesiology and Intensive Care and British Journal of Anaesthesia joint guidelines. Eur J Anaesthesiol. 2024 01 01; 41(1):3-23. View Abstract
  16. Airway management in neonates and infants: European Society of Anaesthesiology and Intensive Care and British Journal of Anaesthesia joint guidelines. Br J Anaesth. 2024 Jan; 132(1):124-144. View Abstract
  17. Airway topicalization in pediatric anesthesia: An international cross-sectional study. Paediatr Anaesth. 2024 02; 34(2):145-152. View Abstract
  18. Video laryngoscopy is not the nemesis of direct laryngoscopy. Lancet Respir Med. 2023 10; 11(10):e84. View Abstract
  19. Efficacy of a hybrid technique of simultaneous videolaryngoscopy with flexible bronchoscopy in children with difficult direct laryngoscopy in the Pediatric Difficult Intubation Registry. Anaesthesia. 2023 09; 78(9):1093-1101. View Abstract
  20. In the Director's Chair: Screen Time, Coaching, and Intubation in the PICU. Crit Care Med. 2023 07 01; 51(7):981-983. View Abstract
  21. Laryngoscopy-the times they are a-changin', and so should we. Paediatr Anaesth. 2023 06; 33(6):419-421. View Abstract
  22. Difficult or impossible facemask ventilation in children with difficult tracheal intubation: a retrospective analysis of the PeDI registry. Br J Anaesth. 2023 07; 131(1):178-187. View Abstract
  23. Practice Guidelines for Difficult Airway Management: Comment. Anesthesiology. 2022 10 01; 137(4):514. View Abstract
  24. Videolaryngoscopes versus direct laryngoscopes in children: Ranking systematic review with network meta-analyses of randomized clinical trials. Paediatr Anaesth. 2022 09; 32(9):1000-1014. View Abstract
  25. Someday we'll look back on this, and it will all seem funny. The lung and ventilation special issue 2030 and beyond. Paediatr Anaesth. 2022 Feb; 32(2):105-107. View Abstract
  26. Anesthesia for pediatric rigid bronchoscopy and related airway surgery: Tips and tricks. Paediatr Anaesth. 2022 Feb; 32(2):302-311. View Abstract
  27. Difficult tracheal intubation and perioperative outcomes in patients with congenital heart disease: A retrospective study. J Clin Anesth. 2022 02; 76:110565. View Abstract
  28. Pediatric Airway Anatomy and Tracheal Tubes: It Is Not All About the Cuff. Anesth Analg. 2021 10 01; 133(4):891-893. View Abstract
  29. Error traps in pediatric difficult airway management. Paediatr Anaesth. 2021 Dec; 31(12):1271-1275. View Abstract
  30. Comparing standard and non-standard videolaryngoscopes in children: methodological issues. Response to Br J Anaesth 2021; 127: e52-e4. Br J Anaesth. 2021 11; 127(5):e172-e173. View Abstract
  31. Lessons from COVID-19: A reflection on the strengths and weakness of early consensus recommendations for pediatric difficult airway management during a respiratory viral pandemic using a modified Delphi method. Paediatr Anaesth. 2021 10; 31(10):1074-1088. View Abstract
  32. Pediatric Airway Management in Times of COVID-19-a Review of the Evidence and Controversies. Curr Anesthesiol Rep. 2021; 11(3):243-247. View Abstract
  33. Trends in Pediatric MRI sedation/anesthesia at a tertiary medical center over time. Paediatr Anaesth. 2021 Sep; 31(9):953-961. View Abstract
  34. Aerosol barriers in pediatric anesthesiology: Clinical data supports FDA caution. Paediatr Anaesth. 2021 04; 31(4):461-464. View Abstract
  35. Risk of Hypoxemia by Induction Technique Among Infants and Neonates Undergoing Pyloromyotomy. Anesth Analg. 2021 02 01; 132(2):367-373. View Abstract
  36. Supraglottic airway and aerosol generation: Reality or simulation? Resuscitation. 2021 03; 160:172-173. View Abstract
  37. First-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial. Lancet. 2020 12 12; 396(10266):1905-1913. View Abstract
  38. A comparison of videolaryngoscopy using standard blades or non-standard blades in children in the Paediatric Difficult Intubation Registry. Br J Anaesth. 2021 Jan; 126(1):331-339. View Abstract
  39. Airway Abnormalities in Patients With Congenital Heart Disease: Incidence and Associated Factors. J Cardiothorac Vasc Anesth. 2021 Jan; 35(1):139-144. View Abstract
  40. Response to: Biphasic cuirass model. Paediatr Anaesth. 2020 07; 30(7):846-847. View Abstract
  41. The plural of anecdote is not data, please mind the gap between virtual and real life. Paediatr Anaesth. 2020 07; 30(7):732-733. View Abstract
  42. Pediatric Airway Management in COVID-19 Patients: Consensus Guidelines From the Society for Pediatric Anesthesia's Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society. Anesth Analg. 2020 07; 131(1):61-73. View Abstract
  43. What's inside the box? Or shall we think outside the box? Paediatr Anaesth. 2020 07; 30(7):734-736. View Abstract
  44. More on Barrier Enclosure during Endotracheal Intubation. N Engl J Med. 2020 05 21; 382(21):e69. View Abstract
  45. Pediatric laryngoscopy and bronchoscopy during the COVID-19 pandemic: A four-center collaborative protocol to improve safety with perioperative management strategies and creation of a surgical tent with disposable drapes. Int J Pediatr Otorhinolaryngol. 2020 Jul; 134:110059. View Abstract
  46. Anesthesia for shared airway surgery in children. Paediatr Anaesth. 2020 03; 30(3):288-295. View Abstract
  47. If you think you can do it, that's confidence: If you do it that's competence-Where are we in pediatric anesthesia? Paediatr Anaesth. 2019 10; 29(10):981-982. View Abstract
  48. Neonatal Airway Management. Clin Perinatol. 2019 12; 46(4):745-763. View Abstract
  49. The efficacy of GlideScope® videolaryngoscopy compared with direct laryngoscopy in children who are difficult to intubate: an analysis from the paediatric difficult intubation registry. Br J Anaesth. 2017 Nov 01; 119(5):984-992. View Abstract
  50. Videolaryngoscopy versus Fiber-optic Intubation through a Supraglottic Airway in Children with a Difficult Airway: An Analysis from the Multicenter Pediatric Difficult Intubation Registry. Anesthesiology. 2017 09; 127(3):432-440. View Abstract
  51. The pretracheal stethoscope useful, but not a necessity. Paediatr Anaesth. 2016 Mar; 26(3):256-8. View Abstract
  52. A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia. Anesthesiology. 2015 Oct; 123(4):873-85. View Abstract

Contact James M. Peyton