Research Overview

Dr. Thaker has a special research interest in neurogenic bladder and the development of novel neurotoxins for various bladder conditions. His basic science efforts are currently supported by the American Urological Association, SUFU, and the Office of Faculty Development at Harvard Medical School.

Publications

  [2]https://connects.catalyst.harvard.edu/Profiles/display/Person/181144

  [3]https://www.ncbi.nlm.nih.gov/myncbi/1-Im5fm1pM2QK/bibliography/public/

Education

Undergraduate School

Northwestern University
2010 Evanston IL

Medical School

University of Illinois at Chicago College of Medicine
2014 Chicago IL

Internship

Department of Surgery University of Southern California, LAC+USC
2015 Los Angeles CA

Residency

Department of Urology University of Southern California, LAC+USC
2019 Los Angeles CA

Fellowship

Department of Urology Boston Children's Hospital
2022 Boston MA

Media

Caregiver Profile

Meet Dr. Hatim Thaker

Publications

  1. Pediatric bladder tissue engineering: Where have we been and where do we go next? J Pediatr Urol. 2025 Jan 03. View Abstract
  2. Editorial Comment. J Urol. 2024 Nov 21; 101097JU0000000000004327. View Abstract
  3. Clinical and Demographic Factors Linked to Low-Value Emergency Department Visits in Pediatric Patients With Spina Bifida. J Urol. 2024 Nov 12; 101097JU0000000000004329. View Abstract
  4. Epithelial Predominant Wilms Tumor in an Adult Patient: Case Report and Literature Review. J Kidney Cancer VHL. 2024; 11(3):33-39. View Abstract
  5. Human umbilical cord allograft associated with higher pediatric urethrocutaneous fistula repair success rates. J Pediatr Urol. 2024 Aug; 20(4):692.e1-692.e6. View Abstract
  6. Robotic-assisted laparoscopic Malone appendicostomy: a 6-year perspective. Pediatr Surg Int. 2024 Feb 24; 40(1):58. View Abstract
  7. Integrated omics analysis unveils a DNA damage response to neurogenic injury. bioRxiv. 2023 Dec 10. View Abstract
  8. Novel phenotype characterization utilizing electrical impedance myography signatures in murine spinal cord injury neurogenic bladder models. Sci Rep. 2023 11 09; 13(1):19520. View Abstract
  9. Cancer Drug Delivery Systems Using Bacterial Toxin Translocation Mechanisms. Bioengineering (Basel). 2023 Jul 07; 10(7). View Abstract
  10. Laparoscopic vs Sclerotherapy for Varicoceles: Who Prevails? J Urol. 2023 03; 209(3):469-470. View Abstract
  11. Diagnosis and Treatment for Shiga Toxin-Producing Escherichia coli Associated Hemolytic Uremic Syndrome. Toxins (Basel). 2022 12 23; 15(1). View Abstract
  12. Knockin mouse models demonstrate differential contributions of synaptotagmin-1 and -2 as receptors for botulinum neurotoxins. PLoS Pathog. 2021 10; 17(10):e1009994. View Abstract
  13. Onabotulinumtoxin A (Botox): A reasonable alternative for refractory neurogenic bladder dysfunction in children and young adults. Neurourol Urodyn. 2021 11; 40(8):1981-1988. View Abstract
  14. Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection. Nat Commun. 2021 06 18; 12(1):3748. View Abstract
  15. Shiga Toxins: An Update on Host Factors and Biomedical Applications. Toxins (Basel). 2021 03 18; 13(3). View Abstract
  16. Beyond botulinum neurotoxin A for chemodenervation of the bladder. Curr Opin Urol. 2021 03 01; 31(2):140-146. View Abstract
  17. Adjuvant pharmacological and surgical therapy for testicular torsion: Current state of the art. J Pediatr Urol. 2020 Dec; 16(6):807-814. View Abstract
  18. Empirical medical therapy for idiopathic male infertility: A follow-up survey of the American Urological Association. 2020; 1(1):15-20. View Abstract
  19. Empirical medical therapy for idiopathic male infertility. F S Rep. 2020 Jun; 1(1):15-20. View Abstract
  20. Feed and wrap magnetic resonance urography provides anatomic and functional imaging in infants without anesthesia. J Pediatr Urol. 2020 Feb; 16(1):116-120. View Abstract
  21. Multi-Quadrant Hidden Incision Endoscopic Surgery (HIdES) for Pediatric Uretero-Ureterostomy and Distal Ureterectomy. 2019. View Abstract
  22. 'Testosterone Boosting' Supplements Composition and Claims Are not Supported by the Academic Literature. World J Mens Health. 2020 Jan; 38(1):115-122. View Abstract
  23. Extended hospital stay after radical cystectomy with enhanced recovery protocol. Can J Urol. 2019 02; 26(1):9654-9659. View Abstract
  24. A stepwise treatment approach to neonatal genital prolapse. Pediatr Investig. 2018 Mar; 2(1):56-58. View Abstract
  25. Variation in the use of laparoscopy with inguinal hernia repairs in a sample of pediatric patients at children's hospitals. J Pediatr Urol. 2018 04; 14(2):158.e1-158.e7. View Abstract
  26. Open and Robotic Techniques for Appendiceal Interposition in Ureteral Stricture Disease. 2017. View Abstract
  27. The promotion of functional urinary bladder regeneration using anti-inflammatory nanofibers. Biomaterials. 2014 Nov; 35(34):9311-21. View Abstract
  28. Regenerative medicine based applications to combat stress urinary incontinence. World J Stem Cells. 2013 Oct 26; 5(4):112-23. View Abstract
  29. Targeting insulin resistance in type 2 diabetes via immune modulation of cord blood-derived multipotent stem cells (CB-SCs) in stem cell educator therapy: phase I/II clinical trial. BMC Med. 2013 Jul 09; 11:160. View Abstract
  30. Cotransplantation with specific populations of spina bifida bone marrow stem/progenitor cells enhances urinary bladder regeneration. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):4003-8. View Abstract
  31. Engaging stem cells for customized tendon regeneration. Stem Cells Int. 2012; 2012:309187. View Abstract
  32. Urinary bladder smooth muscle regeneration utilizing bone marrow derived mesenchymal stem cell seeded elastomeric poly(1,8-octanediol-co-citrate) based thin films. Biomaterials. 2010 Aug; 31(24):6207-17. View Abstract

Contact Hatim Thaker

Phone: 617-355-7796
Fax: 617-730-0474
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