The intricacy of the neuronal circuitry makes the brain the most complex and fascinating system ever studied by Science. The Kreiman lab is interested in understanding how biological networks encode, process and transmit information. There are two main lines of research in the lab: (i) how circuits of neurons represent visual information and (ii) how gene expression is orchestrated, with a particular emphasis on gene expression in the nervous system. The lab uses a combination of mathematical, computational and experimental tools.
Please visit the Kreiman lab webpage for further information, publications, ongoing projects and job opportunities.
The Kreiman Lab combines high-resolution neurophysiology of the human brain and computational models to understand the processing of visual information--from perception to cognition.
Publications
Theta phase precession supports memory formation and retrieval of naturalistic experience in humans. Nat Hum Behav. 2024 Dec; 8(12):2423-2436. View Abstract
Revealing Vision-Language Integration in the Brain with Multimodal Networks. ArXiv. 2024 Jun 20. View Abstract
The Impact of Scene Context on Visual Object Recognition: Comparing Humans, Monkeys, and Computational Models. bioRxiv. 2024 Jun 01. View Abstract
Neuron-level Prediction and Noise can Implement Flexible Reward-Seeking Behavior. bioRxiv. 2024 May 22. View Abstract
Feature-selective responses in macaque visual cortex follow eye movements during natural vision. Nat Neurosci. 2024 Jun; 27(6):1157-1166. View Abstract
Learning to Learn: How to Continuously Teach Humans and Machines. IEEE Int Conf Comput Vis Workshops. 2023 Oct; 2023:11674-11685. View Abstract
Tuned Compositional Feature Replays for Efficient Stream Learning. IEEE Trans Neural Netw Learn Syst. 2023 Dec 25; PP. View Abstract
Minute-scale periodicity of neuronal firing in the human entorhinal cortex. Cell Rep. 2023 11 28; 42(11):113271. View Abstract
Corrigendum to "What is the intention to move and when does it occur?" [Neurosci. Biobehav. Rev. 151 (2023) 105199]. Neurosci Biobehav Rev. 2023 Sep; 152:105318. View Abstract
What is the intention to move and when does it occur? Neurosci Biobehav Rev. 2023 08; 151:105199. View Abstract
LITTLE MEMORY EDITORS LIVING INSIDE YOUR BRAIN. Front Young Minds. 2023; 11. View Abstract
An adversarial collaboration protocol for testing contrasting predictions of global neuronal workspace and integrated information theory. PLoS One. 2023; 18(2):e0268577. View Abstract
Neural coding: Stimulating cortex to alter visual perception. Curr Biol. 2023 02 06; 33(3):R117-R118. View Abstract
Decoding of human identity by computer vision and neuronal vision. Sci Rep. 2023 01 12; 13(1):651. View Abstract
Cross-task specificity and within-task invariance of cognitive control processes. Cell Rep. 2023 01 31; 42(1):111919. View Abstract
Look twice: A generalist computational model predicts return fixations across tasks and species. PLoS Comput Biol. 2022 11; 18(11):e1010654. View Abstract
Multiple transcription auto regulatory loops can act as robust oscillators and decision-making motifs. Comput Struct Biotechnol J. 2022; 20:5115-5135. View Abstract
Beyond the Cane: Describing Urban Scenes to Blind People for Mobility Tasks. ACM Trans Access Comput. 2022 Sep; 15(3). View Abstract
Face neurons encode nonsemantic features. Proc Natl Acad Sci U S A. 2022 04 19; 119(16):e2118705119. View Abstract
Neurons detect cognitive boundaries to structure episodic memories in humans. Nat Neurosci. 2022 03; 25(3):358-368. View Abstract
When Pigs Fly: Contextual Reasoning in Synthetic and Natural Scenes. IEEE Int Conf Comput Vis Workshops. 2021 Oct; 2021:255-264. View Abstract
Do computational models of vision need shape-based representations? Evidence from an individual with intriguing visual perceptions. Cogn Neuropsychol. 2022 02; 39(1-2):75-77. View Abstract
Visual Search Asymmetry: Deep Nets and Humans Share Similar Inherent Biases. Adv Neural Inf Process Syst. 2021 Dec; 34:6946-6959. View Abstract
Mesoscopic physiological interactions in the human brain reveal small-world properties. Cell Rep. 2021 08 24; 36(8):109585. View Abstract
Beauty is in the eye of the machine. Nat Hum Behav. 2021 06; 5(6):675-676. View Abstract
Incorporating intrinsic suppression in deep neural networks captures dynamics of adaptation in neurophysiology and perception. Sci Adv. 2020 10; 6(42). View Abstract
Can Deep Learning Recognize Subtle Human Activities? Conf Comput Vis Pattern Recognit Workshops. 2020 Jun; 2020. View Abstract
Putting visual object recognition in context. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit. 2020 Jun; 2020:12982-12991. View Abstract
XDream: Finding preferred stimuli for visual neurons using generative networks and gradient-free optimization. PLoS Comput Biol. 2020 06; 16(6):e1007973. View Abstract
A neural network trained for prediction mimics diverse features of biological neurons and perception. Nat Mach Intell. 2020 Apr; 2(4):210-219. View Abstract
Minimal videos: Trade-off between spatial and temporal information in human and machine vision. Cognition. 2020 08; 201:104263. View Abstract
Beyond the feedforward sweep: feedback computations in the visual cortex. Ann N Y Acad Sci. 2020 03; 1464(1):222-241. View Abstract
Neural Interactions Underlying Visuomotor Associations in the Human Brain. Cereb Cortex. 2019 12 17; 29(11):4551-4567. View Abstract
Evolving Images for Visual Neurons Using a Deep Generative Network Reveals Coding Principles and Neuronal Preferences. Cell. 2019 05 02; 177(4):999-1009.e10. View Abstract
It's a small dimensional world after all: Comment on "The unreasonable effectiveness of small neural ensembles in high-dimensional brain" by Alexander N. Gorban et al. Phys Life Rev. 2019 07; 29:96-97. View Abstract
Minimal memory for details in real life events. Sci Rep. 2018 11 12; 8(1):16701. View Abstract
Finding any Waldo with zero-shot invariant and efficient visual search. Nat Commun. 2018 09 13; 9(1):3730. View Abstract
Recurrent computations for visual pattern completion. Proc Natl Acad Sci U S A. 2018 08 28; 115(35):8835-8840. View Abstract
Automating Interictal Spike Detection: Revisiting A Simple Threshold Rule. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:299-302. View Abstract
What is changing when: Decoding visual information in movies from human intracranial recordings. Neuroimage. 2018 10 15; 180(Pt A):147-159. View Abstract
Predicting episodic memory formation for movie events. Sci Rep. 2016 Sep 30; 6:30175. View Abstract
A null model for cortical representations with grandmothers galore. Lang Cogn Neurosci. 2017; 32(3):274-285. View Abstract
Bottom-Up and Top-Down Input Augment the Variability of Cortical Neurons. Neuron. 2016 Aug 03; 91(3):540-547. View Abstract
f-divergence cutoff index to simultaneously identify differential expression in the integrated transcriptome and proteome. Nucleic Acids Res. 2016 06 02; 44(10):e97. View Abstract
Cascade of neural processing orchestrates cognitive control in human frontal cortex. Elife. 2016 Feb 18; 5. View Abstract
There's Waldo! A Normalization Model of Visual Search Predicts Single-Trial Human Fixations in an Object Search Task. Cereb Cortex. 2016 07; 26(7):3064-82. View Abstract
Decrease in gamma-band activity tracks sequence learning. Front Syst Neurosci. 2014; 8:222. View Abstract
Sensitivity to timing and order in human visual cortex. J Neurophysiol. 2015 Mar 01; 113(5):1656-69. View Abstract
Quantitative profiling of peptides from RNAs classified as noncoding. Nat Commun. 2014 Nov 18; 5:5429. View Abstract
Spatiotemporal dynamics underlying object completion in human ventral visual cortex. Neuron. 2014 Aug 06; 83(3):736-48. View Abstract
Corticocortical feedback increases the spatial extent of normalization. Front Syst Neurosci. 2014; 8:105. View Abstract
Short temporal asynchrony disrupts visual object recognition. J Vis. 2014 May 12; 14(5):7. View Abstract
Neural dynamics underlying target detection in the human brain. J Neurosci. 2014 Feb 19; 34(8):3042-55. View Abstract
Theory on the coupled stochastic dynamics of transcription and splice-site recognition. PLoS Comput Biol. 2012; 8(11):e1002747. View Abstract
Temporal stability of visually selective responses in intracranial field potentials recorded from human occipital and temporal lobes. J Neurophysiol. 2012 Dec; 108(11):3073-86. View Abstract
Integrated genome analysis suggests that most conserved non-coding sequences are regulatory factor binding sites. Nucleic Acids Res. 2012 Sep; 40(16):7858-69. View Abstract
Depression-biased reverse plasticity rule is required for stable learning at top-down connections. PLoS Comput Biol. 2012; 8(3):e1002393. View Abstract
Nine criteria for a measure of scientific output. Front Comput Neurosci. 2011; 5:48. View Abstract
Face recognition: vision and emotions beyond the bubble. Curr Biol. 2011 Nov 08; 21(21):R888-90. View Abstract
On the minimization of fluctuations in the response times of autoregulatory gene networks. Biophys J. 2011 Sep 21; 101(6):1297-306. View Abstract
Conservation of transcription factor binding events predicts gene expression across species. Nucleic Acids Res. 2011 Sep 01; 39(16):7092-102. View Abstract
Internally generated preactivation of single neurons in human medial frontal cortex predicts volition. Neuron. 2011 Feb 10; 69(3):548-62. View Abstract
Neuroscience: what we cannot model, we do not understand. Curr Biol. 2011 Feb 08; 21(3):R123-5. View Abstract
Decoding ensemble activity from neurophysiological recordings in the temporal cortex. Annu Int Conf IEEE Eng Med Biol Soc. 2011; 2011:5904-7. View Abstract
How cortical neurons help us see: visual recognition in the human brain. J Clin Invest. 2010 Sep; 120(9):3054-63. View Abstract
Robust selectivity to two-object images in human visual cortex. Curr Biol. 2010 May 11; 20(9):872-9. View Abstract
Widespread transcription at neuronal activity-regulated enhancers. Nature. 2010 May 13; 465(7295):182-7. View Abstract
Measuring sparseness in the brain: comment on Bowers (2009). Psychol Rev. 2010 Jan; 117(1):291-7. View Abstract
Toward unmasking the dynamics of visual perception. Neuron. 2009 Nov 25; 64(4):446-7. View Abstract
From neurons to circuits: linear estimation of local field potentials. J Neurosci. 2009 Nov 04; 29(44):13785-96. View Abstract
Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex. Neuron. 2009 Apr 30; 62(2):281-90. View Abstract
Dynamic population coding of category information in inferior temporal and prefrontal cortex. J Neurophysiol. 2008 Sep; 100(3):1407-19. View Abstract
Single unit approaches to human vision and memory. Curr Opin Neurobiol. 2007 Aug; 17(4):471-5. View Abstract
Differential gene expression between sensory neocortical areas: potential roles for Ten_m3 and Bcl6 in patterning visual and somatosensory pathways. Cereb Cortex. 2008 Jan; 18(1):53-66. View Abstract
A quantitative theory of immediate visual recognition. Prog Brain Res. 2007; 165:33-56. View Abstract
Gene expression changes and molecular pathways mediating activity-dependent plasticity in visual cortex. Nat Neurosci. 2006 May; 9(5):660-8. View Abstract
Object selectivity of local field potentials and spikes in the macaque inferior temporal cortex. Neuron. 2006 Feb 02; 49(3):433-45. View Abstract
Fast readout of object identity from macaque inferior temporal cortex. Science. 2005 Nov 04; 310(5749):863-6. View Abstract
Invariant visual representation by single neurons in the human brain. Nature. 2005 Jun 23; 435(7045):1102-7. View Abstract
Variation in alternative splicing across human tissues. Genome Biol. 2004; 5(10):R74. View Abstract
Identification of sparsely distributed clusters of cis-regulatory elements in sets of co-expressed genes. Nucleic Acids Res. 2004; 32(9):2889-900. View Abstract
A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A. 2004 Apr 20; 101(16):6062-7. View Abstract
Single-neuron correlates of subjective vision in the human medial temporal lobe. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8378-83. View Abstract
Neural correlates of consciousness in humans. Nat Rev Neurosci. 2002 Apr; 3(4):261-70. View Abstract
Stimulus encoding and feature extraction by multiple sensory neurons. J Neurosci. 2002 Mar 15; 22(6):2374-82. View Abstract
Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei. Proc Natl Acad Sci U S A. 2001 Apr 24; 98(9):5270-5. View Abstract
Imagery neurons in the human brain. Nature. 2000 Nov 16; 408(6810):357-61. View Abstract
Category-specific visual responses of single neurons in the human medial temporal lobe. Nat Neurosci. 2000 Sep; 3(9):946-53. View Abstract
Tetanic stimulation leads to increased accumulation of Ca(2+)/calmodulin-dependent protein kinase II via dendritic protein synthesis in hippocampal neurons. J Neurosci. 1999 Sep 15; 19(18):7823-33. View Abstract