Donald Ingber

Publications

1. Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare. ALTEX. 2025 Jan 17. View Abstract
2. Inflammatory Bowel Disease Drivers Revealed in Human Organ Chips. medRxiv. 2024 Dec 08. View Abstract
3. Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation. Elife. 2024 Sep 24; 13. View Abstract
4. Intestinal organ chips for disease modelling and personalized medicine. Nat Rev Gastroenterol Hepatol. 2024 Nov; 21(11):751-773. View Abstract
5. Donepezil Nanoemulsion Induces a Torpor-like State with Reduced Toxicity in Nonhibernating Xenopus laevis Tadpoles. ACS Nano. 2024 Sep 03; 18(35):23991-24003. View Abstract
6. Organ chips with integrated multifunctional sensors enable continuous metabolic monitoring at controlled oxygen levels. Biosens Bioelectron. 2024 Dec 01; 265:116683. View Abstract
7. Exacerbation of influenza virus induced lung injury by alveolar macrophages and its suppression by pyroptosis blockade in a human lung alveolus chip. bioRxiv. 2024 Aug 16. View Abstract
8. Signal amplification by cyclic extension enables high-sensitivity single-cell mass cytometry. Nat Biotechnol. 2024 Jul 29. View Abstract
9. A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation. Angiogenesis. 2024 Nov; 27(4):779-795. View Abstract
10. Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips. Nat Commun. 2024 May 29; 15(1):4578. View Abstract
11. Redox-Modified Nanostructured Electrochemical Surfaces for Continuous Glucose Monitoring in Complex Biological Fluids. Nanomaterials (Basel). 2024 May 03; 14(9). View Abstract
12. MRC1 and LYVE1 expressing macrophages in vascular beds of GNAQ p.R183Q driven capillary malformations in Sturge Weber syndrome. Acta Neuropathol Commun. 2024 Mar 26; 12(1):47. View Abstract
13. Mechanical forces amplify TCR mechanotransduction in T cell activation and function. Appl Phys Rev. 2024 Mar; 11(1):011304. View Abstract
14. Modeling Healthy and Dysbiotic Vaginal Microenvironments in a Human Vagina-on-a-Chip. J Vis Exp. 2024 Feb 16; (204). View Abstract
15. Micrometer-thick and porous nanocomposite coating for electrochemical sensors with exceptional antifouling and electroconducting properties. Nat Commun. 2024 Feb 08; 15(1):711. View Abstract
16. Human organ chips for regenerative pharmacology. Pharmacol Res Perspect. 2024 Feb; 12(1):e01159. View Abstract
17. DNA origami vaccine (DoriVac) nanoparticles improve both humoral and cellular immune responses to infectious diseases. bioRxiv. 2024 Jan 02. View Abstract
18. Direct therapeutic effect of sulfadoxine-pyrimethamine on nutritional deficiency-induced enteric dysfunction in a human Intestine Chip. EBioMedicine. 2024 Jan; 99:104921. View Abstract
19. A human lung alveolus-on-a-chip model of acute radiation-induced lung injury. Nat Commun. 2023 10 16; 14(1):6506. View Abstract
20. Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. J Infect Dis. 2023 10 03; 228(Suppl 5):S337-S354. View Abstract
21. Concerted epithelial and stromal changes during progression of Barrett's Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysis. bioRxiv. 2023 Jun 11. View Abstract
22. Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. PLoS Comput Biol. 2023 05; 19(5):e1011050. View Abstract
23. Epithelial-Stromal Interactions in Barrett's Esophagus Modeled in Human Organ Chips. Gastro Hep Adv. 2023; 2(5):676-680. View Abstract
24. From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics. Biochem J. 2023 02 27; 480(4):243-257. View Abstract
25. Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Commun Med (Lond). 2023 Feb 02; 3(1):16. View Abstract
26. Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Commun Med (Lond). 2023 Jan 12; 3(1):7. View Abstract
27. Rapid quantitation of SARS-CoV-2 antibodies in clinical samples with an electrochemical sensor. Biosens Bioelectron. 2023 Mar 01; 223:115037. View Abstract
28. Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology. Commun Med (Lond). 2022 Dec 06; 2(1):154. View Abstract
29. Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip. Microbiome. 2022 11 26; 10(1):201. View Abstract
30. FcMBL magnetic bead-based MALDI-TOF MS rapidly identifies paediatric blood stream infections from positive blood cultures. PLoS One. 2022; 17(11):e0276777. View Abstract
31. Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors. Nat Commun. 2022 10 12; 13(1):6021. View Abstract
32. Modeling mucus physiology and pathophysiology in human organs-on-chips. Adv Drug Deliv Rev. 2022 12; 191:114542. View Abstract
33. Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity. Mol Ther Nucleic Acids. 2022 Sep 13; 29:923-940. View Abstract
34. PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19. Commun Biol. 2022 08 12; 5(1):808. View Abstract
35. A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma. Nat Biomed Eng. 2022 08; 6(8):968-978. View Abstract
36. Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. medRxiv. 2022 Jul 22. View Abstract
37. Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction. Nat Biomed Eng. 2022 11; 6(11):1236-1247. View Abstract
38. Biofabrication of Multiplexed Electrochemical Immunosensors for Simultaneous Detection of Clinical Biomarkers in Complex Fluids. Adv Healthc Mater. 2022 12; 11(24):e2200589. View Abstract
39. Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches. Adv Sci (Weinh). 2022 09; 9(26):e2200222. View Abstract
40. What Can an Organ-on-a-Chip Teach Us About Human Lung Pathophysiology? Physiology (Bethesda). 2022 09 01; 37(5):0. View Abstract
41. Interdisciplinarity and mechanobiology. iScience. 2022 May 20; 25(5):104187. View Abstract
42. Establishment of physiologically relevant oxygen gradients in microfluidic organ chips. Lab Chip. 2022 04 12; 22(8):1584-1593. View Abstract
43. Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip. Nat Commun. 2022 04 08; 13(1):1928. View Abstract
44. Human organs-on-chips for disease modelling, drug development and personalized medicine. Nat Rev Genet. 2022 08; 23(8):467-491. View Abstract
45. Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ-on-a-Chip. Adv Sci (Weinh). 2022 05; 9(14):e2103241. View Abstract
46. Ultrarapid Method for Coating Electrochemical Sensors with Antifouling Conductive Nanomaterials Enables Highly Sensitive Multiplexed Detection in Whole Blood. Adv Healthc Mater. 2022 04; 11(8):e2102244. View Abstract
47. Establishment of a Modular Anaerobic Human Intestine Chip. Methods Mol Biol. 2022; 2373:69-85. View Abstract
48. Bioinspired design and optimization for thin film wearable and building cooling systems. Bioinspir Biomim. 2021 12 16; 17(1). View Abstract
49. Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine. J Am Assoc Lab Anim Sci. 2022 01 01; 61(1):21-30. View Abstract
50. Self-assembling short immunostimulatory duplex RNAs with broad spectrum antiviral activity. bioRxiv. 2021 Nov 22. View Abstract
51. Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip. J Cyst Fibros. 2022 07; 21(4):606-615. View Abstract
52. Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip. Front Pharmacol. 2021; 12:718484. View Abstract
53. Laboratory-Generated DNA Can Cause Anomalous Pathogen Diagnostic Test Results. Microbiol Spectr. 2021 10 31; 9(2):e0031321. View Abstract
54. Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip. Microbiol Spectr. 2021 10 31; 9(2):e0025721. View Abstract
55. Simulating drug concentrations in PDMS microfluidic organ chips. Lab Chip. 2021 09 14; 21(18):3509-3519. View Abstract
56. Enabling Multiplexed Electrochemical Detection of Biomarkers with High Sensitivity in Complex Biological Samples. Acc Chem Res. 2021 09 21; 54(18):3529-3539. View Abstract
57. Evidence generation and reproducibility in cell and gene therapy research: A call to action. Mol Ther Methods Clin Dev. 2021 Sep 10; 22:11-14. View Abstract
58. Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism. Adv Mater. 2021 Aug; 33(34):e2008161. View Abstract
59. Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock. Nat Biomed Eng. 2022 01; 6(1):8-18. View Abstract
60. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nat Biomed Eng. 2021 08; 5(8):815-829. View Abstract
61. COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature. 2021 07; 595(7865):107-113. View Abstract
62. Transferrin receptor targeting by de novo sheet extension. Proc Natl Acad Sci U S A. 2021 04 27; 118(17). View Abstract
63. Enabling out-of-body experiences for living organs. J Exp Med. 2021 04 05; 218(4). View Abstract
64. Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection. Front Cell Infect Microbiol. 2021; 11:638014. View Abstract
65. A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2. bioRxiv. 2021 Feb 25. View Abstract
66. Anomalous COVID-19 tests hinder researchers. Science. 2021 01 15; 371(6526):244-245. View Abstract
67. Molecular mapping of transmembrane mechanotransduction through the ß1 integrin-CD98hc-TRPV4 axis. J Cell Sci. 2020 11 02; 133(20). View Abstract
68. Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies? Adv Sci (Weinh). 2020 Nov; 7(22):2002030. View Abstract
69. Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients. Nat Commun. 2020 08 26; 11(1):4253. View Abstract
70. Proteomic and Metabolomic Characterization of Human Neurovascular Unit Cells in Response to Methamphetamine. Adv Biosyst. 2020 09; 4(9):e1900230. View Abstract
71. Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations. Sci Adv. 2020 07; 6(30):eabb6049. View Abstract
72. Human Organs-on-Chips for Virology. Trends Microbiol. 2020 11; 28(11):934-946. View Abstract
73. Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. J Am Soc Nephrol. 2020 07; 31(7):1479-1495. View Abstract
74. Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology. Nat Biomed Eng. 2020 Apr; 4(4):477. View Abstract
75. Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development ALTEX. 2020; 37(3):365-394. View Abstract
76. YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Dev Cell. 2020 02 24; 52(4):446-460.e5. View Abstract
77. On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology. Nat Biomed Eng. 2020 04; 4(4):394-406. View Abstract
78. Robotic fluidic coupling and interrogation of multiple vascularized organ chips. Nat Biomed Eng. 2020 04; 4(4):407-420. View Abstract
79. Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips. Nat Biomed Eng. 2020 04; 4(4):421-436. View Abstract
80. Biomimetic smoking robot for in vitro inhalation exposure compatible with microfluidic organ chips. Nat Protoc. 2020 02; 15(2):183-206. View Abstract
81. AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage. APL Bioeng. 2019 Dec; 3(4):046103. View Abstract
82. Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology. Cell Mol Gastroenterol Hepatol. 2020; 9(3):507-526. View Abstract
83. An antifouling coating that enables affinity-based electrochemical biosensing in complex biological fluids. Nat Nanotechnol. 2019 12; 14(12):1143-1149. View Abstract
84. Reproducing human and cross-species drug toxicities using a Liver-Chip. Sci Transl Med. 2019 11 06; 11(517). View Abstract
85. Tumor-Derived Extracellular Vesicles Breach the Intact Blood-Brain Barrier via Transcytosis. ACS Nano. 2019 12 24; 13(12):13853-13865. View Abstract
86. Controllable Fabrication of Inhomogeneous Microcapsules for Triggered Release by Osmotic Pressure. Small. 2019 10; 15(42):e1903087. View Abstract
87. Author Correction: A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip. Nat Biomed Eng. 2019 Jul; 3(7):583. View Abstract
88. Cellular nanoscale stiffness patterns governed by intracellular forces. Nat Mater. 2019 10; 18(10):1071-1077. View Abstract
89. Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies. Nat Commun. 2019 06 13; 10(1):2621. View Abstract
90. A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip. Nat Biomed Eng. 2019 07; 3(7):520-531. View Abstract
91. Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip. iScience. 2019 May 31; 15:391-406. View Abstract
92. Seeing Your Way to New Insights in Biology. J Mol Biol. 2019 06 28; 431(14):2485-2486. View Abstract
93. Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites. Microbiome. 2019 03 20; 7(1):43. View Abstract
94. Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models. Sci Transl Med. 2019 02 13; 11(479). View Abstract
95. Modelling cancer in microfluidic human organs-on-chips. Nat Rev Cancer. 2019 02; 19(2):65-81. View Abstract
96. Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy. Lab Chip. 2019 01 29; 19(3):452-463. View Abstract
97. Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment. F1000Res. 2019; 8:108. View Abstract
98. Rapid Coating Process Generates Omniphobic Dentures in Minutes to Reduce C. albicans Biofouling. ACS Biomater Sci Eng. 2019 Feb 11; 5(2):420-424. View Abstract
99. Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips. J Vis Exp. 2018 10 20; (140). View Abstract
100. From mechanobiology to developmentally inspired engineering. Philos Trans R Soc Lond B Biol Sci. 2018 09 24; 373(1759). View Abstract
101. Collective Shape Actuation of Polymer Double Emulsions by Solvent Evaporation. ACS Appl Mater Interfaces. 2018 Sep 26; 10(38):31865-31869. View Abstract
102. A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. Nat Biotechnol. 2018 10; 36(9):865-874. View Abstract
103. Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip. Nat Protoc. 2018 07; 13(7):1662-1685. View Abstract
104. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Rep. 2018 Jun 19; 23(12):3698. View Abstract
105. Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape. Nano Lett. 2018 06 13; 18(6):3557-3564. View Abstract
106. Developmentally inspired human 'organs on chips'. Development. 2018 05 18; 145(16). View Abstract
107. Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems. Clin Pharmacol Ther. 2018 12; 104(6):1240-1248. View Abstract
108. Microfluidic Organ-on-a-Chip Models of Human Intestine. Cell Mol Gastroenterol Hepatol. 2018; 5(4):659-668. View Abstract
109. Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip. Cell Death Dis. 2018 02 14; 9(2):223. View Abstract
110. Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids. Sci Rep. 2018 02 13; 8(1):2871. View Abstract
111. PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E982-E991. View Abstract
112. Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips. Annu Rev Pharmacol Toxicol. 2018 01 06; 58:37-64. View Abstract
113. Rapid Prototyping of Thermoplastic Microfluidic Devices. Methods Mol Biol. 2018; 1771:161-170. View Abstract
114. Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale. ACS Nano. 2017 12 26; 11(12):12156-12166. View Abstract
115. A Biologically Inspired, Functionally Graded End Effector for Soft Robotics Applications. Soft Robot. 2017 Dec; 4(4):317-323. View Abstract
116. Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. Cell Rep. 2017 Oct 10; 21(2):508-516. View Abstract
117. The Wyss institute: A new model for medical technology innovation and translation across the academic-industrial interface. Bioeng Transl Med. 2017 09; 2(3):247-257. View Abstract
118. Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds. Stem Cell Res. 2017 10; 24:55-60. View Abstract
119. Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clin Pharmacol Ther. 2018 02; 103(2):332-340. View Abstract
120. Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function. Lab Chip. 2017 06 27; 17(13):2264-2271. View Abstract
121. Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities. Lab Chip. 2017 06 27; 17(13):2294-2302. View Abstract
122. An Engineered Human Fc-Mannose-Binding-Lectin Captures Circulating Tumor Cells. Adv Biosyst. 2017 Jul; 1(7):e1700094. View Abstract
123. Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery. Biomaterials. 2017 Sep; 139:187-194. View Abstract
124. Reproductive endocrinology: Cycling through the menstrual cycle - an out-of-body experience. Nat Rev Endocrinol. 2017 07; 13(7):380-382. View Abstract
125. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip. Nat Biomed Eng. 2017; 1. View Abstract
126. New anticoagulant coatings and hemostasis assessment tools to avoid complications with pediatric left ventricular assist devices. J Thorac Cardiovasc Surg. 2017 10; 154(4):1364-1366. View Abstract
127. Theory and associated phenomenology for intrinsic mortality arising from natural selection. PLoS One. 2017; 12(3):e0173677. View Abstract
128. Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro. PLoS One. 2017; 12(2):e0169412. View Abstract
129. Human Lung Small Airway-on-a-Chip Protocol. Methods Mol Biol. 2017; 1612:345-365. View Abstract
130. Direct Bonding of Chitosan Biomaterials to Tissues Using Transglutaminase for Surgical Repair or Device Implantation. Tissue Eng Part A. 2017 02; 23(3-4):135-142. View Abstract
131. Commendation for Exposing Key Advantage of Organ Chip Approach. Cell Syst. 2016 11 23; 3(5):411. View Abstract
132. Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip. Cell Syst. 2016 11 23; 3(5):456-466.e4. View Abstract
133. Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device. J Vis Exp. 2016 Aug 30; (114). View Abstract
134. Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium. Biomed Microdevices. 2016 08; 18(4):73. View Abstract
135. A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood. EBioMedicine. 2016 Jul; 9:217-227. View Abstract
136. Rapid Isolation of Staphylococcus aureus Pathogens from Infected Clinical Samples Using Magnetic Beads Coated with Fc-Mannose Binding Lectin. PLoS One. 2016; 11(6):e0156287. View Abstract
137. Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip. Tissue Eng Part C Methods. 2016 05; 22(5):509-15. View Abstract
138. Reverse Engineering Human Pathophysiology with Organs-on-Chips. Cell. 2016 Mar 10; 164(6):1105-1109. View Abstract
139. Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip. PLoS One. 2016; 11(3):e0150360. View Abstract
140. Purified and Recombinant Hemopexin: Protease Activity and Effect on Neutrophil Chemotaxis. Mol Med. 2016 Sep; 22:22-31. View Abstract
141. A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function. Nat Commun. 2016 Jan 06; 7:10176. View Abstract
142. Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. Am J Respir Cell Mol Biol. 2016 Jan; 54(1):103-13. View Abstract
143. Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro. Nat Methods. 2016 Feb; 13(2):151-7. View Abstract
144. Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip. Proc Natl Acad Sci U S A. 2016 Jan 05; 113(1):E7-15. View Abstract
145. Shear-Activated Nanoparticle Aggregates Combined With Temporary Endovascular Bypass to Treat Large Vessel Occlusion. Stroke. 2015 Dec; 46(12):3507-13. View Abstract
146. Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles. Small. 2015 Nov 11; 11(42):5657-66. View Abstract
147. Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation. Nat Mater. 2015 Dec; 14(12):1269-77. View Abstract
148. Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption. Biomaterials. 2015 Oct; 67:382-92. View Abstract
149. Control of cancer formation by intrinsic genetic noise and microenvironmental cues. Nat Rev Cancer. 2015 Aug; 15(8):499-509. View Abstract
150. Programed Death is Favored by Natural Selection in Spatial Systems. Phys Rev Lett. 2015 Jun 12; 114(23):238103. View Abstract
151. Mesenchymal condensation-dependent accumulation of collagen VI stabilizes organ-specific cell fates during embryonic tooth formation. Dev Dyn. 2015 Jun; 244(6):713-23. View Abstract
152. Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis. J Exp Med. 2015 May 04; 212(5):665-80. View Abstract
153. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene. 2016 Jan 21; 35(3):314-22. View Abstract
154. Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems. Lab Chip. 2015 Feb 07; 15(3):745-52. View Abstract
155. Generation of biocompatible droplets for in vivo and in vitro measurement of cell-generated mechanical stresses. Methods Cell Biol. 2015; 125:373-90. View Abstract
156. Targeted drug delivery to flow-obstructed blood vessels using mechanically activated nanotherapeutics. JAMA Neurol. 2015 Jan; 72(1):119-22. View Abstract
157. Engineered in vitro disease models. Annu Rev Pathol. 2015; 10:195-262. View Abstract
158. A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling. Nat Biotechnol. 2014 Nov; 32(11):1134-40. View Abstract
159. An extracorporeal blood-cleansing device for sepsis therapy. Nat Med. 2014 Oct; 20(10):1211-6. View Abstract
160. Mononuclear cells from dedifferentiation of mouse myotubes display remarkable regenerative capability. Stem Cells. 2014 Sep; 32(9):2492-501. View Abstract
161. Microfluidic organs-on-chips. Nat Biotechnol. 2014 Aug; 32(8):760-72. View Abstract
162. Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis. Proc Natl Acad Sci U S A. 2014 Aug 05; 111(31):11293-8. View Abstract
163. Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. Adv Drug Deliv Rev. 2014 Dec 15; 79-80:107-18. View Abstract
164. Bone marrow-on-a-chip replicates hematopoietic niche physiology in vitro. Nat Methods. 2014 Jun; 11(6):663-9. View Abstract
165. Interview with Donald E Ingber. Nanomedicine (Lond). 2014 May; 9(7):949-54. View Abstract
166. Tensegrity, cellular biophysics, and the mechanics of living systems. Rep Prog Phys. 2014 Apr; 77(4):046603. View Abstract
167. Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation. Adv Mater. 2014 May 28; 26(20):3253-7. View Abstract
168. Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. J Cell Sci. 2014 Apr 15; 127(Pt 8):1672-83. View Abstract
169. Mechanotransduction of fluid stresses governs 3D cell migration. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2447-52. View Abstract
170. A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells. Sci Rep. 2014 Jan 29; 4:3896. View Abstract
171. A microdevice for rapid optical detection of magnetically captured rare blood pathogens. Lab Chip. 2014 Jan 07; 14(1):182-8. View Abstract
172. Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Sci Transl Med. 2014 Jan 01; 6(217):217ra2. View Abstract
173. Developing microphysiological systems for use as regulatory tools--challenges and opportunities. ALTEX. 2014; 31(3):364-7. View Abstract
174. Quantifying cell-generated mechanical forces within living embryonic tissues. Nat Methods. 2014 Feb; 11(2):183-9. View Abstract
175. Reply: To PMID 23711562. Neonatology. 2014; 105(1):26. View Abstract
176. Microfabrication of human organs-on-chips. Nat Protoc. 2013 Nov; 8(11):2135-57. View Abstract
177. Clear castable polyurethane elastomer for fabrication of microfluidic devices. Lab Chip. 2013 Oct 07; 13(19):3956-64. View Abstract
178. Intraductal injection for localized drug delivery to the mouse mammary gland. J Vis Exp. 2013 Oct 04; (80). View Abstract
179. How changes in extracellular matrix mechanics and gene expression variability might combine to drive cancer progression. PLoS One. 2013; 8(10):e76122. View Abstract
180. Organs on Chips 2013. Lab Chip. 2013 Sep 21; 13(18):3447-8. View Abstract
181. Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. Integr Biol (Camb). 2013 Sep; 5(9):1130-40. View Abstract
182. Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. Integr Biol (Camb). 2013 Sep; 5(9):1119-29. View Abstract
183. Platform for high-throughput testing of the effect of soluble compounds on 3D cell cultures. Anal Chem. 2013 Sep 03; 85(17):8085-94. View Abstract
184. Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan. Integr Biol (Camb). 2013 Aug; 5(8):1045-56. View Abstract
185. Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13528-33. View Abstract
186. SLLISWD sequence in the 10FNIII domain initiates fibronectin fibrillogenesis. J Biol Chem. 2013 Jul 19; 288(29):21329-21340. View Abstract
187. Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurity. Neonatology. 2013; 104(1):56-64. View Abstract
188. Nogo-A is a negative regulator of CNS angiogenesis. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):E1943-52. View Abstract
189. Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics. Nat Commun. 2013; 4:1759. View Abstract
190. Mechanobiology and developmental control. Annu Rev Cell Dev Biol. 2013; 29:27-61. View Abstract
191. A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice. Sci Transl Med. 2012 Nov 07; 4(159):159ra147. View Abstract
192. A mini-microscope for in situ monitoring of cells. Lab Chip. 2012 Oct 21; 12(20):3976-82. View Abstract
193. Paxillin controls directional cell motility in response to physical cues. Cell Adh Migr. 2012 Nov-Dec; 6(6):502-8. View Abstract
194. LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. PLoS One. 2012; 7(7):e41596. View Abstract
195. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science. 2012 Aug 10; 337(6095):738-42. View Abstract
196. Mechanosensitive mechanisms in transcriptional regulation. J Cell Sci. 2012 Jul 01; 125(Pt 13):3061-73. View Abstract
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