Education

Undergraduate School

Engineering Sciences Dartmouth College
1993 Hanover NH

Graduate School

PhD, Biomedical Engineering Duke University
2001 Durham NC

Medical School

Duke University
2001 Durham NC

Internship

Pediatrics University of California at San Francisco
2002 San Francisco CA

Residency

Pediatrics University of California at San Francisco
2004 San Francisco CA

Fellowship

Cardiology Boston Children's Hospital
2007 Boston MA

Fellowship

Senior Fellow, Cardiac Imaging Boston Children's Hospital
2007 Boston MA

Publications

  1. Automated Echocardiographic Detection of Congenital Heart Disease Using Artificial Intelligence. medRxiv. 2026 Jan 26. View Abstract
  2. Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study. Circ Cardiovasc Interv. 2025 Sep; 18(9):e015002. View Abstract
  3. Longitudinal Changes in Myocardial Deformation in Hutchinson-Gilford Progeria Syndrome. Circ Cardiovasc Imaging. 2025 Feb; 18(2):e017544. View Abstract
  4. Systemically injected oxygen within rapidly dissolving microbubbles improves the outcomes of severe hypoxaemia in swine. Nat Biomed Eng. 2024 11; 8(11):1396-1411. View Abstract
  5. Identifying high-risk Fontan phenotypes using K-means clustering of cardiac magnetic resonance-based dyssynchrony metrics. J Cardiovasc Magn Reson. 2024; 26(2):101060. View Abstract
  6. Evolving Role of Three-Dimensional Echocardiography for Right Ventricular Volume Analysis in Pediatric Heart Disease: Literature Review and Clinical Applications. J Am Soc Echocardiogr. 2024 Jun; 37(6):634-640. View Abstract
  7. Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome. J Am Heart Assoc. 2024 Feb 06; 13(3):e031470. View Abstract
  8. Euclidean and Shape-Based Analysis of the Dynamic Mitral Annulus in Children using a Novel Open-Source Framework. J Am Soc Echocardiogr. 2024 Feb; 37(2):259-267. View Abstract
  9. Ventricular dyssynchrony late after the Fontan operation is associated with decreased survival. J Cardiovasc Magn Reson. 2023 11 20; 25(1):66. View Abstract
  10. Right Heart Remodeling After Pulmonary Valve Replacement in Patients With Pulmonary Atresia or Critical Stenosis With Intact Ventricular Septum. J Am Heart Assoc. 2023 11 07; 12(21):e031090. View Abstract
  11. Ebstein Anomaly: More Than Just a Tricuspid Valve Issue. J Am Coll Cardiol. 2023 08 08; 82(6):514-516. View Abstract
  12. Right ventricular contraction patterns in healthy children using three-dimensional echocardiography. Front Cardiovasc Med. 2023; 10:1141027. View Abstract
  13. Transcatheter Ductus Arteriosus Stenting for Acute Pediatric Pulmonary Arterial Hypertension is Associated with Improved Right Ventricular Echocardiography Strain. Pediatr Cardiol. 2024 Oct; 45(7):1573-1580. View Abstract
  14. A comparison between the apical and subcostal view for three-dimensional echocardiographic assessment of right ventricular volumes in pediatric patients. Front Cardiovasc Med. 2023; 10:1137814. View Abstract
  15. Pediatric Normal Values and Z Score Equations for Left and Right Ventricular Strain by Two-Dimensional Speckle-Tracking Echocardiography Derived from a Large Cohort of Healthy Children. J Am Soc Echocardiogr. 2023 03; 36(3):310-323. View Abstract
  16. Impact of Udenafil on Echocardiographic Indices of Single Ventricle Size and Function in FUEL Study Participants. Circ Cardiovasc Imaging. 2022 11; 15(11):e013676. View Abstract
  17. Visualization and Quantification of the Unrepaired Complete Atrioventricular Canal Valve Using Open-Source Software. J Am Soc Echocardiogr. 2022 09; 35(9):985-996.e11. View Abstract
  18. Three-Dimensional Echocardiography Right Ventricular Volumes and Ejection Fraction Reference Values in Children: A North American Multicentre Study. Can J Cardiol. 2022 09; 38(9):1426-1433. View Abstract
  19. Variability in Longitudinal Early Diastolic Strain Rate in Children: Authors' Reply. J Am Soc Echocardiogr. 2022 07; 35(7):786-788. View Abstract
  20. Characterization of Circulating and Urinary Biomarkers in the Fontan Circulation and Their Correlation With Cardiac Imaging. Am J Cardiol. 2022 01 01; 162:177-183. View Abstract
  21. Normal Left Ventricular Systolic and Diastolic Strain Rate Values in Children Derived from Two-Dimensional Speckle-Tracking Echocardiography. J Am Soc Echocardiogr. 2021 12; 34(12):1303-1315.e3. View Abstract
  22. A multicenter study of three-dimensional echocardiographic evaluation of normal pediatric left ventricular volumes and function. Echocardiography. 2021 04; 38(4):641-645. View Abstract
  23. Detailed Assessment of Left Ventricular Function in Multisystem Inflammatory Syndrome in Children, Using Strain Analysis. CJC Open. 2021 Jul; 3(7):880-887. View Abstract
  24. Risk Factors for Left Ventricular Dysfunction Following Surgical Management of Cardiac Fibroma. Circ Cardiovasc Imaging. 2021 02; 14(2):e011748. View Abstract
  25. Dynamic Annular Modeling of the Unrepaired Complete Atrioventricular Canal Annulus. Ann Thorac Surg. 2022 02; 113(2):654-662. View Abstract
  26. Autologous mitochondrial transplantation for cardiogenic shock in pediatric patients following ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2021 Sep; 162(3):992-1001. View Abstract
  27. Cardiac Dysfunction in Multisystem Inflammatory Syndrome in Children: A Call to Action. J Am Coll Cardiol. 2020 10 27; 76(17):1962-1964. View Abstract
  28. Cardiac resynchronization therapy improves the ventricular function of patients with Fontan physiology. Am Heart J. 2020 12; 230:82-92. View Abstract
  29. Impact of Pregnancy on Ventricular Strain in Women with Repaired Tetralogy of Fallot. Pediatr Cardiol. 2020 Dec; 41(8):1795-1799. View Abstract
  30. Resynchronizing Right and Left Ventricles With Right Bundle Branch Block in the Congenital Heart Disease Population. JACC Clin Electrophysiol. 2020 12; 6(14):1762-1772. View Abstract
  31. Speckle tracking echocardiographically-based analysis of ventricular strain in children: an intervendor comparison. Cardiovasc Ultrasound. 2020 May 21; 18(1):15. View Abstract
  32. Three-Dimensional Speckle Tracking Echocardiography for Assessment of Left Ventricular Function and Myocardial Mechanics after Pediatric Heart Transplantation. J Heart Lung Transplant. 2020 Apr; 39(4S):S457. View Abstract
  33. Three-Dimensional Modeling of Surgically Implanted Stent-Based Valves in the Mitral Position in Children. Ann Thorac Surg. 2020 08; 110(2):670-675. View Abstract
  34. Normal Values for Left Ventricular Strain and Synchrony in Children Based on Speckle Tracking Echocardiography. Am J Cardiol. 2019 05 01; 123(9):1546-1554. View Abstract
  35. Characterization of Left Ventricular Dysfunction by Myocardial Strain in Critical Pulmonary Stenosis and Pulmonary Atresia After Neonatal Pulmonary Valve Balloon Dilation. Am J Cardiol. 2019 02 01; 123(3):454-459. View Abstract
  36. Three-Dimensional Mitral Valve Morphology in Children and Young Adults With Marfan Syndrome. J Am Soc Echocardiogr. 2018 11; 31(11):1168-1177.e1. View Abstract
  37. Left Atrial Size and Function in Patients With Congenital Aortic Valve Stenosis. Am J Cardiol. 2018 11 01; 122(9):1541-1545. View Abstract
  38. Impact of Ventricular Morphology on Fiber Stress and Strain in Fontan Patients. Circ Cardiovasc Imaging. 2018 07; 11(7):e006738. View Abstract
  39. Impact of surgical pulmonary valve replacement on ventricular strain and synchrony in patients with repaired tetralogy of Fallot: a cardiovascular magnetic resonance feature tracking study. J Cardiovasc Magn Reson. 2018 06 18; 20(1):37. View Abstract
  40. Impact of the cone operation on left ventricular size, function, and dyssynchrony in Ebstein anomaly: a cardiovascular magnetic resonance study. J Cardiovasc Magn Reson. 2018 05 21; 20(1):32. View Abstract
  41. Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. Am J Cardiol. 2018 07 15; 122(2):331-339. View Abstract
  42. Left Atrial Volumes and Strain in Healthy Children Measured by Three-Dimensional Echocardiography: Normal Values and Maturational Changes. J Am Soc Echocardiogr. 2018 02; 31(2):187-193.e1. View Abstract
  43. Three-Dimensional Mitral Valve Morphology and Age-Related Trends in Children and Young Adults with Structurally Normal Hearts Using Transthoracic Echocardiography. J Am Soc Echocardiogr. 2017 Jun; 30(6):561-571. View Abstract
  44. Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury. J Thorac Cardiovasc Surg. 2017 07; 154(1):286-289. View Abstract
  45. Fetal Growth Restriction and Long-Term Cardiovascular Risk: Is It Time to Get With the Program? Circ Cardiovasc Imaging. 2017 01; 10(1). View Abstract
  46. Echocardiography and magnetic resonance imaging based strain analysis of functional single ventricles: a study of intra- and inter-modality reproducibility. Int J Cardiovasc Imaging. 2016 Jul; 32(7):1113-20. View Abstract
  47. Comparison Between Echocardiography and Cardiac Magnetic Resonance Imaging in Predicting Transplant-Free Survival After the Fontan Operation. Am J Cardiol. 2015 Oct 01; 116(7):1132-8. View Abstract
  48. Relation of biventricular strain and dyssynchrony in repaired tetralogy of fallot measured by cardiac magnetic resonance to death and sustained ventricular tachycardia. Am J Cardiol. 2015 Mar 01; 115(5):676-80. View Abstract
  49. Impact of transcatheter pulmonary valve replacement on biventricular strain and synchrony assessed by cardiac magnetic resonance feature tracking. Circ Cardiovasc Interv. 2013 Dec; 6(6):680-7. View Abstract
  50. Ventricular strain in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome before and after prenatal aortic valvuloplasty. Fetal Diagn Ther. 2014; 35(1):18-26. View Abstract
  51. Left ventricular function and geometry in fetuses with severe tricuspid regurgitation. Ultrasound Obstet Gynecol. 2012 Jul; 40(1):55-61. View Abstract
  52. Comparison of cardiac MRI tissue tracking and myocardial tagging for assessment of regional ventricular strain. Int J Cardiovasc Imaging. 2012 Dec; 28(8):2009-18. View Abstract
  53. Circumferential and longitudinal ventricular strain in the normal human fetus. J Am Soc Echocardiogr. 2012 Jan; 25(1):105-11. View Abstract
  54. Postnatal left ventricular diastolic function after fetal aortic valvuloplasty. Am J Cardiol. 2011 Aug 15; 108(4):556-60. View Abstract
  55. Longitudinal exercise capacity of patients with repaired tetralogy of fallot. Am J Cardiol. 2011 Jul 01; 108(1):99-105. View Abstract
  56. Relation of left ventricular dyssynchrony measured by cardiac magnetic resonance tissue tracking in repaired tetralogy of fallot to ventricular tachycardia and death. Am J Cardiol. 2011 May 15; 107(10):1535-40. View Abstract
  57. Late pulmonary valve replacement in patients with pulmonary atresia and intact ventricular septum: a case-matched study. Ann Thorac Surg. 2011 Feb; 91(2):555-60. View Abstract
  58. Long-term pulmonary regurgitation following balloon valvuloplasty for pulmonary stenosis risk factors and relationship to exercise capacity and ventricular volume and function. J Am Coll Cardiol. 2010 Mar 09; 55(10):1041-7. View Abstract
  59. Pulmonary valve replacement in tetralogy of Fallot: impact on survival and ventricular tachycardia. Circulation. 2009 Jan 27; 119(3):445-51. View Abstract
  60. A computer model of normal conduction in the human atria. Circ Res. 2000 Sep 29; 87(7):E25-36. View Abstract
  61. A flexible method for simulating cardiac conduction in three-dimensional complex geometries. J Electrocardiol. 2000 Jul; 33(3):241-51. View Abstract
  62. A finite volume model of cardiac propagation. Ann Biomed Eng. 1997 Mar-Apr; 25(2):315-34. View Abstract

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