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Related Research Units

Research Overview

Our laboratory focuses on two types of early insults to the developing nervous system-- chemical exposures (e.g., lead, elemental mercury, methylmercury, arsenic, manganese, pesticides and anesthetic agents) and insults related to serious medical conditions (e.g., congenital heart lesions, schistosomiasis and congenital diaphragmatic hernia). 

The specific aims of the chemical exposure studies are to: Develop new strategies for quantifying exposure. Define the "behavioral signature," if any, associated with different exposures and exposure scenarios. Identify factors that either increase or decrease an individual's risk associated with exposure to a chemical. The goal of the studies on endogenous insults related to medical conditions is to characterize the associated behavioral risks, particularly risks associated with drug therapies or with invasive interventions, such as procedures to repair serious congenital heart disease. 

Research Background

David Bellinger has a PhD in Psychology from Cornell University and a Master's degree in Epidemiology from the Harvard School of Public Health. He holds a secondary appointment as Professor in the Department of Environmental Health at the Harvard School of Public Health. He is currently President of the International Society for Children's Health and the Environment.

Publications

  1. Evaluating the factor structure of the Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) in adults with congenital heart disease. Clin Neuropsychol. 2024 Dec 31; 1-12. View Abstract
  2. Quantifying the association between PM2.5 air pollution and IQ loss in children: a systematic review and meta-analysis. Environ Health. 2024 Nov 18; 23(1):101. View Abstract
  3. Family Socioeconomic Status and Neurodevelopment Among Patients With Dextro-Transposition of the Great Arteries. JAMA Netw Open. 2024 Nov 04; 7(11):e2445863. View Abstract
  4. Lead Poisoning. N Engl J Med. 2024 Oct 31; 391(17):1621-1631. View Abstract
  5. Associations of maternal and paternal preconception and maternal pregnancy urinary phthalate biomarker and bisphenol A concentrations with offspring autistic behaviors: The PEACE study. Environ Res. 2024 Dec 15; 263(Pt 3):120253. View Abstract
  6. Pre-natal and early life lead exposure and childhood inhibitory control: an item response theory approach to improve measurement precision of inhibitory control. Environ Health. 2024 Sep 05; 23(1):71. View Abstract
  7. Meta-regression of sulcal patterns, clinical and environmental factors on neurodevelopmental outcomes in participants with multiple CHD types. Cereb Cortex. 2024 06 04; 34(6). View Abstract
  8. Sensitive development windows of prenatal air pollution and cognitive functioning in preschool age Mexican children. Environ Epidemiol. 2024 Feb; 8(1):e291. View Abstract
  9. Paternal and maternal preconception and maternal pregnancy urinary concentrations of parabens in relation to child behavior. Andrology. 2025 Jan; 13(1):22-33. View Abstract
  10. Cross-sectional and prospective associations of early childhood circulating metals with early and mid-childhood cognition in the Project Viva cohort. Environ Res. 2024 Apr 01; 246:118068. View Abstract
  11. Paternal and maternal preconception and maternal pregnancy urinary phthalate metabolite and BPA concentrations in relation to child behavior. Environ Int. 2024 Jan; 183:108337. View Abstract
  12. Design and Harmonization Approach for the Multi-Institutional Neurocognitive Discovery Study (MINDS) of Adult Congenital Heart Disease (ACHD) Neuroimaging Ancillary Study: A Technical Note. J Cardiovasc Dev Dis. 2023 Sep 06; 10(9). View Abstract
  13. Mixtures of Metals and Micronutrients in Early Pregnancy and Cognition in Early and Mid-Childhood: Findings from the Project Viva Cohort. Environ Health Perspect. 2023 08; 131(8):87008. View Abstract
  14. Prenatal ambient air pollutant mixture exposure and neurodevelopment in urban children in the Northeastern United States. Environ Res. 2023 09 15; 233:116394. View Abstract
  15. Lithium in Drinking Water-A Novel Environmental Risk Factor for Autism Spectrum Disorder? JAMA Pediatr. 2023 06 01; 177(6):563-564. View Abstract
  16. In utero arsenic exposure and early childhood motor development in the New Hampshire Birth Cohort Study. Front Epidemiol. 2023; 3:1139337. View Abstract
  17. Single Ventricle Reconstruction III: Brain Connectome and Neurodevelopmental Outcomes: Design, Recruitment, and Technical Challenges of a Multicenter, Observational Neuroimaging Study. Diagnostics (Basel). 2023 Apr 30; 13(9). View Abstract
  18. Who benefits most from a prenatal HEPA filter air cleaner intervention on childhood cognitive development? The UGAAR randomized controlled trial. Environ Res. 2023 Aug 15; 231(Pt 1):115991. View Abstract
  19. Single Ventricle Reconstruction III: Brain Connectome and Neurodevelopmental Outcomes: Design, Recruitment, and Technical Challenges of a Multicenter, Observational Neuroimaging Study. medRxiv. 2023 Apr 17. View Abstract
  20. Social cognition and behavioral outcomes in congenital heart disease: profiles and neuropsychiatric comorbidities. Child Neuropsychol. 2023 11; 29(7):1041-1063. View Abstract
  21. Associations of Perinatal Metal and Metalloid Exposures with Early Child Behavioral Development Over Time in the New Hampshire Birth Cohort Study. Expo Health. 2024 Feb; 16(1):135-148. View Abstract
  22. Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease. JAMA Netw Open. 2023 01 03; 6(1):e2253191. View Abstract
  23. Childhood exposures to environmental chemicals and neurodevelopmental outcomes in congenital heart disease. PLoS One. 2022; 17(11):e0277611. View Abstract
  24. Exposure to metal mixtures and neuropsychological functioning in middle childhood. Neurotoxicology. 2022 12; 93:84-91. View Abstract
  25. The pediatric heart network's study on long-term outcomes of children with HLHS and the impact of Norwood Shunt type in the single ventricle reconstruction trial cohort (SVRIII): Design and adaptations. Am Heart J. 2022 Dec; 254:216-227. View Abstract
  26. Sleep Patterns in Young Children with Congenital Heart Disease. J Pediatr. 2023 01; 252:198-203.e2. View Abstract
  27. The association of prenatal manganese exposure with problem-solving skills and its mediation by the building blocks of executive function. Neurotoxicology. 2022 09; 92:191-199. View Abstract
  28. Portable HEPA filter air cleaner use during pregnancy and children's autistic behaviors at four years of age: The UGAAR randomized controlled trial. Environ Int. 2022 10; 168:107432. View Abstract
  29. A replicable strategy for mapping air pollution's community-level health impacts and catalyzing prevention. Environ Health. 2022 07 18; 21(1):70. View Abstract
  30. Long-term cognitive and behavioral outcomes following early exposure to general anesthetics. Curr Opin Anaesthesiol. 2022 Aug 01; 35(4):442-447. View Abstract
  31. Portable HEPA Filter Air Cleaner Use during Pregnancy and Children's Cognitive Performance at Four Years of Age: The UGAAR Randomized Controlled Trial. Environ Health Perspect. 2022 06; 130(6):67006. View Abstract
  32. Machine Learning to Predict Executive Function in Adolescents with Repaired d-Transposition of the Great Arteries, Tetralogy of Fallot, and Fontan Palliation. J Pediatr. 2022 07; 246:145-153. View Abstract
  33. Anesthesia and Developing Brains: Unanswered Questions and Proposed Paths Forward. Anesthesiology. 2022 03 01; 136(3):500-512. View Abstract
  34. Prenatal exposure to a mixture of organochlorines and metals and internalizing symptoms in childhood and adolescence. Environ Res. 2022 05 15; 208:112701. View Abstract
  35. Bayesian kernel machine regression-causal mediation analysis. Stat Med. 2022 02 28; 41(5):860-876. View Abstract
  36. Prenatal Exposure to Chemical Mixtures and Cognitive Flexibility among Adolescents. Toxics. 2021 Dec 02; 9(12). View Abstract
  37. It's Time to End Lead Poisoning in the United States. JAMA Pediatr. 2021 12 01; 175(12):1216-1217. View Abstract
  38. Prenatal exposure to chemical mixtures and working memory among adolescents. Environ Res. 2022 04 01; 205:112436. View Abstract
  39. Prenatal Exposure to Chemical Mixtures and Inhibition among Adolescents. Toxics. 2021 Nov 16; 9(11). View Abstract
  40. Sex-specific relationships of the infant microbiome and early-childhood behavioral outcomes. Pediatr Res. 2022 08; 92(2):580-591. View Abstract
  41. Air pollution and development in Africa: impacts on health, the economy, and human capital. Lancet Planet Health. 2021 10; 5(10):e681-e688. View Abstract
  42. A Cross-validated Ensemble Approach to Robust Hypothesis Testing of Continuous Nonlinear Interactions: Application to Nutrition-Environment Studies. J Am Stat Assoc. 2022; 117(538):561-573. View Abstract
  43. Critical windows of susceptibility in the association between manganese and neurocognition in Italian adolescents living near ferro-manganese industry. Neurotoxicology. 2021 12; 87:51-61. View Abstract
  44. Abnormal Right-Hemispheric Sulcal Patterns Correlate with Executive Function in Adolescents with Tetralogy of Fallot. Cereb Cortex. 2021 08 26; 31(10):4670-4680. View Abstract
  45. Prenatal PM2.5 exposure in the second and third trimesters predicts neurocognitive performance at age 9-10 years: A cohort study of Mexico City children. Environ Res. 2021 11; 202:111651. View Abstract
  46. Prenatal and childhood exposure to per- and polyfluoroalkyl substances (PFAS) and child executive function and behavioral problems. Environ Res. 2021 11; 202:111621. View Abstract
  47. Portable HEPA filter air cleaner use during pregnancy and children's behavior problem scores: a secondary analysis of the UGAAR randomized controlled trial. Environ Health. 2021 07 05; 20(1):78. View Abstract
  48. Prenatal exposure to a mixture of elements and neurobehavioral outcomes in mid-childhood: Results from Project Viva. Environ Res. 2021 10; 201:111540. View Abstract
  49. Executive functions in children with heart disease: a systematic review and meta-analysis. Cardiol Young. 2021 Dec; 31(12):1914-1922. View Abstract
  50. Performance on the ROCF at 8 Years Predicts Academic Achievement at 16 Years in Individuals with Dextro-Transposition of the Great Arteries. J Int Neuropsychol Soc. 2021 10; 27(9):857-864. View Abstract
  51. The origins and development of the Cardiac Neurodevelopmental Outcome Collaborative: creating innovative clinical, quality improvement, and research opportunities - Corrigendum. Cardiol Young. 2021 01; 31(1):175. View Abstract
  52. Stunting and lead: using causal mediation analysis to better understand how environmental lead exposure affects cognitive outcomes in children. J Neurodev Disord. 2020 12 16; 12(1):39. View Abstract
  53. Neurodevelopmental evaluation for school-age children with congenital heart disease: recommendations from the cardiac neurodevelopmental outcome collaborative. Cardiol Young. 2020 Nov; 30(11):1623-1636. View Abstract
  54. The origins and development of the cardiac neurodevelopment outcome collaborative: creating innovative clinical, quality improvement, and research opportunities. Cardiol Young. 2020 Nov; 30(11):1597-1602. View Abstract
  55. Antenatal Depressive Symptoms and Neurodevelopment Outcomes in Children at 30 Months. A Study From South India. Front Psychiatry. 2020; 11:486175. View Abstract
  56. Prenatal PM2.5 exposure and behavioral development in children from Mexico City. Neurotoxicology. 2020 12; 81:109-115. View Abstract
  57. Associations of a Metal Mixture Measured in Multiple Biomarkers with IQ: Evidence from Italian Adolescents Living near Ferroalloy Industry. Environ Health Perspect. 2020 09; 128(9):97002. View Abstract
  58. Neurocognitive and psychosocial outcomes in adult congenital heart disease: a lifespan approach. Heart. 2021 01; 107(2):159-167. View Abstract
  59. Randomized Controlled Trial of Working Memory Intervention in Congenital Heart Disease. J Pediatr. 2020 12; 227:191-198.e3. View Abstract
  60. Association of Exposure to Endocrine-Disrupting Chemicals During Adolescence With Attention-Deficit/Hyperactivity Disorder-Related Behaviors. JAMA Netw Open. 2020 08 03; 3(8):e2015041. View Abstract
  61. Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease. Cereb Cortex. 2020 03 21; 30(2):476-487. View Abstract
  62. Parental preconception and prenatal urinary bisphenol A and paraben concentrations and child behavior. Environ Epidemiol. 2020 Feb; 4(1):e082. View Abstract
  63. Modification of the effects of prenatal manganese exposure on child neurodevelopment by maternal anemia and iron deficiency. Pediatr Res. 2020 08; 88(2):325-333. View Abstract
  64. The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants. Eur J Cardiothorac Surg. 2020 01 01; 57(1):63-71. View Abstract
  65. Using the delayed spatial alternation task to assess environmentally associated changes in working memory in very young children. Neurotoxicology. 2020 03; 77:71-79. View Abstract
  66. In utero exposure to mercury and childhood overweight or obesity: counteracting effect of maternal folate status. BMC Med. 2019 11 28; 17(1):216. View Abstract
  67. Time-varying associations between prenatal metal mixtures and rapid visual processing in children. Environ Health. 2019 10 30; 18(1):92. View Abstract
  68. Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors. Environ Health Perspect. 2019 10; 127(10):105001. View Abstract
  69. Behavior and Quality of Life at 6 Years for Children With Hypoplastic Left Heart Syndrome. Pediatrics. 2019 11; 144(5). View Abstract
  70. Autism and Congenital Heart Disease: Evidence and Unresolved Questions. Pediatrics. 2019 11; 144(5). View Abstract
  71. Early life risk factors of motor, cognitive and language development: a pooled analysis of studies from low/middle-income countries. BMJ Open. 2019 10 03; 9(10):e026449. View Abstract
  72. Is Fluoride Potentially Neurotoxic? JAMA Pediatr. 2019 Oct 01; 173(10):915-917. View Abstract
  73. Erratum: "Low-Level Environmental Lead Exposure and Children's Intellectual Function: An International Pooled Analysis". Environ Health Perspect. 2019 Sep; 127(9):99001. View Abstract
  74. Prenatal lead exposure and childhood executive function and behavioral difficulties in project viva. Neurotoxicology. 2019 12; 75:105-115. View Abstract
  75. A benchmark concentration analysis for manganese in drinking water and IQ deficits in children. Environ Int. 2019 09; 130:104889. View Abstract
  76. Erratum: Prenatal and Childhood Traffic-Related Pollution Exposure and Childhood Cognition in the Project Viva Cohort (Massachusetts, USA). Environ Health Perspect. 2019 Jun; 127(6):69001. View Abstract
  77. Antenatal active maternal asthma and other atopic disorders is associated with ADHD behaviors among school-aged children. Brain Behav Immun. 2019 08; 80:871-878. View Abstract
  78. Failure to validate association of mannose-binding lectin deficiency with adverse neurodevelopmental outcomes after cardiac surgery in infants. J Thorac Cardiovasc Surg. 2019 Jun; 157(6):e397-e398. View Abstract
  79. Neurotoxicity of general anesthetics in children: evidence and uncertainties. Curr Opin Pediatr. 2019 04; 31(2):267-273. View Abstract
  80. Improving neurodevelopmental outcomes in children with congenital heart disease: protocol for a randomised controlled trial of working memory training. BMJ Open. 2019 02 19; 9(2):e023304. View Abstract
  81. Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. Lancet. 2019 02 16; 393(10172):664-677. View Abstract
  82. Effect of Maternal Vitamin B12 Supplementation on Cognitive Outcomes in South Indian Children: A Randomized Controlled Clinical Trial. Matern Child Health J. 2019 Feb; 23(2):155-163. View Abstract
  83. Visual-spatial processing style is associated with psychopathology in adolescents with critical congenital heart disease. Clin Neuropsychol. 2019 05; 33(4):760-778. View Abstract
  84. Estimates of the 2015 global and regional disease burden from four foodborne metals - arsenic, cadmium, lead and methylmercury. Environ Res. 2019 07; 174:188-194. View Abstract
  85. Global burden of intellectual disability resulting from prenatal exposure to methylmercury, 2015. Environ Res. 2019 03; 170:416-421. View Abstract
  86. Nutritional, Socioeconomic, and Delivery Characteristics Are Associated with Neurodevelopment in Tanzanian Children. J Pediatr. 2019 04; 207:71-79.e8. View Abstract
  87. Retraction notice to "Paraoxonase I polymorphisms and attention/hyperactivity in school-age children from Mexico City, Mexico" Environmental Research (2014) 342 -349. Environ Res. 2018 11; 167:776. View Abstract
  88. Longitudinal Associations between Neurodevelopment and Psychosocial Health Status in Patients with Repaired D-Transposition of the Great Arteries. J Pediatr. 2019 01; 204:38-45.e1. View Abstract
  89. Concussion History and Cognitive Function in a Large Cohort of Adolescent Athletes. Am J Sports Med. 2018 11; 46(13):3262-3270. View Abstract
  90. Bayesian varying coefficient kernel machine regression to assess neurodevelopmental trajectories associated with exposure to complex mixtures. Stat Med. 2018 12 30; 37(30):4680-4694. View Abstract
  91. Lead in Air in Bangladesh: Exposure in a Rural Community with Elevated Blood Lead Concentrations among Young Children. Int J Environ Res Public Health. 2018 09 06; 15(9). View Abstract
  92. Prenatal lead exposure modifies the association of maternal self-esteem with child adaptive ability. Int J Hyg Environ Health. 2019 01; 222(1):68-75. View Abstract
  93. Identification of novel loci associated with infant cognitive ability. Mol Psychiatry. 2020 11; 25(11):3010-3019. View Abstract
  94. Is Dental Amalgam Toxic to Children of Color? J Natl Med Assoc. 2018 Aug; 110(4):414-416. View Abstract
  95. Growth parameters at birth mediate the relationship between prenatal manganese exposure and cognitive test scores among a cohort of 2- to 3-year-old Bangladeshi children. Int J Epidemiol. 2018 08 01; 47(4):1169-1179. View Abstract
  96. Perioperative Exposure to Suspect Neurotoxicants From Medical Devices in Newborns With Congenital Heart Defects. Ann Thorac Surg. 2019 02; 107(2):567-572. View Abstract
  97. Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment. Environ Int. 2018 10; 119:527-535. View Abstract
  98. Lagged kernel machine regression for identifying time windows of susceptibility to exposures of complex mixtures. Biostatistics. 2018 07 01; 19(3):325-341. View Abstract
  99. Altered White Matter Microstructure Correlates with IQ and Processing Speed in Children and Adolescents Post-Fontan. J Pediatr. 2018 09; 200:140-149.e4. View Abstract
  100. Applying methods of the global burden of diseases, injuries, and risk factors study to developmental neurotoxicants: a commentary. Environ Health. 2018 06 04; 17(1):53. View Abstract
  101. Markers of Environmental Enteric Dysfunction Are Associated With Neurodevelopmental Outcomes in Tanzanian Children. J Pediatr Gastroenterol Nutr. 2018 Jun; 66(6):953-959. View Abstract
  102. Prenatal and childhood exposure to per- and polyfluoroalkyl substances (PFASs) and child cognition. Environ Int. 2018 06; 115:358-369. View Abstract
  103. Lower C-reactive protein and IL-6 associated with vegetarian diets are mediated by BMI. Nutr Metab Cardiovasc Dis. 2018 08; 28(8):787-794. View Abstract
  104. n-3 Fatty Acid Supplementation in Mothers, Preterm Infants, and Term Infants and Childhood Psychomotor and Visual Development: A Systematic Review and Meta-Analysis. J Nutr. 2018 03 01; 148(3):409-418. View Abstract
  105. Does early vitamin B12 supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania. BMJ Open. 2018 02 22; 8(2):e018962. View Abstract
  106. Announcing the 2018 Toxics Travel Award for Post-Doctoral Fellows. Toxics. 2018 Jan 30; 6(1). View Abstract
  107. Blood and Hair Aluminum Levels, Vaccine History, and Early Infant Development: A Cross-Sectional Study. Acad Pediatr. 2018 03; 18(2):161-165. View Abstract
  108. Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study-A Prospective Randomized Trial). Anesth Analg. 2017 09; 125(3):837-845. View Abstract
  109. Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis. Environ Health Perspect. 2017 08 03; 125(8):086001. View Abstract
  110. Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment. Environ Health. 2017 07 28; 16(1):81. View Abstract
  111. Anthropometric measures at birth and early childhood are associated with neurodevelopmental outcomes among Bangladeshi children aged 2-3years. Sci Total Environ. 2017 Dec 31; 607-608:475-482. View Abstract
  112. Paternal and maternal preconception urinary phthalate metabolite concentrations and child behavior. Environ Res. 2017 10; 158:720-728. View Abstract
  113. Prenatal environmental chemical exposures and longitudinal patterns of child neurobehavior. Neurotoxicology. 2017 Sep; 62:192-199. View Abstract
  114. Prenatal co-exposure to manganese and depression and 24-months neurodevelopment. Neurotoxicology. 2018 01; 64:134-141. View Abstract
  115. Establishing and Achieving National Goals for Preventing Lead Toxicity and Exposure in Children. JAMA Pediatr. 2017 07 01; 171(7):616-618. View Abstract
  116. Maternal and Cord Blood Manganese Concentrations and Early Childhood Neurodevelopment among Residents near a Mining-Impacted Superfund Site. Environ Health Perspect. 2017 06 28; 125(6):067020. View Abstract
  117. The Joint Effect of Prenatal Exposure to Metal Mixtures on Neurodevelopmental Outcomes at 20-40 Months of Age: Evidence from Rural Bangladesh. Environ Health Perspect. 2017 06 26; 125(6):067015. View Abstract
  118. Learning and Memory in Adolescents With Critical Biventricular Congenital Heart Disease. J Int Neuropsychol Soc. 2017 09; 23(8):627-639. View Abstract
  119. Psychiatric Disorders and Function in Adolescents with Tetralogy of Fallot. J Pediatr. 2017 08; 187:165-173. View Abstract
  120. Childhood Lead Exposure and Adult Outcomes. JAMA. 2017 03 28; 317(12):1219-1220. View Abstract
  121. Neuropsychological and Psychiatric Outcomes in Dextro-Transposition of the Great Arteries across the Lifespan: A State-of-the-Art Review. Front Pediatr. 2017; 5:59. View Abstract
  122. Visuospatial processing in adolescents with critical congenital heart disease: Organization, integration, and implications for academic achievement. Child Neuropsychol. 2018 05; 24(4):451-468. View Abstract
  123. Development and validation of an early childhood development scale for use in low-resourced settings. Popul Health Metr. 2017 02 09; 15(1):3. View Abstract
  124. Psychiatric Disorders in Adolescents With Single Ventricle Congenital Heart Disease. Pediatrics. 2017 Mar; 139(3). View Abstract
  125. Prenatal phthalate, triclosan, and bisphenol A exposures and child visual-spatial abilities. Neurotoxicology. 2017 01; 58:75-83. View Abstract
  126. Mechanistic Pathways From Early Gestation Through Infancy and Neurodevelopment. Pediatrics. 2016 12; 138(6). View Abstract
  127. Maternal stress modifies the effect of exposure to lead during pregnancy and 24-month old children's neurodevelopment. Environ Int. 2017 Jan; 98:191-197. View Abstract
  128. White Matter Volume Predicts Language Development in Congenital Heart Disease. J Pediatr. 2017 02; 181:42-48.e2. View Abstract
  129. Stunting is associated with blood lead concentration among Bangladeshi children aged 2-3 years. Environ Health. 2016 11 04; 15(1):103. View Abstract
  130. Early-Term Birth in Single-Ventricle Congenital Heart Disease After the Fontan Procedure: Neurodevelopmental and Psychiatric Outcomes. J Pediatr. 2016 12; 179:96-103. View Abstract
  131. Maternal prenatal fish consumption and cognition in mid childhood: Mercury, fatty acids, and selenium. Neurotoxicol Teratol. 2016 Sep - Oct; 57:71-78. View Abstract
  132. Project TENDR: Targeting Environmental Neuro-Developmental Risks The TENDR Consensus Statement. Environ Health Perspect. 2016 07 01; 124(7):A118-22. View Abstract
  133. Effects of maternal vitamin B12 supplementation on early infant neurocognitive outcomes: a randomized controlled clinical trial. Matern Child Nutr. 2017 04; 13(2). View Abstract
  134. Prenatal and childhood traffic-related air pollution exposure and childhood executive function and behavior. Neurotoxicol Teratol. 2016 Sep - Oct; 57:60-70. View Abstract
  135. Toddler temperament and prenatal exposure to lead and maternal depression. Environ Health. 2016 06 16; 15(1):71. View Abstract
  136. Organizational topology of brain and its relationship to ADHD in adolescents with d-transposition of the great arteries. Brain Behav. 2016 08; 6(8):e00504. View Abstract
  137. Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood. JAMA. 2016 Jun 07; 315(21):2312-20. View Abstract
  138. A developmental perspective on early-life exposure to neurotoxicants. Environ Int. 2016 Sep; 94:103-112. View Abstract
  139. The effect of daily zinc and/or multivitamin supplements on early childhood development in Tanzania: results from a randomized controlled trial. Matern Child Nutr. 2017 04; 13(2). View Abstract
  140. Processing speed, executive function, and academic achievement in children with dextro-transposition of the great arteries: Testing a longitudinal developmental cascade model. Neuropsychology. 2016 10; 30(7):874-885. View Abstract
  141. Neurodevelopmental outcomes among 2- to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water. Environ Health. 2016 Mar 12; 15:44. View Abstract
  142. Country-specific estimates of the incidence of intellectual disability associated with prenatal exposure to methylmercury. Environ Res. 2016 May; 147:159-63. View Abstract
  143. Lead Contamination in Flint--An Abject Failure to Protect Public Health. N Engl J Med. 2016 Mar 24; 374(12):1101-3. View Abstract
  144. Prenatal Arsenic Exposure and Birth Outcomes among a Population Residing near a Mining-Related Superfund Site. Environ Health Perspect. 2016 08; 124(8):1308-15. View Abstract
  145. Infant Breastfeeding Duration and Mid-Childhood Executive Function, Behavior, and Social-Emotional Development. J Dev Behav Pediatr. 2016 Jan; 37(1):43-52. View Abstract
  146. Environment and Brain Development: Challenges in the Global Context. Neuroepidemiology. 2016; 46(2):79-82. View Abstract
  147. Neuropsychological Status and Structural Brain Imaging in Adolescents With Single Ventricle Who Underwent the Fontan Procedure. J Am Heart Assoc. 2015 Dec 14; 4(12). View Abstract
  148. Neurological and neuropsychological functions in adults with a history of developmental arsenic poisoning from contaminated milk powder. Neurotoxicol Teratol. 2016 Jan-Feb; 53:75-80. View Abstract
  149. World Health Organization estimates of the global and regional disease burden of four foodborne chemical toxins, 2010: a data synthesis. F1000Res. 2015; 4:1393. View Abstract
  150. Methodological Framework for World Health Organization Estimates of the Global Burden of Foodborne Disease. PLoS One. 2015; 10(12):e0142498. View Abstract
  151. World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010. PLoS Med. 2015 Dec; 12(12):e1001923. View Abstract
  152. Prenatal particulate air pollution and neurodevelopment in urban children: Examining sensitive windows and sex-specific associations. Environ Int. 2016 Feb; 87:56-65. View Abstract
  153. Associations between Prenatal Exposure to Black Carbon and Memory Domains in Urban Children: Modification by Sex and Prenatal Stress. PLoS One. 2015; 10(11):e0142492. View Abstract
  154. Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. Lancet. 2016 Jan 16; 387(10015):239-50. View Abstract
  155. Malnutrition and Its Determinants Are Associated with Suboptimal Cognitive, Communication, and Motor Development in Tanzanian Children. J Nutr. 2015 Dec; 145(12):2705-14. View Abstract
  156. Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives. Endocrinology. 2015 Oct; 156(10):3408-15. View Abstract
  157. Predictors of Failure of Awake Regional Anesthesia for Neonatal Hernia Repair: Data from the General Anesthesia Compared to Spinal Anesthesia Study--Comparing Apnea and Neurodevelopmental Outcomes. Anesthesiology. 2015 Jul; 123(1):55-65. View Abstract
  158. Executive function deficits in congenital heart disease: why is intervention important? Cardiol Young. 2015 Oct; 25(7):1238-46. View Abstract
  159. Prenatal Lead Exposure Modifies the Impact of Maternal Self-Esteem on Children's Inattention Behavior. J Pediatr. 2015 Aug; 167(2):435-41. View Abstract
  160. Comment on "Severe dental fluorosis and cognitive deficits". Neurotoxicol Teratol. 2015 Jul-Aug; 50:32. View Abstract
  161. Neurodevelopmental outcomes after cardiac surgery in infancy. Pediatrics. 2015 May; 135(5):816-25. View Abstract
  162. Prenatal and Childhood Traffic-Related Pollution Exposure and Childhood Cognition in the Project Viva Cohort (Massachusetts, USA). Environ Health Perspect. 2015 Oct; 123(10):1072-8. View Abstract
  163. Measured Prenatal and Estimated Postnatal Levels of Polychlorinated Biphenyls (PCBs) and ADHD-Related Behaviors in 8-Year-Old Children. Environ Health Perspect. 2015 Sep; 123(9):888-94. View Abstract
  164. Relationship of white matter network topology and cognitive outcome in adolescents with d-transposition of the great arteries. Neuroimage Clin. 2015; 7:438-48. View Abstract
  165. Of decrements and disorders: assessing impairments in neurodevelopment in prospective studies of environmental toxicant exposures. Environ Health. 2015 Jan 21; 14:8. View Abstract
  166. Executive Function in Children and Adolescents with Critical Cyanotic Congenital Heart Disease. J Int Neuropsychol Soc. 2015 Jan; 21(1):34-49. View Abstract
  167. Association of lifetime exposure to fluoride and cognitive functions in Chinese children: a pilot study. Neurotoxicol Teratol. 2015 Jan-Feb; 47:96-101. View Abstract
  168. Predictors of health-related quality of life in adolescents with tetralogy of Fallot. J Pediatr. 2015 Jan; 166(1):132-8. View Abstract
  169. Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study. Environ Health. 2014 Oct 06; 13:77. View Abstract
  170. Neurobehavioral function in school-age children exposed to manganese in drinking water. Environ Health Perspect. 2014 Dec; 122(12):1343-50. View Abstract
  171. White matter microstructure and cognition in adolescents with congenital heart disease. J Pediatr. 2014 Nov; 165(5):936-44.e1-2. View Abstract
  172. Contaminated turmeric is a potential source of lead exposure for children in rural Bangladesh. J Environ Public Health. 2014; 2014:730636. View Abstract
  173. Prenatal organochlorine and methylmercury exposure and memory and learning in school-age children in communities near the New Bedford Harbor Superfund site, Massachusetts. Environ Health Perspect. 2014 Nov; 122(11):1253-9. View Abstract
  174. Validation of association of the apolipoprotein E e2 allele with neurodevelopmental dysfunction after cardiac surgery in neonates and infants. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2560-6. View Abstract
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  363. Biologically based, quantitative risk assessment of neurotoxicants. Fundam Appl Toxicol. 1996 Jan; 29(1):18-30. View Abstract
  364. A longitudinal study of chronic lead exposure and physical growth in Boston children. Environ Health Perspect. 1995 Oct; 103(10):952-7. View Abstract
  365. Models of delayed recovery. J Child Neurol. 1995 Sep; 10(5):385-91. View Abstract
  366. Interpreting the literature on lead and child development: the neglected role of the "experimental system". Neurotoxicol Teratol. 1995 May-Jun; 17(3):201-12. View Abstract
  367. von Willebrand factor in plasma, platelets, and selected tissues of ferrets. Lab Anim Sci. 1995 Apr; 45(2):151-9. View Abstract
  368. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. N Engl J Med. 1995 Mar 02; 332(9):549-55. View Abstract
  369. Neuropsychologic function in children exposed to environmental lead. Epidemiology. 1995 Mar; 6(2):101-3. View Abstract
  370. Low-level lead exposure and cognitive function in children. Pediatr Ann. 1994 Nov; 23(11):600-5. View Abstract
  371. The impact of soil lead abatement on urban children's blood lead levels: phase II results from the Boston Lead-In-Soil Demonstration Project. Environ Res. 1994 Nov; 67(2):125-48. View Abstract
  372. Teratogen update: lead. Teratology. 1994 Nov; 50(5):367-73. View Abstract
  373. Pre- and postnatal lead exposure and behavior problems in school-aged children. Environ Res. 1994 Jul; 66(1):12-30. View Abstract
  374. Attentional correlates of dentin and bone lead levels in adolescents. Arch Environ Health. 1994 Mar-Apr; 49(2):98-105. View Abstract
  375. Children with hypoplastic enamel defects of primary incisors are not at increased risk of learning-problem syndromes. ASDC J Dent Child. 1994 Jan-Feb; 61(1):35-8. View Abstract
  376. Relationships between serial blood lead levels and exfoliated tooth dentin lead levels: models of tooth lead kinetics. Calcif Tissue Int. 1993 Nov; 53(5):338-41. View Abstract
  377. Relation of pH strategy and developmental outcome after hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 1993 Aug; 106(2):362-8. View Abstract
  378. Epidemiologic approaches to assessing the developmental toxicity of lead. Neurotoxicology. 1993 Summer-Fall; 14(2-3):151-60. View Abstract
  379. Lead-contaminated soil abatement and urban children's blood lead levels. JAMA. 1993 Apr 07; 269(13):1647-54. View Abstract
  380. Neuropsychological correlates of low-level lead exposure in school-age children: a prospective study. Neurotoxicol Teratol. 1993 Jan-Feb; 15(1):27-35. View Abstract
  381. Pre- and postnatal low-level lead exposure and children's dysfunction in school. Environ Res. 1993 Jan; 60(1):30-43. View Abstract
  382. The Boston Teacher Questionnaire. 3. A reassessment. J Child Neurol. 1993 Jan; 8(1):64-72. View Abstract
  383. Low-level lead exposure, intelligence and academic achievement: a long-term follow-up study. Pediatrics. 1992 Dec; 90(6):855-61. View Abstract
  384. Antecedents and correlates of hypoplastic enamel defects of primary incisors. Pediatr Dent. 1992 May-Jun; 14(3):158-66. View Abstract
  385. Pre-natal blood lead levels and learning difficulties in children: an analysis of non-randomly missing categorical data. Stat Med. 1992 Apr; 11(6):799-811. View Abstract
  386. The goal: safety and equality. Am J Ind Med. 1992; 21(4):463-5. View Abstract
  387. Lead correction. Nature. 1991 Nov 07; 354(6348):26. View Abstract
  388. Lead levels among various deciduous tooth types. Bull Environ Contam Toxicol. 1991 Oct; 47(4):602-8. View Abstract
  389. Cognitive development of children following early repair of transposition of the great arteries using deep hypothermic circulatory arrest. Pediatrics. 1991 May; 87(5):701-7. View Abstract
  390. Weight gain and maturity in fetuses exposed to low levels of lead. Environ Res. 1991 Apr; 54(2):151-8. View Abstract
  391. Low-level lead exposure and children's cognitive function in the preschool years. Pediatrics. 1991 Feb; 87(2):219-27. View Abstract
  392. The health effects of low level exposure to lead. Annu Rev Public Health. 1991; 12:111-40. View Abstract
  393. Antecedents and correlates of improved cognitive performance in children exposed in utero to low levels of lead. Environ Health Perspect. 1990 Nov; 89:5-11. View Abstract
  394. Coronary atherosclerosis in the pig. Induced plaque injury and platelet response. Arteriosclerosis. 1990 Jul-Aug; 10(4):541-50. View Abstract
  395. Lead and childhood propensity to infectious and allergic disorders: is there an association? Bull Environ Contam Toxicol. 1990 May; 44(5):657-60. View Abstract
  396. In utero lead exposure. MCN Am J Matern Child Nurs. 1990 Mar-Apr; 15(2):94-6. View Abstract
  397. The long-term effects of exposure to low doses of lead in childhood. An 11-year follow-up report. N Engl J Med. 1990 Jan 11; 322(2):83-8. View Abstract
  398. Infantile colic and transient developmental lag in the first year of life. Child Psychiatry Hum Dev. 1990; 21(1):25-36. View Abstract
  399. Blood lead--tooth lead relationship among Boston children. Bull Environ Contam Toxicol. 1989 Oct; 43(4):485-92. View Abstract
  400. Lead, IQ and social class. Int J Epidemiol. 1989 Mar; 18(1):180-5. View Abstract
  401. Prenatal/early postnatal exposure to lead and risk of developmental impairment. Birth Defects Orig Artic Ser. 1989; 25(6):73-97. View Abstract
  402. Soil lead-blood lead relationship among Boston children. Bull Environ Contam Toxicol. 1988 Dec; 41(6):791-7. View Abstract
  403. Low-level lead exposure, social class, and infant development. Neurotoxicol Teratol. 1988 Nov-Dec; 10(6):497-503. View Abstract
  404. Recent developments: UAW vs Johnson control. Environ Res. 1988 Aug; 46(2):190-1. View Abstract
  405. Pregnancy hypertension, blood pressure during labor, and blood lead levels. Hypertension. 1987 Oct; 10(4):447-51. View Abstract
  406. Longitudinal analyses of prenatal and postnatal lead exposure and early cognitive development. N Engl J Med. 1987 Apr 23; 316(17):1037-43. View Abstract
  407. Correlates of low-level lead exposure in urban children at 2 years of age. Pediatrics. 1986 Jun; 77(6):826-33. View Abstract
  408. Low-level lead exposure and infant development in the first year. Neurobehav Toxicol Teratol. 1986 Mar-Apr; 8(2):151-61. View Abstract
  409. Consequences of unremitting middle-ear infection in early life. N Engl J Med. 1985 Nov 21; 313(21):1353-4. View Abstract
  410. Methodological issues in modeling the relationship between low-level lead exposure and infant development: examples from the Boston Lead Study. Environ Res. 1985 Oct; 38(1):119-29. View Abstract
  411. Environmental correlates of infant blood lead levels in Boston. Environ Res. 1985 Oct; 38(1):96-107. View Abstract
  412. Home refinishing, lead paint, and infant blood lead levels. Am J Public Health. 1985 Apr; 75(4):403-4. View Abstract
  413. Early sensory-motor development and prenatal exposure to lead. Neurobehav Toxicol Teratol. 1984 Sep-Oct; 6(5):387-402. View Abstract
  414. A followup study of the academic attainment and classroom behavior of children with elevated dentine lead levels. Biol Trace Elem Res. 1984 Jun; 6(3):207-23. View Abstract
  415. Lead and the relationship between maternal and child intelligence. J Pediatr. 1983 Apr; 102(4):523-7. View Abstract
  416. Lead-associated intellectual deficit. N Engl J Med. 1982 02 11; 306(6):367. View Abstract
  417. Does lead at low dose affect intelligence in children? Pediatrics. 1981 Dec; 68(6):894-6. View Abstract
  418. The epidemiology of low-level lead exposure in childhood. J Am Acad Child Psychiatry. 1981; 20(3):496-512. View Abstract
  419. Consistency in the pattern of change in mothers' speech: some discriminant analyses. J Child Lang. 1980 Oct; 7(3):469-87. View Abstract
  420. Changes in the explicitness of mothers' directives as children age. J Child Lang. 1979 Oct; 6(3):443-58. View Abstract

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