Clifford Woolf

Publications

1. ARBEL: A Machine Learning Tool with Light-Based Image Analysis for Automatic Classification of 3D Pain Behaviors. bioRxiv. 2024 Dec 02. View Abstract
2. Immune drivers of pain resolution and protection. Nat Immunol. 2024 Dec; 25(12):2200-2208. View Abstract
3. Neuroma-to-Nerve Ratio: Does Size Matter? Neurosurgery. 2024 Sep 09. View Abstract
4. A ?d T cell-IL-3 axis controls allergic responses through sensory neurons. Nature. 2024 Oct; 634(8033):440-446. View Abstract
5. Pain researchers must learn from the opioid crisis. Nature. 2024 Sep; 633(8031):S40. View Abstract
6. Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons. bioRxiv. 2024 Aug 26. View Abstract
7. Mast cell-derived BH4 and serotonin are critical mediators of postoperative pain. Sci Immunol. 2024 Aug 23; 9(98):eadh0545. View Abstract
8. Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Cell Mol Life Sci. 2024 Jul 27; 81(1):315. View Abstract
9. Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2024 07 17; 112(14):2452. View Abstract
10. Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2024 Jul 17; 112(14):2453-2456. View Abstract
11. Identification of novel neuroprotectants against vincristine-induced neurotoxicity in iPSC-derived neurons. Res Sq. 2024 Jul 02. View Abstract
12. Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia. Sci Adv. 2024 Jun 21; 10(25):eadj9173. View Abstract
13. Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis. Brain Commun. 2024; 6(3):fcae202. View Abstract
14. Nociceptor-immune interactomes reveal insult-specific immune signatures of pain. Nat Immunol. 2024 Jul; 25(7):1296-1305. View Abstract
15. Age-dependent small fiber neuropathy: Mechanistic insights from animal models. Exp Neurol. 2024 Jul; 377:114811. View Abstract
16. Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain. Sci Transl Med. 2024 Apr 17; 16(743):eadg3036. View Abstract
17. Immune drivers of physiological and pathological pain. J Exp Med. 2024 May 06; 221(5). View Abstract
18. Selective modification of ascending spinal outputs in acute and neuropathic pain states. bioRxiv. 2024 Apr 09. View Abstract
19. The secondary somatosensory cortex gates mechanical and heat sensitivity. Nat Commun. 2024 Feb 12; 15(1):1289. View Abstract
20. Macrophages protect against sensory axon degeneration in diabetic neuropathy. bioRxiv. 2024 Jan 30. View Abstract
21. Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons. Cell Rep. 2024 02 27; 43(2):113718. View Abstract
22. Bortezomib-induced neuropathy is in part mediated by the sensitization of TRPV1 channels. Commun Biol. 2023 12 05; 6(1):1228. View Abstract
23. Biology and pathophysiology of symptomatic neuromas. Pain. 2024 Mar 01; 165(3):550-564. View Abstract
24. Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to µ-opioidergic cell types. Nat Commun. 2023 09 13; 14(1):5632. View Abstract
25. The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC-derived sensory neurons. Sci Transl Med. 2023 08 09; 15(708):eadg6241. View Abstract
26. Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia. bioRxiv. 2023 Jul 05. View Abstract
27. The Secondary Somatosensory Cortex Gates Mechanical and Thermal Sensitivity. Res Sq. 2023 Jun 28. View Abstract
28. Integrin-Driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program. J Neurosci. 2023 06 28; 43(26):4775-4794. View Abstract
29. The Secondary Somatosensory Cortex Gates Mechanical and Thermal Sensitivity. bioRxiv. 2023 May 22. View Abstract
30. Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons. bioRxiv. 2023 May 08. View Abstract
31. Implementation of a Drug Screening Platform to TargetGch1 Expression in Injured Mouse Dorsal Root Ganglion Neurons. Bio Protoc. 2023 May 05; 13(9):e4666. View Abstract
32. A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages. Cells. 2023 04 19; 12(8). View Abstract
33. Scalable generation of sensory neurons from human pluripotent stem cells. Stem Cell Reports. 2023 04 11; 18(4):1030-1047. View Abstract
34. Nav1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation. Exp Neurol. 2023 06; 364:114393. View Abstract
35. Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV + interneurons. bioRxiv. 2023 Mar 21. View Abstract
36. Macrophages set the bar for acute pain sensitivity. Nat Immunol. 2023 03; 24(3):382-384. View Abstract
37. Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways. bioRxiv. 2023 Feb 03. View Abstract
38. Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2023 Feb 01; 111(3):444. View Abstract
39. Mast cell-derived BH4 is a critical mediator of postoperative pain. bioRxiv. 2023 Jan 24. View Abstract
40. The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors. Br J Pharmacol. 2023 04; 180(8):1148-1167. View Abstract
41. ß-Endorphin mediates radiation therapy fatigue. Sci Adv. 2022 Dec 16; 8(50):eabn6025. View Abstract
42. Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion. Dis Model Mech. 2022 12 01; 15(12). View Abstract
43. Nociceptor neurons affect cancer immunosurveillance. Nature. 2022 Nov; 611(7935):405-412. View Abstract
44. Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations. J Pain. 2023 02; 24(2):204-225. View Abstract
45. Pain modulation in the spinal cord. Front Pain Res (Lausanne). 2022; 3:984042. View Abstract
46. Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer. Sci Transl Med. 2022 08 31; 14(660):eabj1531. View Abstract
47. Development of a PET radioligand for a2d-1 subunit of calcium channels for imaging neuropathic pain. Eur J Med Chem. 2022 Nov 15; 242:114688. View Abstract
48. Cryoneurolysis with Injectable Ice Slurry Modulates Mechanical Skin Pain. J Invest Dermatol. 2023 01; 143(1):134-141.e1. View Abstract
49. Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration in mice. Nat Commun. 2022 07 29; 13(1):4418. View Abstract
50. Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions. Cell Rep. 2022 07 19; 40(3):111130. View Abstract
51. Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2022 08 17; 110(16):2607-2624.e8. View Abstract
52. Structural imaging studies of patients with chronic pain: an anatomical likelihood estimate meta-analysis. Pain. 2023 01 01; 164(1):e10-e24. View Abstract
53. Automated preclinical detection of mechanical pain hypersensitivity and analgesia. Pain. 2022 12 01; 163(12):2326-2336. View Abstract
54. Cannabidiol activates neuronal Kv7 channels. Elife. 2022 02 18; 11. View Abstract
55. Nociceptor neurons promote IgE class switch in B cells. JCI Insight. 2021 12 22; 6(24). View Abstract
56. A multiparametric activity profiling platform for neuron disease phenotyping and drug screening. Mol Biol Cell. 2022 05 15; 33(6):ar54. View Abstract
57. Developing nociceptor-selective treatments for acute and chronic pain. Sci Transl Med. 2021 11 10; 13(619):eabj9837. View Abstract
58. Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. Cell Rep. 2021 09 07; 36(10):109666. View Abstract
59. DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels. Elife. 2021 09 02; 10. View Abstract
60. Dissecting the precise nature of itch-evoked scratching. Neuron. 2021 10 06; 109(19):3075-3087.e2. View Abstract
61. Promoting Long-Term Cultivation of Motor Neurons for 3D Neuromuscular Junction Formation of 3D In Vitro Using Central-Nervous-Tissue-Derived Bioink. Adv Healthc Mater. 2021 09; 10(18):e2100581. View Abstract
62. Isolation of Nuclei from Mouse Dorsal Root Ganglia for Single-nucleus Genomics. Bio Protoc. 2021 Aug 05; 11(15):e4102. View Abstract
63. Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker. Br J Pharmacol. 2021 10; 178(19):3905-3923. View Abstract
64. Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation. Cell Rep. 2021 06 08; 35(10):109224. View Abstract
65. Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype. Pain. 2021 06 01; 162(6):1758-1770. View Abstract
66. Human cells and networks of pain: Transforming pain target identification and therapeutic development. Neuron. 2021 05 05; 109(9):1426-1429. View Abstract
67. Reduced MC4R signaling alters nociceptive thresholds associated with red hair. Sci Adv. 2021 04; 7(14). View Abstract
68. Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial. JAMA Neurol. 2021 02 01; 78(2):186-196. View Abstract
69. Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations. Pain Rep. 2021; 6(1):e895. View Abstract
70. FceR1-expressing nociceptors trigger allergic airway inflammation. J Allergy Clin Immunol. 2021 06; 147(6):2330-2342. View Abstract
71. Brain Responses to Noxious Stimuli in Patients With Chronic Pain: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021 01 04; 4(1):e2032236. View Abstract
72. Epineural optogenetic activation of nociceptors initiates and amplifies inflammation. Nat Biotechnol. 2021 02; 39(2):179-185. View Abstract
73. Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury. Neuron. 2020 10 14; 108(1):128-144.e9. View Abstract
74. Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs. Pain. 2020 06; 161(6):1321-1331. View Abstract
75. Vagal sensory neurons drive mucous cell metaplasia. J Allergy Clin Immunol. 2020 06; 145(6):1693-1696.e4. View Abstract
76. Unraveling the Plastic Peripheral Neuroimmune Interactome. J Immunol. 2020 01 15; 204(2):257-263. View Abstract
77. Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis. Neurosci Biobehav Rev. 2020 05; 112:300-323. View Abstract
78. Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice. Arthritis Rheumatol. 2020 01; 72(1):57-66. View Abstract
79. Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation. Elife. 2019 11 25; 8. View Abstract
80. The Role of Iron Regulation in Immunometabolism and Immune-Related Disease. Front Mol Biosci. 2019; 6:116. View Abstract
81. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 2019 11 27; 179(6):1342-1356.e23. View Abstract
82. Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. 2019 Aug; 572(7769):E18. View Abstract
83. Capturing Novel Non-opioid Pain Targets. Biol Psychiatry. 2020 01 01; 87(1):74-81. View Abstract
84. Composite Pain Biomarker Signatures for Objective Assessment and Effective Treatment. Neuron. 2019 03 06; 101(5):783-800. View Abstract
85. ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair. Nat Neurosci. 2019 02; 22(2):167-179. View Abstract
86. Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation. Stem Cell Reports. 2019 01 08; 12(1):29-41. View Abstract
87. The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. 2018 11; 563(7732):564-568. View Abstract
88. Author Correction: Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma. Nat Commun. 2018 09 20; 9(1):3914. View Abstract
89. Diltiazem Promotes Regenerative Axon Growth. Mol Neurobiol. 2019 Jun; 56(6):3948-3957. View Abstract
90. Touch and tactile neuropathic pain sensitivity are set by corticospinal projections. Nature. 2018 09; 561(7724):547-550. View Abstract
91. Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration. Nat Commun. 2018 08 22; 9(1):3358. View Abstract
92. Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018 08 14; 24(7):1865-1879.e9. View Abstract
93. Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma. Nat Commun. 2018 08 10; 9(1):3209. View Abstract
94. Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin. Mol Psychiatry. 2018 11; 23(11):2167-2183. View Abstract
95. Optical cuff for optogenetic control of the peripheral nervous system. J Neural Eng. 2018 02; 15(1):015002. View Abstract
96. Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling. Cell Rep. 2018 01 30; 22(5):1301-1312. View Abstract
97. Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314. Nat Commun. 2018 01 02; 9(1):37. View Abstract
98. Sense and Immunity: Context-Dependent Neuro-Immune Interplay. Front Immunol. 2017; 8:1463. View Abstract
99. Mouse embryonic stem cells can differentiate via multiple paths to the same state. Elife. 2017 10 09; 6. View Abstract
100. Breaking barriers to novel analgesic drug development. Nat Rev Drug Discov. 2017 11; 16(11):810. View Abstract
101. Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity. Cell. 2017 Nov 02; 171(4):836-848.e13. View Abstract
102. Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury. Cell Rep. 2017 08 01; 20(5):1136-1147. View Abstract
103. Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses. Cell Rep. 2017 07 05; 20(1):89-98. View Abstract
104. Breaking barriers to novel analgesic drug development. Nat Rev Drug Discov. 2017 Aug; 16(8):545-564. View Abstract
105. Decreased alertness due to sleep loss increases pain sensitivity in mice. Nat Med. 2017 Jun; 23(6):768-774. View Abstract
106. The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity. Sci Rep. 2017 03 27; 7(1):446. View Abstract
107. Time for nonaddictive relief of pain. Science. 2017 Mar 10; 355(6329):1026-1027. View Abstract
108. Substance P activates Mas-related G protein-coupled receptors to induce itch. J Allergy Clin Immunol. 2017 Aug; 140(2):447-453.e3. View Abstract
109. Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes. Bioelectron Med. 2016; 3:18-28. View Abstract
110. Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):12544-12549. View Abstract
111. Toward a Mechanism-Based Approach to Pain Diagnosis. J Pain. 2016 09; 17(9 Suppl):T50-69. View Abstract
112. Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size. Cell Rep. 2016 08 09; 16(6):1664-1676. View Abstract
113. Pain and infection: pathogen detection by nociceptors. Pain. 2016 06; 157(6):1192-1193. View Abstract
114. Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron. 2016 May 04; 90(3):662. View Abstract
115. Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations. Pain. 2016 Apr; 157(4):901-909. View Abstract
116. Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition. Sci Signal. 2016 Mar 29; 9(421):ra32. View Abstract
117. Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Rheumatol. 2016 Mar; 68(3):654-61. View Abstract
118. Neuroimmunity: Physiology and Pathology. Annu Rev Immunol. 2016 05 20; 34:421-47. View Abstract
119. A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. 2016 Mar 02; 89(5):956-70. View Abstract
120. CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):E6808-17. View Abstract
121. Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms. Neuron. 2015 Nov 18; 88(4):704-19. View Abstract
122. Lack of motor recovery after prolonged denervation of the neuromuscular junction is not due to regenerative failure. Eur J Neurosci. 2016 Feb; 43(3):451-62. View Abstract
123. The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex. J Neurosci. 2015 Jul 29; 35(30):10762-72. View Abstract
124. From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial. Cell Stem Cell. 2015 Jul 02; 17(1):8-10. View Abstract
125. Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations. Pain. 2015 Jul; 156(7):1184-1197. View Abstract
126. Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation. Neuron. 2015 Jul 15; 87(2):341-54. View Abstract
127. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway. Neuron. 2015 Jun 17; 86(6):1393-406. View Abstract
128. Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron. 2015 Jun 03; 86(5):1215-27. View Abstract
129. Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics. Neuron. 2015 May 20; 86(4):1000-1014. View Abstract
130. The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase. Nat Med. 2015 May; 21(5):518-23. View Abstract
131. CNS injury: IL-33 sounds the alarm. Immunity. 2015 Mar 17; 42(3):403-5. View Abstract
132. Correction: Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. Elife. 2015 Feb 06; 4:e06720. View Abstract
133. Early psychological reactions in parents of children with a life threatening illness within a pediatric hospital setting. Eur Psychiatry. 2015 Jul; 30(5):555-61. View Abstract
134. Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity. Elife. 2014 Dec 19; 3. View Abstract
135. Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts. Nat Neurosci. 2015 Jan; 18(1):17-24. View Abstract
136. A three-dimensional human neural cell culture model of Alzheimer's disease. Nature. 2014 Nov 13; 515(7526):274-8. View Abstract
137. Ronald R. Tasker Young Investigator Award 165 Promoting Endogenous GABAergic Analgesia via Kinase Modulation of Neuronal Ion Plasticity. Neurosurgery. 2014 Aug; 61 Suppl 1:214. View Abstract
138. What to call the amplification of nociceptive signals in the central nervous system that contribute to widespread pain? Pain. 2014 Oct; 155(10):1911-1912. View Abstract
139. Diminished Schwann cell repair responses underlie age-associated impaired axonal regeneration. Neuron. 2014 Jul 16; 83(2):331-343. View Abstract
140. Skin ß-endorphin mediates addiction to UV light. Cell. 2014 Jun 19; 157(7):1527-34. View Abstract
141. Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain. JAMA Neurol. 2014 May; 71(5):640-5. View Abstract
142. Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 2014 Jun 05; 14(6):781-95. View Abstract
143. Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons. Cell Rep. 2014 Apr 10; 7(1):1-11. View Abstract
144. Casting light on pain. Nat Biotechnol. 2014 Mar; 32(3):240-1. View Abstract
145. ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1622-7. View Abstract
146. Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block. Br J Pharmacol. 2014 Jan; 171(2):438-51. View Abstract
147. Sensitivity and sensitisation in relation to pain severity in knee osteoarthritis: trait or state? Ann Rheum Dis. 2015 Apr; 74(4):682-8. View Abstract
148. Bacteria activate sensory neurons that modulate pain and inflammation. Nature. 2013 Sep 05; 501(7465):52-7. View Abstract
149. Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons. Nat Neurosci. 2013 Jul; 16(7):910-8. View Abstract
150. A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS. Cell Stem Cell. 2013 Jun 06; 12(6):713-26. View Abstract
151. CLP1 links tRNA metabolism to progressive motor-neuron loss. Nature. 2013 Mar 28; 495(7442):474-80. View Abstract
152. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr; 9(4):257-63. View Abstract
153. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. J Pain. 2013 Feb; 14(2):103-13. View Abstract
154. Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314. J Neurophysiol. 2013 Apr; 109(7):1704-12. View Abstract
155. Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing. J Neurosci. 2013 Jan 02; 33(1):315-26. View Abstract
156. Pain: morphine, metabolites, mambas, and mutations. Lancet Neurol. 2013 Jan; 12(1):18-20. View Abstract
157. Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. PLoS Genet. 2012; 8(12):e1003071. View Abstract
158. Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology. Nat Neurosci. 2012 Jul 26; 15(8):1063-7. View Abstract
159. Overexpression of human HSP27 protects sensory neurons from diabetes. Neurobiol Dis. 2012 Sep; 47(3):436-43. View Abstract
160. 5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals. J Neurosci. 2012 May 02; 32(18):6364-72. View Abstract
161. Understanding chronic inflammatory and neuropathic pain. Ann N Y Acad Sci. 2012 May; 1255:30-44. View Abstract
162. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity. Nat Med. 2012 Mar 25; 18(4):595-9. View Abstract
163. Deconstructing the neuropathic pain phenotype to reveal neural mechanisms. Neuron. 2012 Feb 23; 73(4):638-52. View Abstract
164. Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia. Pain. 2012 Apr; 153(4):876-884. View Abstract
165. Analgesia by inhibiting tetrahydrobiopterin synthesis. Curr Opin Pharmacol. 2012 Feb; 12(1):92-9. View Abstract
166. The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling. J Neurosci. 2011 Dec 14; 31(50):18391-400. View Abstract
167. Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation. Mol Pain. 2011 Oct 04; 7:78. View Abstract
168. Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice. J Clin Invest. 2011 Nov; 121(11):4332-47. View Abstract
169. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell. 2011 Sep 02; 9(3):205-18. View Abstract
170. Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review. Br J Pharmacol. 2011 Sep; 164(1):48-58. View Abstract
171. TrpA1 regulates thermal nociception in Drosophila. PLoS One. 2011; 6(8):e24343. View Abstract
172. Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy. Pain. 2011 Aug; 152(8):1705-1708. View Abstract
173. A functionally characterized test set of human induced pluripotent stem cells. Nat Biotechnol. 2011 Mar; 29(3):279-86. View Abstract
174. A genome-wide Drosophila screen for heat nociception identifies a2d3 as an evolutionarily conserved pain gene. Cell. 2010 Nov 12; 143(4):628-38. View Abstract
175. TRPA1 contributes to cold hypersensitivity. J Neurosci. 2010 Nov 10; 30(45):15165-74. View Abstract
176. What is this thing called pain? J Clin Invest. 2010 Nov; 120(11):3742-4. View Abstract
177. Central sensitization: implications for the diagnosis and treatment of pain. Pain. 2011 Mar; 152(3 Suppl):S2-S15. View Abstract
178. Overcoming obstacles to developing new analgesics. Nat Med. 2010 Nov; 16(11):1241-7. View Abstract
179. Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. Brain. 2010 Sep; 133(9):2519-27. View Abstract
180. Synaptic plasticity and central sensitization: author reply. J Pain. 2010 Aug; 11(8):801-3. View Abstract
181. Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron. 2010 Mar 25; 65(6):886-98. View Abstract
182. Selectively targeting pain in the trigeminal system. Pain. 2010 Jul; 150(1):29-40. View Abstract
183. Future directions in neuropathic pain therapy: closing the translational loop. Oncologist. 2010; 15 Suppl 2:24-9. View Abstract
184. T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity. J Neurosci. 2009 Nov 18; 29(46):14415-22. View Abstract
185. Overexpression of the wild-type SPT1 subunit lowers desoxysphingolipid levels and rescues the phenotype of HSAN1. J Neurosci. 2009 Nov 18; 29(46):14646-51. View Abstract
186. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain. 2009 Sep; 10(9):895-926. View Abstract
187. Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents. Anesthesiology. 2009 Jul; 111(1):127-37. View Abstract
188. Mu and delta opioid receptors diverge. Cell. 2009 Jun 12; 137(6):987-8. View Abstract
189. A novel tool for the assessment of pain: validation in low back pain. PLoS Med. 2009 Apr 07; 6(4):e1000047. View Abstract
190. Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion. Pain. 2009 Mar; 142(1-2):59-67. View Abstract
191. COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice. J Clin Invest. 2009 Feb; 119(2):287-94. View Abstract
192. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu Rev Neurosci. 2009; 32:1-32. View Abstract
193. Transient receptor potential channels: targeting pain at the source. Nat Rev Drug Discov. 2009 Jan; 8(1):55-68. View Abstract
194. Nociceptors are interleukin-1beta sensors. J Neurosci. 2008 Dec 24; 28(52):14062-73. View Abstract
195. Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve. Anesthesiology. 2008 Nov; 109(5):872-8. View Abstract
196. GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function. J Am Coll Cardiol. 2008 Jul 08; 52(2):158-65. View Abstract
197. Novel analgesic development: from target to patient or patient to target? Curr Opin Investig Drugs. 2008 Jul; 9(7):694-5. View Abstract
198. Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. J Neurosci. 2008 Apr 23; 28(17):4533-40. View Abstract
199. Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype. Eur J Pain. 2008 Nov; 12(8):1069-77. View Abstract
200. Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats. Eur J Neurosci. 2008 Feb; 27(4):937-46. View Abstract
201. Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats. Pain. 2008 Aug 15; 138(1):130-142. View Abstract
202. The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci. 2007 Nov; 10(11):1361-8. View Abstract
203. Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers. Nature. 2007 Oct 04; 449(7162):607-10. View Abstract
204. Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity. J Neurosci. 2007 Aug 08; 27(32):8699-708. View Abstract
205. Nociceptors--noxious stimulus detectors. Neuron. 2007 Aug 02; 55(3):353-64. View Abstract
206. Delayed sympathetic dependence in the spared nerve injury (SNI) model of neuropathic pain. Mol Pain. 2007 Jul 31; 3:21. View Abstract
207. ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regeneration. J Neurosci. 2007 Jul 25; 27(30):7911-20. View Abstract
208. GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord. Mol Cell Neurosci. 2007 Oct; 36(2):185-94. View Abstract
209. BACE1 regulates voltage-gated sodium channels and neuronal activity. Nat Cell Biol. 2007 Jul; 9(7):755-64. View Abstract
210. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci. 2007 Jul; 10(7):870-9. View Abstract
211. Central sensitization: uncovering the relation between pain and plasticity. Anesthesiology. 2007 Apr; 106(4):864-7. View Abstract
212. Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms. Clin Chem. 2007 Jun; 53(6):1010-5. View Abstract
213. The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. J Neurosci. 2006 Dec 13; 26(50):12852-60. View Abstract
214. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006 Nov; 12(11):1269-77. View Abstract
215. Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity. J Pharmacol Exp Ther. 2006 Dec; 319(3):1096-103. View Abstract
216. The transcription factor ATF-3 promotes neurite outgrowth. Mol Cell Neurosci. 2006 May-Jun; 32(1-2):143-54. View Abstract
217. Persistent postsurgical pain: risk factors and prevention. Lancet. 2006 May 13; 367(9522):1618-25. View Abstract
218. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron. 2006 Apr 20; 50(2):277-89. View Abstract
219. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006 May; 38(5):531-9. View Abstract
220. Perceptual wind-up in the human oesophagus is enhanced by central sensitisation. Gut. 2006 Jul; 55(7):920-5. View Abstract
221. Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 02; 49(3):365-77. View Abstract
222. Bradykinin and peripheral sensitization. Biol Chem. 2006 Jan; 387(1):11-4. View Abstract
223. Detection of cold pain, cold allodynia and cold hyperalgesia in freely behaving rats. Mol Pain. 2005 Dec 14; 1:36. View Abstract
224. RNAi blocks DYT1 mutant torsinA inclusions in neurons. Neurosci Lett. 2006 Mar 13; 395(3):201-5. View Abstract
225. Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons. J Neurosci. 2005 Nov 23; 25(47):10970-80. View Abstract
226. Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy. Hum Mol Genet. 2005 Nov 15; 14(22):3507-21. View Abstract
227. Role of the peripheral benzodiazepine receptor in sensory neuron regeneration. Mol Cell Neurosci. 2005 Oct; 30(2):228-37. View Abstract
228. Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord. Pain. 2005 Sep; 117(1-2):77-87. View Abstract
229. Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission. J Neurosci. 2005 Aug 31; 25(35):7986-92. View Abstract
230. Constitutive cyclo-oxygenase-2 does not contribute to the development of human visceral pain hypersensitivity. Eur J Pain. 2006 Aug; 10(6):487-94. View Abstract
231. Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury. J Neurosci. 2005 Aug 10; 25(32):7317-23. View Abstract
232. Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem. 2005 Aug 19; 280(33):29820-7. View Abstract
233. How do adult neurons survive? Discov Med. 2005 Jun; 5(27):309-18. View Abstract
234. Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis. Endocrinology. 2005 Aug; 146(8):3614-21. View Abstract
235. Pain TRPs. Neuron. 2005 Apr 07; 46(1):9-12. View Abstract
236. ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Pain. 2005 Mar; 114(1-2):149-59. View Abstract
237. DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem. 2005 Apr 08; 280(14):14122-9. View Abstract
238. Patients with chest pain and occult gastroesophageal reflux demonstrate visceral pain hypersensitivity which may be partially responsive to acid suppression. Am J Gastroenterol. 2004 Oct; 99(10):1998-2006. View Abstract
239. Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. J Neurosci. 2004 Sep 22; 24(38):8310-21. View Abstract
240. Adult neuron survival strategies--slamming on the brakes. Nat Rev Neurosci. 2004 Sep; 5(9):686-700. View Abstract
241. Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neurons. Eur J Neurosci. 2004 Aug; 20(3):671-83. View Abstract
242. Differential analgesic sensitivity of two distinct neuropathic pain models. Anesth Analg. 2004 Aug; 99(2):457-63, table of contents. View Abstract
243. Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons. Eur J Neurosci. 2004 Jul; 20(2):375-84. View Abstract
244. Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy. Life Sci. 2004 Apr 09; 74(21):2605-10. View Abstract
245. Pain: moving from symptom control toward mechanism-specific pharmacologic management. Ann Intern Med. 2004 Mar 16; 140(6):441-51. View Abstract
246. The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor. Gastroenterology. 2004 Mar; 126(3):683-92. View Abstract
247. Dynamic changes in glypican-1 expression in dorsal root ganglion neurons after peripheral and central axonal injury. Eur J Neurosci. 2004 Mar; 19(5):1119-32. View Abstract
248. DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004 Feb 25; 24(8):2027-36. View Abstract
249. Utilization of an HSV-based amplicon vector encoding the axonal marker hPLAP to follow neurite outgrowth in cultured DRG neurons. J Neurosci Methods. 2004 Jan 30; 132(2):169-76. View Abstract
250. Use and abuse of opioid analgesics: potential methods to prevent and deter non-medical consumption of prescription opioids. Curr Opin Investig Drugs. 2004 Jan; 5(1):61-6. View Abstract
251. Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain. Neuroscience. 2004; 124(4):891-900. View Abstract
252. Central sensitization and LTP: do pain and memory share similar mechanisms? Trends Neurosci. 2003 Dec; 26(12):696-705. View Abstract
253. Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block. Anesthesiology. 2003 Dec; 99(6):1402-8. View Abstract
254. Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn. Mol Cell Neurosci. 2003 Nov; 24(3):818-30. View Abstract
255. Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss. Nat Neurosci. 2003 Nov; 6(11):1186-93. View Abstract
256. High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons. Mol Cell Neurosci. 2003 Sep; 24(1):106-16. View Abstract
257. Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury. Eur J Neurosci. 2003 Aug; 18(4):911-22. View Abstract
258. A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain. J Neurosci. 2003 Jun 15; 23(12):5031-40. View Abstract
259. p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci. 2003 May 15; 23(10):4017-22. View Abstract
260. No Nogo: now where to go? Neuron. 2003 Apr 24; 38(2):153-6. View Abstract
261. Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn. J Physiol. 2003 Apr 01; 548(Pt 1):131-8. View Abstract
262. Exploiting microarrays to reveal differential gene expression in the nervous system. Genome Biol. 2003; 4(2):105. View Abstract
263. The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans. Gastroenterology. 2003 Jan; 124(1):18-25. View Abstract
264. Gabapentin-- actions on adult superficial dorsal horn neurons. Neuropharmacology. 2002 Dec; 43(7):1077-81. View Abstract
265. Can we conquer pain? Nat Neurosci. 2002 Nov; 5 Suppl:1062-7. View Abstract
266. Progressive tactile hypersensitivity after a peripheral nerve crush: non-noxious mechanical stimulus-induced neuropathic pain. Pain. 2002 Nov; 100(1-2):155-62. View Abstract
267. Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci. 2002 Oct 25; 3:16. View Abstract
268. Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival. Neuron. 2002 Sep 26; 36(1):45-56. View Abstract
269. p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron. 2002 Sep 26; 36(1):57-68. View Abstract
270. A single preoperative oral dose of valdecoxib, a new cyclooxygenase-2 specific inhibitor, relieves post-oral surgery or bunionectomy pain. Anesthesiology. 2002 Sep; 97(3):565-73. View Abstract
271. Neuroscience. It takes more than two to Nogo. Science. 2002 Aug 16; 297(5584):1132-4. View Abstract
272. Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets. Trends Mol Med. 2002 Aug; 8(8):390-6. View Abstract
273. Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord. J Neurosci. 2002 Aug 01; 22(15):6724-31. View Abstract
274. The pattern of expression of the voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 does not change in uninjured primary sensory neurons in experimental neuropathic pain models. Pain. 2002 Apr; 96(3):269-277. View Abstract
275. No DREAM, No pain. Closing the spinal gate. Cell. 2002 Feb 08; 108(3):297-300. View Abstract
276. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J Neurosci. 2002 Jan 15; 22(2):478-85. View Abstract
277. Mechanisms of pain and their therapeutic implications. J Am Vet Med Assoc. 2001 Nov 15; 219(10):1346-56. View Abstract
278. Central neural mechanisms mediating human visceral hypersensitivity. Am J Physiol Gastrointest Liver Physiol. 2001 Nov; 281(5):G1196-202. View Abstract
279. Patrick D. Wall (1925-2001). Nature. 2001 Sep 27; 413(6854):378. View Abstract
280. Developmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons. J Neurosci. 2001 Aug 15; 21(16):6077-85. View Abstract
281. The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19; 31(1):59-73. View Abstract
282. A-fiber sensory input induces neuronal cell death in the dorsal horn of the adult rat spinal cord. J Comp Neurol. 2001 Jul 02; 435(3):276-82. View Abstract
283. Mechanism-based pain diagnosis: issues for analgesic drug development. Anesthesiology. 2001 Jul; 95(1):241-9. View Abstract
284. Transport and localization of the DEG/ENaC ion channel BNaC1alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons. J Neurosci. 2001 Apr 15; 21(8):2678-86. View Abstract
285. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 2001 Mar 22; 410(6827):471-5. View Abstract
286. Direct activation of rat spinal dorsal horn neurons by prostaglandin E2. J Neurosci. 2001 Mar 01; 21(5):1750-6. View Abstract
287. Differential gene expression--how to find new analgesic targets. Curr Opin Investig Drugs. 2001 Mar; 2(3):396-8. View Abstract
288. Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain. Neurobiol Dis. 2001 Feb; 8(1):1-10. View Abstract
289. Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2. Physiol Genomics. 2001 Jan 19; 4(3):165-74. View Abstract
290. Turbocharging neurons for growth: accelerating regeneration in the adult CNS. Nat Neurosci. 2001 Jan; 4(1):7-9. View Abstract
291. Changes in tactile stimuli-induced behavior and c-Fos expression in the superficial dorsal horn and in parabrachial nuclei after sciatic nerve crush. J Comp Neurol. 2000 Dec 04; 428(1):45-61. View Abstract
292. Pain. Neurobiol Dis. 2000 Oct; 7(5):504-10. View Abstract
293. Contribution of central sensitisation to the development of non-cardiac chest pain. Lancet. 2000 Sep 30; 356(9236):1154-9. View Abstract
294. Pain mechanisms and management: a central perspective. Clin J Pain. 2000 Sep; 16(3 Suppl):S144-56. View Abstract
295. Pain: molecular mechanisms. J Pain. 2000 Sep; 1(3 Suppl):35-44. View Abstract
296. Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain. 2000 Aug; 87(2):149-158. View Abstract
297. Resection of sciatic nerve re-triggers central sprouting of A-fibre primary afferents in the rat. Neurosci Lett. 2000 Jul 21; 288(3):215-8. View Abstract
298. Delayed loss of small dorsal root ganglion cells after transection of the rat sciatic nerve. J Comp Neurol. 2000 Jun 26; 422(2):172-80. View Abstract
299. Neuronal plasticity: increasing the gain in pain. Science. 2000 Jun 09; 288(5472):1765-9. View Abstract
300. Putting the spinal cord together again. Neuron. 2000 May; 26(2):291-3. View Abstract
301. Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2. Mol Cell Neurosci. 2000 Apr; 15(4):331-42. View Abstract
302. Trigeminal neuralgia: opportunities for research and treatment. Pain. 2000 Mar; 85(1-2):3-7. View Abstract
303. The bigger the better or small but perfectly formed? Pain. 2000 Feb; 84(2-3):445-6. View Abstract
304. Silent NMDA receptor-mediated synapses are developmentally regulated in the dorsal horn of the rat spinal cord. J Neurophysiol. 2000 Feb; 83(2):955-62. View Abstract
305. Synaptic transmission and plasticity in the superficial dorsal horn. Prog Brain Res. 2000; 129:63-80. View Abstract
306. Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci. 1999 Dec; 2(12):1114-9. View Abstract
307. Semaphorin 3A growth cone collapse requires a sequence homologous to tarantula hanatoxin. Proc Natl Acad Sci U S A. 1999 Nov 09; 96(23):13501-5. View Abstract
308. A role for HSP27 in sensory neuron survival. J Neurosci. 1999 Oct 15; 19(20):8945-53. View Abstract
309. Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci U S A. 1999 Aug 03; 96(16):9385-90. View Abstract
310. Implications of recent advances in the understanding of pain pathophysiology for the assessment of pain in patients. Pain. 1999 Aug; Suppl 6:S141-S147. View Abstract
311. Axonal regeneration from injured dorsal roots into the spinal cord of adult rats. J Comp Neurol. 1999 Jul 19; 410(1):42-54. View Abstract
312. Transcriptional and posttranslational plasticity and the generation of inflammatory pain. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):7723-30. View Abstract
313. Pain. Curr Biol. 1999 Jun 17; 9(12):R429-31. View Abstract
314. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet. 1999 Jun 05; 353(9168):1959-64. View Abstract
315. Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron. 1999 May; 23(1):83-91. View Abstract
316. Peripheral inflammation facilitates Abeta fiber-mediated synaptic input to the substantia gelatinosa of the adult rat spinal cord. J Neurosci. 1999 Jan 15; 19(2):859-67. View Abstract
317. Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner. Neuroscience. 1999; 91(4):1425-33. View Abstract
318. Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons. Nat Neurosci. 1998 Dec; 1(8):653-5. View Abstract
319. Recovery of C-fiber-induced extravasation following peripheral nerve injury in the rat. Exp Neurol. 1998 Dec; 154(2):628-36. View Abstract
320. Towards a mechanism-based classification of pain? Pain. 1998 Sep; 77(3):227-229. View Abstract
321. High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5. Gene Ther. 1998 Aug; 5(8):1137-47. View Abstract
322. Heat shock protein 27: developmental regulation and expression after peripheral nerve injury. J Neurosci. 1998 Aug 01; 18(15):5891-900. View Abstract
323. Leukemia inhibitory factor is an anti-inflammatory and analgesic cytokine. J Neurosci. 1998 Jul 15; 18(14):5456-62. View Abstract
324. Identification of somatostatin sst2(a) receptor expressing neurones in central regions involved in nociception. Brain Res. 1998 Jul 06; 798(1-2):25-35. View Abstract
325. Morphine, the NMDA receptor antagonist MK801 and the tachykinin NK1 receptor antagonist RP67580 attenuate the development of inflammation-induced progressive tactile hypersensitivity. Pain. 1998 Jul; 77(1):49-57. View Abstract
326. Null mutations lacking substance: elucidating pain mechanisms by genetic pharmacology. Neuron. 1998 Jun; 20(6):1063-6. View Abstract
327. Deafferentation is insufficient to induce sprouting of A-fibre central terminals in the rat dorsal horn. J Comp Neurol. 1998 Apr 06; 393(2):135-44. View Abstract
328. Growth-associated protein 43 immunoreactivity in the superficial dorsal horn of the rat spinal cord is localized in atrophic C-fiber, and not in sprouted A-fiber, central terminals after peripheral nerve injury. J Comp Neurol. 1997 Sep 15; 386(1):111-8. View Abstract
329. Cytokines, nerve growth factor and inflammatory hyperalgesia: the contribution of tumour necrosis factor alpha. Br J Pharmacol. 1997 Jun; 121(3):417-24. View Abstract
330. Central changes in primary afferent fibers following peripheral nerve lesions. Neuroscience. 1997 Apr; 77(4):1115-22. View Abstract
331. Intact sciatic myelinated primary afferent terminals collaterally sprout in the adult rat dorsal horn following section of a neighbouring peripheral nerve. J Comp Neurol. 1997 Mar 31; 380(1):95-104. View Abstract
332. Tachykinin NK1 receptor antagonist RP67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats. Eur J Pharmacol. 1997 Mar 19; 322(2-3):165-71. View Abstract
333. The progressive tactile hyperalgesia induced by peripheral inflammation is nerve growth factor dependent. Neuroreport. 1997 Mar 03; 8(4):807-10. View Abstract
334. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature. 1996 Nov 28; 384(6607):360-4. View Abstract
335. Basal and touch-evoked fos-like immunoreactivity during experimental inflammation in the rat. Pain. 1996 Oct; 67(2-3):307-16. View Abstract
336. Glutamate-mediated slow synaptic currents in neonatal rat deep dorsal horn neurons in vitro. J Neurophysiol. 1996 Sep; 76(3):1465-76. View Abstract
337. Progressive tactile hypersensitivity: an inflammation-induced incremental increase in the excitability of the spinal cord. Pain. 1996 Sep; 67(1):97-106. View Abstract
338. Collateral sprouting of uninjured primary afferent A-fibers into the superficial dorsal horn of the adult rat spinal cord after topical capsaicin treatment to the sciatic nerve. J Neurosci. 1996 Aug 15; 16(16):5189-95. View Abstract
339. Windup and central sensitization are not equivalent. Pain. 1996 Aug; 66(2-3):105-8. View Abstract
340. Expression of a developmentally regulated, phosphorylated isoform of microtubule-associated protein 1B in regenerating axons of the sciatic nerve. Neuroscience. 1996 Jul; 73(2):553-63. View Abstract
341. Intrinsic versus extrinsic factors in determining the regeneration of the central processes of rat dorsal root ganglion neurons: the influence of a peripheral nerve graft. J Comp Neurol. 1996 Jun 17; 370(1):97-104. View Abstract
342. Zinc reduces the hyperalgesia and upregulation of NGF and IL-1 beta produced by peripheral inflammation in the rat. Neuropharmacology. 1996 May; 35(5):599-603. View Abstract
343. Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation. J Neurosci. 1996 Apr 15; 16(8):2716-23. View Abstract
344. Phenotypic modification of primary sensory neurons: the role of nerve growth factor in the production of persistent pain. Philos Trans R Soc Lond B Biol Sci. 1996 Mar 29; 351(1338):441-8. View Abstract
345. Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent. Neurosci Lett. 1996 Feb 02; 204(1-2):29-32. View Abstract
346. Influence of inflammation or disconnection from peripheral target tissue on the capsaicin sensitivity of rat dorsal root ganglion sensory neurones. Neurosci Lett. 1996 Jan 19; 203(2):119-22. View Abstract
347. Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-D-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics. Pain. 1996 Jan; 64(1):59-70. View Abstract
348. Spinal injury. Overcoming inhibition. Nature. 1995 Nov 30; 378(6556):439-40. View Abstract
349. Reorganization of central terminals of myelinated primary afferents in the rat dorsal horn following peripheral axotomy. J Comp Neurol. 1995 Sep 11; 360(1):121-34. View Abstract
350. Involvement of neurokinin receptors in the induction but not the maintenance of mechanical allodynia in rat flexor motoneurones. J Physiol. 1995 Aug 01; 486 ( Pt 3):769-77. View Abstract
351. Somatic pain--pathogenesis and prevention. Br J Anaesth. 1995 Aug; 75(2):169-76. View Abstract
352. Contribution of interleukin-1 beta to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol. 1995 Aug; 115(7):1265-75. View Abstract
353. Nerve growth factor contributes to the up-regulation of growth-associated protein 43 and preprotachykinin A messenger RNAs in primary sensory neurons following peripheral inflammation. Neuroscience. 1995 Aug; 67(3):753-61. View Abstract
354. An overview of the mechanisms of hyperalgesia. Pulm Pharmacol. 1995 Aug-Oct; 8(4-5):161-7. View Abstract
355. Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia. Pain. 1995 Jun; 61(3):383-390. View Abstract
356. Is there any clinical advantage of increasing the pre-emptive dose of morphine or combining pre-incisional with postoperative morphine administration? Br J Anaesth. 1995 Apr; 74(4):396-9. View Abstract
357. Pre-emptive analgesia. Anaesthesia. 1995 Feb; 50(2):176-7. View Abstract
358. Morphine selectively depresses the slowest, NMDA-independent component of C-fibre-evoked synaptic activity in the rat spinal cord in vitro. Eur J Neurosci. 1995 Jan 01; 7(1):12-8. View Abstract
359. Neurite outgrowth and GAP-43 mRNA expression in cultured adult rat dorsal root ganglion neurons: effects of NGF or prior peripheral axotomy. J Neurosci Res. 1994 Dec 15; 39(6):634-45. View Abstract
360. Nerve growth factor levels in developing rat skin: upregulation following skin wounding. Neuroreport. 1994 Nov 21; 5(17):2281-4. View Abstract
361. NK1 and NK2 receptors contribute to C-fibre evoked slow potentials in the spinal cord. Neuroreport. 1994 Oct 27; 5(16):2105-8. View Abstract
362. The downregulation of GAP-43 is not responsible for the failure of regeneration in freeze-killed nerve grafts in the rat. Exp Neurol. 1994 Oct; 129(2):311-20. View Abstract
363. Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience. 1994 Sep; 62(2):327-31. View Abstract
364. The pathophysiology of chronic pain--increased sensitivity to low threshold A beta-fibre inputs. Curr Opin Neurobiol. 1994 Aug; 4(4):525-34. View Abstract
365. Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation. Pain. 1994 Aug; 58(2):141-155. View Abstract
366. The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord. J Neurophysiol. 1994 Jul; 72(1):169-79. View Abstract
367. GAP-43 expression in primary sensory neurons following central axotomy. J Neurosci. 1994 Jul; 14(7):4375-84. View Abstract
368. Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: morphology and distribution. J Comp Neurol. 1994 Jun 15; 344(3):321-35. View Abstract
369. A new strategy for the treatment of inflammatory pain. Prevention or elimination of central sensitization. Drugs. 1994; 47 Suppl 5:1-9; discussion 46-7. View Abstract
370. Partial denervation of the medial gastrocnemius muscle results in growth-associated protein-43 immunoreactivity in sprouting axons and Schwann cells. Neuroscience. 1993 Nov; 57(2):433-42. View Abstract
371. Reciprocal Schwann cell-axon interactions. Curr Opin Neurobiol. 1993 Oct; 3(5):683-93. View Abstract
372. Cobalt uptake enables identification of capsaicin- and bradykinin-sensitive subpopulations of rat dorsal root ganglion cells in vitro. Neuroscience. 1993 Sep; 56(1):241-6. View Abstract
373. Preemptive analgesia--treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg. 1993 Aug; 77(2):362-79. View Abstract
374. Preoperative morphine pre-empts postoperative pain. Lancet. 1993 Jul 10; 342(8863):73-5. View Abstract
375. Small-caliber afferent inputs produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A-fibers in the neonatal rat spinal cord in vitro. J Neurophysiol. 1993 Jun; 69(6):2116-28. View Abstract
376. Rate of rise of the cumulative depolarization evoked by repetitive stimulation of small-caliber afferents is a predictor of action potential windup in rat spinal neurons in vitro. J Neurophysiol. 1993 May; 69(5):1621-31. View Abstract
377. Morphological and membrane properties of young rat lumbar and thoracic dorsal root ganglion cells with unmyelinated axons. Brain Res. 1993 Apr 23; 609(1-2):193-200. View Abstract
378. Chronic peripheral nerve section results in a rearrangement of the central axonal arborizations of axotomized A beta primary afferent neurons in the rat spinal cord. J Comp Neurol. 1993 Apr 01; 330(1):65-82. View Abstract
379. Morphology and somatotopy of the central arborizations of rapidly adapting glabrous skin afferents in the rat lumbar spinal cord. J Comp Neurol. 1993 Mar 22; 329(4):491-511. View Abstract
380. The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro. Neuroscience. 1993 Feb; 52(4):1029-37. View Abstract
381. The pathophysiology of peripheral neuropathic pain--abnormal peripheral input and abnormal central processing. Acta Neurochir Suppl (Wien). 1993; 58:125-30. View Abstract
382. Factors controlling the expression of GAP-43 in dorsal root ganglia cells: implications for plasticity and growth of central terminals. Restor Neurol Neurosci. 1993 Jan 01; 5(1):51-2. View Abstract
383. Long duration ventral root potentials in the neonatal rat spinal cord in vitro; the effects of ionotropic and metabotropic excitatory amino acid receptor antagonists. Brain Res. 1992 Nov 06; 595(1):87-97. View Abstract
384. Neurotoxic damage evokes regenerative responses from adult rat sensory neurones. Neurosci Lett. 1992 Oct 26; 146(1):48-52. View Abstract
385. Denervation of the motor endplate results in the rapid expression by terminal Schwann cells of the growth-associated protein GAP-43. J Neurosci. 1992 Oct; 12(10):3999-4010. View Abstract
386. Regional differences in the distribution of capsaicin-sensitive target-identified adult rat dorsal root ganglion neurons. Neurosci Lett. 1992 Aug 31; 143(1-2):251-4. View Abstract
387. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature. 1992 Jan 02; 355(6355):75-8. View Abstract
388. Terminal Schwann cells elaborate extensive processes following denervation of the motor endplate. J Neurocytol. 1992 Jan; 21(1):50-66. View Abstract
389. GAP-43 mRNA in Rat Spinal Cord and Dorsal Root Ganglia Neurons: Developmental Changes and Re-expression Following Peripheral Nerve Injury. Eur J Neurosci. 1992; 4(10):883-95. View Abstract
390. Distribution of the growth associated protein GAP-43 in the central processes of axotomized primary afferents in the adult rat spinal cord; presence of growth cone-like structures. Neurosci Lett. 1991 Sep 30; 131(1):37-41. View Abstract
391. Generation of acute pain: central mechanisms. Br Med Bull. 1991 Jul; 47(3):523-33. View Abstract
392. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states. Pain. 1991 Mar; 44(3):293-299. View Abstract
393. Common patterns of plasticity contributing to nociceptive sensitization in mammals and Aplysia. Trends Neurosci. 1991 Feb; 14(2):74-8. View Abstract
394. Time-dependent differences in the increase in GAP-43 expression in dorsal root ganglion cells after peripheral axotomy. Neuroscience. 1991; 45(1):213-20. View Abstract
395. Collateral sprouting of the central terminals of cutaneous primary afferent neurons in the rat spinal cord: pattern, morphology, and influence of targets. J Comp Neurol. 1990 Oct 15; 300(3):370-85. View Abstract
396. Characterization of the cutaneous input to the ventral horn in vitro using the isolated spinal cord-hind limb preparation. J Neurosci Methods. 1990 Oct; 35(1):39-46. View Abstract
397. Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord. J Neurosci. 1990 Aug; 10(8):2717-26. View Abstract
398. Neonatal capsaicin treatment induces invasion of the substantia gelatinosa by the terminal arborizations of hair follicle afferents in the rat dorsal horn. J Comp Neurol. 1990 Jun 01; 296(1):23-31. View Abstract
399. The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. Neuroscience. 1990; 34(2):465-78. View Abstract
400. Activity-Dependent Changes in Rat Ventral Horn Neurons in vitro; Summation of Prolonged Afferent Evoked Postsynaptic Depolarizations Produce a d-2-Amino-5-Phosphonovaleric Acid Sensitive Windup. Eur J Neurosci. 1990; 2(7):638-49. View Abstract
401. Morphology and somatotopic organization of the central terminals of hindlimb hair follicle afferents in the rat lumbar spinal cord. J Comp Neurol. 1989 Nov 15; 289(3):416-33. View Abstract
402. Subthreshold components of the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat lumbar spinal cord. J Neurophysiol. 1989 Oct; 62(4):907-16. View Abstract
403. Recent advances in the pathophysiology of acute pain. Br J Anaesth. 1989 Aug; 63(2):139-46. View Abstract
404. Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint. Neuroscience. 1989; 32(2):493-502. View Abstract
405. Sensory innervation of the hairs of the rat hindlimb: a light microscopic analysis. J Comp Neurol. 1988 Nov 08; 277(2):183-94. View Abstract
406. The responses recorded in vitro of deep dorsal horn neurons to direct and orthodromic stimulation in the young rat spinal cord. Neuroscience. 1988 Oct; 27(1):231-42. View Abstract
407. An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice. Neurosci Lett. 1988 Jul 08; 89(3):286-92. View Abstract
408. Prolonged primary afferent induced alterations in dorsal horn neurones, an intracellular analysis in vivo and in vitro. J Physiol (Paris). 1988-1989; 83(3):255-66. View Abstract
409. Physiology and morphology of multireceptive neurons with C-afferent fiber inputs in the deep dorsal horn of the rat lumbar spinal cord. J Neurophysiol. 1987 Sep; 58(3):460-79. View Abstract
410. The postnatal development of the ventral root reflex in the rat; a comparative in vivo and in vitro study. Neurosci Lett. 1987 Jul 09; 78(1):41-5. View Abstract
411. Central terminations of cutaneous mechanoreceptive afferents in the rat lumbar spinal cord. J Comp Neurol. 1987 Jul 01; 261(1):105-19. View Abstract
412. Excitatory amino acids increase glycogen phosphorylase activity in the rat spinal cord. Neurosci Lett. 1987 Jan 27; 73(3):209-14. View Abstract
413. Physiological, inflammatory and neuropathic pain. Adv Tech Stand Neurosurg. 1987; 15:39-62. View Abstract
414. Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input. Nature. 1987 Jan 8-14; 325(7000):151-3. View Abstract
415. Prolonged C-fibre mediated facilitation of the flexion reflex in the rat is not due to changes in afferent terminal or motoneurone excitability. Neurosci Lett. 1986 Sep 25; 70(1):91-6. View Abstract
416. Somatotopic organization of cutaneous afferent terminals and dorsal horn neuronal receptive fields in the superficial and deep laminae of the rat lumbar spinal cord. J Comp Neurol. 1986 Sep 22; 251(4):517-31. View Abstract
417. Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat. Neurosci Lett. 1986 May 15; 66(2):226-30. View Abstract
418. Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat. J Neurosci. 1986 May; 6(5):1433-42. View Abstract
419. The brief and the prolonged facilitatory effects of unmyelinated afferent input on the rat spinal cord are independently influenced by peripheral nerve section. Neuroscience. 1986 Apr; 17(4):1199-205. View Abstract
420. Morphine-sensitive and morphine-insensitive actions of C-fibre input on the rat spinal cord. Neurosci Lett. 1986 Feb 28; 64(2):221-5. View Abstract
421. The systemic administration of local anaesthetics produces a selective depression of C-afferent fibre evoked activity in the spinal cord. Pain. 1985 Dec; 23(4):361-374. View Abstract
422. Injury-induced plasticity of the flexor reflex in chronic decerebrate rats. Neuroscience. 1985 Oct; 16(2):395-404. View Abstract
423. Cutaneous receptive field and morphological properties of hamstring flexor alpha-motoneurones in the rat. J Physiol. 1985 Jul; 364:249-63. View Abstract
424. Mapping increased glycogen phosphorylase activity in dorsal root ganglia and in the spinal cord following peripheral stimuli. J Comp Neurol. 1985 Apr 01; 234(1):60-76. View Abstract
425. The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord. J Comp Neurol. 1985 Jan 01; 231(1):66-77. View Abstract
426. Neurogenic extravasation and substance P levels are low in muscle as compared to skin the rat hindlimb. Neurosci Lett. 1984 Dec 21; 52(3):235-40. View Abstract
427. Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat. J Physiol. 1984 Nov; 356:443-58. View Abstract
428. Axotomy increases glycogen phosphorylase activity in motoneurones. Neuroscience. 1984 Aug; 12(4):1261-9. View Abstract
429. The cutaneous contribution to the hamstring flexor reflex in the rat: an electrophysiological and anatomical study. Brain Res. 1984 Jun 15; 303(2):299-312. View Abstract
430. Long term alterations in the excitability of the flexion reflex produced by peripheral tissue injury in the chronic decerebrate rat. Pain. 1984 Apr; 18(4):325-343. View Abstract
431. A selective effect of naloxone on heterosynaptic C-fibre-mediated inhibitions in the rat dorsal horn. Neurosci Lett. 1984 Mar 23; 45(2):169-74. View Abstract
432. Alterations in the structure, function, and chemistry of C fibers following local application of vinblastine to the sciatic nerve of the rat. J Neurosci. 1984 Feb; 4(2):430-41. View Abstract
433. The properties of neurones recorded in the superficial dorsal horn of the rat spinal cord. J Comp Neurol. 1983 Dec 10; 221(3):313-28. View Abstract
434. Evidence for a central component of post-injury pain hypersensitivity. Nature. 1983 Dec 15-21; 306(5944):686-8. View Abstract
435. Endogenous opioid peptides and pain mechanisms: a complex relationship. Nature. 1983 Dec 22-1984 Jan 4; 306(5945):739-40. View Abstract
436. C-primary afferent fibre mediated inhibitions in the dorsal horn of the decerebrate-spinal rat. Exp Brain Res. 1983; 51(2):283-90. View Abstract
437. Effects of capsaicin on receptive fields and on inhibitions in rat spinal cord. Exp Neurol. 1982 Nov; 78(2):425-36. View Abstract
438. Chronic peripheral nerve section diminishes the primary afferent A-fibre mediated inhibition of rat dorsal horn neurones. Brain Res. 1982 Jun 17; 242(1):77-85. View Abstract
439. Do opioid peptides mediate a presynaptic control of C-fibre transmission in the rat spinal cord? Neurosci Lett. 1982 Mar 17; 29(1):67-72. View Abstract
440. The time course and specificity of the changes in the behavioural and dorsal horn cell responses to noxious stimuli following peripheral nerve capsaicin treatment in the rat. Neuroscience. 1982; 7(9):2051-6. View Abstract
441. Effects of cutaneous nerve and intraspinal conditioning of C-fibre afferent terminal excitability in decerebrate spinal rats. J Physiol. 1981 Sep; 318:25-39. View Abstract
442. Lamina-specific alteration of C-fibre evoked activity by morphine in the dorsal horn of the rat spinal cord. Neurosci Lett. 1981 Aug 07; 25(1):37-41. View Abstract
443. Tooth pulp input to the spinal trigeminal nucleus: a comparison of inhibitions following segmental and raphe magnus stimulation. Brain Res. 1981 Jun 09; 214(1):73-87. View Abstract
444. Inhibitory controls on thermal neurones in the spinal trigeminal nucleus of cats and rats. Brain Res. 1981 Mar 30; 209(2):440-5. View Abstract
445. Intrathecal high dose morphine produces hyperalgesia in the rat. Brain Res. 1981 Mar 30; 209(2):491-5. View Abstract
446. The effect of intracerebroventricular injections of morphine on vasopressin release in the rat. J Physiol. 1981 Feb; 311:401-9. View Abstract
447. The stereospecific effect of naloxone on rat dorsal horn neurones; inhibition in superficial laminae and excitation in deeper laminae. Pain. 1980 Dec; 9(3):293-306. View Abstract
448. What we don't know about pain. Nature. 1980 Sep 18; 287(5779):185-6. View Abstract
449. Intracerebral naloxone and the reaction to thermal noxious stimulation in the rat. Brain Res. 1980 May 26; 190(2):578-83. View Abstract
450. Analgesia and hyperalgesia produced in the rat by intrathecal naloxone. Brain Res. 1980 May 12; 189(2):593-7. View Abstract
451. Antinociceptive effect of peripheral segmental electrical stimulation in the rat. Pain. 1980 Apr; 8(2):237-252. View Abstract
452. The site of action of corticosteroid antipyresis in the rabbit. J Physiol. 1980 Mar; 300:1-6. View Abstract
453. Transcutaneous electrical nerve stimulation and the reaction to experimental pain in human subjects. Pain. 1979 Oct; 7(2):115-127. View Abstract
454. Descending tryptaminergic pathways and the antinociceptive effect produced by peripheral electrical stimulation in the rat [proceedings]. J Physiol. 1979 Aug; 293:59P-60P. View Abstract
455. Gliding edge dislocations in proteins as a mechanism for active ion transport. Biochem J. 1978 Mar 01; 169(3):559-65. View Abstract
456. Failure of naloxone to reverse peripheral transcutaneous electro-analgesia in patients suffering from acute trauma. S Afr Med J. 1978 Feb 04; 53(5):179-80. View Abstract
457. Naloxone-reversible peripheral electroanalgesia in intact and spinal rats. Eur J Pharmacol. 1977 Oct 01; 45(3):311-4. View Abstract
458. Management of acute traumatic pain by peripheral transcutaneous electrical stimulation. S Afr Med J. 1977 Aug 13; 52(8):309-12. View Abstract
459. A dissociation between temperature regulation and fever in the rabbit. J Physiol. 1977 Apr; 266(2):423-33. View Abstract
460. The effect of an inhibitor of adenylate cyclase on the development of pyrogen, prostaglandin and cyclic AMP fevers in the rabbit. Pflugers Arch. 1976 Dec 28; 367(2):177-81. View Abstract
461. Does cyclic AMP have a role in the pathogenesis of fever in the rabbit? Naturwissenschaften. 1976 Feb; 63(2):94-5. View Abstract
462. The effect of sodium salicylate on dibutyryl cyclic AMP fever in the conscious rabbit. Neuropharmacology. 1976 Jan; 15(1):9-10. View Abstract
463. Pyrogen and prostaglandin fever in the rabbit-II: Effects of noradrenaline depletion and adrenergic receptor blockade. Neuropharmacology. 1975 May-Jun; 14(5-6):405-11. View Abstract
464. Pyrogen and prostaglandin fever in the rabbit-I: Effects of salicylate and the role of cyclic AMP. Neuropharmacology. 1975 May-Jun; 14(5-6):397-403. View Abstract
465. Hypothalamic heating and cooling in monoamine-depleted rabbits. Am J Physiol. 1975 Feb; 228(2):569-74. View Abstract
466. Time dependence of a neurochemical correlate of a learning task: a non-disruptive approach to memory consolidation. Experientia. 1974 Jul 15; 30(7):760-2. View Abstract
467. Proceedings: A role for noradrenaline and cyclic AMP in prostaglandin E1 Fever. J Physiol. 1974 Jul; 240(2):49P-50P. View Abstract
468. Alterations in the mechanical properties of the lung during dyspnea in chronic obstructive pulmonary disease. J Clin Invest. 1970 Apr; 49(4):747-51. View Abstract
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