Research Overview

Dr. McAdam's research focuses on the utility of diagnostic tests for infections of children.

Education

Medical School

University of Rochester
1995 Rochester NY

Internship

Brigham & Women's Hospital
1996 Boston MA

Residency

Clinical Pathology Brigham & Women's Hospital
1998 Boston MA

Publications

  1. 2023 Acknowledgment of JCM Reviewers. J Clin Microbiol. 2024 May 08; 62(5):e0055424. View Abstract
  2. De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen. bioRxiv. 2024 Feb 06. View Abstract
  3. "Innovative Diagnostic Methods," a new section in the Journal of Clinical Microbiology. J Clin Microbiol. 2024 01 17; 62(1):e0141723. View Abstract
  4. The Editors' reply to "Letter responding to performance of updated Enterobacterales piperacillin-tazobactam breakpoints on the MicroScan antimicrobial susceptibility testing system". J Clin Microbiol. 2023 11 21; 61(11):e0069223. View Abstract
  5. Antibiotic Therapy for Culture-Proven Bacterial Overgrowth in Children With Intestinal Failure Results in Improved Symptoms and Growth. J Pediatr Gastroenterol Nutr. 2022 09 01; 75(3):345-350. View Abstract
  6. Clinical Laboratory Budgets during the COVID-19 Pandemic: a Micro-Comic Strip. J Clin Microbiol. 2022 03 16; 60(3):e0009622. View Abstract
  7. Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. Nat Commun. 2022 03 09; 13(1):1231. View Abstract
  8. Cycle Threshold Values from Severe Acute Respiratory Syndrome Coronavirus-2 Reverse Transcription-Polymerase Chain Reaction Assays: Interpretation and Potential Use Cases. Clin Lab Med. 2022 06; 42(2):237-248. View Abstract
  9. Biographical Feature: Andrew B. Onderdonk, Ph.D. J Clin Microbiol. 2021 10 19; 59(11):e0150521. View Abstract
  10. Predictive Value of Direct Disk Diffusion Testing from Positive Blood Cultures in a Children's Hospital and Its Utility in Antimicrobial Stewardship. J Clin Microbiol. 2021 05 19; 59(6). View Abstract
  11. Fun Classifying Fungal Infections: a Micro-Comic Strip. J Clin Microbiol. 2021 04 20; 59(5). View Abstract
  12. Too Slow, Less Dough for SARS-CoV-2 Tests? A Micro-Comic Strip. J Clin Microbiol. 2021 01 21; 59(2). View Abstract
  13. Practice Improvement for Standardized Evaluation and Management of Acute Tracheitis in Mechanically Ventilated Children. Pediatr Qual Saf. 2021 Jan-Feb; 6(1):e368. View Abstract
  14. Can We Test Our Way Out of the COVID-19 Pandemic? J Clin Microbiol. 2020 10 21; 58(11). View Abstract
  15. The ASM Journals Committee Values the Contributions of Black Microbiologists. J Virol. 2020 09 29; 94(20). View Abstract
  16. The ASM Journals Committee Values the Contributions of Black Microbiologists. J Clin Microbiol. 2020 09 22; 58(10). View Abstract
  17. The ASM Journals Committee Values the Contributions of Black Microbiologists. Antimicrob Agents Chemother. 2020 09 21; 64(10). View Abstract
  18. The ASM Journals Committee Values the Contributions of Black Microbiologists. Infect Immun. 2020 09 18; 88(10). View Abstract
  19. The ASM Journals Committee Values the Contributions of Black Microbiologists. Mol Cell Biol. 2020 09 14; 40(19). View Abstract
  20. The ASM Journals Committee Values the Contributions of Black Microbiologists. J Bacteriol. 2020 09 08; 202(19). View Abstract
  21. The ASM Journals Committee Values the Contributions of Black Microbiologists. Appl Environ Microbiol. 2020 09 01; 86(18). View Abstract
  22. Is This a Critical Result? A Micro-Comic Strip. J Clin Microbiol. 2020 08 24; 58(9). View Abstract
  23. The ASM Journals Committee Values the Contributions of Black Microbiologists. Microbiol Resour Announc. 2020 Jul 31; 9(32). View Abstract
  24. The ASM Journals Committee Values the Contributions of Black Microbiologists. J Microbiol Biol Educ. 2020; 21(2). View Abstract
  25. The ASM Journals Committee Values the Contributions of Black Microbiologists. mSphere. 2020 07 31; 5(4). View Abstract
  26. The ASM Journals Committee Values the Contributions of Black Microbiologists. mSystems. 2020 Jul 31; 5(4). View Abstract
  27. The ASM Journals Committee Values the Contributions of Black Microbiologists. mBio. 2020 07 31; 11(4). View Abstract
  28. The ASM Journals Committee Values the Contributions of Black Microbiologists. Microbiol Mol Biol Rev. 2020 08 19; 84(3). View Abstract
  29. The ASM Journals Committee Values the Contributions of Black Microbiologists. Clin Microbiol Rev. 2020 09 16; 33(4). View Abstract
  30. What Is Needed for the Response to COVID-19? A Micro-Comic Strip. J Clin Microbiol. 2020 Jul 23; 58(8). View Abstract
  31. Special Issue on Diagnostic Testing for Severe Acute Respiratory Syndrome Coronavirus 2 and Lessons from This Pandemic. J Clin Microbiol. 2020 Jul 23; 58(8). View Abstract
  32. The ASM Journals Committee Values the Contributions of Black Microbiologists. Microbiol Spectr. 2020 07; 8(3). View Abstract
  33. Practical guide for pediatric pulmonologists on imaging management of pediatric patients with COVID-19. Pediatr Pulmonol. 2020 09; 55(9):2213-2224. View Abstract
  34. The Clinical Microbiology Laboratory Response to COVID-19: a Micro-Comic Strip. J Clin Microbiol. 2020 05 26; 58(6). View Abstract
  35. What's Special about Cefiderocol? A Micro-Comic Strip. J Clin Microbiol. 2020 04 23; 58(5). View Abstract
  36. The End of Coagulase-Negative Staphylococci? A Micro-Comic Strip. J Clin Microbiol. 2020 02 24; 58(3). View Abstract
  37. The genome of opportunistic fungal pathogen Fusarium oxysporum carries a unique set of lineage-specific chromosomes. Commun Biol. 2020 01 31; 3(1):50. View Abstract
  38. Enterobacteriaceae? Enterobacterales? What Should We Call Enteric Gram-Negative Bacilli? A Micro-Comic Strip. J Clin Microbiol. 2020 01 28; 58(2). View Abstract
  39. Are Bacteria Sensitive or Susceptible? A Micro-Comic Strip. J Clin Microbiol. 2019 12 23; 58(1). View Abstract
  40. Don't Test Me: a Micro-Comic Strip. J Clin Microbiol. 2019 12; 57(12). View Abstract
  41. Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients. Nat Med. 2019 11; 25(11):1728-1732. View Abstract
  42. What's That Species? A Micro-Comic Strip. J Clin Microbiol. 2019 11; 57(11). View Abstract
  43. Total Laboratory Automation: a Micro-Comic Strip. J Clin Microbiol. 2019 10; 57(10). View Abstract
  44. What about Serology? A Micro-Comic Strip. J Clin Microbiol. 2019 09; 57(9). View Abstract
  45. Reply to Molitor, "Susceptibility Categories Should Be Agreed Upon". J Clin Microbiol. 2019 09; 57(9). View Abstract
  46. The Photo Quiz: a Look Back and a Look Forward. J Clin Microbiol. 2019 09; 57(9). View Abstract
  47. Improving the Laboratory Information System: a Micro-Comic Strip. J Clin Microbiol. 2019 08; 57(8). View Abstract
  48. Can You Speciate This for Me? A Micro-Comic Strip. J Clin Microbiol. 2019 07; 57(7). View Abstract
  49. What Is the Future of Clinical Microbiology? Clin Lab Med. 2019 09; 39(3):509-512. View Abstract
  50. Epidemiological Cutoff Values: a Micro-Comic Strip. J Clin Microbiol. 2019 06; 57(6). View Abstract
  51. Biographical Feature: Stephen G. Jenkins, Ph.D., D(ABMM), F(AAM). J Clin Microbiol. 2019 05; 57(5). View Abstract
  52. The Significance of Microbial Taxonomy: a Micro-Comic Strip. J Clin Microbiol. 2019 05; 57(5). View Abstract
  53. The Divergent Meanings of "I" for the Clinical and Laboratory Standards Institute and the European Committee on Antimicrobial Susceptibility Testing: a Micro-Comic Strip. J Clin Microbiol. 2019 04; 57(4). View Abstract
  54. Whole-Genome Sequences of Staphylococcus aureus Isolates from Cystic Fibrosis Lung Infections. Microbiol Resour Announc. 2019 Jan; 8(3). View Abstract
  55. Rebranding Clinical Laboratories: a Micro-Comic Strip. J Clin Microbiol. 2019 01; 57(1). View Abstract
  56. Pitfalls in Performing Research in the Clinical Microbiology Laboratory: a Micro-Comic Strip. J Clin Microbiol. 2018 10; 56(10). View Abstract
  57. Shotgun Metagenomic Detection of Pathogens: a Micro-Comic Strip. J Clin Microbiol. 2018 08; 56(8). View Abstract
  58. Winners of the American Society for Microbiology Awards in Clinical Microbiology. J Clin Microbiol. 2018 06; 56(6). View Abstract
  59. Paying for Point-of-Care Nucleic Acid Amplification Tests: a Micro-Comic Strip. J Clin Microbiol. 2018 06; 56(6). View Abstract
  60. Total Laboratory Automation in Clinical Microbiology: a Micro-Comic Strip. J Clin Microbiol. 2018 04; 56(4). View Abstract
  61. The Utility of Multiplex Molecular Tests for Enteric Pathogens: a Micro-Comic Strip. J Clin Microbiol. 2018 02; 56(2). View Abstract
  62. The Role of Scientific and Medical Societies in Journals … and More: a Micro-Comic Strip. J Clin Microbiol. 2017 12; 55(12):3315. View Abstract
  63. Ceftaroline pharmacokinetics and pharmacodynamics in patients with cystic fibrosis. J Cyst Fibros. 2018 05; 17(3):e25-e31. View Abstract
  64. Sensitivity and Specificity or Positive and Negative Percent Agreement? A Micro-Comic Strip. J Clin Microbiol. 2017 11; 55(11):3153-3154. View Abstract
  65. Discrepant Analysis and Bias: a Micro-Comic Strip. J Clin Microbiol. 2017 10; 55(10):2878-2879. View Abstract
  66. Prevalence and Predictive Values: a Micro-Comic Strip. J Clin Microbiol. 2017 09; 55(9):2566. View Abstract
  67. Reducing Contamination of Blood Cultures: Consider Costs and Clinical Benefits. Clin Infect Dis. 2017 07 15; 65(2):206-207. View Abstract
  68. Unforeseen Consequences: Culture-Independent Diagnostic Tests and Epidemiologic Tracking of Foodborne Pathogens. J Clin Microbiol. 2017 07; 55(7):1978-1979. View Abstract
  69. Global and local selection acting on the pathogen Stenotrophomonas maltophilia in the human lung. Nat Commun. 2017 01 19; 8:14078. View Abstract
  70. A Rose by Any Other Name: Practical Updates on Microbial Nomenclature for Clinical Microbiology. J Clin Microbiol. 2017 01; 55(1):3-4. View Abstract
  71. Association Between Storage Interval and Contamination of Reprocessed Flexible Endoscopes in a Pediatric Gastrointestinal Procedural Unit. Infect Control Hosp Epidemiol. 2017 02; 38(2):131-135. View Abstract
  72. ASM Journals Eliminate Impact Factor Information from Journal Websites. Clin Microbiol Rev. 2016 10; 29(4):i-ii. View Abstract
  73. ASM Journals Eliminate Impact Factor Information from Journal Websites. Appl Environ Microbiol. 2016 09 15; 82(18):5479-80. View Abstract
  74. The Focus on Quality Publications in Journal of Clinical Microbiology. J Clin Microbiol. 2016 09; 54(9):2218. View Abstract
  75. ASM Journals Eliminate Impact Factor Information from Journal Websites. Antimicrob Agents Chemother. 2016 09; 60(9):5109-10. View Abstract
  76. ASM Journals Eliminate Impact Factor Information from Journal Websites. Infect Immun. 2016 09; 84(9):2407-8. View Abstract
  77. The aetiology of diarrhoea, pneumonia and respiratory colonization of HIV-exposed infants randomized to breast- or formula-feeding. Paediatr Int Child Health. 2016 Aug; 36(3):189-97. View Abstract
  78. Essential Microbiology for Wound Care. Clin Infect Dis. 2016 Oct 15; 63(8):1149. View Abstract
  79. ASM Journals Eliminate Impact Factor Information from Journal Websites. Microbiol Mol Biol Rev. 2016 09; 80(3):i-ii. View Abstract
  80. ASM Journals Eliminate Impact Factor Information from Journal Websites. mBio. 2016 07 11; 7(4). View Abstract
  81. ASM Journals Eliminate Impact Factor Information from Journal Websites. mSphere. 2016 Jul-Aug; 1(4). View Abstract
  82. ASM Journals Eliminate Impact Factor Information from Journal Websites. mSystems. 2016 Jul-Aug; 1(4). View Abstract
  83. ASM Journals Eliminate Impact Factor Information from Journal Websites. J Clin Microbiol. 2016 09; 54(9):2216-7. View Abstract
  84. Evaluation of the C6 Lyme Enzyme Immunoassay for the Diagnosis of Lyme Disease in Children and Adolescents. Clin Infect Dis. 2016 10 01; 63(7):922-8. View Abstract
  85. The Brief Case: Safe To Go Back in the Water? Vibrio parahaemolyticus Wound Infection Associated with Brackish Water. J Clin Microbiol. 2016 06; 54(6):1414-1415. View Abstract
  86. Closing the Brief Case: Safe To Go Back in the Water? Vibrio parahaemolyticus Wound Infection Associated with Brackish Water. J Clin Microbiol. 2016 06; 54(6):1672. View Abstract
  87. Pediatric Clinical Microbiology: It's the Little Things. J Clin Microbiol. 2016 06; 54(6):1412-1413. View Abstract
  88. Reply to "Case Reports May Be Declared Dead by the Journal of Clinical Microbiology, but They Are Alive and Well in JMM Case Reports". J Clin Microbiol. 2016 Feb; 54(2):503. View Abstract
  89. The Brief Case: a New Feature in Journal of Clinical Microbiology. J Clin Microbiol. 2016 Mar; 54(3):512. View Abstract
  90. Your Viral Past: A Comprehensive Method for Serological Profiling to Explore the Human Virome. Clin Chem. 2016 Mar; 62(3):426-7. View Abstract
  91. An Obituary for the Case Report in Journal of Clinical Microbiology. J Clin Microbiol. 2015 Aug; 53(8):2396-7. View Abstract
  92. The aetiology of diarrhoea, pneumonia and respiratory colonization of HIV-exposed infants randomized to breast- or formula-feeding. Paediatr Int Child Health. 2015 Jun 8; 2046905515Y0000000038. View Abstract
  93. Preface. Diagnostic testing for enteric pathogens. Clin Lab Med. 2015 Jun; 35(2):xi-xii. View Abstract
  94. Shiga Toxin Producing Escherichia coli. Clin Lab Med. 2015 Jun; 35(2):247-72. View Abstract
  95. Point-Counterpoint: Large Multiplex PCR Panels Should Be First-Line Tests for Detection of Respiratory and Intestinal Pathogens. J Clin Microbiol. 2015 Oct; 53(10):3110-5. View Abstract
  96. A happy birthday and a transition at the Journal of Clinical Microbiology. J Clin Microbiol. 2015 Jan; 53(1):2-3. View Abstract
  97. What's your subtype? The epidemiologic utility of bacterial whole-genome sequencing. Clin Chem. 2014 Apr; 60(4):586-8. View Abstract
  98. Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures. Nat Genet. 2014 Jan; 46(1):82-7. View Abstract
  99. Yield of fungal surveillance cultures in pediatric hematopoietic stem cell transplant patients: a retrospective analysis and survey of current practice. Clin Infect Dis. 2014 Feb; 58(3):365-71. View Abstract
  100. Interferon ?-release assays for diagnosis of latent tuberculosis in healthcare workers in low-incidence settings: pros and cons. Clin Chem. 2014 May; 60(5):714-8. View Abstract
  101. Polymerase chain reaction test for Clostridium difficile toxin B gene reveals similar prevalence rates in children with and without inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2013 Sep; 57(3):293-7. View Abstract
  102. Biographical feature: Eileen L. Randall, Ph.D. J Clin Microbiol. 2013 Nov; 51(11):3476-7. View Abstract
  103. Identifying antibiotic-resistant bacteria in hospitalized patients: what is the role of active-surveillance cultures? Clin Chem. 2013 Nov; 59(11):1556-60. View Abstract
  104. Changing epidemiology of methicillin-resistant Staphylococcus aureus colonization in paediatric intensive-care units. Epidemiol Infect. 2013 Sep; 141(9):1983-92. View Abstract
  105. Hand, foot, and mouth disease caused by coxsackievirus a6. Emerg Infect Dis. 2012 Oct; 18(10):1702-4. View Abstract
  106. John C. Sherris, M.D. J Clin Microbiol. 2012 Nov; 50(11):3416-7. View Abstract
  107. Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study. Pediatr Infect Dis J. 2012 Jul; 31(7):767-9. View Abstract
  108. Antibiotic resistance: how serious is the problem, and what can be done? Clin Chem. 2012 Aug; 58(8):1182-6. View Abstract
  109. Impact of in-hospital enteroviral polymerase chain reaction testing on the clinical management of children with meningitis. J Hosp Med. 2012 Sep; 7(7):517-20. View Abstract
  110. Photo quiz: an 11-year-old with abdominal pain. J Clin Microbiol. 2012 Apr; 50(4):1139, 1508. View Abstract
  111. Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection. J Infect Dis. 2012 Jun; 205(11):1709-18. View Abstract
  112. Molecular testing for infectious diseases should be done in the clinical microbiology laboratory. J Clin Microbiol. 2012 Jun; 50(6):1836-40. View Abstract
  113. A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity. PLoS One. 2012; 7(2):e31307. View Abstract
  114. Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. Nat Genet. 2011 Nov 13; 43(12):1275-80. View Abstract
  115. Improved sensitivity of a commercial reverse transcription-PCR test for subtyping of the 2009 H1N1 influenza A virus. J Clin Microbiol. 2011 Mar; 49(3):1188. View Abstract
  116. Shiga toxin-producing Escherichia coli in children: diagnosis and clinical manifestations of O157:H7 and non-O157:H7 infection. J Clin Microbiol. 2011 Mar; 49(3):955-9. View Abstract
  117. Streptococcus milleri group pleuropulmonary infection in children: computed tomographic findings and clinical features. J Comput Assist Tomogr. 2010 Nov-Dec; 34(6):927-32. View Abstract
  118. Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care units. J Clin Microbiol. 2010 Aug; 48(8):2957-9. View Abstract
  119. Trimethoprim in vitro antibacterial activity is not increased by adding sulfamethoxazole for pediatric Escherichia coli urinary tract infection. J Urol. 2010 Jul; 184(1):305-10. View Abstract
  120. Multicenter study of clinical performance of the 3M Rapid Detection RSV test. J Clin Microbiol. 2010 Jul; 48(7):2337-43. View Abstract
  121. Re-emergence of the type 1 pilus among Streptococcus pneumoniae isolates in Massachusetts, USA. Vaccine. 2010 Jul 05; 28(30):4842-6. View Abstract
  122. Test characteristics of commercial influenza assays for detecting pandemic influenza A (H1N1) in children. Pediatr Infect Dis J. 2010 Mar; 29(3):261-2. View Abstract
  123. Human metapneumovirus. Clin Lab Med. 2010 Mar; 30(1):131-48. View Abstract
  124. Swine-origin influenza a (H1N1) viral infection in children: initial chest radiographic findings. Radiology. 2010 Mar; 254(3):934-41. View Abstract
  125. Respiratory viruses in pediatric and adult populations. Preface. Clin Lab Med. 2009 Dec; 29(4):xi-xii. View Abstract
  126. Developments in tissue culture detection of respiratory viruses. Clin Lab Med. 2009 Dec; 29(4):623-34. View Abstract
  127. Relative impact of influenza and respiratory syncytial virus in young children. Pediatrics. 2009 Dec; 124(6):e1072-80. View Abstract
  128. Epidemiology and risk factors for Staphylococcus aureus colonization in children in the post-PCV7 era. BMC Infect Dis. 2009 Jul 11; 9:110. View Abstract
  129. Prospective multicenter study of the viral etiology of bronchiolitis in the emergency department. Acad Emerg Med. 2008 Feb; 15(2):111-8. View Abstract
  130. Association of the pneumococcal pilus with certain capsular serotypes but not with increased virulence. J Clin Microbiol. 2007 Jun; 45(6):1684-9. View Abstract
  131. Influenza and other respiratory virus-related emergency department visits among young children. Pediatrics. 2006 Jul; 118(1):e1-8. View Abstract
  132. Validation of syndromic surveillance for respiratory infections. Ann Emerg Med. 2006 Mar; 47(3):265.e1. View Abstract
  133. Impact of Burkholderia dolosa on lung function and survival in cystic fibrosis. Am J Respir Crit Care Med. 2006 Feb 15; 173(4):421-5. View Abstract
  134. Cerebrospinal latex agglutination fails to contribute to the microbiologic diagnosis of pretreated children with meningitis. Pediatr Infect Dis J. 2004 Aug; 23(8):786-8. View Abstract
  135. Pathology of human metapneumovirus infection: insights into the pathogenesis of a newly identified respiratory virus. Pediatr Dev Pathol. 2004 Sep-Oct; 7(5):478-86; discussion 421. View Abstract
  136. Human metapneumovirus in children tested at a tertiary-care hospital. J Infect Dis. 2004 Jul 01; 190(1):20-6. View Abstract
  137. Detection of multiple macrolide- and lincosamide-resistant strains of Streptococcus pyogenes from patients in the Boston area. J Clin Microbiol. 2004 Apr; 42(4):1559-63. View Abstract
  138. Incidence of outpatient visits and hospitalizations related to influenza in infants and young children. Pediatrics. 2004 Mar; 113(3 Pt 1):585-93. View Abstract
  139. Resistance of group B streptococcus to selected antibiotics, including erythromycin and clindamycin. J Clin Microbiol. 2004 Mar; 42(3):1263-4. View Abstract
  140. Human metapneumovirus--an important new respiratory virus. N Engl J Med. 2004 Jan 29; 350(5):431-3. View Abstract
  141. Cutting edge: inducible costimulator protein regulates both Th1 and Th2 responses to cutaneous leishmaniasis. J Immunol. 2002 Feb 01; 168(3):991-5. View Abstract
  142. ICOS is critical for CD40-mediated antibody class switching. Nature. 2001 Jan 04; 409(6816):102-5. View Abstract
  143. Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells. J Immunol. 2000 Nov 01; 165(9):5035-40. View Abstract
  144. Either B7 costimulation or IL-2 can elicit generation of primary alloreactive CTL. J Immunol. 2000 Sep 15; 165(6):3088-93. View Abstract
  145. Discrepant analysis: how can we test a test? J Clin Microbiol. 2000 Jun; 38(6):2027-9. View Abstract
  146. B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus. J Virol. 2000 Jan; 74(1):203-8. View Abstract
  147. Ox40-ligand has a critical costimulatory role in dendritic cell:T cell interactions. Immunity. 1999 Dec; 11(6):689-98. View Abstract
  148. Expression of B7 molecules in recipient, not donor, mice determines the survival of cardiac allografts. J Immunol. 1999 Oct 01; 163(7):3753-7. View Abstract
  149. B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). J Exp Med. 1999 Jan 18; 189(2):435-40. View Abstract
  150. The role of B7 co-stimulation in activation and differentiation of CD4+ and CD8+ T cells. Immunol Rev. 1998 Oct; 165:231-47. View Abstract
  151. IL-3 enhances both presentation of exogenous particulate antigen in association with class I major histocompatibility antigen and generation of primary tumor-specific cytolytic T lymphocytes. J Immunol. 1998 Jun 15; 160(12):5773-80. View Abstract
  152. Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes. Cancer Immunol Immunother. 1996 Jul; 42(6):362-8. View Abstract
  153. Analysis of the effect of cytokines (interleukins 2, 3, 4, and 6, granulocyte-monocyte colony-stimulating factor, and interferon-gamma) on generation of primary cytotoxic T lymphocytes against a weakly immunogenic tumor. Cell Immunol. 1995 Oct 15; 165(2):183-92. View Abstract
  154. B7-1 enhances natural killer cell-mediated cytotoxicity and inhibits tumor growth of a poorly immunogenic murine carcinoma. Cell Immunol. 1995 Oct 15; 165(2):217-24. View Abstract
  155. Synergistic effects of co-expression of the TH1 cytokines IL-2 and IFN-gamma on generation of murine tumor-reactive cytotoxic cells. Int J Cancer. 1995 May 29; 61(5):628-34. View Abstract
  156. Transfection of transforming growth factor-beta producing tumor EMT6 with interleukin-2 elicits tumor rejection and tumor reactive cytotoxic T-lymphocytes. J Immunother Emphasis Tumor Immunol. 1994 Apr; 15(3):155-64. View Abstract
  157. Isolation and expansion of tumor-infiltrating lymphocytes. Biotechniques. 1993 Dec; 15(6):970-2. View Abstract
  158. Interleukin-3 inhibits the generation of nonspecific killers by interleukin-2. J Immunother Emphasis Tumor Immunol. 1993 Nov; 14(4):293-7. View Abstract
  159. Coexpression of IL-2 and gamma-IFN enhances tumor immunity. Ann N Y Acad Sci. 1993 Aug 12; 690:349-51. View Abstract
  160. Transfection of TGF-beta producing tumors with IL-2 elicits tumor rejection. Ann N Y Acad Sci. 1993 Aug 12; 690:346-8. View Abstract
  161. Interleukin 3 enhances development of tumor-reactive cytotoxic cells by a CD4-dependent mechanism. Cancer Res. 1993 May 01; 53(9):2112-7. View Abstract
  162. CD4-class II major histocompatibility complex interaction does not enhance killing by a class I-restricted CD4+CD8+ cytotoxic T cell clone. Eur J Immunol. 1992 Sep; 22(9):2461-4. View Abstract
  163. Mechanism of cytolytic T lymphocyte killing of a low class I-expressing tumor. J Immunol. 1991 Aug 15; 147(4):1433-8. View Abstract
  164. Class-I MHC expression in the mouse lung carcinoma, line 1: a model for class-I inducible tumors. Int J Cancer Suppl. 1991; 6:82-9. View Abstract
  165. Thyroid hormone status regulates preprotachykinin-A gene expression in male rat anterior pituitary. Endocrinology. 1987 Oct; 121(4):1555-61. View Abstract

Contact Alexander McAdam

Print Profile