Alex Cuenca

Publications

1. Protocol for modeling innate immune training by repeated alum exposure in mice (adjuvant conditioning). STAR Protoc. 2026 Feb 19; 7(1):104390. View Abstract
2. Author Correction: Towards a reference cell atlas of liver diversity over the human lifespan. Nat Rev Gastroenterol Hepatol. 2026 Jan; 23(1):110. View Abstract
3. Adjuvant conditioning enhances neutrophil function while inducing a suppressive peritoneal macrophage phenotype. J Immunol. 2025 Dec 01; 214(12):3604-3617. View Abstract
4. Long-term outcomes after the mesenteric artery growth improves circulation (MAGIC) procedure for midaortic syndrome. Surgery. 2026 Feb; 190:109831. View Abstract
5. Towards a reference cell atlas of liver diversity over the human lifespan. Nat Rev Gastroenterol Hepatol. 2026 Jan; 23(1):97-109. View Abstract
6. Pediatric Liver Transplant: Anatomic, Imaging, and Surgical Considerations-A Report of the Pediatric LI-RADS Working Group, From the AJR Special Series on Critical Anatomy. AJR Am J Roentgenol. 2025 Aug 27. View Abstract
7. Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections. Immunity. 2025 Sep 09; 58(9):2190-2207.e13. View Abstract
8. Adjuvant conditioning shapes the adaptive immune response promoting immunotolerance via NLRP3/interleukin-1. iScience. 2025 Jun 20; 28(6):112653. View Abstract
9. Early Graft Loss With Suspected Seventh-Day Syndrome Following Pediatric Liver Transplantation. Pediatr Transplant. 2024 Aug; 28(5):e14818. View Abstract
10. Surgical management of liver tumors. Pediatr Blood Cancer. 2025 Apr; 72 Suppl 2:e31155. View Abstract
11. Effect of citizenship status on access to pediatric liver and kidney transplantation. Am J Transplant. 2024 Oct; 24(10):1868-1880. View Abstract
12. Metastatic pulmonary calcifications after pediatric liver transplantation. Pediatr Transplant. 2024 Feb; 28(1):e14693. View Abstract
13. Immediate extubation after pediatric liver transplantation: Update on a single-center experience. Pediatr Transplant. 2024 Feb; 28(1):e14669. View Abstract
14. Critical elements of pediatric liver cancer surgery. Semin Pediatr Surg. 2023 Oct; 32(5):151340. View Abstract
15. Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter. bioRxiv. 2023 Nov 21. View Abstract
16. Pediatric Organ Donation and Transplantation: Across the Care Continuum. Pediatrics. 2023 Aug 01; 152(2). View Abstract
17. Intragraft B cell differentiation during the development of tolerance to kidney allografts is associated with a regulatory B cell signature revealed by single cell transcriptomics. Am J Transplant. 2023 09; 23(9):1319-1330. View Abstract
18. Adjuvant conditioning induces an immunosuppressive milieu that delays alloislet rejection through the expansion of myeloid-derived suppressor cells. Am J Transplant. 2023 07; 23(7):935-945. View Abstract
19. Innate immune cellular therapeutics in transplantation. Front Transplant. 2023; 2. View Abstract
20. Outcomes of internal biliary diversion using cholecystocolostomy for patients with severe Alagille syndrome. J Surg Case Rep. 2022 Jul; 2022(7):rjac307. View Abstract
21. Organ allocation in pediatric abdominal transplant. Semin Pediatr Surg. 2022 Jun; 31(3):151180. View Abstract
22. Functional side-to-side splenorenal shunts to treat extrahepatic portal vein thrombosis in children. Am J Surg. 2022 07; 224(1 Pt B):530-534. View Abstract
23. Triple gallbladder with heterotopic gastric mucosa: a case report. BMC Pediatr. 2022 01 20; 22(1):52. View Abstract
24. Prenatal diagnosis of rapidly enlarging choledochal cyst with gastric outlet obstruction. J Surg Case Rep. 2021 Dec; 2021(12):rjab547. View Abstract
25. Midaortic syndrome and renovascular hypertension. Semin Pediatr Surg. 2021 Dec; 30(6):151124. View Abstract
26. Short Bowel Syndrome and Kidney Transplantation: Challenges, Outcomes, and the Use of Teduglutide. Case Rep Transplant. 2020; 2020:8819345. View Abstract
27. Resolution of a High Grade and Metastatic BK Polyomavirus-Associated Urothelial Cell Carcinoma Following Radical Allograft Nephroureterectomy and Immune Checkpoint Treatment: A Case Report. Transplant Proc. 2020 Nov; 52(9):2720-2725. View Abstract
28. Immediate administration of antiviral therapy after transplantation of hepatitis C-infected livers into uninfected recipients: Implications for therapeutic planning. Am J Transplant. 2020 06; 20(6):1619-1628. View Abstract
29. Pediatric liver transplant following near catastrophic head bleed: Lessons learned. Pediatr Transplant. 2020 03; 24(2):e13646. View Abstract
30. Giant Gastroschisis with Complete Liver Herniation: A Case Report of Two Patients. Case Rep Surg. 2019; 2019:4136214. View Abstract
31. Pediatric liver transplantation. Semin Pediatr Surg. 2017 Aug; 26(4):217-223. View Abstract
32. Clostridium difficile Infections after Blunt Trauma: A Different Patient Population? Surg Infect (Larchmt). 2015 Aug; 16(4):421-7. View Abstract
33. Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation. Immunology. 2015 Jun; 145(2):300-11. View Abstract
34. Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit. PLoS One. 2015; 10(5):e0126895. View Abstract
35. TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis. J Immunol. 2015 Feb 01; 194(3):1169-77. View Abstract
36. Delayed emergency myelopoiesis following polymicrobial sepsis in neonates. Innate Immun. 2015 May; 21(4):386-91. View Abstract
37. Omental flaps for coverage of sacral or gluteal defects: a useful and potentially underused tool. Am Surg. 2014 Jul; 80(7):e202-4. View Abstract
38. A better understanding of why murine models of trauma do not recapitulate the human syndrome. Crit Care Med. 2014 Jun; 42(6):1406-13. View Abstract
39. Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia. J Immunol. 2014 Jun 15; 192(12):6111-9. View Abstract
40. Host responses to sepsis vary in different low-lethality murine models. PLoS One. 2014; 9(5):e94404. View Abstract
41. Protective immunity and defects in the neonatal and elderly immune response to sepsis. J Immunol. 2014 Apr 01; 192(7):3156-65. View Abstract
42. Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma. J Trauma Acute Care Surg. 2014 Jan; 76(1):21-9; discussion 29-30. View Abstract
43. Aged mice are unable to mount an effective myeloid response to sepsis. J Immunol. 2014 Jan 15; 192(2):612-22. View Abstract
44. Is there value in plasma cytokine measurements in patients with severe trauma and sepsis? Methods. 2013 May 15; 61(1):3-9. View Abstract
45. Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients. Crit Care Med. 2013 May; 41(5):1175-85. View Abstract
46. Acute kidney injury is associated with early cytokine changes after trauma. J Trauma Acute Care Surg. 2013 Apr; 74(4):1005-13. View Abstract
47. Identification and description of a novel murine model for polytrauma and shock. Crit Care Med. 2013 Apr; 41(4):1075-85. View Abstract
48. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3507-12. View Abstract
49. Role of innate immunity in neonatal infection. Am J Perinatol. 2013 Feb; 30(2):105-12. View Abstract
50. A genomic analysis of Clostridium difficile infections in blunt trauma patients. J Trauma Acute Care Surg. 2013 Jan; 74(1):334-8. View Abstract
51. Soybean oil: a potentially new intravascular perfusate. Perfusion. 2013 Mar; 28(2):160-6. View Abstract
52. The acute immunological response to blood transfusion is influenced by polymicrobial sepsis. Shock. 2012 Dec; 38(6):598-606. View Abstract
53. Pediatric pancreatic trauma: trending toward nonoperative management? Am Surg. 2012 Nov; 78(11):1204-10. View Abstract
54. Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care. J Trauma Acute Care Surg. 2012 Jun; 72(6):1491-501. View Abstract
55. Myeloid-derived suppressor cells in sepsis: friend or foe? Intensive Care Med. 2012 Jun; 38(6):928-30. View Abstract
56. Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg. 2012 May; 255(5):993-9. View Abstract
57. "Pulling the plug"--management of meconium plug syndrome in neonates. J Surg Res. 2012 Jun 15; 175(2):e43-6. View Abstract
58. Obese patients show a depressed cytokine profile following severe blunt injury. Shock. 2012 Mar; 37(3):253-6. View Abstract
59. A genomic storm in critically injured humans. J Exp Med. 2011 Dec 19; 208(13):2581-90. View Abstract
60. Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest. 2011 Dec; 91(12):1787-95. View Abstract
61. The Glue Grant experience: characterizing the post injury genomic response. Eur J Trauma Emerg Surg. 2011 Dec; 37(6):549-58. View Abstract
62. B cells enhance early innate immune responses during bacterial sepsis. J Exp Med. 2011 Aug 01; 208(8):1673-82. View Abstract
63. Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling. J Immunol. 2011 Jul 15; 187(2):911-8. View Abstract
64. Critical role for CXC ligand 10/CXC receptor 3 signaling in the murine neonatal response to sepsis. Infect Immun. 2011 Jul; 79(7):2746-54. View Abstract
65. The usefulness of the upper gastrointestinal series in the pediatric patient before anti-reflux procedure or gastrostomy tube placement. J Surg Res. 2011 Oct; 170(2):247-52. View Abstract
66. Sepsis induces early alterations in innate immunity that impact mortality to secondary infection. J Immunol. 2011 Jan 01; 186(1):195-202. View Abstract
67. A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol Med. 2011 Mar-Apr; 17(3-4):281-92. View Abstract
68. Cecal ligation and puncture. Curr Protoc Immunol. 2010 Nov; Chapter 19:Unit 19.13. View Abstract
69. Do Tregs link sepsis to tumor growth? Blood. 2010 Jun 03; 115(22):4324-5. View Abstract
70. Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling. J Immunol. 2010 Mar 01; 184(5):2247-51. View Abstract
71. Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10. J Exp Med. 2010 Feb 15; 207(2):319-26. View Abstract
72. Diminishing role of contrast enema in simple meconium ileus. J Pediatr Surg. 2009 Nov; 44(11):2130-2. View Abstract
73. Equestrian injuries in children. J Pediatr Surg. 2009 Jan; 44(1):148-50. View Abstract
74. Pulmonary surgery in cystic fibrosis. Semin Pediatr Surg. 2008 Feb; 17(1):60-5. View Abstract
75. Emerging implications of nanotechnology on cancer diagnostics and therapeutics. Cancer. 2006 Aug 01; 107(3):459-66. View Abstract
76. In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity. Blood. 2006 Apr 01; 107(7):2871-8. View Abstract
77. Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4+ T-cell tolerance. Blood. 2005 Feb 01; 105(3):1135-43. View Abstract
78. Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens. Cancer Res. 2003 Dec 15; 63(24):9007-15. View Abstract
79. A critical role for Stat3 signaling in immune tolerance. Immunity. 2003 Sep; 19(3):425-36. View Abstract
80. Calorie restriction influences cell cycle protein expression and DNA synthesis during liver regeneration. Exp Biol Med (Maywood). 2001 Dec; 226(11):1061-7. View Abstract
81. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood. 2001 Aug 15; 98(4):1070-7. View Abstract
82. Pancreas transplant graft evaluation using the MIBI scan--a useful tool. Transplant Proc. 1998 Mar; 30(2):257-60. View Abstract
83. Pancreaticojejunostomy versus controlled pancreaticocutaneous fistula in pancreaticoduodenectomy for periampullary carcinoma. Am J Surg. 1995 Jun; 169(6):585-8. View Abstract
Show All Publications Show Fewer Publications