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Related Research Units

Research Overview

Dr. Alan Leichtner's research focuses on developing and evaluating treatments for inflammatory bowel disease, gastroesophageal reflux, and celiac disease in children.

 

Research Background

Dr. Alan Leichtner is a graduate of Harvard Medical School. He completed an internship, residency and fellowship at Boston Children's Hospital.

 

Education

Medical School

Harvard Medical School
1977 Boston MA

Internship

Boston Children's Hospital
1978 Boston MA

Residency

Boston Children's Hospital
1980 Boston MA

Fellowship

Gastroenterology Boston Children's Hospital
1983 Boston MA

Publications

  1. Sentinel events in pediatric hepatology: A pilot simulation curriculum. JPGN Rep. 2026 May; 7(2):332-339. View Abstract
  2. "If You Don't Care, Why Should I?": Residents' Perspectives on Attending Actions that Influence the Educational Alliance. Acad Pediatr. 2026 03; 26(2):103184. View Abstract
  3. From Bystander-to-Upstander: A Novel Intervention Framework to Address Microaggressions in a Pediatric Academic Medical Center. Acad Pediatr. 2025 Sep-Oct; 25(7):102630. View Abstract
  4. 'Blood and guts': Interleaving gastroenterology and haematology physiology. Med Educ. 2024 11; 58(11):1393-1394. View Abstract
  5. The Closing of an Academic Children's Hospital: Ethical Considerations for Graduate Medical Education. J Grad Med Educ. 2024 Aug; 16(4):395-398. View Abstract
  6. How to define yourself as a medical educator along the path to academic promotion. J Pediatr Gastroenterol Nutr. 2024 Aug; 79(2):202-205. View Abstract
  7. Lost in the pandemic: COVID-19's impact on health professions educators. Clin Teach. 2024 Oct; 21(5):e13764. View Abstract
  8. Lack of standardization and faculty development in pediatric colonoscopy: A qualitative study. J Pediatr Gastroenterol Nutr. 2024 04; 78(4):948-956. View Abstract
  9. Beyond the Workshop: Results From a Longitudinal, Interprofessional Teaching Certificate Program. J Med Educ Curric Dev. 2023 Jan-Dec; 10:23821205231205433. View Abstract
  10. Cytotoxic T Lymphocyte Antigen 4 Haploinsufficiency Presenting As Refractory Celiac-Like Disease: Case Report. Front Immunol. 2022; 13:894648. View Abstract
  11. Creating a health equity and inclusion office in an academic pediatric medical center: priorities addressed and lessons learned. Pediatr Radiol. 2022 08; 52(9):1776-1785. View Abstract
  12. Non-responsive celiac disease in children on a gluten free diet. World J Gastroenterol. 2021 Apr 07; 27(13):1311-1320. View Abstract
  13. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on Entrustable Professional Activities: Development of Pediatric Gastroenterology, Hepatology, and Nutrition Entrustable Professional Activities. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):136-143. View Abstract
  14. Pediatric Gastroenterology, Hepatology, and Nutrition Entrustable Professional Activities: Development of an Assessment Tool and Curricular Resources. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):e40-e45. View Abstract
  15. Visiting Jack: Mixed Methods Evaluation of a Virtual Home Visit Curriculum With a Child With Medical Complexity. Acad Pediatr. 2020 Sep - Oct; 20(7):1020-1028. View Abstract
  16. Use of Nazi torture device image in digital scholarship article. Med Teach. 2020 06; 42(6):717-718. View Abstract
  17. Training in Endoscopy: Coaching, Deliberate Practice, and Reflection. J Pediatr Gastroenterol Nutr. 2019 03; 68(3):298-300. View Abstract
  18. Interprofessional provider educational needs and preferences regarding the provision of sexual and reproductive health care in cystic fibrosis. J Cyst Fibros. 2019 09; 18(5):671-676. View Abstract
  19. Red Spot Lesions in the Duodenal Bulb Are a Highly Specific Endoscopic Sign of Celiac Disease: A Prospective Study. J Pediatr Gastroenterol Nutr. 2019 02; 68(2):251-255. View Abstract
  20. Lack of Follow-up of Pediatric Patients With Celiac Disease. Clin Gastroenterol Hepatol. 2019 11; 17(12):2603-2604. View Abstract
  21. Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects. J Allergy Clin Immunol. 2018 12; 142(6):1932-1946. View Abstract
  22. Objective Assessment of Fellows: Doable and Worth Doing. J Pediatr Gastroenterol Nutr. 2017 04; 64(4):498-500. View Abstract
  23. Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 02; 64(2):286-291. View Abstract
  24. The Boston Children's Hospital Academy: Development and Initial Assessment of a Hospital-Based Teaching Academy. Acad Med. 2016 12; 91(12):1651-1654. View Abstract
  25. 'Constipation Challenge' game improves guideline knowledge and implementation. Med Educ. 2016 May; 50(5):589-90. View Abstract
  26. Shared care: a quality improvement initiative to optimize primary care management of constipation. Pediatrics. 2015 May; 135(5):e1300-7. View Abstract
  27. Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. 2015 Dec; 64(12):1889-97. View Abstract
  28. Assessment tools: the next frontier in competency-based medical education. J Pediatr Gastroenterol Nutr. 2014 Oct; 59(4):425-7. View Abstract
  29. Graduate medical education in humanism and professionalism: a needs assessment survey of pediatric gastroenterology fellows. J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):34-7. View Abstract
  30. NASPGHAN guidelines for training in pediatric gastroenterology. J Pediatr Gastroenterol Nutr. 2013 Jan; 56 Suppl 1:S1-8. View Abstract
  31. Navigating the gluten-free diet in college. J Pediatr Gastroenterol Nutr. 2012 Dec; 55(6):740-4. View Abstract
  32. Multicenter study on season of birth and celiac disease: evidence for a new theoretical model of pathogenesis. J Pediatr. 2013 Mar; 162(3):501-4. View Abstract
  33. Pediatric gastroenterology fellowship: is the match working? J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):243-4. View Abstract
  34. Variability of histopathological changes in childhood celiac disease. Am J Gastroenterol. 2010 Jan; 105(1):207-12. View Abstract
  35. Restorative proctocolectomy and ileal pouch-anal anastomosis in children. Dis Colon Rectum. 2009 Sep; 52(9):1645-9. View Abstract
  36. First evidence of a possible association between gastric acid suppression during pregnancy and childhood asthma: a population-based register study. Clin Exp Allergy. 2009 Feb; 39(2):246-53. View Abstract
  37. Desquamative enteropathy and pyloric atresia without skin disease caused by a novel intracellular beta4 integrin mutation. J Pediatr Gastroenterol Nutr. 2008 Nov; 47(5):585-91. View Abstract
  38. Clinical significance of colonic intraepithelial lymphocytosis in a pediatric population. Mod Pathol. 2009 Jan; 22(1):13-20. View Abstract
  39. Fellowship training in pediatric gastroenterology in the United States: where are we going? Does one size fit all? J Pediatr Gastroenterol Nutr. 2008 Sep; 47(3):274-6. View Abstract
  40. Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases. J Pediatr. 2007 Apr; 150(4):376-82. View Abstract
  41. Celiac disease presenting with chilblains in an adolescent girl. Pediatr Dermatol. 2006 Sep-Oct; 23(5):451-4. View Abstract
  42. Serologic testing with ANCA, ASCA, and anti-OmpC in children and young adults with Crohn's disease and ulcerative colitis: diagnostic value and correlation with disease phenotype. Am J Gastroenterol. 2004 Nov; 99(11):2235-41. View Abstract
  43. Depressive symptoms and inflammatory bowel disease in children and adolescents: a cross-sectional study. J Pediatr Gastroenterol Nutr. 2004 Oct; 39(4):395-403. View Abstract
  44. Pediatric patients with untreated ulcerative colitis may present initially with unusual morphologic findings. Am J Surg Pathol. 2004 Feb; 28(2):190-7. View Abstract
  45. Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex, and their combination. J Am Acad Child Adolesc Psychiatry. 2003 Oct; 42(10):1227-33. View Abstract
  46. Complementary medicine use in children and young adults with inflammatory bowel disease. Am J Gastroenterol. 2002 Feb; 97(2):382-8. View Abstract
  47. Elevated serum hepatocyte growth factor in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2001 Nov; 33(5):548-53. View Abstract
  48. Oral tacrolimus treatment of severe colitis in children. J Pediatr. 2000 Dec; 137(6):794-9. View Abstract
  49. Allergic esophagitis in children: a clinicopathological entity. Am J Surg Pathol. 1999 Apr; 23(4):390-6. View Abstract
  50. Human intestinal M cells display the sialyl Lewis A antigen. Infect Immun. 1999 Feb; 67(2):946-53. View Abstract
  51. Elevated serum vascular endothelial growth factor in children and young adults with Crohn's disease. Dig Dis Sci. 1999 Feb; 44(2):424-30. View Abstract
  52. Quality-of-life assessment after ileoanal pull-through for ulcerative colitis and familial adenomatous polyposis. J Pediatr Surg. 1999 Jan; 34(1):163-6. View Abstract
  53. Aluminum in large and small volume parenterals used in total parenteral nutrition: response to the Food and Drug Administration notice of proposed rule by the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr. 1998 Oct; 27(4):457-60. View Abstract
  54. Gastrointestinal manifestations of vascular anomalies in childhood: varied etiologies require multiple therapeutic modalities. J Pediatr Surg. 1998 Jul; 33(7):1163-7. View Abstract
  55. Serum leptin in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 1998 May; 26(5):500-5. View Abstract
  56. Vitamins A and E serum levels in children and young adults with inflammatory bowel disease: effect of disease activity. J Pediatr Gastroenterol Nutr. 1998 Feb; 26(2):129-35. View Abstract
  57. Clinical outcome of ulcerative proctitis in children. J Pediatr Gastroenterol Nutr. 1997 Aug; 25(2):149-52. View Abstract
  58. Surgery for Crohn's disease in infants and children. J Pediatr Surg. 1997 Jul; 32(7):1063-7; discussion 1067-8. View Abstract
  59. Serum basic fibroblast growth factor in pediatric Crohn's disease. Implications for wound healing. Dig Dis Sci. 1997 Feb; 42(2):378-86. View Abstract
  60. Complications following percutaneous endoscopic gastrostomy and subsequent catheter replacement in children and young adults. Gastrointest Endosc. 1997 Jan; 45(1):64-71. View Abstract
  61. Tacrolimus (FK-506) treatment of fulminant colitis in a child. J Pediatr Gastroenterol Nutr. 1996 Oct; 23(3):329-33. View Abstract
  62. Elevation of serum interleukin-6 but not serum-soluble interleukin-2 receptor in children with Crohn's disease. J Pediatr Gastroenterol Nutr. 1996 Aug; 23(2):164-71. View Abstract
  63. Gastric and esophageal intraepithelial lymphocytes in pediatric celiac disease. Am J Surg Pathol. 1996 Jul; 20(7):865-70. View Abstract
  64. Treatment of pediatric autoimmune enteropathy with tacrolimus (FK506). Gastroenterology. 1996 Jul; 111(1):237-43. View Abstract
  65. Long-term hepatic regeneration and function in infants and children following liver resection. J Am Coll Surg. 1996 Jun; 182(6):515-9. View Abstract
  66. Intraoperative enteroscopy in the diagnosis of partial intestinal obstruction in infancy. Dig Dis Sci. 1995 Oct; 40(10):2236-8. View Abstract
  67. Aminosalicylates for the treatment of inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 1995 Oct; 21(3):245-52. View Abstract
  68. Endoscopic ligation of esophageal varices in children. J Pediatr Gastroenterol Nutr. 1995 Feb; 20(2):202-8. View Abstract
  69. Allergic colitis in infants. J Pediatr. 1995 Feb; 126(2):163-70. View Abstract
  70. Medical therapies for pediatric gastrointestinal disease. Subcommittee on Therapeutics of the Patient Care Committee North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr. 1994 Apr; 18(3):269. View Abstract
  71. Long-term nutritional and metabolic consequences of pancreaticoduodenectomy in children. Surgery. 1994 Mar; 115(3):382-8. View Abstract
  72. Allergic proctocolitis in infants: a prospective clinicopathologic biopsy study. Hum Pathol. 1993 Jun; 24(6):668-74. View Abstract
  73. The antegrade colonogram: extending the small bowel follow through for children suspected of having colonic disease. Pediatr Radiol. 1992; 22(8):573-6. View Abstract
  74. Pancreatitis following scoliosis surgery in children and young adults. J Pediatr Orthop. 1991 Sep-Oct; 11(5):594-8. View Abstract
  75. Longitudinal assessment of type I procollagen in children with inflammatory bowel disease subjected to surgery. J Pediatr Gastroenterol Nutr. 1989 Jan; 8(1):68-74. View Abstract
  76. Carbohydrate malabsorption following fruit juice ingestion in young children. Pediatrics. 1988 Jul; 82(1):64-8. View Abstract
  77. Relationship of type I procollagen to corticosteroid therapy in children with inflammatory bowel disease. J Pediatr. 1988 Jun; 112(6):893-8. View Abstract
  78. Clinical and laboratory correlates of esophagitis in young children. J Pediatr Gastroenterol Nutr. 1988 Jan-Feb; 7(1):52-6. View Abstract
  79. Hypertension associated with unilateral hydronephrosis as a complication of Crohn's disease. J Pediatr Surg. 1987 Nov; 22(11):1049-50. View Abstract
  80. Cyclosporine treatment of autoimmune chronic active hepatitis. Gastroenterology. 1987 Oct; 93(4):890-3. View Abstract
  81. Type 1 procollagen as a biochemical marker of growth in children with inflammatory bowel disease. J Pediatr. 1986 Oct; 109(4):619-24. View Abstract
  82. Effect of metoclopramide on prolonged intraesophageal pH testing in infants with gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 1986 Sep-Oct; 5(5):716-20. View Abstract
  83. Chronic diarrhea associated with hypogammaglobulinemia and enteropathy in infants and children. Dig Dis Sci. 1985 Dec; 30(12):1149-55. View Abstract
  84. Cerebral vascular accident during the recovery phase of hemolytic uremic syndrome. Int J Pediatr Nephrol. 1985 Oct-Dec; 6(4):287-8. View Abstract
  85. Discordance for biliary atresia in two sets of monozygotic twins. J Pediatr. 1985 Sep; 107(3):420-2. View Abstract
  86. Apple juice. An unappreciated cause of chronic diarrhea. Am J Dis Child. 1985 May; 139(5):503-5. View Abstract
  87. Pseudopheochromocytoma and cardiac arrest associated with phenylpropanolamine. JAMA. 1985 Mar 15; 253(11):1609-10. View Abstract
  88. Recent advances in diagnosis and treatment of gastrointestinal hemorrhage in infants and children. J Pediatr. 1985 Jan; 106(1):1-9. View Abstract
  89. Regulation of low density lipoprotein receptor function in a human hepatoma cell line. Hepatology. 1984 Sep-Oct; 4(5):897-901. View Abstract
  90. Addition of a mannose-6-phosphate-containing oligosaccharide alters cellular processing of low density lipoprotein by parental and LDL-receptor-defective Chinese hamster ovary cells. J Cell Sci. 1984 Jun; 68:183-94. View Abstract
  91. Horizontal nonparenteral spread of hepatitis B among children. Ann Intern Med. 1981 Mar; 94(3):346-9. View Abstract

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